: Hematoxylin Gill II

Transcription

1 Version: 1.0 SECTION 1: Identification 1.1. Identification Trade name Product code : : , , , 38016SS4C 1.2. Recommended use and restrictions on use Recommended use Restrictions on use 1.3. Supplier : Nuclear stain : Other uses Leica Biosystems Richmond, Inc 5205 Route 12 Richmond, IL USA T LBSNA-LBS-QA@leicabiosystems.com - leicabiosystems.com 1.4. Emergency telephone number Organization/Company Emergency number ChemTrec International Calls (call collect) Australia 24 Hr Poisons Information Centre SECTION 2: Hazard(s) identification 2.1. Classification of the substance or mixture GHS-US classification Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 2 Causes skin irritation Causes serious eye irritation 2.2. GHS Label elements, including precautionary statements GHS-US labeling Hazard pictograms (GHS-US) : Signal word (GHS-US) Hazard statements (GHS-US) Precautionary statements (GHS-US) GHS07 : Warning : Causes skin irritation Causes serious eye irritation : Wash thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If skin irritation occurs: Get medical advice/attention If eye irritation persists: Get medical advice/attention Take off contaminated clothing and wash it before reuse 11/21/2017 EN (English US) Page 1

2 2.3. Other hazards which do not result in classification 2.4. Unknown acute toxicity (GHS US) SECTION 3: Composition/Information on ingredients 3.1. Substances 3.2. Mixtures Name Product identifier % GHS-US classification Ethylene Glycol (CAS No) < 30 Acute Tox. 4 (Oral), H302 acetic acid (CAS No) < 2 Flam. Liq. 3, H226 Skin Corr. 1A, H314 Full text of hazard classes and H-statements : see section 16 SECTION 4: First-aid measures 4.1. Description of first aid measures First-aid measures general First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact First-aid measures after ingestion : Call a poison center/doctor/physician if you feel unwell. : Remove person to fresh air and keep comfortable for breathing. : Rinse skin with water/shower. Remove/Take off immediately all contaminated clothing. If skin irritation occurs: Get medical advice/attention. : Rinse eyes with water as a precaution. : Rinse mouth. Call a poison center/doctor/physician if you feel unwell Most important symptoms and effects (acute and delayed) Symptoms/effects after skin contact : Irritation Immediate medical attention and special treatment, if necessary Treat symptomatically. SECTION 5: Fire-fighting measures 5.1. Suitable (and unsuitable) extinguishing media Suitable extinguishing media 5.2. Specific hazards arising from the chemical Fire hazard : Water spray. Dry powder. Foam. Carbon dioxide. on direct fire hazard Special protective equipment and precautions for fire-fighters Protection during firefighting SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures : Do not attempt to take action without suitable protective equipment. Self-contained breathing apparatus. Complete protective clothing For non-emergency personnel Emergency procedures For emergency responders Protective equipment : Ventilate spillage area. Avoid contact with skin and eyes. : Do not attempt to take action without suitable protective equipment. For further information refer to section 8: "Exposure controls/personal protection" Environmental precautions Avoid release to the environment. 11/21/2017 EN (English US) 2/8

3 6.3. Methods and material for containment and cleaning up Methods for cleaning up Other information 6.4. Reference to other sections For further information refer to section 13. SECTION 7: Handling and storage : Take up liquid spill into absorbent material. Notify authorities if product enters sewers or public waters. : Dispose of materials or solid residues at an authorized site Precautions for safe handling Precautions for safe handling Hygiene measures : Ensure good ventilation of the work station. Wear personal protective equipment. Avoid contact with skin and eyes. : Wash contaminated clothing before reuse. Do not eat, drink or smoke when using this product. Always wash hands after handling the product Conditions for safe storage, including any incompatibilities Technical measures Storage conditions SECTION 8: Exposure controls/personal protection 8.1. Control parameters : Comply with applicable regulations. : Store in a well-ventilated place. Keep cool. Keep container tightly closed. ACGIH ACGIH TWA (ppm) 25 ppm ACGIH ACGIH STEL (mg/m³) 10 mg/m³ ACGIH ACGIH STEL (ppm) 50 ppm ACGIH ACGIH Ceiling (mg/m³) 100 mg/m³ (Ethylene glycol; USA; Momentary value; TLV - Adopted Value) ACGIH Remark (ACGIH) Kidney dam; URT & eye irr ACGIH ACGIH TWA (ppm) 10 ppm (Acetic acid; USA; Time-weighted average exposure limit 8 h; TLV - Adopted Value) ACGIH ACGIH STEL (ppm) 15 ppm (Acetic acid; USA; Short time value; TLV - Adopted Value) 8.2. Appropriate engineering controls Appropriate engineering controls Environmental exposure controls : Ensure good ventilation of the work station. : Avoid release to the environment Individual protection measures/personal protective equipment Hand protection: Protective gloves Eye protection: Safety glasses Skin and body protection: Wear suitable protective clothing 11/21/2017 EN (English US) 3/8

