Sharing the same challenges. from diagnosis, the seeds of better health

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1 from diagnosis, the seeds of better health Sharing the same challenges

2 Your daily guide VITEK 2 technology is like a lighthouse a strong and universal symbol of trust, knowledge and far-range vision. biomérieux is committed to delivering relevant microbiology solutions that empower clinical decisions. This commitment has been our pride for over 40 years. Our efforts are dedicated to developing innovative products in the field of microbial identification and susceptibility testing. Our solutions match your expectations as medical knowledge and technology continuously move forward. Our goal is the same as yours: finding new and better ways to improve overall patient care. Identifying bacterial resistance to enhance clinical guidance Accurate microbial identification is the first step in achieving this goal. biomérieux is strongly anchored in this field with more than 40 years of gold standard identification and susceptibility testing know-how. biomérieux is a pioneer in the development of Expert Systems. Capability to detect resistance mechanisms is crucial to avoid therapeutic failure. The VITEK 2 Advanced Expert System provides accurate fingerprint recognition of bacterial resistance mechanisms and phenotypes. Faster results for relevant antibiotic therapy Same-day results through rapid identification and antibiotic susceptibility testing are made possible by automation and contribute to improved patient outcomes. 1, 2 The most important task facing the microbiology laboratory is reporting rapid, accurate and clinically relevant results. 1. Barenfanger J, et al., Clinical and Financial Benefits of Rapid Bacterial Identification and Antimicrobial Susceptibility Testing. J Clin Micro, May 1999, Thomas J, et al., Outcomes Assessment Measuring Clinical and Financial Impact of Microbiologic Based Protocols : C ) Comparing Antimicrobial Susceptibility Reporting. ASM 2000, Paper C-358.

3 Microbiology faces a broad spectrum of challenges... Anti-infective treatments represent a significant burden for hospital healthcare budgets. Microbiology laboratories play a key role in helping to control the proper use of antibiotics. Rapid and accurate reporting of antibiotic susceptibility test results guides relevant therapeutic decisions. Targeted antibiotic therapy depends on rapid, reliable microbiology results. Increased healthcare costs Antibiotic misuse Hospital-acquired infections Increasing microbial resistances The microbiology laboratory has assumed a more prominent role in the fight against hospital-acquired infections. Through resistance mechanism detection, microbiologists are at the forefront of the fight against bacterial resistance, a concern for any healthcare institution. The increase in bacterial resistance is challenging our most effective antibiotics. Identifying bacterial resistance as early as possible allows for implementation of proactive measures and therapeutic adjustments. This helps to prevent treatment failures and reduces emerging resistance. In this challenging environment, microbiology must respond quickly and implement new technology and processes to provide the best patient care in the most efficient way. that impact your daily activities. Report relevant results rapidly Be confident in the test results reported Ensure lab efficiency Be the expert in microbiology

4 The new automated ID/AST system to access VITEK 2 technology and meet your daily challenges! Ready-to-go in a sm 3 Steps to Set Up High level of automation Minimum hands-on and training time Pre-barcoded test cards ensure secure information traceability from specimen to result Minimal hands-on Traceability Load and go

5 technology art design VITEK 2 Compact connects to STELLARA Allows real-time connectivity, bringing laboratory results directly to clinicians via a wireless PDA Enables clinicians to optimize therapy for better patient care Visit for a demonstration Powered by TheraDoc 2 instrument sizes adapted to your laboratory: VITEK 2 Compact 30 VITEK 2 Compact 60 A compact design for optimal space savings: Height: 24" (60 cm) / Width: 28" (72 cm) Depth: 27" (68 cm) / Weight: 165 lbs (75kg) 2 Clicks to Access Your Daily Work Intuitive, icon-driven software Routine tasks are one to two clicks away Familiar Windows format 1 Screen to Get Expert Advice Easy graphical representation shows phenotype match, like a fi ngerprint One click for result validation

6 2005 BIOMÉRIEUX, INC. VITEK IS A REGISTERED TRADEMARK, AND THE LOGO IS A REGISTERED AND PROTECTED TRADEMARK OF BIOMÉRIEUX SA OR ONE OF ITS SUBSIDIARIES, ADVANCED COLORIMETRY, ADVANCED EXPERT AND EMPOWER CLINICAL DECISIONS ARE TRADEMARKS OF BIOMÉRIEUX, THERADOC IS A REGISTERED TRADEMARK OF THERADOC, INC. AND WINDOWS IS A REGISTERED TRADEMARK OF MICROSOFT CORPORATION PRINTED IN U.S.A. VTK Report it rapidly! VITEK 2 Card A unique concept for same-day results The VITEK 2 card enhances: Laboratory efficiency Highest level of automation No reagent addition Closed disposable for optimal user safety Pre-applied card barcodes for maximum traceability Same-day result Test card is read kinetically every 15 minutes for optimum time to result Mean time to ID/AST result is six to eight hours Get it right! Advanced Colorimetry A unique identification technology to enhance performance Over 98% of routine clinical isolates identified with a single system New colorimetric substrates developed Highest discrimination between species Lowest rate of multiple choice and mis-identified species Low rate of off-line tests biomérieux, Inc. 100 Rodolphe Street Durham, NC U.S.A. Tel: (800) Fax: (800) biomérieux Canada, Inc Henri-Bourassa Boulevard West St. Laurent (Québec) H4S 1P7 Canada Tel: (1) Fax: (1) Keep it relevant! Advanced Expert System A unique interpretation software to ensure confidence in results Antibiotic Susceptibility Test results coupled with Advanced Expert System: an optimal level of information for the best clinical decision On average, there are five to seven MIC doubling dilutions per antibiotic Extended MIC range enables low-level resistance detection Resistance-oriented results which highlight unusual phenotypes Deduced antibiotic results to meet formulary requirements Every result is checked every time UNPARALLELED POWER > 100,000 reference database > 2,000 referenced phenotypes > 20,000 MIC distributions > 100 resistance mechanisms detected