PHD DAY 2016 PROGRAMME LOCATION: THE LAKESIDE LECTURE THEATRES 22 JANUARY 2016

PROGRAMME & ABSTRACTS 22 JANUARY 2016

PHD DAY 2016 PROGRAMME LOCATION: THE LAKESIDE LECTURE THEATRES 22 JANUARY 2016 8.30 Welcome Professor Lise Wogensen Bach, Vice-Dean and Chair of Graduate School, Health, AU 8.40 Welcome and today s program PhD student Johan Frederik Håkonsen Arendt, Chairman of the PhD Association, Health, AU 8.45 Fogh-Nielsen Competition Chaired by Professor Søren K Moestrup, Chairman of the Fogh-Nielsen board 9.30 Coffee/tea and fruit break 9.45 Oral presentations The Lakeside Lecture Theatres and the Bartholin Building (build. 1241) 11.15 Break 11.30 Poster presentations The lakeside Lecture Theatres, the Bartholin Building (build. 1241), and Anatomy (build. 1230) 12.45 Lunch /poster viewing The lakeside Lecture Theatres, the Bartholin Building (build. 1241), and Anatomy (build. 1230) 13.55 Set Science Free, keynote lecture Rupert Sheldrake, Author and Biologist, Fellow of Schumacher College, Devon, UK Introduced by Professor Lise Wogensen Bach 14.45 Coffee/tea and cake break 15.00 Set Science Free, panel discussion Discussion moderator: Professor Ole Steen Nielsen, Vice-Dean, Health, AU Panel participants: PhD Student Peter Sinkjær Kenney, AU Professor Charlotte Ringsted, Vice-Dean, AU Professor Gorm Greisen, KU Professor Jens Christian Djurhuus, AU 16.30 Awards, Posters and oral presentations Professor, Ebba Nexø and PhD Student, Christoffer Tobias Witt, Chair and Co-chair of the Organizing Committee, PhD day 2016 16.45 Closing remarks Professor Lise Wogensen Bach 18.30 Dinner and awards ceremony for the JCD and the Fogh-Nielsen Competition Centralværkstedet Festive speech by Professor Lars Østergaard

Aarhus University Graduate School of Health PHD DAY 22 JANUARY 2016 1

Practical Information Posters should be hung up between 16:30 and 19:00 on 21 January or between 7:30 and 8:00 on 22 January. All posters must be taken down before 15:00 Oral presenters for sessions O1-O5 must meet in the auditorium concerned between 7:30 and 8:00 on 22 January to save their presentation onto the auditorium hard disk. Lunch is served at the Lakeside Lecture Theatre and at the poster viewing areas in the Bartholin Building and at Anatomy. Oral session 1: Lakeside Lecture Theatres, Per Kirby Auditorium Oral session 2: Lakeside Lecture Theatres, Merethe Barker Auditorium Oral session 3: Lakeside Lecture Theatres, Eduard Biermann Auditorium Oral session 4: Lakeside Lecture Theatres, Jeppe Vontilius Auditorium Oral session 5: Bartholin building, Auditorium 1 Poster session 1-6: Lakeside Lecture Theatres, William Scharff Auditorium Poster session 7-22: Bartholin building, Auditorium 2, 3, 4, Studyroom, Gardenroom, room 130 and halls. Poster session 23-30: Anatomy (building 1230): Hall and Colloquium room 1 Organizing committee: Ebba Nexø, Professor, Department of Clinical Medicine, Chairman Christoffer Tobias Witt, PhD student, Department of Clinical Medicine, Co-chairman Alexander Juhl Andersen, PhD student, Department of Clinical Medicine Anne Louise Hansen, PhD student, Department of Biomedicine Bo Hønge, PhD student, Department of Clinical Medicine Helle Mellerup, PhD Administration Jakob Appel Østergaard, Postdoc, Department of Clinical Medicine Kasper Pryds, PhD student, Department of Clinical Medicine Katrine Lehmann, PhD Administration Kirstine Kirkegaard, Postdoc, Department of Clinical Medicine Line Petersen, PhD student, Department of Clinical Medicine Maryam Ardalan, PhD student, Department of Clinical Medicine Nanna Sophie Brinck-Jensen, PhD student, Department of Clinical Medicine Nichlas Riise Jespersen, PhD student, Department of Clinical Medicine Peter Skov Jensen, PhD student, Department of Clinical Medicine Rasmus Pihl, PhD student, Department of Biomedicine Rikke Nørregaard, Associate Professor, Department of Clinical Medicine Trine Wigh Arildskov, PhD student, Department of Clinical Medicine Social media: Facebook: PhD Association Health Twitter: #auphd16

