SECTION 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

Transcription

1 Revision Number 12 SECTION 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identification Product Description: Cat No. : Relevant identified uses of the substance or mixture and uses advised against Recommended Use Uses advised against In vitro diagnostic All other uses 1.3. Details of the supplier of the safety data sheet Company address 1.4. Emergency telephone number Phadia AB Rapsgatan 7P P.O. Box UPPSALA Sweden safetydatasheet.idd@thermofisher.com UK: Malta: Belgium Ireland Classification of the substance or mixture SECTION 2: HAZARDS IDENTIFICATION CLP Classification - Regulation (EC) No 1272/2008 Physical hazards Based on available data, the classification criteria are not met Health hazards Based on available data, the classification criteria are not met Environmental hazards Based on available data, the classification criteria are not met For the full text of the H-statements mentioned in this Section, see Section Label elements Page 1 / 9

2 2.3. Other hazards 3.1. Substances 3.2. Mixtures SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS Component CAS-No EC-No. Weight % CLP Classification - Regulation (EC) No 1272/2008 Buffer solution N/A Methylumbelliferyl-Beta-D-galact opyranoside N/A < chloro-2-methyl-4-isothiazolin-3- one [EC no ] and 2-methyl-2H -isothiazol-3-one [EC no ] (3:1) < Acute Tox. 3 (H301) Acute Tox. 3 (H311) Acute Tox. 3 (H331) Skin Corr. 1B (H314) Skin Sens. 1 (H317) Aquatic Acute 1 (H400) Aquatic Chronic 1 (H410) For the full text of the H-statements mentioned in this Section, see Section Description of first aid measures SECTION 4: FIRST AID MEASURES Eye Contact Skin Contact Ingestion Inhalation Protection of First-aiders Rinse thoroughly with plenty of water, also under the eyelids. Wash off immediately with soap and plenty of water. Clean mouth with water and drink afterwards plenty of water. Not applicable. Not Applicable Most important symptoms and effects, both acute and delayed 4.3. Indication of any immediate medical attention and special treatment needed Notes to Physician Treat symptomatically. SECTION 5: FIREFIGHTING MEASURES 5.1. Extinguishing media Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Extinguishing media which must not be used for safety reasons 5.2. Special hazards arising from the substance or mixture Page 2 / 9

3 Hazardous Combustion Products 5.3. Advice for firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures Wear protective gloves/clothing and eye/face protection Environmental precautions Dispose of in accordance with local regulations Methods and material for containment and cleaning up Wipe up with adsorbent material (e.g. cloth, fleece). Dispose of waste product or used containers according to local regulations Reference to other sections Refer to protective measures listed in Sections 8 and Precautions for safe handling SECTION 7: HANDLING AND STORAGE Wash thoroughly after handling. Do not eat, drink or smoke when using this product Conditions for safe storage, including any incompatibilities Observe instructions for use Specific end use(s) Observe instructions for use Control parameters Exposure limits SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION Component Austria Denmark Switzerland Poland Norway 5-chloro-2-methyl-4-i sothiazolin-3-one [EC no ] and 2-methyl-2H -isothiazol-3-one [EC no ] (3:1) Haut MAK-TMW: 0.05 mg/m 3 8 Stunden Biological limit values This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific Page 3 / 9

4 regulatory bodies. Monitoring methods BS EN 14042:2003 Title Identifier: Workplace atmospheres. Guide for the application and use of procedures for the assessment of exposure to chemical and biological agents. Derived No Effect Level (DNEL) Predicted No Effect Concentration (PNEC) 8.2. Exposure controls Engineering Measures None under normal use conditions. Personal protective equipment Eye Protection Hand Protection No special protective equipment required. No special protective equipment required. Glove material Breakthrough time Glove thickness - EU standard Glove comments Skin and body protection No special protective equipment required. Respiratory Protection Large scale/emergency use Small scale/laboratory use No protective equipment is needed under normal use conditions. No protective equipment is needed under normal use conditions No personal respiratory protective equipment normally required. Hygiene Measures Environmental exposure controls Handle in accordance with good industrial hygiene and safety practice. Dispose of contents/containers in accordance with local regulations. SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 9.1. Information on basic physical and chemical properties Appearance Physical State Clear Liquid Odor None Odor Threshold None ph 6.5 Melting Point/Range Softening Point Boiling Point/Range 100 C Flash Point Not applicable Evaporation Rate Flammability (solid,gas) Not flammable Explosion Limits Not applicable Method - No information available Vapor Pressure Vapor Density (Air = 1.0) Specific Gravity / Density 1 g/cm3 Bulk Density Page 4 / 9

5 Water Solubility Soluble in water Solubility in other solvents No information available Partition Coefficient (n-octanol/water) Component log Pow <3 5-chloro-2-methyl-4-isothiazolin-3-one [EC -isothiazol-3-one [EC no ] (3:1) Autoignition Temperature Not applicable Decomposition Temperature Not applicable Viscosity Explosive Properties Not applicable Oxidizing Properties Not applicable 9.2. Other information SECTION 10: STABILITY AND REACTIVITY Reactivity Chemical stability Stable under normal conditions Possibility of hazardous reactions Hazardous Polymerization Hazardous Reactions Conditions to avoid Incompatible materials Hazardous polymerization does not occur. None under normal processing Hazardous decomposition products Information on toxicological effects SECTION 11: TOXICOLOGICAL INFORMATION Product Information Product does not present an acute toxicity hazard based on known or supplied information. (a) acute toxicity; Oral. Dermal. Inhalation. Component LD50 Oral LD50 Dermal LC50 Inhalation LD50 = 53 mg/kg ( Rat ) 4h 0.33 mg/l ( Rat ) (b) skin corrosion/irritation; (c) serious eye damage/irritation;.. (d) respiratory or skin sensitization; Respiratory. Skin. Page 5 / 9

