Results of Applications for the 2016 Integrated Thematic Projects at Academia Sinica Announced

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1 Results of Applications for the 2016 Integrated Thematic Projects at Academia Announced There is a total of 23 applications for the 2016 Thematic Projects (7 from Division of Mathematics and Physical Sciences; 12 from Division of Life Sciences; 4 from Division of Humanities and Social Sciences). The applications require a budget of NT$209,418,000 in total (NT$77,986,000 for Division of Mathematics and Physical Sciences; NT$110,670,000 for Division of Life Sciences; NT$20,762,000 for Division of Humanities and Social Sciences). Of all the applications, 13 were approved in the meetings of the Second-round Review and Budget Review, including 5 from Division of Mathematics and Physical Sciences, 5 from Division of Life Sciences, and 3 from Division of Humanities and Social Sciences. The total approved budget amounts to NT$93,515,000 (NT$37,870,000 for Division of Mathematics and Physical Sciences; NT$46,645,000 for Division of Life Sciences; NT$9,000,000 for Division of Humanities and Social Sciences). Please refer to the following table for detailed information. A. Division of Mathematics and Physical Sciences: (5 projects) Project No. Title of Thematic Project (1) Project Director (2) Sub-project PI (3) Co-PI (4) Associate PI Institution AS-105-TP-A03 Manipulating the electronic structures of quantum materials by magnetic impurities, Landau levels, and external strain (1) Wei-Bin Su (3) Woei Wu Pai Physics, Center for Condensed Matter Sciences, A03-1 Studies of electronic structures of Pb quantum films possessing Landau levels at interface and buried magnetic impurities (2) Jason Chia-Seng Chang Physics, A03-2 Studies of strain-induced Landau levels in suspended graphene using face-to-face dual-probe scanning tunneling microscopy A03-3 Exploring the charge dynamics in quantum matters by Landau level spectroscopy (2) Wei-Bin Su Physics, (2) Hsiang-Lin Liu Department of Physics, National Taiwan Normal AS-105-TP-A04 Multi-Scale Boundary Mechanics in Development and Diseases (1) Chin-Lin Guo (3) Kung-Hsuan Lin (3) Pei-Lin Cheng Physics, Physics, Molecular 1

2 A04-1 Boundary Mechanics in Epithelial homeostasis and Branching Morphogenesis (2) Chin-Lin Guo Physics, A04-2 Mechanistic Profiles in Self-driven Morphogenesis System (2) Ying-Chih Chang (3) Pei-Lin Cheng Genomics Research Institue of Molecular, AS-105-TP-A05 High Performance Chemical Probe-based Glycoproteomics to Illuminate Patho-physiological Transformation in B Cell Lymphomagenesis and Treatment Responses (1) Yu-Ju Chen (3) Hwei-Fang Tien (3) Shang-Ju Wu Chemistry, Internal Medicine, Hospital Internal Medicine, Hospital A05-1 Global and targeted MS-based sialo-glycoproteomics to identify physiological carriers of functionally relevant sialo-glycotopes (2) Yu-Ju Chen (4) Kay-Hooi Khoo Chemistry, Biological A05-2 Development of Molecular Probes and Synthesis of LacNAc-based Carbohydrate Ligands for Understanding the Interactions of Galectins and Siglecs with Their Counterparts on B-cell Lymphoma (2) Chun-Cheng Lin (4) Chun-Hung Lin Department of Chemistry, National Tsing Hua Biological A05-3 Molecular Links Between Glycoproteins and Glycan-binding Proteins in B Cell Lymphomagenesis and Treatment Responses (2) Kuo-I Lin (4)Takashi Angata Genomics Research Biological, AS-105-TP-A06 Integrative platforms for investigation of cell-cell communications and cell transformation under physico-chemical stimulations A06-1 Using optical techniques and microfluidic devices to study the membrane tunneling nanotube communication between cancer stem cells and stromal cells A06-2 Effect of electric-field stimulation on the transepithelial potential and morphogenesis of pulmonary stem cell (1) Chau-Hwang Lee Research Center for Applied Sciences, (2) Chau-Hwang Lee Research Center for Applied Sciences, (2) Ji-Yen Cheng Research Center for Applied Sciences, 2

