Introduction to Kalabie Electronic Lab Notebook. May 2009

Transcription

1 Introduction to Kalabie Electronic Lab Notebook May 2009

2 Kalabie ELN: part of the integrated Agilent solution Multiple inputs Data coming from instruments and other documents/ information used to document research (input) ICP-MS LC UV-vis GC/MS GC LC/MS Lab-on-a Chip CE LIMS ELN PDF Legacy Data MS Office Images Drawings Research Other Applications (LIMS, inventories, etc.) Knowledge Data Experiments and Insights Data Storage and Organization Scientific Data Generators Support and Professional Services Kalabie ELN Electronic Laboratory Notebook OpenLAB ECM Enterprise Content Management Specialized Software CDS/ICM/GeneSpring/EZChrom Chemstation/MassHunter Third Party Chromelion, Empower, TotalChrom From data to knowledge, Agilent Technologies helps laboratory managers and directors reduce the time, effort, and cost to go from raw data to final insight. Page 2

3 Kalabie ELN: Front End and Focal Point Collaborate Inform Research Processes ELN Research Management Support/Share Chemistry Biology Analytics Research Activities Kalabie ELN is an environment that supports your work and provides a central repository of information across activities and disciplines, so colleagues and scientists across the organization can view results and share work in a collaborative effort. Kalabie ELN can mine information that provides insight across labs and is 21 CFR part 11 compliant. Page 3

4 What is Kalabie ELN? Kalabie is a web-based ELN which enables you to Increase productivity Easily document and manage experiments Support multiple disciplines with a single solution Reduce cycle times with request workflow Integrate with existing Information Systems Accommodate for special requirements by extensibility at various levels Protect Intellectual Property Page 4

5 Improve efficiency, access to data and IP protection Kalabie ELN centralizes and secures all data from experimental work with the high level of traceability we required Dr. Ailie McCabe, Development Manger, e2v Biosensors 21CFRpart11 compliant electronic signature and audit trail Fully configurable sign and witness workflow Set reminders, automatically SAFE BioPharma digital signature compliant Page 5

6 Improved research efficiency for three sites, in three countries "Compound registrations increased 15 % versus the year before." Hans Troost, Business Analyst, Solvay Pharmaceuticals Increase personal productivity Easily check pending experiments, experiments to sign or pending requests Browse my experiments, create favorites based on search criteria QuickSearch across experiments and documents Register and search molecule and reactions Page 6

7 For the synthetic chemists Plan and design reactions using standard chemistry tools ChemAxon bundled Integrate with Symyx, Accelrys and ChemDraw Seamless integration with existing registration systems and sourcing databases Create favorites for commonly used reagents and solvents Quick experiment setup with standard sentences and templates Create batches, split samples and submit for analysis directly from the experiment Reduce redundant experiments; search across reactions and molecules Page 7

8 For analytical chemists Reduce cycle time from request to result with Request Workflow Check work lists, queue requests Direct link to related experiments for easy tracking of procedures and details Reduce time for routing document approval Smart Import directly from instruments ChemStation, ACAML, ANiML Excel templates for further analysis Capture images, chromatograms, spectra; fully searchable annotations Save time creating experiments using Dynamic Forms Create pick-lists, checkboxes and data entry templates Page 8

9 For the biologist and other disciplines Rich text environment for free-form data entry Control font, type, style Create tables, embed Excel, Word, PowerPoint Insert images, searchable annotations Quickly create experiments using standard sentences or paragraphs Insert one or more Dynamic Forms Use pick-lists, checkboxes, calculations, Excel templates (including macros and graphics) Clone previous experiments Full audit trail, signature workflow Link to external sources, import data and results, drag and drop files into an experiment Page 9

10 Kalabie ELN Top three benefits 1. Expedite decision making Smart Import: Automatically import data from ChemStation Integration with OpenLab ECM Direct access to results and documents 2. Decrease cycle time Analytical Request Workflow Manage electronic requests, create sample lists and queue work for analytical chemists extracted from raw data are inserted into an Excel sheet 3. Increase collaboration Dynamic Forms Flexible environment where users can design their own data entry templates QuickSearch Quickly find results, procedures and experimental details using Google-like searching Page 10

11 Expedite decision making Increase productivity: Reduce cycle time from experiment to result Smart Import Fast import of XML and ChemStation files (ACAMAL, AniML) into predefined Excel templates Run additional calculations such as correction factors, purity determination Use all the functionality in Excel including graphics Results, documents all stored with the experiment for quick search and retrieval extracted from raw data are inserted into an Excel sheet Integration with OpenLab ECM: Automation of document storage into central repository Direct secure link from Kalabie ELN to OpenLab ECM Quick search to find results and raw data Any file uploaded into OpenLab ECM accessible in Kalabie ELN: ChemStation, EZChrome, Empower Page 11

12 Decrease cycle time Increase efficiency: Reduce time from analysis request to result and final insight Analytical Request Workflow: Increase communication between working groups Submit and queue requests for samples to be tested or assays to be run Scientist can quickly review request queue, select work and create experiments Once finished experimental results are automatically linked to the originating experiment Page 12

13 Global environment for chemists and analysts Batch selection Sample creation Page 13 Link to the request Status of the request Link to the analysis to drill down to analysis Details and raw data

14 Environment for analytical work Page 14

15 Global environment for biologists and quality control Same link as before to analysis requests Page 15

16 Increase collaboration Increase efficiency: Capture all results in context of the experiment for easy searching and traceability. Dynamic Forms: Create specific user templates for any user and any experiment type to easily collect all relevant details Right click and add form to any experiment Search experimental details and results within the experiment, documents and image annotations Quickly find what you need when you need it Google-like searches with QuickSearch Clone experiments for quick setup of routine experiments Share data and results; reduce repeat experiment and expedite knowledge transfer for new experiments Page 16

17 How do dynamic forms work? Create re-usable fields and forms Permissions can be set by user or group Users can only enter data in certain fields Fields can be made mandatory Users can be allowed to add additional fields from a set selection The forms repository is controlled by a power-user or admin to ensure data integrity Forms can be used as results data entry, protocol information and include calculations All forms and information collected in a form are searchable Access restricted to power users Defines access/edit rules for forms Page 17

18 Extensions through scripts to provide calculations and integration Page 18

19 Summary Kalabie ELN is a web-based solution which provides a central repository of experimental information across disciplines which enables organizations to: Increase productivity Easily document and manage experiments Share work in a collaborative effort Support multiple disciplines with a single solution Reduce cycle times with request workflow Integrate with existing Information Systems Accommodate for special requirements by extensibility at various levels Protect Intellectual Property Page 19

20 Questions Page 20