MATERIAL SAFETY DATA SHEET

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1 MATERIAL SAFETY DATA SHEET Sectio α-ketoglutaric ACID. 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION MSDS Name: Synonyms: Company Identification: α -Ketoglutaric acid 2-Ketoglutaric acid; 2-Oxopentanedioic acid; 2-Oxoglutaric acid Sisco Research Laboratories Pvt. Ltd. Andheri (East), Mumbai Tel : Fax : Website : COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name: % EINECS# α -Ketoglutaric acid 99% HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Warning! The toxicological properties of this material have not been fully investigated. Causes eye irritation and possible injury. May cause skin and respiratory tract irritation. Keep refrigerated. (Store below 4C/39F.) Target Organs: Eyes. Potential Health Effects Eye: Causes eye irritation. May result in corneal injury. Ingestion: Inhalation: Chronic: 4 - FIRST AID MEASURES May cause skin irritation. May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. No information found. Eyes: Ingestion: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid immediately. In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.

2 Inhalation: Notes to Physician: 5 - FIRE FIGHTING MEASURES General Information: Extinguishing Media: 6 - ACCIDENTAL RELEASE MEASURES If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.get medical aid. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Use extinguishing media most appropriate for the surrounding fire. General Information: Spills/Leaks: Use proper personal protective equipment as indicated in Section 8. Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. 7 HANDLING AND STORAGE Handling: Storage: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigeration has been recommended. 8 EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits Personal Protective Equipment Eyes: Wear chemical splash goggles. Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

3 Respirators: A respiratory protection program that meets OSHA's 29 CFR and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: white Melting Point: deg C Molecular Formula: C 5 H 6 O 5 Molecular Weight: STABILITY AND REACTIVITY Chemical Stability: Conditions to Avoid: Incompatibilities with Other Materials : Hazardous Decomposition Products : Stable at room temperature in closed containers under normal storage and handling conditions. Dust generation, excess heat. Strong oxidizing agents, strong bases. Hazardous Polymerization : Has not been reported TOXICOLOGICAL INFORMATION Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. RTECS#: LD50/LC50: Carcinogenicity: Other: CAS# : None listed RTECS:. RTECS:CAS# : Oral, rat: LD50 = >90 ml/kg 2-Ketoglutaric acid - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.Water - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop ECOLOGICAL INFORMATION 13 - DISPOSAL CONSIDERATIONS 14 - TRANSPORT INFORMATION IATA IMO RID/ADR Shipping Name: Not regulated Not regulated Not regulated as a hazardous as a hazardous as a hazardous material material material Hazard Class: UN Number:

4 Packing Group: 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 41 Risk of serious damage to eyes. Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection)CAS# : 0 Canada CAS# is listed on Canada's DSL List US Federal TSCA CAS# is listed on the TSCA Inventory. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule CERCLA Hazardous Substances and corresponding RQs SARA Section 302 Extremely Hazardous Substances SARA Codes None of the chemicals in this material have a SNUR under TSCA. None of the chemicals in this material have an RQ. None of the chemicals in this product have a TPQ. CAS # : acute. Section 313 No chemicals are reportable under Section 313. Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act: OSHA: None of the chemicals in this product are listed as Hazardous Substances under the CWA.None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. STATE 2-Ketoglutaric acid is not present on state lists from CA, PA, MN, MA, FL, or NJ. Water is not present on state lists from CA, PA, MN, MA, FL, or NJ. California Prop 65 California No Significant Risk Level: None of the chemicals in this product are listed.ection 16 - Other Information

5 16 - ADDITIONAL INFORMATION SISCO RESEARCH LABORATORIES provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.