Paperless Manufacturing Solutions With MES PAS-X and OSIsoft's PI System For Bio Manufacturing
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1 Paperless Manufacturing Solutions With MES PAS-X and OSIsoft's PI System For Bio Manufacturing Presented by Barry Higgins, Janssen Biologics Robert Welter, Werum Software & Systems
2 Barry Higgins Manufacturing Systems Engineer Janssen Biologics, Ireland Robert Welter Head of Department PAS-X Product Management Werum Software & Systems AG 2
3 About Janssen 3 key business sectors: Consumer Medical Devices & Diagnostics Prescription Products JSC API Supply Chain Chemicals 6 sites Biologics 5 sites Worldwide Pharmaceutical sales of $24.5 billion in
4 Who we are 4
5 What we do Software Services Content 5
6 Set values Synchronization Overview ERP Material Master Overall Inventory Production Orders DMS SOP s Drawings Instructions CAPA Deviations LIMS Samples PAS X Master Batch Records Production Resource Management Electronic Batch Recording Material Management in Production From Weigh & Dispense to Packaging Review by Exception LDAP / AD Users PI System Process Control System(s) Process data Alarm & Events Building Automation System(s) Process data IPC instruments Scales & Printers 6
7 Electronic Batch Recording with PAS X Master Batch Records Electronic Batch Recording Approval Process Review by Exception 7
8 Integrated Approach PAS X Commands & Set Points to Process Control System Process Data, Alarm & Events collected in the OSIsoft PI System OSIsoft PI System data referenced in the PAS X EBR PAS X EBR batch execution data referenced in the PI System PAS X PI System Process Control System(s) Werum's PAS-X User Group Meeting Copyri 2012 g h t 2013 OSIso f t, LLC. 8
9 The Details PAS-X MBR PAS-X EBR Attributes of Equipment Classes & Equipment Tag 1: Tag 2: Tag 3: Value-Type Value-Type Value-Type Tag ID Tag ID Tag ID Actual values Alarms Events Tag 1: C Tag 2: 47 RPM Tag 3: 1.37 Bar Batch Interface BO: St 09:00 am BF: St 12:00 pm BF: Fi 01:00 pm PI AF PI System Trend data Events Batch data 9
10 Integrated Solution - Benefits PAS X PI System Seamless integration of process data into Master Batch Record definition and Electronic Batch Recording Handling of Alarm & Events according regulatory requirements Batch analysis at the EBR level Long-term archiving of process data Using industry standard MES and Historian Pro-active development of new features & functionality Predefined, configured and reliable integration 10
11 PAS X to PI Event Frames OSIsoft and Werum collaborated to develop the Werum PAS-X Batch Interface which will become standard OSIsoft product. This enables us to perform batch analysis at the EBR level from a Basic Operation (BO) or Basic Function (BF) perspective. The capability to store basic function activities as batch events is similar to current DCS batch events. Material and equipment usage data can be captured. Livepoint from Mirabo Systems 11
12 PI Asset Framework From PI AF to ebr PI AF Element Templates Class based template. Unit Elements created from template. Upload from PI AF Class based PCS MBR elements Building blocks for MBR modellers MBR Generation Class based MBR EBR Execution Unit resolved at run-time. Data retrieved from PI AF Unit Element 12
13 Removing Paper ph testing before PAS X & OSISoft PI: Paper Batch Record instructs technician to take ph sample. Technician manually checks Paper equipment logbooks. Technician takes sample and performs test and prints out result on paper. Technician copies result and attaches it to Batch Record and records result. Result in batch record, printout and copy are reviewed before batch release. 13
14 Removing Paper ph testing after PAS X & OSIsoft PI System: EBR prompts Technician to. Take ph sample. Technician scans ph meter for status Technician performs ph test and result is sent to the PI System PAS X requests result from PI AF Result is evaluated, during EBR execution. 14
15 Benefits of PAS X and PI AF One Screen, multiple sources of live data. Visual Equipment status 15
16 Benefits of PAS X and PI AF One location for multiple data sources: MES data SAP data OSIsoft PI System data QA information 16
17 Benefits Removal of over 1000 paper documents (to date) from Manufacturing Interface of Scales to the PI System and PAS-X eliminates manual entries Automated ph/cond/osmo/filter integrity testing. Result retrieval directly from the instrument to the PI System Greater Visibility on Status of Orders Process is tracked from Warehouse to Manufacturing to Warehouse Exception Free Manufacturing Mistake proofing in area of GDP errors and partially completed Paperwork eliminated No more searching for Docs / SOPs; automatically linked to Master Batch Record 17
18 Brought to you by
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