Creating Water Solutions for the Pharmaceutical Industry

Transcription

1 Creating Water Solutions for the Pharmaceutical Industry

2 Creating Water Solutions for the Pharmaceutical Industry Water is an essential component for the pharmaceutical industry Water is the most common used liquid in the pharmaceutical industry, not only as an ingredient in many formulations, but also as a cleaning agent. The production of Purified Water, Highly Purified Water and Water For Injection to international pharmaceutical standards is widely recognised as a critical process. Veolia Water Solutions & Technologies has a wealth of experience in the pharmaceutical market and offers solutions based on packaged or engineered systems. We cover the full water cycle in a pharmaceutical manufacturing facility, from process water to wastewater. > Pharmaceuticals > Biotechnology > Healthcare > Cosmetics > Contact Lenses > Research Facilities > Veterinary Products As a world leader in creating water solutions, we use the latest technologies available to improve manufacturing efficiency without compromising process security and product quality. All aspects of our product development, project management and service offerings are managed to the highest quality standard to ensure that our dedicated team of experts are in tune with your needs. We deliver complete water treatment solutions that meet and exceed these standards through compliance with: > Latest USP, JP and Ph Eur (United States, Japanese and European Pharmacopoeia standards) > ISPE (International Society for Pharmaceutical Engineering) > cgmp (current Good Manufacturing Practice) > GAMP (Good Automated Manufacturing Practice) > CE marking > IPCC environmental requirements (Intergovernmental Panel on Climate Change) > FDA requirements (US Food and Drug Administration) All of our products, services & activities are certified to AS/NZS ISO 14001, AS/NZS ISO 9001 and AS/NZS 4801 by BSI Certification.

3 Innovative Water Solutions Orion II - Purified Water World leading water purification package with more than 80 standard options, producing from 500 to 10,000 L/hour of purified water Guaranteed microbial compliance through regular hot water sanitisation at 85 C Multi-Technology System: Activated Carbon + Reverse Osmosis + Continuous Electrodeionisation + UV + Ultrafiltration NEW MODEL Quattro -S - Purified Water A fully integrated water purification package for the pharmaceutical industry, meeting USP and Ph Eur purified water specifications Cost-effective solution for supplying up to 3,000 L/hr of high purity water (less than 0.7μS/cm conductivity) Skid mounted design combining: Softening + Filtration + Reverse Osmosis + Continuous Electro Deionisation Chemical sanitisation for microbial control No regeneration chemicals IonPro LX - Purified Water Can produce from 500 to 1,000 L/hr (2.2 to 4.4 gpm) of multimegohm high purity water Units can be connected directly to the mains water supply and produce high purity, bacteria-free water to feed a ring main or a storage tank Combines Reverse Osmosis + Continuous Deionisation Minimal footprint (compact, portable cabinet), automatic sanitisation and low noise operation NEW MODEL Triton - Purified Water A compact purified water system Unique packaged system combining production, polishing, storage tank & distribution Combines reverse osmosis, continuous deionisation and UV with optional ultrafiltration Designed to meet USP + Ph EUR Purified Water and Ph EUR Highly Purified Water Requirements Applications: production of clinical trial material, scale-up from research to production, pilot trials, small volume specialist products, large scale research products Polaris - Water For Injection Range includes Multi-Effect Distiller (Polaris MED), Vapour Compression Distiller (Polaris VCD) and Clean Steam Generator (Polaris CSG) An efficient and effective pyrogen removal solution for water for injection Designed to GAMP, cgmp, ISPE and FDA guidelines and meets quality specifications of USP, Ph Eur Comprehensive range of service maintenance products, including specific parts and consumables Hydrex Specialty Water Treatment Chemicals A complete range of water treatment chemicals for boilers, cooling towers, membranes or wastewater installations Can significantly improve the management of scaling, corrosion, suspended solids & reduce operation & maintenance costs NEW MODEL Specialty Water Treatment Chemicals for OPTIMUM Plant Performance Contact us to know more about our Healthcare Water Treatment Solutions Access our brochures on and

4 Rapide Strata Deionisation Systems - High Quality Water Produce high quality water for healthcare and pharmaceutical applications Unique design offering up to 40% savings on running costs Short Cycle Ion Exchange technology enhancing bacterial control and maximising production time Reduced treated water storage costs Highly efficient use of chemical regenerants Small footprint Moving Bed Biofilm Reactor (AnoxKaldnes MBBR ) Innovative biological solution with a compact footprint and low energy consumption to treat difficult wastewaters (high BOD/COD), with minimal sludge production Combining the advantages of activated sludge and fixed biofilm systems Very flexible system, easy to operate and can easily be installed in existing tanks or basins (more than 500 installations worldwide) Biothane Highly efficient, cost effective biological methods to reduce pollution and recover energy with a minimal environmental impact Biothane UASB and Biobed EGSB processes use anaerobic bacteria growing in a granular matrix without use of any carrier materials The anaerobic process enables removal of COD by converting it into biogas (= methane + carbon dioxide) at low operational costs and with a very compact plant design No waste sludge production Applications 1. Purified water 2. Highly purified water 3. Water for injection 4. Wastewater 5. Reuse, Reclaim & Recycle Maintenance & Service It is important that once the water treatment plant is installed that regular service and maintenance is applied. We can implement a detailed operating and maintenance program to ensure that the plant works efficiently without any issue. Customer Care The pharmaceutical industry is one of the most demanding in the world. Veolia Water Solutions & Technologies, as a total service company, understands that it s not just about our equipment complying with GMP, but also how we document what we do and ensure regulatory compliance. Our service starts with professional project management and a comprehensive validation methodology. Validation is built into our contract management and service philosophies. Our in-house team of specialists prepare the essential documents needed to support the installation, commissioning and maintenance of your water systems. Our skid mounted water systems are designed to GAMP and GMP as a standard. Our proven validation package significantly reduces site installation and validation time, helping to minimize costs and shorten lead times. We offer a variety of flexible, cost-effective service contracts with short guaranteed response times to minimize your downtime. And we provide Hydrex Specialty Water Treatment Chemicals as well as parts from strategic spares to membrane replacements when you need them.

