THE POWER OF ONE SMART SOLUTION. Imagine one partner for all your automation needs. Meet the leaders in automation.

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1 THE POWER OF ONE SMART SOLUTION Imagine one partner for all your automation needs. Meet the leaders in automation.

2 Beckman Coulter Laboratory Support SEE WHAT THE LEADER IN LABORATORY AUTOMATION CAN DO FOR YOUR MICROBIOLOGY LAB. Experience you can trust. Beckman Coulter is a leader in track-based laboratory automation, we now bring this trackbased automation expertise to the microbiology laboratory, making us the only provider of automation solutions for the entire central laboratory. The power of our Smart Microbiology Automation Solution is in the complete package we provide, with expert consultations, best-in-class innovative and accurate technologies, and award-winning service support. Our solution fully automates the labor-intensive pre-analytical, analytical, and post-analytical tasks in the microbiology workflow to save you time and reduce costs. The Beckman Coulter Smart Microbiology Automation Solution. Full automation, from pre-analytical to post-analytical data management Expert consultation from the leaders in automation Best-in-class innovative products Strong partners Flexible solutions that grow with your lab Award-winning support service, from implementation throughout the life of the instrument Get It Right With our Award-Winning Support Team

3 Meet your Lean automation team! Whether you are embarking on a microbiology lab expansion or creating a laboratory from the ground up, it requires making a long series of the right decisions. And making the right decisions ends with installing the right solutions. Our global Microbiology Consulting Solutions, associated with Beckman Coulter s Performance Improvement Team, is available to do a thorough analysis of your lab to assess your current and future workload demands. They can help you design the right combination of best-in-class microbiology automation solutions solutions that will save you time and reduce costs while delivering timely, accurate results. Count on our team of Lean certified microbiology workflow consultants to help identify new opportunities that streamline your laboratory s operations: Identify your key issues, challenges, and work flow opportunities. Evaluate the best possible solutions by utilizing on-site observations, data-driven analyses, and robust simulation tools, including ROI and financial justification. Design customized solutions based on best demonstrated practices and industry benchmarks to meet your current needs and future vision. Get support every step of the way and way beyond. After the installation, our Microbiology Consulting Solutions team is available when needed. If you find workflow demands increasing or staffing decreasing, they ll help you get back to the workflow output you expect. Our global installed base relies on our Microbiology Consulting Solutions Improvement Team and technical application specialists to help enhance efficiencies and provide workflow solutions or repairs when needed. Experienced technical application specialists work with your staff to ensure successful implementation during the initial installation and beyond. Beckman Coulter s dedicated microbiology service engineers are strategically located to provide rapid response to your needs. Post-installation optimization and kaizen events help you evaluate new processes, incorporate new technology into your work-flow, and explore new opportunities for improvement. Learn about our innovative training and education. Smart. Beckman Coulter has developed standardized processes, tools, education, and programs designed to maximize your experience with our products. Beckman Coulter s Blended Learning Approach includes instructor led training, web-based training and training tools designed to provide continual on-going training support to increase staff competency, efficiency and productivity. On-site, hands-on training ensures that the entire staff has an effective learning experience with new systems. Special advanced training for key operators is available for some systems. I would tell any executive if you re going to go down this path find partners that are really in the game with you and are willing to commit the same level of energy and resources to make it a success. Sam Terese, CEO and President, PCL Alverno

4 Smart Microbiology Automation Solution AUTOMATE YOUR MICROBIOLOGY LABORATORY EVERY STEP OF THE WAY AND WAY BEYOND. The Smart Microbiology Automation Solution easily expands to meet your current and future workflow demands. With more than 30 years of ID/AST testing expertise, strong strategic partnerships, and a leadership role in track-based automation, we are able to offer a smart microbiology solution with best-in-class products. Our solution automates and integrates the pre-analytical, analytical, and post-analytical steps in the microbiology laboratory, improving productivity, streamlining workflow, and providing accurate results for the clinician ultimately improving patient care. Informatics Post-Analytical Pre-Analytical Analytical Post-Analytical Specimen Processing Copan WASP: Walk-Away Specimen Processor 1 Automates all the core aspects of microbiology specimen processing, even for challenging sample types. Standardizes streaking to ensure superior isolation, eliminating variability between technologists. Modular design allows future additions of features, such as automated conveyor tracks. Digital Microbiology Copan WASPLab 2 Automates routine manual activities, such as plate transportation, sorting, and matching. Robotic incubators provide optimal environmental conditions to support more robust growth. Streamlines culture analysis and resulting with a combination of sophisticated software and high-resolution imaging technology. ID/AST and Rapid ID MicroScan WalkAway plus Microbiology System 3 Delivers gold-standard accuracy for microorganism identification and susceptibility testing. Enables simultaneous processing of conventional, rapid, and specialty panels on a single, automated platform. Delivers accurate emergingresistance detection for the most challenging pathogens, including CRE, ESBL, MRSA, VRSA, VRE, and PRSP. Bruker MALDI Biotyper System 4 Rapid identification of organisms provides critical information to clinicians. Cost-effective, highly accurate and applicable to a wide range of microorganisms. Provides a seamless Lean workflow with the MicroScan WalkAway plus system. Informatics Information Management Systems 5 The LabPro Software Suite provides powerful data management of microbiology laboratory test results, from order to LIS transmission, increasing efficiency in busy and complex laboratories. Integrated LabPro AlertEX software contains an extensive database of predefined rules recommended by microbiology leaders and is fully customizable to support local and changing needs. Customizable middleware solutions provide connectivity and data- management options to meet the needs of every laboratory. 5

