SANDRA L. JAMME, SLJ BUSINESS SERVICES, LLC EH&S CONSIDERATIONS FOR BIOTECH FACILITIES START-UPS CAL STATE UNIVERSITY EAST BAY TUESDAY, OCTOBER 25,
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1 SANDRA L. JAMME, SLJ BUSINESS SERVICES, LLC EH&S CONSIDERATIONS FOR BIOTECH FACILITIES START-UPS CAL STATE UNIVERSITY EAST BAY TUESDAY, OCTOBER 25, 2016
2 EH&S Considerations for Biotech Facilities Start-ups EH&S is an essential component that starts early in the process and can define a tenant improvement project. Effectively navigate requirements for biotech facility start-ups by understanding the interdependencies of construction, design, schedules, and safety to successfully deliver complex and time-sensitive projects.
3 Agenda Tenant Improvement (TI) Design Through Construction Relocation Readiness Destination Preparation Origin Preparation Site Closures Lessons Learned
4 TI Design Through Construction Key Stakeholders Executive Management Investors Users Real Estate Executive Define Requirements and Site Selection Location Employee Base & Similars Building (Feasibility, MEP and Accessibility) Property Management Identify Proper Zoning
5 TI Design Through Construction
6 TI Design Through Construction Design Architect with Applicable Experience Generate Block Plans for Utilization and Adjacencies Facilities Conducts Due Diligence Programming to Develop Basis of Design (BOD) Schematic Drawings (SDs) Site plan, floor plans, sections, elevations, renderings Design Drawings (DDs) Floor plans with full dimensions, door and window details and materials Construction Drawings (CDs) All pertinent information required to price and build
7 TI Design Through Construction Planning & Architectural Considerations for EHS Determine Control Zones for Constructability ***Coordinate with Multi-Tenant Buildings Identify Use and Generate Hazardous Materials Inventory Statement (HMIS) Validate Applicable Use Requirements (ie Biological, Chemistry, Radiation, Vivarium, NMR) Constructed Safety Components Eyewash & Safety Showers Fire Extinguishing Including Sprinklers, Preaction, Class D Chemical Fume Hoods or Vented BSCs Waste Station Collection Areas Egress & Assembly Area Identification Seismic Requirements
8 TI Design Through Construction Calif. Fire Code Physical Hazard Classifications Maximum Daily Average Daily Maximum In-Use Amount in Amount in Input Quantity in Input CBC Quantity in Units Input Units Input Units Units Input Unit Location Control Area Code Material Name CAS Number Material Assumptions Interior CA-1 2-Propanol I9516 Interior CA-1 Ammonia Solution Sigma-Aldrich Product Interior CA-1 Methyl alcohol Interior CA-1 Acetone Interior CA-1 Interior Hazardous Material? Maximum HazMat Quantities Flammable Liquids (gal): Quantity in CBC Units CBC Unit Flam IA California Fire Code Health Hazard Classifications: Combustible Liquid Class (gal): Flam IB Flam IC Comb II Oxidizer Class (lbs) Comb IIIB Comb IIIA (gal or lbs) Oxid 4 Oxid 3 Unstable - reactive (lbs) Oxid 2 Oxid 1 Unst 4 Unst 3 Unst 2 Unst 1 Water Reactive Class (lbs) WR 3 Flammable Oxidizing Cryo-Ox Corr-sol WR 2 WR 1 Corr-liq L Yes 1.32Gallons L Yes 2.64Gallons L Yes 2.64Gallons L Yes 0.26Gallons Ethanol L Yes 3.17Gallons CA-1 Ethanol L Yes 2.64Gallons Interior CA-1 Acetic Acid L Yes 3.17Gallons Interior CA-1 Formaldehyde F ML Yes 0.13Gallons Interior CA-1 Phenol, chloroform P L Yes 0.26Gallons Interior CA-1 Paraformaldehyde F L Yes 0.26Gallons Other Classes Cryogenic Highly Oxidizing Corrosive Corrosive Corrosive Highly Toxic (cf at Toxic (cf at Flamm Gases (cu ft at NTP) (gal) (lbs) (gal) (cf at NTP) Toxics (lbs) NTP) Toxic (lbs) NFP) Solid (lbs) Other High Tox- High ToxFlamm Corr-gas s&l gas Toxic-s&l Toxic-gas Solid Other
9 TI Design Through Construction Construction Drawings (CDs) and Permits Client Awards Project to General Contractor Architect Submits Permit Set Drawings To City Plan Check & Review Comments *** Allow 4-6 Weeks Based on Project Value *** Expeditor Available in some Jurisdictions Let s Start Building!! Construction TI Project Allow Weeks for Physical Construction and Longer for New Construction
