SAS GRID Assesments from d-wise

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1 SAS GRID Assessments Optimize Clinical Trial Processes and Maximize Your SAS Investment Get an unbiased assessment and plan for deploying SAS GRID SASGRID Assessmentskww.pdf 1 5/28/14 11:45 AM

2 2 SAS GRID Assesments from d-wise About d-wise d-wise Technologies, Inc. is a technology leader with the expertise to empower world-class life science and healthcare organizations to resolve their business optimization challenges, helping them rapidly harness and leverage data, systems and processes to gain competitive advantage. As one of North Carolinas' fastest growing companies, with offices in the US in Research Triangle Park area of Raleigh, NC and in the UK in Marlborough, England, d-wise offers product, service and consulting solutions that help clients clearly understand technology options, interconnect manual, disparate and point systems and implement best practices for robust, reliable, and compliant infrastructures that optimize data flow and business process. d-wise s ten year history of tailoring solutions to meet individual client needs as well as delivering data integration, data warehousing and standards solutions within highly-regulated industries is rooted in extensive domain knowledge of SAS software, clinical drug development and clinical data standards like CDISC. d-wise solutions for clinical trial optimization, metadata management and clinical standards provide a solid foundation for extracting accurate business analytics to enable critical business decisions to be made rapidly and based on all the data. Within the healthcare arena, d-wise provides data optimization for actuarial, quality, medical-management, and operational data marts and data warehouses as well as support for fraud detection using data-driven and repeatable processes.

3 3 SAS GRID Assesments from d-wise What Is SAS Grid Computing? SAS Grid Computing lets you create a managed, shared environment for processing large volumes of data and analytic programs quickly, using dynamic, resource-based load balancing. You can split individual SAS jobs and run each piece in parallel across multiple symmetric multiprocessing (SMP) machines using shared physical storage. This enables IT to build and manage a lower-cost, flexible infrastructure that can scale to meet rapidly changing computing requirements. What Can SAS Grid Computing Do for You? 1. Manage jobs and users more efficiently. Central administration helps you monitor and manage multiple users and applications under a given set of constraints. IT can meet service-level demands by easily reassigning computing resources to manage peak workloads and changing business needs. 2. Avoid user or source disruptions. Multiple servers in a grid environment enable jobs to run on the best available resource. If a server fails, you can transition its jobs seamlessly to other servers providing a highly available business analytics environment. 3. Enhance IT performance. Multiprocessing capabilities let you divide individual jobs into subtasks that are run in parallel on the best-available hardware resource in a grid environment. Faster processing of data integration, reporting and analytical jobs speeds decision making across the enterprise. How Is SAS Grid Computing Different? 1. Faster, better business decision making. SAS Grid Computing combines proven, industry-leading computing middleware from Platform Computing with the power of SAS Analytics to scale business processes and accelerate decisions for greater competitive advantage. 2. More efficient big data and analytic processing. SAS solutions for data management, predictive analytics and reporting automatically submit jobs to a centrally managed grid of shared computing resources, enabling big data and complex analytics to run faster and continuously. 3. A cost-effective processing environment. Grid computing enables IT to add low-cost commodity hardware resources incrementally without disruption to the organization, which eliminates the need to size today's environment for your future needs.

4 4 SAS GRID Assesments from d-wise As life science organizations' use of business analytics grows, so does the need for a flexible IT infrastructure one that can scale cost-effectively, meet peak demands and manage growing, increasingly diverse user workloads. SAS Grid Manager delivers grid computing capabilities, enabling organizations to create a managed, shared environment for processing large volumes of data and analytic programs. Benefits of SAS GRID within Pharma 1. Meet changing business demands with dynamic workload balancing. SAS Grid Manager gives IT greater flexibility to meet service level commitments by easily reassigning computing resources to meet peak workloads or changing business demands. The solution provides a central point of control for administering policies, programs, queues and job prioritization across multiple types of users and applications to achieve business goals under a given set of constraints. 2. Create a highly available SAS grid computing environment. Having multiple servers in a grid environment enables jobs to run on the best available resource. If a server fails, its jobs can be transitioned seamlessly to another server providing high availability. In addition, IT staff can perform maintenance on specific servers without interrupting analytics jobs, as well as introduce additional computing resources without disrupting the business. 3. Get faster results from your existing IT infrastructure. Multiprocessing capabilities let you divide individual jobs into subtasks that are run in parallel on the best available hardware resource. The SAS programs best-suited for parallel processing are those with large data sets and long run times, as well as those with replicate runs of independent tasks running against large data sets. Processing data integration, reporting and analytical jobs faster accelerates decision making across the enterprise. 4. Grow computing resources incrementally and cost-effectively. SAS Grid Manager lets you fully utilize all available computing resources now, and cost-effectively scale out as needed, adding capacity in single-processing units to keep IT spending in check. Because you can add low-cost commodity hardware resources incrementally, there's no need to size today's environment for what you anticipate your needs will be a few years from now. 5. Eliminate bottlenecks within SAS Programming Environments. SAS Grid Manager allows organizations to eliminate performance bottlenecks within statistical computing environments and effectively address areas of under utilization by providing an administrative dashboard that gives you the ability to distribute workload across a grid or cluster and obtain results that otherwise may not be possible, even given today s processor speeds. 6. Manage the complications of systems integration from Mergers and Acquisitions SAS Grid Manager allows organizations to easily manage data and systems acquired during mergers and acquisitions and across contract research organizations, without affecting existing workflows.

