: Chemtrec (USA/Canada), (Intl)

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1 Revision date: 05/30/2014 : Version: 1.1 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form Product name. : Mixtures : RBC Lysis Buffer Product code : Relevant identified uses of the substance or mixture and uses advised against 1.3. Details of the supplier of the safety data sheet G-Biosciences/ Geno Technology, Inc Page Avenue St. Louis, MO , USA Tel Emergency telephone number Emergency number : Chemtrec (USA/Canada), (Intl) SECTION 2: Hazards identification 2.1. Classification of the substance or mixture Classification (GHS-US) Not classified 2.2. Label elements GHS-US labeling No labeling applicable 2.3. Other hazards 2.4. Unknown acute toxicity (GHS US) No data available SECTION 3: Composition/information on ingredients 3.1. Substances 3.2. Mixtures Name Product identifier % Classification (GHS-US) Deionized water (CAS No) > 90 Not classified Component A < 8 Acute Tox. 4 (Oral), H302 Eye Irrit. 2A, H319 < 1 Not classified < 1 Not classified SECTION 4: First aid measures 4.1. Description of first aid measures First-aid measures general First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact First-aid measures after ingestion : Never give anything by mouth to an unconscious person. If you feel unwell, seek medical advice (show the label where possible). : Assure fresh air breathing. Allow the victim to rest. : Remove affected clothing and wash all exposed skin area with mild soap and water, followed by warm water rinse. : Rinse immediately with plenty of water. Obtain medical attention if pain, blinking or redness persist. : Rinse mouth. Do NOT induce vomiting. Obtain emergency medical attention Most important symptoms and effects, both acute and delayed Symptoms/injuries : Not expected to present a significant hazard under anticipated conditions of normal use Indication of any immediate medical attention and special treatment needed 10/06/2013 EN (English US) 1/5

2 SECTION 5: Firefighting measures 5.1. Extinguishing media Unsuitable extinguishing media : Do not use a heavy water stream Special hazards arising from the substance or mixture 5.3. Advice for firefighters Firefighting instructions Protection during firefighting : Use water spray or fog for cooling exposed containers. Exercise caution when fighting any chemical fire. Avoid (reject) fire-fighting water to enter environment. : Do not enter fire area without proper protective equipment, including respiratory protection. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures For non-emergency personnel Emergency procedures For emergency responders Protective equipment Emergency procedures : Evacuate unnecessary personnel. : Equip cleanup crew with proper protection. : Ventilate area Environmental precautions Prevent entry to sewers and public waters. Notify authorities if liquid enters sewers or public waters Methods and material for containment and cleaning up Methods for cleaning up 6.4. Reference to other sections See Heading 8. Exposure controls and personal protection. SECTION 7: Handling and storage 7.1. Precautions for safe handling Precautions for safe handling 7.2. Conditions for safe storage, including any incompatibilities Storage conditions Incompatible products Incompatible materials 7.3. Specific end use(s) : Soak up spills with inert solids, such as clay or diatomaceous earth as soon as possible. Collect spillage. Store away from other materials. : Wash hands and other exposed areas with mild soap and water before eat, drink or smoke and when leaving work. Provide good ventilation in process area to prevent formation of vapor. : Keep only in the original container in a cool, well ventilated place away from : Keep container closed when not in use. : Strong bases. strong acids. : Sources of ignition. Direct sunlight. SECTION 8: Exposure controls/personal protection 8.1. Control parameters 8.2. Exposure controls Personal protective equipment Hand protection Eye protection Respiratory protection : Avoid all unnecessary exposure. : Wear protective gloves. : Chemical goggles or safety glasses. : Wear approved mask. : When using, do not eat, drink or smoke. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state : Liquid Color : Clear. Odor : None. Odor threshold ph Relative evaporation rate (butyl acetate=1) Melting point Freezing point 10/06/2013 EN (English US) 2/5

3 Boiling point Flash point Self ignition temperature Decomposition temperature Flammability (solid, gas) Vapor pressure Relative vapor density at 20 C Relative density Solubility Log Pow Log Kow Viscosity, kinematic Viscosity, dynamic Explosive properties Oxidizing properties Explosive limits 9.2. SECTION 10: Stability and reactivity Reactivity Chemical stability Possibility of hazardous reactions Conditions to avoid Direct sunlight. Extremely high or low temperatures Incompatible materials strong acids. Strong bases Hazardous decomposition products fume. Carbon monoxide. Carbon dioxide. SECTION 11: Toxicological information Information on toxicological effects Acute toxicity Component A ATE (oral) LD50 oral rat ATE (oral) LD50 oral rat LD50 dermal rabbit Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity (single exposure) Specific target organ toxicity (repeated exposure) Aspiration hazard mg/kg body weight 4220 mg/kg (Rat) mg/kg body weight > 2000 mg/kg (Rat) > 5000 mg/kg (Rabbit) Based on available data, the classification criteria are not met Based on available data, the classification criteria are not met Based on available data, the classification criteria are not met Based on available data, the classification criteria are not met 10/06/2013 EN (English US) 3/5

4 Potential Adverse human health effects and symptoms : Based on available data, the classification criteria are not met. SECTION 12: Ecological information Toxicity LC50 fish 1 EC50 Daphnia 1 LC50 fish 2 LC50 fish 1 EC50 Daphnia 1 EC50 other aquatic organisms 1 LC50 fish mg/l (96 h; Gambusia affinis; Fresh water) 2350 mg/l (48 h; Daphnia magna) 8600 mg/l (96 h; Lepomis macrochirus) 320 mg/l (96 h; Poecilia reticulata; ANHYDROUS FORM) > 100 mg/l (24 h; Daphnia magna) 403 mg/l (3 h; Activated sludge; ANHYDROUS FORM) 1827 mg/l (96 h; Lepomis macrochirus; ANHYDROUS FORM) RBC Lysis Buffer Biochemical oxygen demand (BOD) Chemical oyxgen demand (COD) ThOD BOD (% of ThOD) Biochemical oxygen demand (BOD) Deionized water ( ) Biodegradability: not applicable. Not readily biodegradable in water g O²/g substance RBC Lysis Buffer Log Pow Deionized water ( ) (Estimated value) Bioaccumulation: not applicable. No bioaccumulation data available Mobility in soil Other adverse effects : Avoid release to the environment. SECTION 13: Disposal considerations Waste treatment methods Waste disposal recommendations : Dispose in a safe manner in accordance with local/national regulations. Ecology - waste materials : Avoid release to the environment. SECTION 14: Transport information In accordance with ADR / RID / ADNR / IMDG / ICAO / IATA UN number UN proper shipping name 10/06/2013 EN (English US) 4/5

5 14.3. Additional information : No supplementary information available. Overland transport Transport by sea Air transport SECTION 15: Regulatory information US Federal regulations International regulations CANADA EU-Regulations Classification according to Regulation (EC) No. 1272/2008 [CLP] Classification according to Directive 67/548/EEC or 1999/45/EC Not classified National regulations US State regulations SECTION 16: Indication of changes : Revision - See : *. : None. Full text of H-phrases: see section 16: Acute Tox. 4 (Oral) Acute toxicity (oral) Category Eye Irrit. 2A Serious eye damage/eye irritation Category 2A H302 Harmful if swallowed H319 Causes serious eye irritation SDS US GENO (GHS HazCom 2012) This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product 10/06/2013 EN (English US) 5/5