Master in Molecular Life Sciences (MLS) Why doing a master? Fills an important gap between the mostly theoretical background that you acquired during your BSc and skills that you need for many professional careers. 2 1
Why choosing the MLS? Because you love: Biology Doing experiments Understanding how it works 3 Why choosing the MLS? You will acquire essential soft-skills such as presentations in written & oral forms, teamwork, time management, work in an international environment You will learn how to synthesize information. You will learn how to identify interesting questions and find ways to address those questions using either experimental or computational methods. You will be exposed to the genomics revolution. 4 2
How will you acquire those skills? Research Design and perform your research English in your working environment Less ex cathedra teaching, more involvement from the students Write a scientific assay and a research proposal Handle lab work and coursework (prioritize, organize) 5 The program on one slide Semester 1 (7) Common courses Optional courses 1st step project Exams Semester 2 (8) Common courses Optional courses Exams Master project Semester 3 (9) Defense of the Master project 6 3
Start with a two-day retreat To help you selec>ng op>onal courses and a topic for "write a review" course. To learn about research performed in the different departments. Presenta>on from industry (2010 Novar>s; 2011 Nestlé; 2012 Debiopharm; 2013 AGIRE; 2014 Changins; 2015 Selexis; 2016 Pharmalp) Meet and integrate new students. Discuss with previous master students. 7 Common courses «Sequence a genome» 1) Sequence and assemble new genomes (semestre 1) 2) Annotate and compare these genomes with others (semestre 2) A teamwork to learn different aspects of genomics and bioinforma6cs «Write an applica>on for a research fellowship» 1) Write a review in groups of 3 with a tutor (semester 1) 2) Write a fellowship applica>on with a tutor (semester 2) Learn to read papers, extract informa6on and write scien6fic text 8 4
Sequence a genome 2016-17 Bumble bee Gut microbiota Lactobacilli Firm-5 Philip Engel, Jan van der Meer 9 A unique course in Europe & the world 1 0 5
Students have published their work from «sequence a genome» 1 1 Write a Review & Fellowship Request Teaches important wri>ng skills that will be useful for various reports during the master & later in your career. Helps you understanding your master project Can lead to a publica>on or a PhD fellowship 1 2 6
A large variety of op>onal courses Including the possibility to select up to 3 credits from the BEC 1 3 Common themes in the MLS master We study life at all levels from molecules to ecosystems. A proper understanding of biological ques>ons oden requires a mul>-level analysis Despite the variety of ques>ons, organisms and approaches some of the underlying methods and theory are very broadly relevant. 1 4 1 4 7
Use the latest technologies such as UHTsequencing, CRISPR Model systems Clinical research Microbial, animal and plant genetics GTF platform K. Harshman 1 5 Bioinforma>cs Biology needs more and more bioinformatics Career prospects 1 6 8
Three Men>ons in the MLS master Bioinforma>cs Integra>ve Biology Microbiology 1 7 Research during your Master 1st step project in one laboratory (semester 1) Master project in another laboratory (semester 2 and 3) 1 8 9
Exci>ng research opportuni>es in https://www.unil.ch/eb-mls/home/menuguid/host-laboratories.html 1 9 Basic Research & Biotechnology Animal and medical biology: Nicolas Mermod (IBT) Gene therapy (muscular dystrophy) Plant biology: Yves Poirier (DBMV) Microbiology: Jan Roelof van der Meer (DMF) Biosensor 2 0 1 0
Exci>ng research opportuni>es at: CIG Centre Intégratif de Génomique IBT Institut de Biotechnologie IMUL Département de Biologie Computationnelle Institut de Microbiologie CHUV Institut Suisse de Bioinformatique Department of Ecology and Evolution 2 1 Check out research porfolios on: hgps://www.unil.ch/dbmv/en/home/menuinst/recherche.html hgps://www.unil.ch/dmf/en/home/menuinst/research-units.html hgps://www.unil.ch/cig/en/home/menuinst/research/researchgroups.html hgp://www.chuv.ch/microbiologie/imu_home/imurecherche.htm hgps://www.unil.ch/dee/home/menuinst/research.html hgps://www.unil.ch/dgm/home/menuinst/research-groups.html 2 2 11
Do you need more informa=on? Apéro in the hall of the Génopode star>ng at 1700 hgps://www.unil.ch/eb-mls/en/home.html Chris>an.fankhauser@unil.ch 2 3 Overview Microbiology Aim: study a wide range of advanced topics in microbial sciences Requirements: 12 ECTS credits of op>onal courses in microbiology first semester all compulsory: acquire basics of bioinforma>cs Master project in microbiology 1 2
Microbiology Classes Advanced Microbial Gene>cs (LIT) Bacterial Genomes and Genome Evolu>on (WEB, EXERCISES) Fungal Virulence and Pathogenicity (LIT) Immunology with Relevance to Infec>ous Diseases (LIT) Virus-Host Interac>ons (LIT) An>-Infec>ve Agents (LIT) Bacterial Virulence and Pathogenesis (LIT) Cytoskeleton from Microbes to Man (EXERCISES) Epidemiology (LIT) Microbes as Tools in Experimental Biology (LIT) Microbial Ecology (TP) Viral Pathogenesis and Emerging Viruses (LIT) (Synthe>c biology, chromosome structure, more to come) Overview Bioinformatics Aim: biologist-bioinforma>cian bioinforma>cian in experimental lab biologist using both bioinforma>cs and experiments Requirements: first semester all compulsory: acquire basics of bioinforma>cs both projects in bioinforma>cs first step purely bioinforma>cs master project mostly bioinforma>cs can be hosted by bioinforma>cs or experimental lab 1 3
Compulsory courses in Autumn Case studies in Bioinformatics Programming (Python) Advanced Data Analysis in Biology I-II Tuesday 7 March 17 Titre de la présentation 27 Optional courses in Spring Industrial bioinformatics Bioinformatic Algorithms Phylogeny and comparative methods Quantitative genetics Tuesday 7 March 17 Titre de la présentation 28 1 4