E. Biermann Oral 3 Merethe Barker Oral 2 Level 2 Foyer J. Vontillius Oral 4 William Scharff Poster session 1-6 Level 3 Per Kirkeby Main Venue Oral 1 Level 4 Bartholin Building Oral 5 Poster session 7-22 Anatomy Poster session 23-30

Set Science Free On behalf of the PhD Association, the Graduate School of Health, Aarhus University and this year s Organizing Committee, we welcome all students, faculty members and distinguished guests to the PhD Day 2016. You are invited to enjoy five oral and 30 poster sessions as well as the Fogh Nielsen Competition. Furthermore, this year s topic aims to inspire your to answer the question What can I do to set science free. Our Keynote Speaker, the inspiring biologist and author of best-selling books, Rupert Sheldrake will provoke our current paradigm for scientific thinking. The panel discussion will question issues related to entrepreneurship, education, ethics and the research environment, based on presentations by PhD Student Peter Sinkjær Kenney, AU, Professor Charlotte Ringsted, Vice-Dean, AU, Professor Gorm Greisen, KU and Professor Jens Christian Djurhuus, AU. By the end of the day we hope that every one of you will be full of ideas as how to set science free. A warm thank you goes to everybody who has taken their time to participate and help to make the PhD day of 2016 a joyful and inspiring event. Professor Ebba Nexø Chairman of the Organizing Committee Health, Aarhus University Vice-dean Lise Wogensen Bach Head of Graduate School Health, Aarhus University Professor Allan Flyvbjerg Dean Health, Aarhus University PhD student Christoffer Tobias Witt Co-Chairman of the Organizing Committee Health, Aarhus University

The Keynote Lecture Rupert Sheldrake, Biologist Dr Sheldrake is the author of more than 80 scientific papers and 11 books. He was educated at Cambridge and Harvard Universities, and has a PhD from Cambridge in biochemistry. He was a Fellow of Clare College, Cambridge, a Research Fellow of the Royal Society, Principal Plant Physiologist at ICRISAT (the International Crops Research Institute for the Semi-Arid Tropics) in Hyderabad, India, and from 2005-2010 the Director of the Perrott-Warrick Project, funded from Trinity College, Cambridge. He is a Fellow of the Institute of Noetic Sciences, in California, a Fellow of Schumacher College, Dartington, England, and a visiting professor at the Graduate Institute in Connecticut. In his book Science Set Free (2012; published in the UK as The Science Delusion), Sheldrake shows that science is being constricted by assumptions that have hardened into dogmas. The 'scientific worldview' has become a belief system, which claims that everything is material or physical, nature is purposeless, and is governed by changeless laws of nature that suddenly appeared at the moment of the Big Bang. Consciousness is nothing but the physical activity of brains, and is imprisoned within our skulls. Sheldrake examines these dogmas scientifically, and shows that science would be better off without them: freer, more interesting, and more fun. In 2013 the Duttweiler Institute in Switzerland placed him among the top 100 Global Thought Leaders. In 2014 he received the Doshi Bridgebuilder Award at Loyola University, Los Angeles, and in 2015 he was awarded the Lucia Cianci Prize for innovative thinking in Venice. He lives in London with his wife Jill Purce, and they have two sons. His web site is www.sheldrake.org.

