Curriculum for the Bachelor Degree in Biotechnology

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The curriculum for the B.S.c. degree in is (15) credit hours are distributed as follows:- No. 1 2 4 Requirements University Requirements Compulsory Elective Faculty Requirements Specialization Requirements Compulsory Elective Supportive Specialization Requirements Total Credit Hours 21 6 26 64 6 12 15

First : University Requirement (24 Cr.H.) A: Compulsory Requirements (21 Cr.H.): Course No. 500101 500102 5004101 5004102 5005101 5001101 5002100 Course Title Arabic (1) Arabic (2) English (1) English (2) Computer Skills (1) Military Sciences National Education Cr.H. Weekly Hours Lecture Lab. -- -- -- -- 2 -- -- Prerequisite -- 500101 -- 5004101 -- B: Elective University Requirements : (6 Cr.H.) The student is allowed to select (6 Cr.H.) from the university elective courses offered by faculties other than the faculty of Agricultural Technology. Course No. Course Title Cr.H 6001101 Communication skills 6002102 Introduction to Psychology 60010 Jordanian Society 6004104 Sport for All 6005105 Islamic Culture 6006106 Administration and Economic Concepts 6007107 Agriculture in Jordan 6008108 Environment and Society 6012109 The Orthodox Caliphs History

Second: Faculty Requirements: (26 Cr.H.) Course No. Course Title Cr.H. 0202101 Calculus (1) 0404151 General Biology (1) 0404152 General Biology (2) 040415 General Biology Lab (1) 1 0404154 General Biology Lab (2) 1 0206101 General Chemistry (1) 020610 General Chemistry (2) 0206102 General Chemistry - Lab 1 (1) 0206104 General Chemistry Lab 1 (2) 020110 Physics for Agricultural students 0201104 Physics for Agricultural 1 students Lab 5005102 Computer Skills (2) * Prerequisite Weekly Hours Lecture Lab. 0 0 0 0 0 0 0 0 0 0 0 2 Prerequisite --- --- 040415 0404151* 0404152* --- 0206102 0206101* 020610* --- 020110* 5005101 Third: Specialization Requirements: (70Cr.H. ) A- Compulsory Requirements: (64 Cr.H.) Course No. Course Title Cr. H. Weekly Hours Prerequisite Lecture Lab 0402221 Microbiology 2 0404154 0402 Plant Physiology 2 040211 040412 Plant Tissue Culture 2 0402 04041 Plant 0 0402 040421 General Genetics 2 0404154 040424 Biostatistics 0 0202101 04041 Cell Biology 0 0404154 04042 Molecular Biology 2 04041 04044 Animal Physiology 2 0404154 0404401 Field Training 6 0 0 ----- 0404402 Seminar 1 1 0 ----- 040440 Graduation Project 0 0 ----- 0404411 Food 0 020622

Course No. Course Title Cr. H. Weekly Hours Prerequisite Lecture Lab 0404414 Animal 0 04044 0404422 Microbial Genetics 0 0402221 040442 Molecular Genetics 0 04042 04044 Genetic Engineering 2 04042 040444 Bioinformatics 0 04042 0404441 Immunology 0 020622 0402221 0404442 Virology 2 020622 0404444 Microbial 0 0402221 Every three credit hours equal (140 hours) field training B: Elective Specialization Requirements: (6 Cr. H.) to be selected from the following list: Course No. Course Title Cr. H. Weekly Hours Prerequisite Lecture Lab 040121 Principles of Environmental 0 ----- Science 040251 Principles of Plant Protection 0 ----- 04071 Principles of Agricultural 0 ----- Extension 040415 Environmental 0 0402221 040445 Biosafety 0 04042 0404445 Special Topics 0 04041 Fourth: Supportive Specialization Requirements : (12 Cr. H. ) Course No. Course Title Cr. H. Weekly Hours Lecture Lab Prerequisite 040211 Principles of Plant Production 0 040415 0206221 Organic Chemistry 2 020610 0206241 Analytical Chemistry 2 020610 020622 Biochemistry 2 0206221

