Innomed Medical Inc. development for healthcare. Ákos Horváth. Senior Project Manager Image Processing Department of X-Ray Systems

Transcription

1 Innomed Medical Inc. development for healthcare Ákos Horváth Senior Project Manager Image Processing Department of X-Ray Systems

2 Table of contents Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Short introduction of Innomed Medical s development Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance systems Premises Turnover

3 Innomed history Established in 1989 by ten R&D engineers First success with the ECG portfolio Domestic market leader in cardiology sector since 1993 Own developed x-ray generators since 1994 Investment in new product lines: bedside monitor development Acquisition of the Danish Artema defibrillator factory in 2002 Nowadays: Dealers in more than 110 countries Over 135 employees 10 million Euro annual turnover

4 Main competences Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Developing medical devices Manufacturing Integrating x-ray systems Customised mobile screening units Marketing Participation in tender projects Turn-key hospital projects

5 Product range Cardiology Diagnostic ECGs: ECG devices Data base management sw Holter ECGs Stress test systems Patient monitoring Clinical defibrillators Radiology X-ray generators Mobile X-ray unit Integrating complete systems Digital imaging system PACS system Chest CAD system Veterinary

6 Electrocardiographs Wide range of devices Small, portable devices for GP s Clinical versions Exercise system with threadmill or bicycle ergometer Cardiological data management system Holter ECGs

7 Defibrillators Devices for clinical use Biphasic defibrillating waveform Cardioversion Semi automatic mode External pacemaker Measured parameters: 12channel ECG NIBP SPO 2 CO 2

8 Monitor systems Bedside monitor for intensive care unit Portable 7 lightweight monitor with wide range of functionality Small wireless monitor for hospital and home care Central monitor: monitoring and controlling the network-connected bedside monitors Wireless communication between the measuring head and the monitor If needed stores all parameters for days

9 Radiological devices High frequency X-ray generators Complete digital X-ray systems DR, CR systems Radiation protected cabin High throughput, with low dose User friendly software with PACS integration Built in chest X-RAY station - mobile application

10 MRX Tel Radiological devices TOP-X DR TSm TOP-X 100 MS

11 PI-PACS

12 Early detection of lung cancer PI-PACS Chest CAD 1 system on chest X-ray Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Innomed Medical Inc. in cooperation with the largest technical and medical universities in Hungary: Budapest University of Technology and Economics and Semmelweis University developed the PI-PACS Chest CAD, a Computer Aided Detection System for Chest X-Ray images, between Our goal was to develop a chest CAD system that helps a skilled pulmonologist or radiologist raise his/her sensitivity in lung disease detection especially tumorous ones. 1 CAD Computer Aided Detection System that is a decision support system

13 PI-PACS Chest CAD Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Soft tissue analysing: Bone shadow eliminating algorithms make the lung tissue visible The developed algorithms using artificial intelligence are the followings: Find circular like dens areas Find blurred and infiltrated areas The tool after a complex preprocessing uses three different filters: Small circular shadows (5-35 mm) Large circular shadows (35-75 mm) Infiltrated areas of different sizes The findings of Chest CAD are shown for the pulmonologist. We use their suspected borderline as mark signs.

14 PI-PACS Chest CAD Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover

15 Digital Tomosynthesis (DTS) Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Chest radiography (CXR) Fundamental examination in lung imaging Short examination time Easy accessability Low cost Low radiation dose Disadvantages with CXR Limited sensitivity and specificity for many tasks 2D CT solves the problem Good enough sensitivity and specificity for Lung cancer Disadvantages with CT High radiation doses Chest CT: E~5 msv (low dose CT?) Chest x-ray (PA): E~10-20 µsv Complicated equipment Expensive examination For many hospitals: limited resource Delayed diagnostics 3D

16 Bridge the gap? CXR CT Extensive overlapping (2D) Extremely low dose No overlapping (3D) Relatively high dose

17 Digital Tomosynthesis (DTS) Modern version of conventional tomography A number of projections are acquired at a low dose - over a limited angular range - and used to reconstruct section images of the patient (=limited angle CT) J. T. Dobbins, H. P. McAdams: Chest tomosynthesis: Technical principles and clinical update in European Journal of Radiology 2009 pp

18 Image reconstruction Shift-and-add Back projection Filtered backprojection Fourier transform Ramp filter Low-pass filter Inverse Fourier transform Shift-and-add

19 Digital Tomosynthesis (DTS) Two main improvements from conventional tomography Reconstruction of arbitary number of slices from one acquisition Removal of surrounding anatomy Why today? Availability of suitable detectors (FPD) Computer power Radiation dose concerns

20 Digital Tomosynthesis (DTS) Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover

21 Detectability Visibility Vikgren et al, Radiology 2008;249:

22 Bridge the gap? Extensive overlapping (2D) E= msv Reading time 2 min Some overlapping (2.5 D) E= msv Reading time 5 min No overlapping (3D) E=0.5-5 msv Reading time 10 min

23 Quality assurance system Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover ISO 9001 ISO 13485:2003 CE marked products FDA, UL approved production FDA for our products: under process

24 Premises Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Head office: Budapest Management Financial department Export and domestic sales Customer service R & D department X-ray development ECG development Bedside monitor development Defibrillator development Training/guest centre: Apartments, training hall, sauna, swimming pool

25 Premises in Esztergom Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Factory: Esztergom Manufacturing X-ray generator ECG devices Defibrillators Bedside monitoring system Service support Factory of Medicor Diagnostics /member of Innomed Group/ Tilting tables

26 Turnover in Million EUR Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover Turnover from Domestic Sales Turnover from International Sales Total

27 Presence in 119 countries Content Innomed history Main competences Product range Electrocardiographs Defibrillators Monitor systems Radiological devices PI-PACS PI-PACS Chest CAD Digital Tomosynthesis Quality assurance sys. Premises Turnover

28 Thank You for your attention! Heal the world with Innomed! Welcome to visit us at Medica (Booth 9B48) November Düsseldorf