5 Pre-Analytical Analytical Post-Analytical Specimen Processing Pre-Analytical ID/AST and Rapid ID Analytical Through the years, we ve partnered with MicroScan, and they ve done a very good job to come in and do assessments for our laboratory, not only in design but also in workflow and how we operate. MicroScan has done a very nice job to partner with us, to listen to the voice of the customer and work with us to adapt the solutions to what will fit our needs. And that s been a real plus. Dale Kahn, M.T. (ASCP), Central Laboratory Operations Director, Alverno Clinical Laboratories

6 Specimen Processing OPTIMIZE YOUR MICROBIOLOGY LAB WORKFLOW WITH THE COPAN WASP: WALK-AWAY SPECIMEN PROCESSOR AND WASPLAB SYSTEM. The first step in building your Microbiology Automation Solution is to be sure it requires the fewest steps to operate. Microbiology labs face many challenges. Among them is the need to balance budget constraints with fewer skilled technologists and increased workloads. The Copan WASP Specimen Processor and WASPLab System are innovative technologies that help microbiology labs meet these challenges. The WASPLab system incorporates a sophisticated, bar-code-driven specimen processor with automated incubation and imaging, freeing technologists from labor-intensive manual tasks and allowing them to focus on the high-complexity work for which they were trained. These systems streamline functions, allowing for increased capacity and faster reporting. Copan WASP: Walk-Away Specimen Processor The Copan WASP System automates all the core aspects of microbiology specimen processing: Planting and streaking Gram stain slide preparation Enrichment broth inoculation Modular design allows you to add the newest technologies when you need them. Standardized robotic streaking with classic microbiology streak patterns improves isolation. Customization of system and protocols streamlines the workflow. Internal camera and SmartScan bar-code technology ensure confidence in results. Copan WASPLab System The Copan WASPLab System combines robust pre-analytical WASP System processing with high-resolution imaging and robotic incubation, connected by a customizable, bar-code-driven conveyor track. Smart Incubators provide: Robotic plate management High-resolution imaging, including time zero image Controlled environment to support faster, more robust growth High resolution digital imaging acquisition camera provides 27 megapixel images under a variety of lighting options with no distortion. Copan WASPLab Software Web-based WASPLab software supports: Flexible workflow management Streamlined reading and resulting of cultures Quicker availability of valuable clinical results

7 Pre-Analytical Analytical Post-Analytical 4 1 Copan WASPLab Components 1 WASP: Walk-Away Specimen Processor 2 Smart Incubator and Imaging Camera (Single: 854 Plates; Double:1708 Plates) 3 Custom Track System 4 Image Acquisition Station The installation of the WASPLab has changed my work day as the system can cover part of my daily tasks and give me more free time for other activities. Thanks to the image analysis we can easily read the plate and report results quickly, without several manual steps. The most beneficial feature is the digital plate reading clear and quick. Milva Ombretta Bertazzolo, WASPLab Operator, Niguarda Hospital, Milan, Italy

8 ID/AST and Rapid ID SPEED MEETS ACCURACY WITH THE MICROSCAN MICROBIOLOGY AND BRUKER MALDI BIOTYPER SYSTEMS. Discover the winning combination of accurate AST and rapid ID with the MicroScan Microbiology and Bruker MALDI Biotyper Systems. When it comes to microbiology results, you need answers right the first time. MicroScan Microbiology Systems detect resistance other systems may miss ensuring accurate detection of emerging and low-level resistance with direct, growth-based ASTs. And the Bruker MALDI Biotyper System delivers fast, accurate identification of isolates. When combined, these best-in-class technologies provide enhanced workflow efficiencies and ultimately improve patient care. MicroScan WalkAway plus Microbiology Systems MicroScan Microbiology Systems provide a true growth-based ID/AST system for microorganism identification and susceptibility testing. These systems provide high-quality performance, reliability, and unmatched expertise for laboratories of every size. Quality Trusted Worldwide Gold-standard accuracy for microorganism identification and susceptibility testing. Supports multiple workload needs with 40- and 96-panel-capacity models. Includes automated incubation, test interpretation, and reagent control. MicroScan Panels Resistance Detection Done Right Detect emerging resistance as it occurs with direct MIC technology. Manage changing formulary needs with a broad antimicrobic menu. Select ID-only, AST-only, and ID/AST combination panels for workflow flexibility. Fewest FDA limitations 1 of the major automation systems. Broad choice of panel formats, including conventional, rapid, ES L plus, MICroSTREP plus, and specialty ID panels. Bruker MALDI Biotyper System The Bruker MALDI Biotyper System uses MALDI-TOF technology which is highly accurate and applicable to a wide range of microorganisms. This cost-effective system is much faster than traditional methods and provides the ideal complement to the MicroScan WalkAway plus System. Make Every Minute Count Gold-standard MALDI-TOF technology provides rapid identification of isolates. Supports antibiotic stewardship allowing physicians to better manage treatment. Streamlined Lean workflow for maximum productivity. Highest throughput 144 identifications per hour. Flexible Options on Demand The single, open, and comprehensive database saves time and streamlines workflow. Target plates are available in a variety of sizes, ranging from 24 to 96 wells. Options include disposable, resuable, and BigAnchorChip target plates for liquid samples. 2 Compact, ergonomic, and environmentally friendly, the small footprint fits easily into the most space-constrained labs.