First semester First Year Second Semester Course No. Course title Cr. H. Course No. Course title Cr. H. 500101 Arabic 1 500102 Arabic 2 5004101 English 1 5004102 English 2 5005101 Computer Skills (1) 0202101 Calculus (1) 0404151 General Biology (1) 0404152 General Biology (2) 040415 General Biology -Lab (1) 1 0404154 General Biology -Lab 1 (2) 0206101 General Chemistry (1) 020610 General Chemistry (2) 0206102 General Chemistry-Lab (1) 1 0206104 General Chemistry-Lab 1 (2) Total 17 Total 17 First semester Second Year Second Semester Course No. Course title Cr. H. Course No. Course title Cr. H. 5005102 Computer Skills (2) 040211 Principles of Plant Production 020110 Physics for Agricultural 0402221 Microbiology Students 0201104 Physics for Agricultural 1 5002100 National Education Students-Lab 0206241 Analytical Chemistry - Elective Specialization Requirement 0206221 Organic Chemistry - Compulsory University 5001101 Military Sciences Requirement Total 16 Total 15

First semester Third Year Second Semester Course No. Course title Cr. H. Course No. Course title Cr. H. 020622 Biochemistry 04041 Plant 040424 Biostatics 04042 Molecular Biology 04041 Cell Biology 04044 Animal Physiology 04022 Plant Physiology 0404422 Microbial Genetics 040421 Genetics 0404444 Microbial 0404411 Food Elective Specialization Requirement Total 18 Total 18 First semester Fourth Year Second Semester Course No. Course title Cr. H. Course No. Course title Cr. H. 040412 Plant Tissue Culture 0404414 Animal 0404442 Virology 0404441 Immunology 040442 Molecular Genetics 04044 Genetic Engineering Compulsory University 040444 Bioinformatics Requirement 0404401 Field Training 6 040440 Graduation Project 0404402 Seminar 1 Total 18 Total 16

Al-Balqa Applied University Course Description 500101 Arabic Language 1 (-0) This course contains a set of linguistic skills in different levels such as the sounds of the Arabic language, its morphology, syntax, rhetoric, lexicography and writing. It includes as well as on applications on the use of Arabic dictionaries and applications on some writing skills indispensable for scholars in their working lives. It also contains a refined set of Quranic, poetry and short stories of Arabic texts to give the learners the opportunity to be in contact with and to appreciate these texts. Pre-req. Arabic 99 or passing Arabic Level Exam 500102 Arabic Language 2 (-0) This course aims to develop student's skills in writing and expression and to provide him with the necessary and basic ones in order to employ them in his daily use, and enable him to stand on the origins of various Arabic scripts, and access to various forms of technical and functional old and new writing. Pre-req. 500101 5004101 English 1 (-0) Is a complete graded course for foreign learners of English; it covers the skills of listening, speaking, reading, and writing; as well as improving pronunciation and building vocabulary; particular emphasis is placed on listening and speaking; the language of the course is British English. Pre-req. English 99 or passing English Level Exam 5004102 English 2 (-0) Is a continuation of English I Course in terms of approach and methodology However, it covers a new range of interesting topics, and provides a more advanced grammar syllabus in a communicative context as well, therefore, this topic tends to be a continuation of ENGL 101 goals. Pre-req. 5004101 5005101 Computer Skills 1 (0-6) An introduction to computing and the broad field of information technology. Topics covered include the basic structure of digital computer systems; operating systems; application software; data communication and networks; and the Internet hands-on learning emphasizes windows (latest operating systems); MS- Office; and the Internet. 5001101 Military Science (-0) This course aims at providing university students with general military culture and illustrating the overall military capabilities of the armed forces to defend the homeland and its role in development and service of the Jordanian society through lectures and field visits. 5002100 National Education (-0) The course of National Education is one of the compulsory requirements of all students in Jordanian universities, national and private. The general intent is to provide students with the theoretical and practical knowledge of the homeland (Jordan), land and people, and to consolidate the love of the homeland and national brotherhood in them, to motivate them to serve the nation and the people consciously and sincerely, to be innovative and competitive by exhortations to achieve the desired progress in various fields of life. 0202101 Calculus (1) (-0) Functions: domain, operations on functions, graphs of functions, trigonometric functions; limits and continuity; the derivative: techniques of differentiation, the chain rule, implicit differentiation; differentials; Roll's theorem; the main value theorem; L'Hôpital's rule; increasing and decreasing functions; concavity; maximum and minimum values of a function, graphs of including rational functions; the indefinite integral; the fundamental theorem of calculus; the area between two curves; inverse functions; logarithmic and exponential functions; hyperbolic functions.