10 EHS Professionals Are Critical to Minimize Business Disruption!!!
11 Relocation Readiness Define Scope of Work - Preparing for the Relocation Inspections with Regulatory Agencies Pre-Move Meetings with Staff Be Available Request Minimizing Chemical Orders Identify Locations and Collect Obsolete Waste Solicit Vendor to Lab Pack, Inventory and Move or Dispose of Hazardous Chemicals Support Equipment & Lab Decontamination Identify Strategies for Biologicals/ Live Cells Cold Storage Items (ie Cold Room, Freezers)
12 Relocation Readiness OSHA and other Regulatory Compliance, which may include: Injury & Illness Prevention Program (IIPP) Emergency Action Plan (EAP) Fire Prevention Program (FPP) Chemical Hygiene Program (CHP) Bloodborne Pathogen Program (BBP) Department of Transportation (DOT)
13 Relocation Readiness Permits Certified Unified Program Agency (CUPA) City or County Wastewater Fire Department Nuclear Regulatory Commission (NRC) Drug Enforcement Agency (DEA) Department of Occupational Health (DOSH or OSHA) Bay Area Air Quality Management District (BAAQMD) Environmental Protection Agency (EPA) Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) Institutional Animal Care and Use Committees (IACUC)
14 Relocation Readiness Site Preparation Hazard Communication at Labs and Buildings Identify and Train to Assembly Areas Post Emergency Contacts Generate and Post Evacuation Plans Procure and Stock First Aid Kits & AEDs Ensure Fire Extinguishers Are Available and Charged Confirm Safety Showers/ Eyewash Stations are Clear of Obstacles, Serviceable and Maintained
15 Relocation Readiness
16 Destination Preparation Certify Chemical Fume Hoods & Alarms Certify BioSafety Cabinets (BSCs), HEPAs, Canopies Waste Areas Identified & Prepared for Accumulation Safety Glasses & Other PPE Available Review Process Flows Seismic Bracing Conducted
17 Origin Preparation Identify Landlord Turn-Over Requirements Pre-Move Inspection To Confirm Testing and Other Requirements Develop Closure Plan to Comply With Requirements Submit Closure Plan to County & Landlord Implement Equipment and Lab Decontamination Plan Relocate and Remove Chemical and Biological Products Receive Sample Results and Waste Submit Closure package Essential to Timely Turn-Over
18 Site Closure Confirm Turn-Over Date Identify Landlord Exit Requirements Ensure All Chemicals Removed, Site Decontaminated, Tested and Results Received Turn-Over Closure Report Avoid Costly Hold-Over Costs Allow Time
19 Summary Define the Tenant Improvement (TI) Process Tips for Preparing for your Relocation How to Prepare the Destination Wrap Up Origin & Site Closures
20 Engage with Senior Management Early In Project Clearly Communicate Schedule and Expectations Manage Internal & External Resources Be Aware of Schedule Changes Talk with Local Agencies for Requirements/ Alliance Speak Up, Honest, Clear Be Involved with Regular Construction Teams Engage Employee Safety Teams
21 Questions Sandra L. Jamme SLJ Business Services, LLC
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