6 (e) germ cell mutagenicity;. Component Test method Test species Study result in vivo in vitro negative (f) carcinogenicity; There are no known carcinogenic chemicals in this product. Component Test method Test species / Duration Study result negative (g) reproductive toxicity;. Component Test method Test species / Duration Study result negative Animal testing did not show any effects on fetal development (h) STOT-single exposure; (i) STOT-repeated exposure; (j) aspiration hazard;... Symptoms / effects,both acute and delayed SECTION 12: ECOLOGICAL INFORMATION Toxicity Ecotoxicity effects Component Freshwater Fish Water Flea Freshwater Algae Microtox LC50 96 h 0.19mg/l ( Rainbow trout Oncorhynchus mykiss ) EC50 48 h mg/l OECD Test 202 ( Daphnia magna ) ERC50 72 h 0,027 mg/l (Selenastrum capricornutum)) Persistence and degradability Bioaccumulative potential Component log Pow Bioconcentration factor (BCF) < Mobility in soil Results of PBT and vpvb assessment Other adverse effects Endocrine Disruptor Information Persistent Organic Pollutant Ozone Depletion Potential This preparation contains no substance considered to be persistent, bioaccumulating nor toxic (PBT). This preparation contains no substance considered to be very persistent nor very bioaccumulating (vpvb). No known effect. No known effect. SECTION 13: DISPOSAL CONSIDERATIONS Page 6 / 9

7 13.1. Waste treatment methods Waste from Residues / Unused Products Contaminated Packaging Dispose of in accordance with local regulations. Dispose of in accordance with local regulations. European Waste Catalogue (EWC) Chemicals other than those mentioned in Other Information SECTION 14: TRANSPORT INFORMATION IMDG/IMO Not regulated UN number UN proper shipping name Transport hazard class(es) Packing group ADR Not regulated UN number UN proper shipping name Transport hazard class(es) Packing group IATA Not regulated UN number UN proper shipping name Transport hazard class(es) Packing group Environmental hazards No hazards identified Special precautions for user No special precautions required Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable, packaged goods. SECTION 15: REGULATORY INFORMATION Safety, health and environmental regulations/legislation specific for the substance or mixture International Inventories X = listed Component EINECS ELINCS NLP TSCA DSL NDSL PICCS ENCS IECSC AICS KECL 5-chloro-2-methyl-4-isothiazoli n-3-one [EC no ] and 2-methyl-2H -isothiazol-3-one [EC no ] (3:1) X - X X X - X National Regulations Component Germany - Water Classification (VwVwS) Germany - TA-Luft Class 5-chloro-2-methyl-4-isothiazolin- 3-one [EC no ] and 2-methyl-2H -isothiazol-3-one WGK 3 Page 7 / 9

8 [EC no ] (3:1) Take note of Control of Substances Hazardous to Health Regulations (COSHH) 2002 and 2005 Amendment. Take note of Dir 94/33/EC on the protection of young people at work. Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work Chemical safety assessment A Chemical Safety Assessment/Report (CSA/CSR) is not required. Full text of H-Statements referred to under sections 2 and 3 H331 - Toxic if inhaled H301 - Toxic if swallowed H314 - Causes severe skin burns and eye damage H317 - May cause an allergic skin reaction H400 - Very toxic to aquatic life H410 - Very toxic to aquatic life with long lasting effects H311 - Toxic in contact with skin SECTION 16: OTHER INFORMATION Legend CAS - Chemical Abstracts Service TSCA - United States Toxic Substances Control Act Section 8(b) Inventory EINECS/ELINCS - European Inventory of Existing Commercial Chemical DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances/EU List of Notified Chemical Substances Substances List PICCS - Philippines Inventory of Chemicals and Chemical Substances ENCS - Japanese Existing and New Chemical Substances IECSC - Chinese Inventory of Existing Chemical Substances AICS - Australian Inventory of Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances NZIoC - New Zealand Inventory of Chemicals WEL - Workplace Exposure Limit TWA - Time Weighted Average ACGIH - American Conference of Governmental Industrial Hygienists IARC - International Agency for Research on Cancer DNEL - Derived No Effect Level PNEC - Predicted No Effect Concentration RPE - Respiratory Protective Equipment LD50 - Lethal Dose 50% LC50 - Lethal Concentration 50% EC50 - Effective Concentration 50% NOEC - No Observed Effect Concentration POW - Partition coefficient Octanol:Water PBT - Persistent, Bioaccumulative, Toxic vpvb - very Persistent, very Bioaccumulative ADR - European Agreement Concerning the International Carriage of ICAO/IATA - International Civil Aviation Organization/International Air Dangerous Goods by Road Transport Association IMO/IMDG - International Maritime Organization/International Maritime MARPOL - International Convention for the Prevention of Pollution from Dangerous Goods Code Ships OECD - Organisation for Economic Co-operation and Development ATE - Acute Toxicity Estimate BCF - Bioconcentration factor VOC - Volatile Organic Compounds Key literature references and sources for data Suppliers safety data sheet, Chemadvisor - LOLI, Merck index, RTECS Physical hazards Health Hazards Environmental hazards On basis of test data Calculation method Calculation method Training Advice Chemical hazard awareness training, incorporating labelling, Safety Data Sheets (SDS), Personal Protective Equipment (PPE) and hygiene. Revision Date 24-Nov-2015 Revision Summary Revision Summary SDS sections updated, 16. This safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006 Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information Page 8 / 9

9 relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text End of Safety Data Sheet Page 9 / 9