Al-Balqa Applied University Course Description 5005102 Computer Skills (2) (2-) Basics of programming, algorithm development using top-down design with syntax and semantics of the C++ programming language, Creating, compiling and executing C++ programs, Primitive data types, operations, control structures, procedures and functions, arrays and classes. Pre- requisite: 5005101 0206101 General Chemistry (1) (-0) Fundamentals of chemical changes, The periodic table and some properties of the elements, Stoichiometry, quantitative chemical relationships, Reactions between ions in aqueous solutions, Oxidation-reduction reactions, Atomic and electronic structure, Chemical Bonding, Chemical bonding and molecular structure. 0206102 General Chemistry Lab (1) 1(0-) Laboratory techniques, Chemical observations, Measurements of volume and mass, Limiting reactant in a salt mixture, Empirical formula for magnesium oxide, Standardization of sodium hydroxide solution, Vinegar analysis, metathesis reactions, Separation and identification of common ions. Determination of Na and K by flame photometer. 020610 General Chemistry (2) Co- requisite: 0206101 (-0) States of matter and intermolecular forces, Properties of solutions, Chemical thermodynamics, Chemical kinetics, Chemical equilibrium in gaseous systems, Electrochemistry, Acid-Base equilibrium, Solubility and complex ion equilibrium. 0206104 General Chemistry Lab (2) Pre- requisite: 0206101 1(0-) Molar mass of a volatile liquid and a solid from freezing point depression, Calorimetry, Thermo chemistry and Hess s law, Studies on some factors affecting chemical reaction, Le Chatelier s principle, Equilibrium constant of a chemical reaction using visible spectrophotometer. Oxidation-reduction reactions, Galvanic cells, Electrolytic cells, Faradays laws, Molar solubility and common ion effect. Co- requisite:020610 0404151 General Biology (1) (-0) Water (importance for environment and living organism), Macromolecules (structure and function). Structure and function of prokaryote and eukaryotes, cell division (mitosis meiosis). Molecular genetics and DNA technology, Genetics of virus and bacteria. respiration, photosynthesis, fungi, plants (structure, growth, reproduction and development). 0404152 General Biology (2) (-0) Metabolism and Enzyme, cell membrane (structure and function), Mendel and Gene idea, chromosomal bases of inheritance, origin of species, vertebrate and invertebrate, animal (structure, function, nutrition, reproduction, development, and nervous system), ecology of organisms. Pre- requisite: 040415 040415 General Biology Lab (1) 1 (0-) Microscope, cell of plants and animals, (structure and division), chemical and physical properties of cell, enzymes, photosynthesis, cell division (mitosis meiosis). plant tissues, plant organs (Stems, roots, leaves, flowers and fruits).

Co- requisite: 0404151

Al-Balqa Applied University Course Description 0404154 General Biology Lab. (2) 1 (0-) Diversity of organisms, kingdom of Bacteria, Fungi, Plant, protozoa, and Animals (development and tissue), genetics, molecule genetics, plant tissue culture, animal tissues, animal anatomy I & II. Co- requisite: 0404152 0402221 Microbiology (2-) Discovery of microorganisms - General features - Morphological and structural organization - microbial nutrition - Culture media - Growth curve - Measurement of microbial growth. Ultra structure of bacteria, fungi, algae, protozoa and viruses - Classification of microbes (molecular taxonomy) - Current methods of microbial identification - Plant microbe interactions - Human pathogens - Disinfectants and antibiotics - Environmental microbiology - Metabolism in prokaryotes. Pre-requisite: 0404152 0402 Plant Physiology (2-) Water and mineral absorption, Translocation and transpiration, photosynthesis, mineral nutrition, plant hormones and plant growth regulators, growth development, germination and dormancy, stress physiology, tension and pressure. Pre- requisite: 040211 04041 Plant (-0) Plant genome specialties- genetic engineering of plants, methodology- plant transformation with Ti plasmid of Agrobacterium tumifacians- Ti plasmid derived vector systems- physical methods of transferring genes to plants microprojectile bombardment, electroporation- use of reporter genes in transformed plant cellsmanipulation of gene expression in plants- production of marker free transgenic plants- application of plant genetic engineering- marker aided selection in plant breeding RFLP, RAPD and AFLP- ethics and issues regarding genetically modified plants. Pre-requisite: 0402 040412 Plant Tissue Culture (2-) Laboratory organization- sterile techniques- media composition- tissue and organ culture- establishment and maintenance of callus and suspension cultures- somatic embryogenesis- Control of organogenesis and embryogenesishaploid production - embryo culture and rescue in agricultural and horticultural corps- protoplast isolation, culture and regeneration of somatic hybrid- somatic embryogenesis and artificial seeds- mutants for salts, disease, cold, drought, herbicide and other stress conditions- plant micropropagation- meristem culture and virus elimination- shoot tip culture- cryopreservation and germplasm conservation- tissue culture applications. Pre-requisite: 04022 040421 General Genetics (2-) Madelian genetics, inheritance of chromosomes, multiple alleles, linkage and crossing over, genetic variation, principles of molecular genetics, principles of population genetics. Pre-requisite 0404154 040424 Biostatistics (-0) General statistical concepts, measurements of central tendency, measurements of variation, statistical graphs, Chi-square test, t-test, regression, complete randomized design, randomized complete block design. Pre-requisite: 0202101 04041 Cell Biology (-0) Biological macromolecules - prokaryotic and eukaryotic cells - cell cycle and cell division - detailed structure of the cell membranes - cellular organelles- transport across cell membrane receptors - signal transduction - cell differentiation. Pre-requisite: 0404154