PHD ASSOCIATION HEALTH The PhD association for all PhD students at the Faculty of Health, Aarhus University ORGANISATION GRADUATE PROGRAM FORUM PHD COMMITTEE GENERAL ASSEMBLY (open to all PhD students at Health) THE ACADEMIC COUNCIL PHD COURSE EVALUATION 19 BOARD MEMBERS (and an unlimited number of active members) THE ORGANIZING COMMITTEE OF THE PHD DAY AFTER-WORK MEETINGS TOGETHER WITH THE PHD HOUSE AARHUS UNIVERSITY PHD ASSOCIATION We aim to create better education and better conditions for PhD students at the Graduate School of Health. Join us on Facebook at: PhD Association Health or check out our webpage: phdassociation.dk ALL PHD STUDENTS CAN JOIN!

Working hard for you! phdassociation.dk

AU LIBRARY HEALTH SCIENCES THE LIBRARY IS HERE TO HELP Information about: - Tips and tricks for PubMed, Embase, Scopus, and Cinahl - Citation searches in Scopus and Web of Science - Alerts from your favourite journals - Reference Tools courses and support for EndNote and RefWorks - Bibliometrics and Research Evaluation; e.g. Bibliometric Research Indicator (BFI), Journal Impact Factor, ORCID and H-index - Copyright and Open Access Support and help for literature search designed for your specific project Regular PhD courses Literature Search in Medical Databases AARHUS AU UNIVERSITET AU Library, Health Sciences Victor Albeck Building Vennelyst Boulevard 4 DK-8000 Aarhus C Tel. +45 8946 2362 sundhedsvidenskab@statsbiblioteket.dk Opening Hours Monday Thursday 9 a.m. - 5 p.m. Friday 9 a.m. - 3 p.m. library.au.dk

Student counsellor for PhD students Surviving you dissertation From time to time it is more than a book title. In the knowledge that studying for a PhD can be an overwhelming challenge, then Health has established a student counsellor for PhD students. What would you answer if I asked: Is it difficult to plan your daily work? Are things not working? Is it hard to collaborate with your supervisor? Do you find your situation as a PhD student difficult or unsatisfactory? I am always an interested listener. As PhD student counsellor I am a professional interlocutor. Conversations with me are confidential and anonymity is promised. It is not an alternative to the professional research supervision. By means of conversations, the counsellor can help students become aware of what they perceive as difficult and why. This is done in close collaboration with the Secretary of The Graduate School of Health if the process related issues have administrative elements. The intention is to help PhD students gain clarity, come to terms with their situation. It is also to help them to see other opportunities, if they experience personal problems or other difficulties related to the process of working and studying as a PhD student. The counsellor can also assist students to make competent decisions. You are always welcome to contact the PhD student counsellor! Sometimes sooner is better than later - no problem is too small for a talk. Personal contact: Sanne Angel phdstudievejleder@sun.au.dk Phone: 871 67889

IT S YOUR TALENT IT S YOUR CAREER IT S YOUR CHOICE Do you know which career path to choose when finishing your PhD? AU CAR E E R PH D S E RV ICES Do you know which specific competences companies are interested in regarding PhD students from Health? Competency mapping Are you aware of your many opportunities? Information on career opportunities AU CAREER PHD Individual feedback on career paths, applications and CVs A mentor from the industry Career Talks with a PhD alumni Career events Vibeke Broe PhD Career Consultant Mobile: 2942 6029 Email: vibr@au.dk AU AARHUS UNIVERSITY AU Career PhD website: phd.au.dk/career https://www.facebook.com/aucareerphd/

