PHARMA IMPRESSIONS. Packaging Solutions Newsletter 02 / 16 INEXPENSIVE INNOVATIONS, CONSTANTIA COLDFORM RESIST AND THE CONSTANTIA 3D BLISTER

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1 Pharma PHARMA IMPRESSIONS Packaging Solutions Newsletter 02 / 16 INEXPENSIVE INNOVATIONS, CONSTANTIA COLDFORM RESIST AND THE CONSTANTIA 3D BLISTER Constantia Flexibles had an excellent start in the new year, receiving no less than three Alufoil Trophies from the European Aluminum Foil Association. The awards were given in the areas of Customer Convenience, Product Protection and Resource Efficiency. We are very proud to be among the winners. This recognition highlights the way in which Constantia Flexibles combines the advantages of aluminum foil with innovative ideas in order to improve existing products, says CEO Alexander Baumgartner. The CONSTANTIA Blister Eco was awarded in the Resource Efficiency category. CONSTANTIA Blister Eco consists of tissue paper lined with a thin aluminum layer, which makes it 23% lighter than standard blister lidding foils. The aluminum content of the product is now only about 40%. In comparison, standard blister lidding foils have an aluminum content of roughly 90%. Alongside the prize winners, Constantia Flexibles also has two newcomers: CONSTANTIA Coldform Resist and CONSTANTIA Coldform Resist the CONSTANTIA 3D Blister. With CONSTANTIA Coldform Resist, Constantia offers a new laminate on the market that can also withstand very aggressive solvents and products such as ethanol and acetone. It also forms a reliable barrier against moisture, oxygen and other gases. In addition, it is very easy to form and the layer of the laminate can be customized for the respective product. The CONSTANTIA 3D Blister, another new product, is directed primarily at patients who suffer from reduced dexterity due to illness or age. With this new system, the pills are very easy to press out of the packing, even for the first time with one hand; and they do not fall easily to the floor. It also allows for better presentation of the Patient Information Leaflet. CONTENT Editorial Fairs and Events News Investments

2 SPAIN A DIFFERENTIATED VIEW OF THE PHARMACEUTICAL MARKET EDITORIAL From a global point of the view, the Spanish market for pharmaceutical products was the tenth largest worldwide in the year 2013 by turnover in USD. As in so many other countries, the population in Spain is getting older and therefore also more prone to health problems. Chronic illnesses are an important factor here, plus the fact that the costs for those treatments for which the health insurance institutions no longer reimburse the whole amount are growing accordingly. The market for products in the Consumer Healthcare sector is also on the rise. There are two reasons for this, which also influence this market segment: on the one hand there is a growing trend towards self-medication in Spain, and on the other hand some medicines and treatments are no longer paid for by the state health care system. There are also other factors at work on the market: an increasing number of generics being prescribed, cutbacks in spending on pharmaceutical products, and governmental control of the pharmaceutical budget at a central and regional level. A glance at the relevant figures shows that expenditure on pharmaceutical products declined between 2010 and The reason for this was new legislation in the wake of the economic crisis, with which the government enforced a reduction in the price of pharmaceutical products in the public sector in the years 2010 and Combined with the already reduced pharmaceutical budget, this led to the market volume shrinking by more than six percent a year. Sales went down even further in the year 2012 due to further cutbacks. Following a stable 2013, sales picked up again in the year 2014, and last year they stood at around EUR 18,500 million. An important fact, however, is that the generics market increased over the entire period. Here too it is worth taking a closer look, because while the proportion of branded products in the pharmaceutical sector declined by 18.4 percent in the last four years, the proportion of generics rose by 45.9 percent. In the meantime, generics account for 40 percent of the packaging units sold, a trend which will continue in the years to come, and that will mean even greater pressure on prices. I hope I am not exaggerating when I write that we have once again assembled an issue for you that is chockful of interesting information. Before we take a look at the exciting topics, however, I would like to introduce two new employees in Marketing: the Head of Marketing, Klaas Nemitz, and Omar Abdel-Galil, our new Marketing & Communication Manager Pharma. This division of the duties into two positions also reflects the new structure and organization of the Pharma Division. We are pleased to welcome both of them! Another exciting development is that Constantia Flexibles was recognized this year with three Alufoil Trophies, two of which went to the Pharma Division. This is a great success that motivates us to continue doing what we do best: develop innovations in cooperation with our customers. In the article about our prizewinning products, you can also learn about two other innovative products: the CONSTANTIA 3D Blister and CONS- TANTIA Coldform Resist. Plus: We have been on the road again. First to one of our own events, the well-known Customer Academy, and then to the Pharmazing Days However different these events are, one thing always remains the same: The discussions with customers, partners and colleagues promote progress and offer enjoyable experiences for those involved. Finally, I would like to recommend our look at the Spanish market. The article about our new investments in northern Spain will definitely also be of interest. We have increased our capabilities here with a new narrow-width printing machine as well as a narrow-width adhesive lamination machine. I trust you will find this newsletter an interesting and thought provoking read. Source: Flickr/farm3 Pierre-Henri Bruchon Executive Vice President Pharma Division