Al-Balqa Applied University Course Description 04042 Molecular Biology (2-) Structure, function and analysis of proteins - structure and analysis of nucleic acids - gene cloninggenetic library - operon and gene regulation - the genetic code and protein synthesis - DNA replication - methods used in molecular biology research - DNA cloning methodologies- recombinant DNA clone selection and characterization- polymerase chain reaction, restriction mapping, DNA sequencing and hybridization- applications of recombinant DNA technology in medicine, industry, agriculture, aquaculture and environmental protection. DNA protein interaction- eukaryotic RNA polymerase and promoters- general transcription factors of eukaryotes- transcription activators and repressors of eukaryotes. Pre-requisite: 04041 04044 Animal Physiology (2-) Structure and function of the nervous system - cardiovascular and respiratory systems and their responses to drugs - organization and structure of the endocrine system and the functions of hormones - male and female reproductive physiology. Pre-requisite: 0404154 0404402 Seminar 1 (1,0) Self-study the objective of the course is to impart training to the student to collect literature from various sources on a given topic in the field of biotechnology. The student will learn to make written and oral presentations of the information obtained by self-study. The topics for this course will cover all aspects of biotechnology. 040440 Graduation Project (0-0) A theoretical and/or experimental investigation of a fundamental or practical problem in applied biology and biotechnology. 0404401 Field Training 6 (0-0) Training the students in research centers and laboratories that related to biotechnology in order to give them scientific and practical experience. 0404411 Food (-0) Principles of biochemical engineering- alcoholic beverages production- genetics and food biotechnologymicroorganisms-based processes and products- modern advances in food biotechnology- biosensors for biological monitoring- novel biotechnology and food safety. Pre-requisite: 020622 0404414 Animal (-0) Genetic Engineering in animals- transformation of animal cells- cloning vectors and expression vectorsanimal viral vectors and yeast vectors- vaccines and hormones- production of useful proteins in transgenic animals- AIDS- oncogenes and anti-oncogenes- phage display technology- signal transduction- baculoviruses in biocontrol and foreign gene expression- biotechnology of aquaculture- transgenic animals -in vitro fertilization and embryo transfer- use of nucleic acid probes and antibodies in clinical diagnosis and tissue typing- mapping of human genome- RFLP and applications- gene therapy- ethical issues in animal biotechnology. Pre-requisite: 04044 0404422 Microbial Genetics (-0) The evolution of microbial genetics- Early concept of bacterial variation- Adaptation, mutation and selection- Genetics of Bacteria- Genetics of fungi- Genetics of Viruses.