4 Respiratory protection: In case of insufficient ventilation, wear suitable respiratory equipment SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state : Liquid Color : dark red Odor : Vinegar odour Odor threshold ph : Melting point : Freezing point Boiling point Flash point : 212 Relative evaporation rate (butyl acetate=1) Flammability (solid, gas) :. Vapor pressure Relative vapor density at 20 C Relative density Specific gravity / density : 1.11 Solubility Log Pow Auto-ignition temperature Decomposition temperature Viscosity, kinematic Viscosity, dynamic Explosion limits Explosive properties Oxidizing properties 9.2. Other information SECTION 10: Stability and reactivity Reactivity Chemical stability Stable under normal conditions Possibility of hazardous reactions No dangerous reactions known under normal conditions of use Conditions to avoid Avoid contact with hot surfaces. Heat. No flames, no sparks. Eliminate all sources of ignition. 11/21/2017 EN (English US) 4/8

5 10.5. Incompatible materials Hazardous decomposition products Under normal conditions of storage and use, hazardous decomposition products should not be produced. SECTION 11: Toxicological information Information on toxicological effects Acute toxicity LD50 oral rat ATE US (oral) LD50 oral rat ATE US (oral) Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity > 5000 mg/kg (Rat; Literature study) 500 mg/kg body weight 3310 mg/kg body weight (Rat; Other; Read-across) 3310 mg/kg body weight : Causes skin irritation. ph: : Causes serious eye irritation. ph: Reproductive toxicity Specific target organ toxicity single exposure Specific target organ toxicity repeated exposure Aspiration hazard Symptoms/effects after skin contact SECTION 12: Ecological information Toxicity Ecology - general : Irritation. : The product is not considered harmful to aquatic organisms or to cause long-term adverse effects in the environment. EC50 Daphnia 1 > mg/l (EC50; 24 h) LC50 fish mg/l (LC50; 96 h; Salmo gairdneri) Persistence and degradability Persistence and degradability Biochemical oxygen demand (BOD) Chemical oxygen demand (COD) Readily biodegradable in water. Biodegradable in the soil g O₂/g substance 1.24 g O₂/g substance 11/21/2017 EN (English US) 5/8

6 ThOD BOD (% of ThOD) g O₂/g substance Persistence and degradability Biochemical oxygen demand (BOD) Chemical oxygen demand (COD) ThOD Readily biodegradable in water. Biodegradable in the soil. Highly mobile in soil g O₂/g substance 1.03 g O₂/g substance 1.07 g O₂/g substance Bioaccumulative potential BCF fish 1 10 (BCF; 72 h) BCF other aquatic organisms (BCF) BCF other aquatic organisms (BCF; 24 h) Log Pow (Experimental value) Bioaccumulative potential Low potential for bioaccumulation (BCF < 500). BCF fish (BCF; Pisces) Log Pow (Experimental value; 25 C) Bioaccumulative potential Low potential for bioaccumulation (Log Kow < 4) Mobility in soil Surface tension Surface tension Log Koc Ecology - soil N/m (20 C) N/m (20 C) log Koc,0.06; QSAR May be harmful to plant growth, blooming and fruit formation Other adverse effects SECTION 13: Disposal considerations Disposal methods Waste treatment methods : Dispose of contents/container in accordance with licensed collector s sorting instructions. SECTION 14: Transport information Department of Transportation (DOT) In accordance with DOT Transport by sea 11/21/2017 EN (English US) 6/8

7 Air transport SECTION 15: Regulatory information US Federal regulations Listed on the United States TSCA (Toxic Substances Control Act) inventory Subject to reporting requirements of United States SARA Section 313 CERCLA RQ 5000 lb International regulations CANADA Listed on the Canadian DSL (Domestic Substances List) EU-Regulations National regulations US State regulations U.S. - California - Proposition 65 - Carcinogens List U.S. - California - Proposition 65 - Developmental Toxicity U.S. - California - Proposition 65 - Reproductive Toxicity - Female No Yes No No U.S. - California - Proposition 65 - Reproductive Toxicity - Male No significant risk level (NSRL) U.S. - New Jersey - Right to Know Hazardous Substance List U.S. - Pennsylvania - RTK (Right to Know) List SECTION 16: Other information Full text of H-phrases: --- H H H Flammable liquid and vapor Harmful if swallowed Causes severe skin burns and eye damage SDS US Leica 11/21/2017 EN (English US) 7/8

8 This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product 11/21/2017 EN (English US) 8/8