9 Pre-Analytical Analytical Post-Analytical First-Time Accuracy The MicroScan conventional panels use a growth-based, non-id dependent direct testing method, which provides optimal detection of emerging resistance. The system does not rely on historical data: it provides a real-time advantage for accuracy and uses direct MIC* technology to detect emerging and low-level resistance. This means fewer confirmatory tests are needed, providing you with accurate results the first time. The MicroScan unit is an overnight testing system that is a true growth/no growth system, which gives you the most accurate results. It offers the flexibility of either a full MicroScan MIC panel or combination identification and susceptibility panel. The MicroScan [system] has been very consistent and reliable; it s attested by the fact that we have 10 of them. James Clark, M.T. (ASCP), Microbiology Manager, Alverno Clinical Laboratories *Minimum inhibitory concentration.

10 Informatics GET CONNECTED. STAY CONNECTED WITH SOFTWARE SOLUTIONS FOR EVERY NEED. Make accurate results actionable. Our worldwide customer base agrees: LabPro Software Suite with LabPro AlertEX and LabPro Connect improves workflow. As labs expand, data management becomes increasingly important. Our middleware solutions provide options for laboratories of all sizes, and the enhanced data management they deliver ultimately leads to faster results reporting and improved patient care. LabPro Software Suite LabPro Information Manager Creates customized reports. Manages results from order entry to LIS transmission. Easy-to-use software works for all LabPro products. LabPro AlertEX Provides automated detection of atypical results for quick reporting. Allows use of alternate breakpoints when interpreting MIC results. Directs staff to the most appropriate action based on customized institutional procedures. LabPro Connect Allows management of MicroScan results without leaving reading station. Consolidates data from multiple MicroScan systems anywhere. Save time by eliminating non-value-added movement. Middleware Essentials Collects and transfers data to/from multiple types of instruments. Maximizes traceability and quality. Improves productivity by streamlining workflow. Keep Your Lab Productive With the Right Connections Get the Power of One Smart Solution. The Beckman Coulter Smart Microbiology Automation Solution provides best-in-class accuracy with industry-leading automation technology to improve your lab s performance, from pre-analytical to post-analytical data management. The power of our solution is the complete package we provide, from laboratory assessment through installation and beyond. Beckman Coulter is a partner you can count on. Make the smart choice. Contact your Beckman Coulter representative today.

11 Pre-Analytical Analytical Post-Analytical Middleware Essentials Choose from a variety of middleware options to fit your connectivity needs. LabPro Connect Manage MicroScan results and data from any computer workstation to LIS. Everyone can access LabPro from their own computer. Much smoother, so no more waiting in line or congestion. When doctors call for results, we re able to minimize screens, click on the LabPro/WA monitor, click a chicklet and give results. Any bench can look up another bench s results, create Alert rules and drug suppressions, and I can run epi from my office. Before, I had to wait until the end of day. Violet Rekasius, Tehnical Specialist, Loyola University Laboratory

12 References 1. Refers to conventional overnight panels. 2. MALDI Biotyper CA system is the FDA-cleared system for gram-negative bacterial colonies cultured from human specimens. Bruker 48 spot steel target plates are FDA-cleared. BigAnchorChip is for research use only. Not all products available in all countries. Beckman Coulter, the stylized logo, MicroScan, MicroScan plus, MICroSTREP plus and WalkAway are trademarks of Beckman Coulter, Inc. and are registered in the USPTO. Lab Forward, LabPro and Alert Ex are trademarks of Beckman Coulter, Inc. WASP, WASPLab, the Wasp Logo and WASP Walk Away Specimen Processor are registered trademarks or trademarks of Copan Italia SpA. MALDI Biotyper and BigAnchorChip are the property of Bruker Daltronik GmbH. All other trademarks are the property of their respective owners. For Beckman Coulter s worldwide office locations and phone numbers, please visit BR-18578A B Beckman Coulter, Inc.