MEDICAL SCIENCES THE MALAYSIAN JOURNAL OF

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1 THE MALAYSIAN JOURNAL OF MEDICAL SCIENCES Volume 12, No. 2 ISSN X 2005 Penerbit Universiti Sains Malaysia Pulau Pinang Abstracts since 2004 are indexed in the Elsevier Bibliographic Databases, The Netherlands, Bioline, EBSCO Publishing, Index Copernicus and The British Library Inside database. i

2 Volume 12 No.2 ISSN X July 2005 THE MALAYSIAN JOURNAL OF MEDICAL SCIENCES Editor Mafauzy Mohamed Editorial Board Members Zabidi Azhar Mohd. Hussin Paediatric Wan Mohamad Wan Bebakar Medicine Jafri Malin Abdullah Neurosciences Zainul Fadziruddin Zainuddin Medical Biotechnology Asma Ismail Medical Biotechnology Mohd. Razali Salleh Psychological Medicine Ab. Rani Samsuddin Dental Sciences Rusli Nordin Community Medicine Harbindarjeet Singh Physiology Rogayah Ja afar Medical Education Rahmah Nordin Parasitology Mustaffa Embong Malaysia Timothy M.E. Davis Australia Advisory Board Members Khairul Anuar Abdullah Malaysia Brendan Gerard Loftus Ireland David H Lawson United Kingdom Shunichi Araki Japan Tatsuo Yamakawa Japan Clive Cockram Hong Kong Production Muhamad Saidi Hamzah Che Zaitun Che Ismail Sabri Mohd. Salleh Printing PUSTAKA AMAN PRESS SDN. BHD. < T > 4200-A, Jalan Sultan Yahya Petra, Peti Surat 67, Kota Bharu, Kelantan, Darulnaim, Malaysia. Tel : Fax : Publisher PENERBIT USM Bangunan D34, Universiti Sains Malaysia USM, Pulau Pinang Penerbit Universiti Sains Malaysia, 2005 The Malaysia Journal of Medical Sciences is the official journal of the School of Medical Sciences, Universiti Sains Malaysia ii

3 The Board of the MJMS would like to thank the following reviewers: Prof. Kamaruzaman Wan Su Prof. Mustafa Ali Mohamad Prof. Dr. Henry Rantai Gudum Prof. Zurin Adnan Prof. Nizam Isa Prof. Rogayah Jaafar Assoc. Prof. Dr. Abas Hussin Assoc. Prof. Dr. Haryati Abdul Rahman Dr. Nashiru Billa Dr. Sharifah Aziz International Islamic University, Kuantan, Malaysia Universiti Malaya, Malaysia Universiti Malaysia Sarawak, Malaysia International Medical Universiti, Malaysia Universiti Sains Malaysia, Malaysia Universiti Sains Malaysia, Malaysia International Medical Universiti, Malaysia Opinions expressed in the articles are those of the authors and do not necessarily reflect the views of the Editorial Board. The MJMS Editorial Board assumes no liability for any material published therein. iii

4 CONTENTS Editorial NEUROSCIENCES IN UNIVERSITY SAINS MALAYSIA; THE WAY TO GO FORWARD IN MALAYSIA WITH VISION 2020 Jafri Malin Abdullah 1 Review Article THE USE OF SNPS IN PHARMACOGENOMICS STUDIES Zilfalil Alwi 4 Original Articles 1. EVALUATION OF THE TERATOGENICITY OF AQUEOUS EXRACT OF LABISIA PUMILA VAR. ALATA IN RATS Wan Ezumi Mohd Fuad, Siti Amrah Sulaiman, Mohamad Nazrul Islam, Mohd Suhaimi Abdul Wahab, Syed Mohsin Sahil Jamalullail 2. IN VITRO EFFECTS OF PLANTAGO MAJOR EXTRACT ON UROLITHIASIS Sharifa Abdul Aziz, Tan Lee See, Lim Yew Khuay, Khairul Osman & Mohd. Azman Abu Bakar 3 ABSENCE OF RAS, C-MYC AND EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) MUTATIONS IN HUMAN GLIOMAS IN NORTH EAST MALAYSIAN PATIENTS AND ITS CLINICAL FACTORS ASSOCIATED WITH PATHOLOGICAL GRADING AFTER SIX YEARS OF DIAGNOSIS Mazira Mohammad Ghazali, Mohd Shahril Mohd Zan, Abdul Aziz Yusof, Jafri Abdullah, Hasnan Jaffar, Abdul Rahman Ariff, Win Mar@Slamah, Aini Ideris, Abdul Manaf Ali, Abdul Rahman Omar,Khatijah Yuosff, Mohd Azmi Mohd Lila, Fauziah Othman, Noordin Mohamed Mustapha, Mohd Nizam Isa & Nyi Nyi Naing 4. AMBULANCE SERVICES AT HOSPITAL UNIVERSITI SAINS MALAYSIA AND HOSPITAL KOTA BHARU: A RETROSPECTIVE STUDY OF CALLS Mohd Shaharudin Shah Che Hamzah, Rashidi Ahmad, Nik Hisamuddin Nik Abdul Rahman, Kasmah Wati Pardi, Naimah Jaafar, Wan Aasim Wan Adnan Kamaruddin Jaalam, Syed Mohsin Sahil Jamalullail 5. IMPACT OF A SPREADING EPIDEMIC ON MEDICAL STUDENTS Li-Cher Loh, Anita Mohd Ali, Ter-Hoay Ang, Ambiga Chelliah, iv

5 CONTENTS 6. USAGE OF TRADITIONAL MEDICINES AMONG ELDERLY AND PREDNISOLONE CONTAMINATION Zabidah Ismail, Rafeezul Mohamed, Mohd Hashim Mohd Hassan & Kamaruzaman Wan Su 50 Case Report 7. THE CO-EXISTENCE OF PURE RED CELL APLASIA AND AUTOIMMUNE HAEMOLYTIC ANAEMIA IN A CHILD WITH MALIGNANT LYMPHOMA Suhair Abbas Ahmed & Rosline Hassan 8. EXTRADURAL SPINAL SCHWANNOMA IN 12 YEAR OLD CHILD : A CASE REPORT Toh Charng Jeng, Jafri Malin Abdullah, Jain George,John Tharakan KJ, Sharon Casilda, Mazira Mohamad Ghazali, Hasnan Jaafar and Win Mar Salmah ABSTRACTS OF THESES APPROVED FOR THE M.Sc., M.Med. AND Ph.D. DEGREES AT THE SCHOOL OF MEDICAL SCIENCES, UNIVERSITY SAINS MALAYSIA, HEALTH CAMPUS, KUBANG KERIAN, KELANTAN, MALAYSIA. 10. INSTRUCTIONS TO CONTRIBUTORS v