3 A06-3 Study Physical Property Variation of Lung Cells Influenced by Microenvironments and Cell-Cell Communication A06-4 The role of membrane tunneling nanotubes in establishing intercellular communication of pancreatic cancer stem cells A06-5 Malignant transformation of lung progenitor cell under the dome To study the synergistic hazard and carcinogenic mechanisms of PM0.1 and PM2.5 with environmental pollutants on lung progenitor cells (2) Yi-Chung Tung Research Center for Applied Sciences, (2) Chia-Ning Shen Genomics Research (2) Huei-Wen Chen Toxicology, National Taiwan AS-105-TP-A07 Activity monitoring and interactive presentation design for active aging: sensor platform, activity mining and interactive art (1) Yu-Chee Tseng (3) Ling-Jyh Chen Research Center for Information Technology Innovation, Information Science, A07-1 Design and implementation of a wearable sensor platform for active aging (2)Yu-Chee Tseng (3) Chih-Wei Yi Research Center for Information Technology Innovation, Compute Science, National Chiao Tung A07-2 Individual and social group activity monitoring and mining for active aging (2) Ling-Jyh Chen (3) Wen-Chih Peng Information Science, Compute Science, National Chiao Tung A07-3 Interactive presentation and art design based on activity monitoring for active aging (2) Yi-Bing Lin (3) Chih-Chieh Huang Ministry of Science and Technology Department of Industrial Design, Chung Hua 3

4 B. Division of Life Sciences:(5 projects) Project No. Title of Thematic Project (1) Project Director (2) Sub-project PI (3) Co-PI (4) Associate PI Institution AS-105-TP-B03 AS-105-TP-B04 Roles of RNA processing in plant sexual reproduction B03-1 Impacts of Arabidopsis CstF64 mediated pre-mrna 3 -end processing on genes involved in floral development B03-2 Temperature-responsive alternative splicing in flowering time control B03-3 Investigation of Intra-cellular Trafficking of Mobile mrna Control of Mitochondrial Function and Structure in tissue integrity B04-1 Maintenance of Mitochondrial DNA and Function by DNA Topoisomerase IIIα B04-2 Control of mitochondria in germline stem cell aging B04-3 Insulin regulation of a nuclear encoded transmembrane protein targeting to mitochondria B04-4 Structure and function of mitochondria studied by electron microscopy (1) Guang-Yuh Jauh Plant and Microbial Biology, (2) Guang-Yuh Jauh Plant and Microbial Biology, (2) Shih-Long Tu Plant and Microbial Biology, (2) Tien-Shin Yu Plant and Microbial Biology, (1) Tao-Shih Hsieh Cellular (2) Hsieh Tao-Shih Cellular (2) Hwei-Jan Hsu Cellular (2) Yi-Ching Lee Cellular (2) Fu Chi-Yu Cellular AS-105-TP-B05 To delineate how bacterial pathogenicity and inflammation are under the control of gastrointestinal mucosal glycosylation (1)Chun-Hung Lin Biological B05-1 Molecular Exchange and Underlying Mechanism of Helicobacter plylori and Streptococcus gallolyticus with their Gastrointestinal Host (2) Chun-Hung Lin (4) Ming-Shiang Wu Biological Department of Internal Medicine, 4

5 Hospital B05-2 High Throughput Precision Glycomics for Delineation of Gastrointestinal Fucosylated, Sialylated and Sulfated Glycotopes B05-3 Role of galectins in regulation of mucosal immunity and inflammation (2) Kay-Hooi Khoo Biological (2) Fu-Tong Liu Biomedical Sciences, B05-4 Interplay of stromal cells and dendritic cells (DCs) in controlling H. pylori-mediated mucosal inflammation and gastric cancer (2) Shau-Ku Huang (3) Deng-Chyang Wu (4) Mou-Chieh Kao (4) Lin-Li Chang DEHOM, National Health Research Institutes Internal Medicine, Kaohsiung Medical Molecular Medicine, National Tsing Hua Department of Microbiology, Kaohsiung Medical AS-105-TP-B07 The regulatory mechanism of Dmc1-mediated recombination in meiosis (1)Ting-Fang Wang Molecular B07-1 Deciphering the molecular property of Dmc1 and Rad51 recombinases and their functional interaction in meiosis (2) Hung Yuan (Peter) Chi Biochemical Sciences, National Taiwan B07-2 Single-molecule analysis of the functional mechanism of Dmc1 recombinases B07-3 Defining in vivo interactions of Dmc1 and Rad51 recombinasomes on double strand break ends in budding yeast meiosis (2) Hung-Wen Li Department of Chemistry, National Taiwan (2) Ting-Fang Wang Molecular AS-105-TP-B08 The roles of galectins and C-type lectin receptors in anti-fungal and anti-bacterial immunity (1)Fu-Tong Liu Biomedical Sciences, B08-1 Interactions between galectins and B cells in defense against fungal infection (2) Kuo-I Lin (4) Kay-Hooi Khoo Genomics Research Biological B08-2 (2) Fu-Tong Liu 5