5 SAS GRID Assesments from d-wise d-wise's SAS GRID Assessment d-wise Business and Technology Architects will partner with your IT and business stakeholders to understand your requirements and leverage our extensive domain knowledge of architecture, SAS software, and clinical and statistical programming so you will be able to maximize your investment in SAS Grid technology. Our team will take you through a defined and proven methodology that delivers all the information you'll need to present a compelling business case for moving to SAS Grid. SAS Grid computing is extremely useful where IT departments need to manage complex infrastructures consisting of a conglomeration of disparate hardware and user requirements. In Life Sciences today, this situation is often exacerbated by mergers and acquisitions. Additionally, it offers an alternative to purchasing new, larger server platforms. With SAS GRID, you'll be able to harness all the computing power of a network of servers, manage workloads, make use of existing hardware, eliminate the need to purchase new larger servers. By doing so, Life Science organizations will be able to manage risk, improve business processes and control IT costs. Our Assessment Process NEEDS ANALYSIS - Prior to meeting with your team, d-wise will conduct an in-depth interview with key stakeholders to learn more about your existing infrastructure and objectives. Information on existing SAS systems, capacity and architecture will form the foundation for us to prepare for our initial discussions and identify key issues of implementing SAS GRID in your organization.

6 6 SAS GRID Assesments from d-wise KICK-OFF MEETING - With the information we uncover during our initial needs analysis combined with d-wise domain expertise, the KIck-off meeting will gather key stakeholders and business leads to address the following topics: 1. Capacity within your existing environment 2. The indicative sizing for the sugessted architecture 3. The expected growth of users, data and analytical complexity 4. Software and solution stack to reflect your current as well as future requirements 5. Definition of a Project Roadmap that could make us eof the new SAS GRID platform 6. Definition of what current business processes need to integrate or map to the new environment 7. Definition of the Storage Strategy 8. How your current IT Infrastructure strategy integrates with the proposed future SAS GRID architecture RESEARCH CONSOLIDATION DOCUMENTATION - After the Kick Off Meeting, d-wise Consultants and subject matter experts will conduct a thourough investigation to research and validate the findings uncovered, and identify any areas of concern. Any issues identified will be discussed with your stakeholders and business leads to clarify any issues. d-wise will compile an extensive assessment document for review by all concerned and execute any updates, additions or ommissions as required by your stakeholders. IT/BUSINESS GROUP DISCUSSIONS - A final document will be produced, presented and reviewed in detail by the entire project team to insure completeness and build agreement that the plan meets the needs and objectives defined at the initiation of the assessment. SAS-BASED QUALITY REVIEW - Upon agreement that the assessment document meets the satisfaction of the entire project team, d-wise will collaborate with SAS quality experts to ensure that all expectaions can be achieved from a technology standpoint and that there is minimal risk with proceeding with implementation of a SAS GRID deployment. d-wise RECOMENDATION/PRESENTATION - Once the SAS-based quality review is completed, d-wise will present a completed assesssment document that outlines our findings and recommendations for implementing and maintaining an on-going SAS GRID instance. Additional information will include a recommended growth path and on-going data tier consolidation, troubleshooting and codebase monitoring and management. PRODUCTION PLAN-FINAL DOCUMENTATION - d-wise architects will deliver a FINAL completed document that presents the recommended architecture and the value it will bring to your organization. The document will contain a High-level SAS GRID architecture recomendation, an inventory of all required software upgrades, a comlete timeline with implementation milestones and a summarization of risks, issues and considerations and future opportunities. FORMAL PRESENTATION AND HAND-OFF - a final presentation of the Assessment and recommended production plan will be conducted by a SAS-certified technolgy architect, and will include information to assist you with building a business case. Also included will be a hardware and software investment appraisal and return on investment model.

7 SAS GRID Assesments from d-wise 7 The estimated time required to conduct the d-wise Assessment process is approximately 15 working days depending on the complexity of the assessment and your IT environment. Project duration may also vary according to the needs of your particular project, or if insufficient information was provided during the discovery stage. Price depends upon various factors: level of effort, required skills or expertise, market demands and business strategy. Contact your SAS Account Manager to determine and confirm the estimated price and duration of this service, and for more information about related services. All travel and expenses are additional. We view grid computing as a way to harness all of the computing power available from a network of computers. SAS technology gives you the ability to distribute workload across a grid or cluster and obtain results that otherwise may not be possible, even given today s processor speeds. Combining SAS technology with grid computing enables you to: 1. Add additional groups of processors (grid nodes) when required, rather than commission and migrate users to new servers. 2. Incorporate existing hardware, such as current production and disaster recovery environments, into the grid 3. Ring fence nodes, or groups of nodes, for specific departments or tasks 4. Dynamically reallocate nodes to meet peaks in demand).

8 US Headquarters: 1500 Perimeter Park Dr. Suite 150 Morrisville, NC Main Phone: (919) :00AM-5:00PM EST SASGRID ImplementationskwwB.pdf 8 UK Office: Suite 2, 3rd Floor 61 Mosley Street Manchester, M2 3HZ United Kingdom UK Phone: +44 (0) /28/14 10:40 AM