3 FAIRS AND EVENTS DISCUSSIONS WITH CUSTOMERS INTENSIVE AND INTERNATIONAL The Customer Academy has become an integral part of daily life at Constantia, simply because the best ideas often come about during lively and open discussions. It was held not once but twice last April: Under the motto Customer Academy goes East in Bad Erlach near the Constantia Patz site and at AstraZeneca in Södertälje, Sweden. The Customer Academy was held for the second time at AstraZeneca, once again bringing together almost 60 employees from many different areas, such as Packaging Development, Global Operations Procurement and Production. All participants agreed that the Academy was a complete success, says Omar Abdel-Galil, Marketing & Communication Manager at Constantia. The atmosphere was great, we were able to answer a lot of questions, and we are now planning a new Customer Academy in the United Kingdom to follow this meeting. The resonance was no different in Bad Erlach here, too, around 100 participants from 70 different customers and partners from Eastern Europe were very satisfied. The main focus this time was on technical content combined with a plant tour at Constantia Patz. What was especially popular during the event was the "Marketplace," where partners could display their products and services and network with the other attendees. Another hot topic was the serialization of pharmaceutical products. Customer Academy goes East (Bad Erlach) and Customer Academy AstraZeneca (Södertälje)

4 NEWS NEWS FROM THE MARKETING DEPARTMENT! We are delighted to introduce two new employees in the Pharma Division of Constantia Flexibles: Klaas Nemitz as the new Head of Marketing and Omar Abdel-Galil, who will be taking on the position of Marketing and Communication Manager Pharma. These two employees represent a significant reinforcement of our Marketing Department. They will help Marketing become more strategic nal orientation and is also growing rapidly. Omar Abdel-Galil also brings with him the right know-how in this area thanks to his work at a major pharmaceutical manufacturer. Omar also has a good reason for switching to Constantia: Constantia is a company that is positioning itself globally. This creates new challenges and new possibilities. I am excited to be a part of this. THE SUMMIT In April, Uhlmann issued an invitation to their three-day Summit", also known as Pharmazing Days 2016, and the pharmaceutical division of Constantia Flexibles was there as well. This was an invitation that we gladly accepted. The interaction with our customers as well as more customer-oriented than before. Klaas Nemitz has the necessary experience for his new position as Head of Marketing. Klass has previously worked as Marketing Manager International Marketing, Brand Equity Manager and Senior Brand Manager at major companies. I am especially looking forward to working at Constantia because the company has a strong internatioand partners is very important to us and at the same time something we live everyday in our business. The meeting requests sent to us and the large number of visitors at our booth indicated that the industry is looking to communicate with us. Ideas and future projects were discussed with both well-known and new partners. This also succeeded so well because the framework was right: 13 expert presentations, 35 international exhibitors and approximately 1,000 industry experts and leading decision-makers were there. Last but not least, the new Uhlmann hall also has to be praised, as it provided a most appropriate setting for the Pharmazing Days. Pharmazing Days 2016

5 Pharma HOW CONSTANTIA FLEXIBLES SERVES THE MARKET S NEEDS Constantia Flexibles is spending a lot of money : the production capacities at the site in Burgos, Northern Spain, are being expanded. The total investment amounts to approximately four million euros. The efforts are centered primarily on a new narrow web short-run printer and a narrow web adhesive lamination machine. The market environments have changed rapidly. Requirements for short run services have risen steadily recently and will continue to rise in future. The reasons are obvious: new product launches, sampling, market tests, promotions, et cetera. As a result, Constantia Flexibles has decided to invest in the printing and lamination technologies that has been successfully used in our plant for decades. This short run offer allows dedicated customer service that satisfies specific requirements and provides speedy delivery. The site in Burgos belongs to Constantia Tobepal, which has been serving customers for more than 80 years primarily with foil-based flexible packaging for the pharmaceutical, home and personal care and the food industries. In total, Constantia Tobepal employs about 500 people at its two production sites in Burgos and Logrono in Spain. This investment not only increases our operational efficiency due to its focus on short run batches, but also emphasizes our clear commitment to always propose to our partners the most reliable and "agile" offer, said Gerold Riegler, Chief Operating Officer at Constantia Flexibles, about the investment. CONTACT Published by: Constantia Flexibles International GmbH Pharma Division Rivergate, Handelskai Vienna/Austria T Pharma@cflex.com Personalcare@cflex.com LATE-BREAKING NEWS The Constantia Flexibles Group is to acquire the Vietnamese manufacturer of pharmaceutical packaging Oai Hung Co. Ltd. The acquisition, subject to approval from appropriate competition and regulatory authorities, is expected in the coming months. Oai Hung is focused in particular on supplying blister foils of aluminum, coldform foils and various plastic films to the growing regional pharma industry... You can read more about this new investment by Constantia Flexibles in the next issue. 06_2016