Pre-requisite: 0402221

Al-Balqa Applied University Course Description 040442 Molecular Genetics (-0) Identification of DNA as the genetic material- Gene as the unit of mutation and recombination- mutations (molecular nature)- recombination control (models and mechanisms) - gene as the unit of expression- co linearity of gene and polypeptide- elucidation of the genetic code- regulation of gene expression- promoter, operator, terminator and alternator - DNA damage and repair - extrachormosomal heredity- organization of chromosomes- chromosome abnormalities - quantitative inheritance and population genetics - developmental genetics using Drosophila as model system - somatic cell genetics. Pre-Requisite: 04042 04044 Genetic Engineering (2-) Gene cloning vectors - Isolation and manipulation of DNA - Characterization of DNA and RNA - Construction of DNA libraries - Preparation of DNA and RNA probes - Screening of DNA libraries for identification of desired clones - Polymerase chain reaction - Expression of cloned genes - Construction of transgenic organisms - Applications of genetic engineering - Recombinant DNA technology - cloning vectors- gene library - cloning of foreign genes - DNA delivery - genetic transformation of prokaryotes - marker genes- gene expression in prokaryotes - recombinant protein production in yeast - mammalian cell expression vectors - directed mutagenesis - transposon mutagenesis - sitespecific recombination Gene targeting. Pre-requisite: 04042 40444 Bioinformatics (-0) This course provides an introduction to bioinformatics with a focus on fundamental bioinformatics problems, the tools used to compute solutions to those problems: Bioinformatic databases, pairwise sequence alignment, multiple sequence alignment, gene prediction, gene expression data analysis, phylogenetics, RNA structure prediction, protein structure prediction, comparative genomics, proteomics Pre-requisite: 04042 0404441 Immunology (-0) Cells and tissues of immune system- types of immunity: innate, acquired, passive and active- antibody structure and function- antibody diversity- major histo compatibility complex- antigen processing and presentation to T cells - antigen recognition and activation of immune response- regulation of immune response- autoimmunity- hyper sensitive reactions- complement system- techniques exploiting antigen antibody reactions- generation of monoclonal and polyclonal antibodies- immunoassays and their relevance to modern living Pre-requisite: 020622, 0402221 0404442 Virology (2-) History - nomenclature system - replication strategies - the major families of viruses infected animals, humans, and plants transmission - isolation and purification - physical properties serology - control measures. Pre-requisite: 020622 0404444 Microbial (-0) Microbial production of therapeutic agents- vaccines- synthesis of commercial products by recombinant microorganisms- microbial degradation of xenobiotics- production of single cell protein from carbohydratesfermentation - microbial food products- production of industrially important chemicals- biomass utilization of food, fuels and chemicals- role of microbes in dairy products, flavors- protein secretion in bacteriabiological insect control- pollution and waste control- environmental release and monitoring of genetically modified/engineered organisms.

Pre-requisite: 0402221

Al-Balqa Applied University Course Description 040121 Principle of Environmental Science (-0) Introduction to environmental science; ecosystem, nutrient cycle, pollution, impact. Environmental pollution; water, soil, air, and noise. Sustainable development. 040251 Principles of Plant Protection (-0) The importance and history of plant protection with emphasis on the role of plant protection in worldwide food security. To study the basics of Entomology, Plant Pathology, Apiculture and Weed Science.To study the different methods of pest control and the ecological basis of pest management. Pre-requisite: 0404152 04071 Principles of Agricultural Extension (-0) The concepts about agricultural extension, importance, philosophy, principle, objectives and the role integrated rural development, in addition to rural leadership and its important in agricultural extension, communication process and its role in adoption the agricultural innovation, planning, implementation and evaluation extensional programs by using extension methods and means and giving an idea about actual extensional work in Jordan 040415 Environmental (-0) This course discusses the principles and commercial applications of biotechnology to environmental problems. The course is structured to promote self-learning and students' development of Biotech solutions to real-life problems. Individual subject areas include the use of biotechnology to clean up or 'bioremediate' polluted environments as well as the economic recovery of important minerals and precious metals through 'phytomining'. Furthermore, the application of biological systems in preventing pollution by supporting our planet's sustainable development is also explored in subject areas such as 'biofuels' and 'bioplastics' Pre-requisite: 0402221 040445 Biosafety (-0) Describe current and future issues and concerns associated with biological hazards and its control in diagnostic, treatment, research facilities and decontamination. Describe the statistical and technical problems involved with microbial sampling and current methods for detecting, counting, and identifying microbes in the environment. Discuss the relevant policies, guidelines, and standards that apply to work involving potential exposures to infections microorganisms. Pre-requisite: 04042 0404445 Special Topics (-0) Any subject that is not included in the curriculum will be submitted under this course if required by the students. Pre-requisite: 04041 040211 Principles of Plant Production (-0) Principles of growth and development of cultivated species.methods of propagation. Environmental factors affecting crop production. Culture and use of fruit, vegetable, flower, ornamental, forest and agronomic crops. Pre-requisite: 0404152 0206221 Organic Chemistry (2-) Introduction to organic chemistry. Nomenclature, structure, physical properties, reactions and synthesis of major organic functional groups. Intended for health science majors. Topics include structure and reactions of alkanes, alkenes, alkynes, alkyl halides, and aromatic molecules; nomenclature of organic compounds; stereochemistry; reaction mechanisms and dynamics

Prerequisite:020610

Al-Balqa Applied University Course Description 0206241 Analytical Chemistry (2-) survey of the methods of inorganic quantitative analysis, including the methods of gravimetric and volumetric analysis with the use of simple instrumental methods included. Laboratory experiences involving the qualitative and quantitative analysis of chemical compounds including gravimetric, volumetric and spectrophotometric methods. Prerequisite: 020610 020622 Biochemistry (2-) An introduction to the chemistry of life processes, the composition of living matter and the changes associated with biological processes. A laboratory course in which the properties of biochemical molecules are explored and common biochemical reactions are examined. Prerequisite:0206221