Material Safety Data Sheet

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1 Material Safety Data Sheet NFPA HMIS Personal Protective Equipment 1 Health Hazard Fire Hazard 2 1 See Section 15. Section 1. Chemical Product and Company Identification Common Name/ Trade Name Manufacturer Commercial Name(s) Synonym Chemical Name L-Carnosine SPECTRUM LABORATORY PRODUCTS INC S. SAN PEDRO STREET GARDENA, CA 9248 Beta-Alanyl-L-Histidine; Ignotine L-Carnosine Catalog Number(s). CAS# RTECS TSCA CI# C MS38 IN CASE OF EMERGENCY CHEMTREC (24hr) Page Number: 1 TSCA 8(b) inventory: L-Carnosine Chemical Family Chemical Formula Supplier C9-H14-N4-O3 SPECTRUM LABORATORY PRODUCTS INC S. SAN PEDRO STREET GARDENA, CA 9248 CALL (31) Section 2.Composition and Information on Ingredients Name CAS # Exposure Limits TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight 1) {L-}Carnosine Toxicological Data on Ingredients L-Carnosine: ORAL (LD5): Acute: >1493 mg/kg [Mouse]. Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant). Slightly hazardous in case of ingestion, of inhalation. CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: Repeated or prolonged exposure is not known to aggravate medical condition.

2 L-Carnosine Page Number: 2 Section 4. First Aid Measures Eye Contact Skin Contact Serious Skin Contact Inhalation Serious Inhalation Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention. In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Cold water may be used.wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Ingestion Serious Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances May be combustible at high temperature. CLOSED CUP: Higher than 93.3 C (2 F). These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...). Slightly flammable to flammable in presence of heat. Explosion Hazards in Presence of Various Substances Risks of explosion of the product in presence of mechanical impact: Risks of explosion of the product in presence of static discharge: Fire Fighting Media and Instructions Fire Hazards Explosion Hazards SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. As with most organic solids, fire is possible at elevated temperatures Material in powder form, capable of creating a dust explosion. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

3 L-Carnosine Page Number: 3 Section 7. Handling and Storage Precautions Storage Keep locked up.. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, moisture. Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 4 C (39.2 F). Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Personal Protection in Case of a Large Spill Exposure Limits Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Powdered solid.) Odor Molecular Weight ph (1% soln/water) g/mole Taste Color White. Boiling Point Melting Point 253 C (487.4 F) Critical Temperature Specific Gravity Vapor Pressure Not applicable. Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties See solubility in water. Solubility Soluble in cold water. Section 1. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances The product is stable. Excess heat, imcompatible materials Reactive with oxidizing agents.

4 L-Carnosine Page Number: 4 Corrosivity Corrosivity Polymerization Hygroscopic; keep container tightly closed. Will not occur. Section 11. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Inhalation. Ingestion. Acute oral toxicity (LD5): >1493 mg/kg [Mouse]. Hazardous in case of skin contact (irritant). Slightly hazardous in case of ingestion, of inhalation. May cause adverse reproductive effects based on animal test data. Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: May cause eye irritation. Inhalation: May cause respiratory tract irritation. Ingestion: May cause irritation of the digestive (gastrointestinal) tract. May affect behavior/central nervous system (somnolence, muscle contraction or spasticity), respiration (respiratory depression). The toxicological properties of this substance have not been fully investigated. Section 12. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The product itself and its products of degradation are not toxic. Section 13. Disposal Considerations Waste Disposal Consult with Local and Regional (State) authorties (waste regulators) to ensure complete and accurate classification. Chemical waste generators must also consult with authorties and determine whether a discarded chemical is classfied as a hazardous waste. Dispose of in accordance with federal, state and local environmental control regulations.

5 L-Carnosine Page Number: 5 Section 14. Transport Information DOT Classification Not a DOT controlled material (United States). Identification Not applicable. Special Provisions for Transport Not applicable. DOT Section 15. Other Regulatory Information and Pictograms Federal and State Regulations California Proposition 65 Warnings Other Regulations TSCA 8(b) inventory: L-Carnosine California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR ). EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No ). Canada: Listed on Canadian Non-Domestic Substance List (NDSL). China: Not listed on National Inventory. Japan: Listed on National Inventory (ENCS). Korea: Not listed on National Inventory (KECI). Philippines: Listed on National Inventory (PICCS). Australia: Not listed on AICS. Other Classifications WHMIS (Canada) Not controlled under WHMIS (Canada). DSCL (EEC) R36/38- Irritating to eyes and skin. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37- Wear suitable gloves. HMIS (U.S.A.) Health Hazard Fire Hazard Personal Protection 2 1 E National Fire Protection Association (U.S.A.) Health 1 Flammability Specific hazard WHMIS (Canada) DSCL (Europe)

6 L-Carnosine Page Number: 6 TDG (Canada) ADR (Europe) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles. Section 16. Other Information MSDS Code References Other Special Considerations C84 Validated by Sonia Owen on 7/6/27. Verified by Sonia Owen. Printed 9/13/27. CALL (31) Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.

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