International Academic Staff Services (IAS) at the International Centre In close collaboration with AU Human Resources, International Academic Staff Services (IAS) helps foreign researchers (incl. PhD students) and their families through the practical challenges tied to living in Denmark. As part of this, the unit operates a help desk and a website www.ias.au.dk. IAS provides counsel for international PhD students and their family about issues of relevance, incl. job for the spouse, international schools and nurseries. The unit also provides information about practicalities for PhD students planning a research stay abroad. Furthermore, IAS assists international staff and PhD students with the paperwork and practical challenges during their stay in Denmark, e.g. health insurance and extension of residence and work permits. The IAS help desk is open Monday, Wednesday & Friday 10am-2pm and Thursday 10am-1pm at the International Centre. To make the transition to Denmark as easy as possible, IAS encourages new internationals to participate in the AU introductory events. The AU Introduction Day gives a general introduction to AU as an organisation and takes place every other month. Additionally, twice a month IAS organises Getting Started in Denmark which provides important on-arrival orientation and registration for newly arrived international PhD students and researchers. www.ias.au.dk/gettingstarted Lastly, IAS helps to arrange social and cultural activities for staff and their families through the University International Club (UIC). www.au.dk/uic PhD House Activity Group The PhD House Activity Group is an interdisciplinary group of volunteer PhDs and postdocs that organises a wide range of social and academic events primarily aimed at both Danish and international PhDs and post docs. The group is working to enhance the junior researchers environment at Aarhus University and is always looking for new enthusiastic members. The PhD House The PhD House is located in the Dale T. Mortensen Building (International Centre). The PhD House offers a combination of administrative services, lecture rooms for PhD courses on transversal skills and Dale s Café offering quality coffee, sandwiches and a wide selection of beers. Furthermore, the PhD associations have the possibility to use the facilities in the PhD House for events. IC Dormitory for international PhD students is also part of the Dale T. Mortensen Building. The PhD House is, thus, a focal point for national and international PhD students to meet both professionally and socially. www.phd.au.dk/phdhouse The International Centre AU International Centre is located in the Dale T. Mortensen Building (Høegh- Guldbergs Gade 4). Among others, it contains IAS and the housing department, which deals with housing matters for international students and staff.

Do you need funding for your research? The Health Team at The Research Support Office can help you tailor a competitive application and make a realistic budget. Our database www.researchfunding.net will help you find funding opportunities. Research Support Office Proposal Development Aarhus University & Aarhus University Hospital www.au.dk/fse

Danish Diabetes Academy Are you interested in diabetes research? Then the Danish Diabetes Academy could be something for you. In 2016, the Academy is offering three major residential PhD courses: Basal Metabolism and Molecular Mechanism in the Metabolic Syndrome Diabetes and Epidemiology Summer School in Diabetes and Metabolism. The Academy is also organizing a number of scientific seminars and workshops on diabetes and metabolism in 2016, where national and international experts will give lectures at the highest level. The Academy is a national network platform for both clinical and basic researchers and anyone with an interest in diabetes research can become a member of the Academy. Currently, there are almost 700 members. The Academy's overall vision is to ensure high quality in diabetes research and diabetes care in Denmark for the benefit of present and future diabetes patients. Further information about the Academy's PhD courses, seminars, workshops and travel grants is available on the Academy's website www.danishdiabetesacademy.dk or on Facebook and LinkedIn. Best regards Tore Christiansen Managing Director Danish Diabetes Academy "The academy is funded by the Novo Nordisk Foundation and co-funded by the universities in Denmark"

Dear PhD student We hope that you are enjoying the PhD Day and taking the opportunity to network, have fun, learn, and discuss mutual interests. In AUPA, we believe that such activities are an important part of the PhD study. We also realize the necessity of support along the way. Therefore, we discuss and confront general matters like financing, work/life balance, loneliness, teaching loads, and other topics that might be of interest to you. We represent all faculties, and PhD Association Health currently has two seats. We also keep you and your local association updated on events, news in university politics, discussions and initiatives. You can find us on Facebook: AUPA or via www.phd.au.dk/aupa You can also find us through the PhD Association Health. Or join our next General Assembly on March 10th at 2 pm in Dale s building, meeting room 2. Love, AUPA AU PA AUPA Aarhus University PhD Association

