Research in progress (housing & malaria)

Transcription

1 Wednesday 7 February 2018 Research in progress (housing & malaria) Professor Steve Lindsay, Durham University, UK

2 Overview: 1. WHO policy documents 2. Recent research on risk 3. Development of new interventions Eaves tubes 2

3 Health policy on housing 3

4 1. Global Vector Control Response

5 2. WHO Policy document from Department of Public Health, Environmental and Social Determinants of Health 5

6 Research on risk 6

7 3. Malaria and house design in rural Uganda

8 Malaria and house design in rural Uganda Rapid improvements in house design were observed in a cohort of households in rural eastern Uganda from After malaria transmission was reduced by a mass IRS campaign, modern housing was associated with additional reductions in mosquito density (73% lower) and parasite prevalence (57% lower), compared to traditional homes. Conclusion: housing improvements may add benefit alongside primary interventions. Out on February 9 th 2018 in The Lancet Planetary Health lucy.tusting@well.ox.ac.uk 8

9 4. New house designs 9

10 4. New house designs 10

11 4. New house designs Reductions in malaria vectors 96% (95% CIs = 92-98%) in double-storey buildings 77% (95% CIs = 72-82%) in single-storey buildings 23% (95% CIs = 18-29%) in control buildings 11

12 5. Relative attractiveness of African houses Ebrima Jatta

13 80-100% malaria transmission in sub- Saharan Africa occurs indoors Huho et al. Int J Epidemiol 2013; 43:

14 Experimental houses on village edge

15 Experimental houses Experimental houses, Wellingara

16 Latin Square design Week House position Metal roof Thatched, closed eaves, screened doors 2 Thatched, closed eaves, screened doors Thatched roof, closed eaves Thatched, open eaves Thatched roof, closed eaves RooPfs Metal roof RooPfs Thatched, open eaves 3 Thatched roof, closed eaves RooPfs Thatched, closed eaves, screened doors Thatched, open eaves Metal roof 4 RooPfs Thatched, open eaves Thatched roof, closed eaves Metal roof Thatched, closed eaves, screened doors 5 Thatched, open eaves Metal roof RooPfs Thatched, closed eaves, screened doors Thatched roof, closed eaves

17 Moving roofs

18 Mean no. mosquitoes/house/night Small changes to rural houses can be protective against malaria vectors 25 Female An. gambiae s.l Thatched roof, open eaves, unscreened doors Thatched roof, closed eaves, unscreened doors Thatched roof, closed eaves, screened doors House typology Metal roof, closed eaves, unscreened doors Ventilated-metal roof, closed eaves, screened doors

19 Changing temperatures Night Night Day Day

20 0:00 1:00 2:00 3:00 4:00 5:00 6:00 7:00 8:00 9:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 20:00 21:00 22:00 23:00 Temperature ( o C) Indoor temperatures in different Gambian houses Outdoor temperature

21 Carbon dioxide (ppm) 1' Metal roof Thatch roof :00 22:00 23:00 0:00 1:00 2:00 3:00 4:00 5:00 6:00 time

22 Development of interventions 22

23 6. Development of new screened doors Intellectual Ventures, Global Good Fund, Bellvue, USA

24 Evolution of the door Gambian Francophone RooPfs Concertinaed

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26 New screened, self-closing doors Control D1 D2 D3 D4 Designed by J. Knudsen & Global Good

27 Other mosquitoes s.l./house/night Reduction in nuisance mosquitoes entering houses Control All GG doors N = 6 N = Weeks

28 7. Eaves tubes Marit Farenhorst reporting progress with the Eave tube trial later 28

29 Thank you, find out more visit RBM Partnership to End Malaria 3rd floor, TCS Building, Chemin de Blandonnet 2, 1214 Vernier, Geneva, Switzerland. 29