Material Safety Data Sheet acc. to ISO/DIS 11014

Transcription

1 Ni-NTA Sepharose, Ni-NTA Superflow Page 1 of 5 Last date of revision: September 10 Version 2 1. Product and Company Information Product Name Ni-NTA Sepharose, Ni-NTA Superflow Product Number Component of the Strep/His Starter Kit (Cat. No ) Cat. no.: up to , , , up to , , , up to Company IBA GmbH Rudolf-Wissell-Str Goettingen Germany Technical Phone Fax info@iba-go.com Web Emergency Phone (Poison Information Center Goettingen, Germany, 24h) 2. Composition/Information on Ingredients Hazardous Ingredients % CAS # LD 50 (specific) *Ni-NTA 50 - N/A Sepharose/Superflow Ethanol oral rat: 7060 mg/kg oral human: 1400 mg/kg Nickle N/A intraperitoneal rat: 250 mg/kg Water Rest * Ni-NTA Sepharose & Ni-NTA Superflow Contains nickel-nitrilotriacetic acid. Harmful, sensitizer, and flammable. Risk and safety phrases: R /43. S Hazards Identification Hazard description: Information concerning particular hazards for human and environment: Classification system Harmful Flammable. Harmful if swallowed. Limited evidence of a carcinogenic effect. May cause sensitisation by Inhalation and skin contact. Warning - this preparation contains a substance not yet tested completely. The Classification is according to the latest editions of the EU-lists, and extended by Company and literature data. NFPA ratings (scale 0-4) Health = 2; Fire = 3; Reactivity = 0 WHMIS ratings (scale 0-4) Health = 2; Fire = 3; Reactivity = 0

2 Ni-NTA Sepharose, Ni-NTA Superflow Page 2 of 5 Last date of revision: September 10 Version 2 4. First Aid Measures After inhalation: After skin contact: After eye contact: After swallowing: Supply fresh air; consult doctor in case of complaints. Immediately wash with water and soap and rinse thoroughly. Rinse opened eye for several minutes under running water. Then consult a doctor. Call for a doctor immediately. 5. Fire Fighting Measures Suitable extinguishing agents: Protective equipment: CO 2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Do not inhale explosion gases or combustion gases. 6. Accidental Release Measures Person-related safety precautions: Measures for environmental protection: Measures for cleaning/collecting: Ensure adequate ventilation Do not allow to enter sewers/ surface or ground water. Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Dispose contaminated material as waste according to item Handling and Storage S Handling: Information for safe handling: Information about fire - and explosion protection: Storage: Requirements to be met by storerooms and receptacles: Information about storage in one common storage facility: Further Information about storage conditions: Ensure good ventilation/exhaustion at the workplace. Keep ignition sources away - Do not smoke. No special requirements. Not required. Keep receptacle tightly sealed. 8. Exposure Controls and Personal Protection Additional information about design of technical systems: General protective and hygienic measures: Protection of hands: No further data; see item 7. Keep away from foodstuffs and beverages. Immediately remove all soiled and contaminated clothing. Wash hands before breaks and at the end of work. The selection of the suitable gloves does not only depend on the material, but also on further marks of

3 Ni-NTA Sepharose, Ni-NTA Superflow Page 3 of 5 Eye protection: quality and varies from manufacturer to manufacturer. Tightly sealed goggles. 9. Physical and Chemical Properties P General Information: Form: Color: Odor: Change in condition: Melting point/melting range: Boiling point/boiling range: Flash point: Ignition temperature: Self-igniting: Danger of explosion: Explosion limits: Suspension According to product specification Characteristic Lower: 3.5 Vol % Upper: 15.0 Vol % Vapour pressure at 20 C 59 hpa (44 mm Hg) (68 F): Density: Not determined. Solubility in / Miscibility with Fully miscible. water: ph-value at 20 C (68 F): Stability and Reactivity Undetermined. Undetermined C ( F) 425 C (797 F) Product is not self-igniting. Product is not explosive. However, formation of explosive air/vapour mixtures are possible. Stability: Polymerization: Hazardous decomposition products: Materials to avoid: Stable under recommended storage conditions. None under normal processing. Thermal decomposition can lead to release of irritating gases and vapours. Aldehydes. Sulphur oxides. Carbon monoxide. Hydrogen chloride gas. Nitrogen oxides (nox). Incompatible with strong acids and bases. Oxidising agents (strong). Heavy metals. 11. Toxicological Information On the skin: On the eye: Sensitization: Additional toxicological Information: Irritant to skin and mucous membranes. Irritating effect. Sensitization possible through Inhalation. Sensitization possible through skin contact. The product shows the following dangers according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest Version: Harmful, irritant.

4 Ni-NTA Sepharose, Ni-NTA Superflow Page 4 of Ecological Information General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage System. 13. Disposal Considerations Recommendation: Recommendation: Recommended cleansing agents: Must not be disposed together with household garbage. Do not allow product to reach sewage System. Disposal must be made according to official regulations Water, if necessary together with cleansing agents. 14. Transport Information I Hazard class: 3 Identification number: UN1170 Proper shipping name (technical name): Ethanol solution Label: 3 Land transport ADR/RID (cross-border): ADR/RID class: 3 Flammable liquids Danger code (Kemler): 30 UN-Number: 1170 Description of goods: 1170 Ethanol solution (Ethyl alcohol solution) Maritime transport IMDG: IMDG Class: 3 UN Number: 1170 Marine pollutant: No Propper shipping name: Ethanol solution (Ethyl alcohol solution) Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: 3 UN/ID Number: 1170 Label: 3 Propper shipping name: Ethanol solution

5 Ni-NTA Sepharose, Ni-NTA Superflow Page 5 of Regulations LABELLING ACCORDING TO EU GUIDELINES: The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous Materials. Code letter and hazard designation of product: Xn Harmful Risk phrases: 10 Flammable. 22 Harmful if swallowed 40 Limited evidence of a carcinogenic effect. 42/43 May cause sensitisation by Inhalation and skin contact. Safety phrases: 13 Keep away from food, drink and animal feeding stuffs. 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 36 Wear suitable protective clothing. 46 If swallowed, seek medical advice immediately and show this container or label. Special labelling of certain preparations: Warning - this preparation contains a substance not yet tested completely. National regulations: Technical instructions (air): Class Share in % IM Water hazard class: Water hazard class 1 (Selfassessment): slightly hazardous for water. 16. Other Information I WARRANTY The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. IBA GmbH shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. Copyright 2004 IBA GmbH. License granted to make unlimited paper copies for internal use only. DISCLAIMER For R&D use only. Not for drug, household or other uses.