We welcome all our PhD students to the PhD Day 2016 www.colourbox.dk

Session Chairmen Fogh Nielsen Competition Søren Kragh Moestrup (chairman) & Kasper Pryds (PhD student) O1 O2 O3 O4 O5 Bo Løfgren & Simon Fristed Eskildsen Ulf Simonsen & Mads F. Kjølby Poul Henning Jensen & Mette Richner Jens Leipziger & Per Bendix Jeppesen Hans Jürgen Hoffmann & Mette Nørgaard P1 P2 P3 P4 P5 P6 P7 P8 P9 P10 P11 P12 Henrik Schrøder, Anil Anil (PhD student), Jeong Shim (PhD student) & Peter Parbo (PhD student) Holger Jon Møller, Mariann Tang (PhD student), Krystian Figlewski (PhD student) & Jesper Løkke Mehlsen (PhD student) Kirstine Kirkegaard, Thorbjørn Søndergaard Engedal (PhD student), Birgitte Sandfeld Paulsen (PhD student) & Polina Martinkevich (PhD student) Uffe Birk Jensen, Sven Robert Andresen (PhD student), Heidi Buvarp Dyrop (PhD student) & Linda Christie Andrea (PhD student) Helle Prætorius, Anne Wandler (PhD student), Nikolaj Raaber (PhD student) & Marianne von Euler Chelpin (PhD student) Christian Fynbo Christiansen, Jörg Schullehner (PhD student), Lars Høj Markvardsen (PhD student) & Kristian Ravlo (PhD student) Arne Møller, Line Petersen (PhD student), Trine Majken Gade Bonnesen (PhD student) & Mikkel Petersen (PhD student) Holger Brüggemann, Xianwei Zhang (PhD student), Christian F.P. Scholz (PhD student) & Omar Majed Abuyaman (PhD student) Jeppe Prætorius, Lilliana Beck (PhD student), Stig Hill Christiansen (PhD student) & Kasper Fjellhaugen Hjuler (PhD student) Mette Madsen, Michael Aagaard Andersen (PhD student), Trine Maxel Juul (PhD student) & Maria do Nascimento Lopes Primo (PhD student) Anne Landau, Maiken Ina Siegismund Kjærsgaard (PhD student), Peter Breining (PhD student) & Susanne Friis Søndergård (PhD student) Yuelian Sun, Kirstine Høj Obling (PhD student), Erhard Næss-Schmidt (PhD student) & Susanne Hvolgaard Mikkelsen (PhD student) 17