5 Purified Water Treatment Plant & Servicing, Astra Zeneca - NSW > Providing Reverse Osmosis, Continuous Deionisation equipment and water softeners for the Purified Water Treatment Plant > Treated water is used for making distilled water and pure steam used in water for injection > Providing Hydrex Specialty Water Treatment Chemicals to cooling towers, chillers and boilers to ensure long term efficiency & operation of the equipment Quattro -S Purified Water Generation Plant, Probiotec Pharmaceuticals - VIC > Design, supply, commissioning and validation of the Purified Water Generation system > Treat municipal town mains water to meet Purified Water Standards for use in pharmaceutical products > The total treatment package includes a Quattro -S unit featuring media filtration, cartridge filtration, softeners, activated carbon, reverse osmosis, CEDI and UV Orion Purified Water Generation System, CSL - VIC > Design, supply, installation, commissioning and operator training of two Orion units with pre-treatment > The Orion units will treat municipal town mains water to Purified Water Standards to meet the needs of the pharmaceutical industry > Hydrex chemicals will also be supplied on an ongoing basis to ensure long-term efficiency of operation Water For Injection Plant, Pharmaxis - NSW > Supply of a Water For Injection plant, including pre-treatment station, chlorine and Polaris VCD > Capacity: 750 L/hr & 560 L/hr > Treats drinking water for the manufacture and packaging of inhalants for supply to the European market > Technologies: multimedia filtration, activated carbon, reverse osmosis and continuous deionisation, followed by Polaris VCD (Vapour Compression Distiller) > The new reverse osmosis and continuous deionisation units will expand the current production rate without increasing the current plant footprint Anaerobic Plant for Biological Treatment, Roche Diagnostics - Germany > Supply & installation of an anaerobic plant for the biological pre-treatment of partial wastewater flows rich in carbon as well as biologically degradable liquid waste from the bio-technological production > Technology: 480 m 3 Biobed EGSB reactor (Expanded Granular Sludge Bed) > Energy-rich biogas produced by the process will be used to produce energy that will cover more than 90 per cent of the wastewater treatment plant energy requirements > Carbon dioxide emission will be reduced by about 950 metric tons per year Wastewater Treatment Plant, Astra Zeneca - Sweden > Treat complex and highly toxic wastewater with difficult to degrade organic compounds from pharmaceutical production for environmental discharge into a sensitive environment > The wastewater is completely detoxified, using microfungi - overall TOC removal is 97%, 80% nitrogen removal and 99% phosphorous removal. > New wastewater treatment plant using a three-stage MBBR biological treatment process, followed by chemical phosphorous precipitation and polishing with activated carbon and a sand filter > Flow: 1,800 m 3 /d. Average incoming TOC: 440 kg/day

6 Veolia Water Solutions & Technologies Australia and New Zealand Creating Water Solutions Veolia Water Solutions & Technologies is a world leader in Design & Build of water and wastewater treatment plants. We specialise in delivering world-class solutions to all your pharmaceutical process water & waste water needs. We are committed to providing water treatment systems and services to the Pharmaceutical, Biotech, Healthcare and Cosmetics sectors. With over 80 years water treatment experience, our focused approach and in-depth knowledge, backed by exemplary customer service, means we can expertly guide your business by delivering pharmaceutical water solutions that meet your needs, giving you peace of mind every time. Sydney Unit 2, 5 Stanton Road Seven Hills NSW 2147 Ph: Fax: Melbourne 341 Fitzgerald Road Derrimut VIC 3030 Ph: Fax: Perth 124 Kewdale Road Kewdale WA 6105 Ph: Fax: Brisbane 5/26 Navigator Place Hendra QLD 4011 Ph: Fax: Adelaide 500 Churchill Road Kilburn SA 5084 Ph: Fax: Darwin 5 Dennis Court Berrimah NT 0828 Ph: Fax: New Zealand Level 3, Parnell Rd Parnell, Auckland 1052 Ph: Fax: nzsales@veoliawater.com Veolia Water Solutions & Technologies Australia Level 4, Bay Centre, 65 Pirrama Road Pyrmont NSW 2009 Australia Ph / Fax systems@veoliawater.com Veolia Water Solutions & Technologies is a company of Veolia Environnement, Creating Water Solutions for the Pharmaceutical Industry - November 2010 Veolia Water Solutions & Technologies, All rights reserved.