Fluorescein Sodium Salt. For Further Manufacturing Use Only Not for Human or Animal Drug Use. Not classified as a hazard

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1 Safety Data Sheet Issuing Date 24May2010 Revision Date 25May2011 Revision Number 1 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND THE COMPANY/UNDERTAKING Product Name Product Code(s) Recommended Use Recommended Use Synonyms Company AMRESCO, LLC 6681 Cochran Road Solon, Ohio For Further Manufacturing Use Only t for Human or Animal Drug Use Yellow fluorine dye used as a fluorescent labeling reagent for proteins. AIZEN URANINE * CALCOCID URANINE B4315 * 9OCARBOXYPHENYL6HYDROXY3ISOXANTHONE, DISODIUM SALT * CERTIQUAL FLUORESCEINE * C.I. 766 * C. I. ACID YELLOW 73 * C.I DISODIUM SALT * C.I SODIUM SALT * D&C YELLOW NO. 8 * DISODIUM 6HYDROXY3OXO9XANTHENEOBENZOATE *FLUORESCEIN SODIUM * FLUORESCEIN SODIUM B.P * FLUORESCEIN, SOLUBLE * FLUORISTRIP A.T. * FULGLO * FUNDUSCEIN * FURANIUM * HIDACIDURANINE * NCIC54706 * RESORCINOL PHTHALEIN SODIUM * SODIUM FLUORESCEIN * SODIUM FLUORESCEINATE * SODIUM SALT OF HYDROXYO CARBOXYPHENYLFLUORONE * SOLUBLE FLUORESCEIN * SOLUBLE FLUORESCEINE *SPIRO(ISOBENZOFURAN1(3H),9'(9H)XANTHEN)3ONE, 3',6'DIHYDROXY, DISODIUM SALT * URANIN * URANINE * URANINE A EXTRA * URANINE O *URANINE SS * URANINE USP XII * URANINE WSS * URANINE YELLOW * 11824YELLOW * YELLOW * Emergency Telephone Number Chemtrec Company Phone Number Address info@amrescoinc.com 2. HAZARDS IDENTIFICATION GHS Classification Classification t classified as a hazard Page 1 / 6

2 Revision Date 25May COMPOSITION/INFORMATION ON INGREDIENTS Chemical Name FLUORESCEIN SODIUM SALT EC. EEC REACH Reg.. t available CAS Weight % Classification 4. FIRST AID MEASURES Eye Contact Skin Contact Inhalation Ingestion tes to Physician Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Wash off immediately with soap and plenty of water removing all contaminated clothes and shoes. Move to fresh air. If breathing becomes difficult, give oxygen. Clean mouth with water and afterwards drink plenty of water. Treat symptomatically. 5. FIREFIGHTING MEASURES Flammable Properties Flash Point Suitable Extinguishing Media Hazardous Combustion Products Explosion Data Sensitivity to Mechanical Impact Sensitivity to Static Discharge Protective Equipment and Precautions for Firefighters t flammable. t determined Dry chemical, CO2, water spray or regular foam. Carbon oxides. t sensitive. t sensitive. As in any fire, wear selfcontained breathing apparatus pressuredemand, MSHA/NIOSH (approved or equivalent) and full protective gear. 6. ACCIDENTAL RELEASE MEASURES Personal Precautions Methods for Containment Methods for Cleaning Up Avoid contact with skin, eyes and clothing. Use personal protective equipment. Ensure adequate ventilation. Prevent further leakage or spillage if safe to do so. Avoid dust formation. Pick up and transfer to properly labeled containers. Ventilate area and wash spill site after material pickup is complete. 7. HANDLING AND STORAGE Handling Handle in accordance with good industrial hygiene and safety practice. Page 2 / 6

3 Revision Date 25May2011 Storage Incompatible Products Keep containers tightly closed in a dry, cool and wellventilated place. Strong oxidizing agents. 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Engineering Measures Personal Protective Equipment Eye/Face Protection Skin and Body Protection Respiratory Protection Hygiene Measures Showers Eyewash stations Ventilation systems. Tightly fitting safety goggles. Wear protective gloves/clothing. If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positivepressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations. Handle in accordance with good industrial hygiene and safety practice. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Odor Odor Threshold Decomposition Temperature C Freezing Point Initial Boiling Point Physical State ph Flash Point Autoignition Temperature Boiling Point/Range Melting Point/Range Flammability Limits in Air Explosive Properties Oxidizing Properties Evaporation Rate 37.8 C Vapor Density Specific Gravity Solubility Partition Coefficient (noctanol/water) Viscosity Black Gray Powder t determined Upper Freely soluble. Lower 10. STABILITY AND REACTIVITY Stability Incompatible Products Conditions to Avoid Stable under recommended storage conditions. Strong oxidizing agents. ne known based on information supplied. Page 3 / 6

4 Revision Date 25May2011 Hazardous Decomposition Products Carbon oxides. Hazardous Polymerization Hazardous polymerization does not occur. 11. TOXICOLOGICAL INFORMATION Acute Toxicity Product Information Product does not present an acute toxicity hazard based on known or supplied information. Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation FLUORESCEIN SODIUM SALT 6721 mg/kg ( Rat ) Chronic Toxicity Chronic Toxicity known effect based on information supplied. Target Organ Effects Kidneys. 12. ECOLOGICAL INFORMATION Ecotoxicity The environmental impact of this product has not been fully investigated. 13. DISPOSAL CONSIDERATIONS Waste Disposal Method Contaminated Packaging Dispose of material in accordance with all federal, state, and local regulations. Dispose of in accordance with all federal, state and local regulations. 14. TRANSPORT INFORMATION IATA DOT t regulated t regulated 15. REGULATORY INFORMATION REACH Title VII Restrictions. Page 4 / 6

5 Revision Date 25May2011 Chemical Name FLUORESCEIN SODIUM SALT Component FLUORESCEIN SODIUM SALT ( ) International Inventories Dangerous ISHA Harmful Prohibited for Manufacturing, Importing, Transferring, or Supplying Organic Solvents ISHA Harmful Requiring Permission Harmful Whose Names Are to be Indicated on the Label Pollution Release and Transfer Registry (Class II): Toxic Chemical Classification Listing (TCCL) Toxic Chemicals Pollution Release and Transfer Registry (Class I): Toxic Release Inventory (TRI) Group I Poison and Deleterious Control Law: Toxic Release Inventory (TRI) Group II TSCA EINECS/ELINCS ENCS IECSC KECL PICCS AICS Does not Comply U.S. Federal Regulations SARA 313 Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372. SARA 311/312 Hazard Categories Acute Health Hazard Chronic Health Hazard Fire Hazard Sudden Release of Pressure Hazard Reactive Hazard Clean Water Act This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR and 40 CFR ). Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61) This product does not contain any substances regulated as hazardous air pollutants (HAPS) under Section 112 of the Clean Air Act Amendments of CERCLA U.S. State Regulations California Proposition 65 This product does not contain any Proposition 65 chemicals. Page 5 / 6

6 Revision Date 25May2011 International Regulations Mexico Grade. Canada WHMIS Hazard Class t determined 16. OTHER INFORMATION Issuing Date Revision Date 24May May2011 Revision te Recommended Restrictions Disclaimer The information provided on this MSDS is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text. End of MSDS Page 6 / 6