6 Galectins and dendritic cells in host defense against fungal pathogens (3) Chen Huan Yuan Biomedical Sciences, Biomedical Sciences, B08-3 Regulation of neutrophil functions by galectin-3 in host defense against candidiasis B08-4 Syk-coupled C-type Lecin CLEC5A in Pathogen-Induced NETs Formation and Host Defense against Pathogen Invasion (2) Betty A. Wu-Hsieh Graduate Immunology, (2) Shie-Liang Hsieh Genomics Research C. Division of Humanities and Social Sciences: (3 projects) Project No. Title of Thematic Project AS-105-TP-C01 Modernity Reconsidered: An East Asian View on Theoretical Genealogies and Historical Comparisons C01-1 East Asia and Modernity: A Rewriting of the History of the Modern World from the Perspective of Functional Differentiation C01-2 Citizenship, Professionalism and Modernity: Revisiting the Conceptions of Citizen between West European and Modern China from the Perspective of Functional Differentiation C01-3 A study of the transformation of East Asian modernity in terms of governmentality: the history of Taiwan under Qing imperial rule and Japanese imperial rule 6 (1) Project Director (2) Sub-project PI (3) Co-PI (4) Associate PI (1)Chih-Chieh Tang (3) Wei-Hsian Chi (4) Wen-Kai Lin (4) Michelle Fei-Yu Hsieh (2)Chih-Chieh Tang Institution Taiwan History, Academia (2) Tsu-Bang Chent Department of Fo Guang (3) Po-Fang Tsai Graduate Humanities in Medicine, Taipei Medical (2) Wen-Kai Lin Taiwan History, Academia

7 C01-4 Modernity and Governing the Economy: The Double Reflections on the Modes of Development in the West and Taiwan C01-5 The Religious Governmentality in Modern Society: A Study of Religious Modernity Based on the Change of Folk religion AS-105-TP-C02 To optimize mental capital and well-being in children and elders through brain science technologies and intervention C02-1 Integration of Visual and Audio Information for Hearing Assistive Framework and Application in the Assessment and Intervention in Speech-Language Therapy and Aural Rehabilitation C02-2 Age-related Development and Decline in Cognitive Control and Attention C02-3 Remembering the past and planning the future in older adults everyday life: the evaluation of prospective memory function in the elderly and its training C02-4 Using ERPs and Eye-tracking to investigate how executive function contributes to reading comprehension and the effectiveness of cognitive training AS-105-TP-C04 Re-thinking colonial medicine its nature and definition C04-1 Western Medicine and Public Health in the Nineteenth-Century Shanghai (2) Michelle Fei-Yu Hsieh (2) Wei-Hsian Chi (1)Chia-Ying Lee Linguistics, (3) Chao-Lin Liu Department of Computer Science, National Chengchi (2) Yu Tsao Research Center for Information Technology Innovation, (3) Hsiu-Wen Chang Department of Audiology and Speech Language Pathology, Mackay Medical College (2) Chi-Hung Juan The Cognitive Neuroscience, National Central (2) Shih-Kuen Cheng The Cognitive Neuroscience, National Central (3) Chia-Ying Lee Linguistics, (2) Chia-Ying Lee Linguistics, (3) Jie-Li Tsai Department of Psychology, National Chengchi (3) Ming-Tao Yang Pediatrics Department, Far Eastern Memorial Hospital (1)Shi-Yung Liu Research Center for Humanities and Social Sciences, (2) Shang-Jen Li History and Philology, 7

8 English Settlement C04-2 Westerners and Chinese Mental and Nervous Disease in the Late Nineteenth and Early Twentieth Centuries C04-3 Cold War Medicine in East Asia C04-4 Law, Public Health and Governmentality in Late Nineteenthand Early Twentieth- Century British Colonial Hong Kong C04-5 From the Colonial to the Postcolonial: The Psychiatric Career of a Colonial Psychiatrist (2) Wen-Ji Wang Science, Technology and Society, National Yang Ming (2)Shi-Yung Liu Research Center for Humanities and Social Sciences, (2) Chih-Hsing Ho European and American Studies, Academia (2) Yu-Chuan Wu History and Philology, 8