P13 P14 P15 P16 P17 P18 P19 P20 P21 P22 P23 P24 P25 P26 P27 P28 P29 P30 Karl-Anton Dorph-Petersen, Liv Solvår Nymark (PhD student), Yuduo Zheng (PhD student) & Sara Marie Hebsgaard Offersen (PhD student) Søren Dinesen Østergaard, Louise Kærholm Schæbel (PhD student) & Anneli Clea Skjelmose Bolund (PhD student) Peter Bross, Ida Skødt Jensen (PhD student), Peter Skov Jensen (PhD student) & Lea Ladegaard Grønkjær (PhD student) Jakob Blicher, Peter Agger (PhD student) & Lise Maria Lindahl (PhD student) Jens Christian Djurhuus, Torbjørn Brøgger (PhD student) & Rune Wilkens (PhD student) Lise Lotte Hansen, Kristina Margareta Öbrink-Hansen (PhD student) & Laura Ozer Kettner (PhD student) Michael Mulvany, Mark Klitgaard Nøhr (PhD student) & Jeppe Bakkestrøm Rosenbæk (PhD student) Michael R. Horsman, Mette Bohl Larsen (PhD student) & Esben Ahlburg Eickhardt (PhD student) Michael Winterdahl, Sakthidasan Jayaprakash (PhD student), Le Le (PhD student) & Iben Lyster Daugaard (PhD student) Niels Gregersen, Simple Futarmal Kothari (PhD student) & Susanne Rylander (PhD student) Per Höllsberg, Jennie Maria Christin Strid (PhD student) & Line Brøndum (PhD student) Reimar W. Thomsen, Bjørn Borsøe Christensen (PhD student), Anne Mette Falstie-Jensen (PhD student) & Maria Ervandian (PhD student) Rikke Katrine Jentoft Olsen, Janni Lisander Larsen (PhD student), Sandra Kruchov Thygesen (PhD student) & Pernille Skjold Kingo (PhD student) Tove Christensen, Rebeka Bodak (PhD student) & Hang Nguyen Nielsen (PhD student) Ulla Breth Knudsen, Mette Thorgaard (PhD student) & Eva Natalia Glassou (PhD student) Venerino Poletti, Luise Borch (PhD student), Mads Skipper (PhD student) & Mai Lykkegaard Schmidt (PhD student) Vladimir Matchkov, Mia Møller (PhD student) & Desiree Leduc (PhD student) Vivien Schack, Lone Vedel Schøler (PhD student), Henriette Lajgaard Christensen (PhD student) & Anders Patrik Alexander Gunnarsson (PhD student) 18

Session Overview Fogh Nielsen Oral session 1 Stinne Ravn Greisen. THE WALKING DEAD - PD-1 EXOSOMES Kaja Zuwala. MACROMOLECULAR PRODRUGS OF PANOBINOSTAT IN HIV- ANTILATENCY TREATMENT Lars Andersen. THIAMINE AS AN ADJUNCTIVE THERAPY IN CARDIAC SURGERY: A PHASE II, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL Chairmen: Bo Løfgren & Simon Fristed Eskildsen O01.01 Lene Odgaard Hellmund. RETURN TO WORK AFTER SEVERE TRAUMATIC BRAIN INJURY IS LOW: A NATIONWIDE FOLLOW-UP STUDY O01.02 Maria Theresa Wimberley Böttger. INVERSE ASSOCIATION BETWEEN URBANICITY AND TREATMENT RESISTANCE IN SCHIZOPHRENIA O01.03 Nils Henrik Stubkjær Hansson. MYOCARDIAL EXTERNAL EFFICIENCY IN PATIENTS WITH INCREASING SEVERITY OF AORTIC VALVE STENOSIS - A BIPHASIC RESPONSE DUE TO THE UTILIZATION AND EXHAUSTION OF NORMAL MYOCARDIAL RESERVES O01.04 Anders Møllekær. EMERGENCY DEPARTMENT PATIENT CHARACTERISTICS LENGTH OF STAY AND 72-HOUR READMISSION O01.05 Sofie Hertz Rønn. VITAMIN K2 TREATMENT PREVENTS POSTMENOPAUSAL MICROARCHITECTURAL DETERIORATION OF TRABECULAR BONE O01.06 Rasmus Cleemann. EFFECTS OF RECOMBINANT BONE MORPHOGENIC PROTEIN 2 ON IMPLANT INTEGRATION ON A BISPHOSPHONATE BACKGROUND - A DOSE RESPONSE STUDY WITH AND WITHOUT BONE ALLOGRAFT Oral session 2 Chairmen: Ulf Simonsen & Mads F. Kjølby O02.01 Mette Damborg Hansen. SUBSTITUTIONS OF VEGETABLES AND POTATOES AND RISK OF MYOCARDIAL INFARCTION O02.02 Nikolai Hoffmann-Petersen. HIGH PREVALENCE OF HYPERTENSION IN A DANISH POPULATION - TELEMEDICAL HOME MEASUREMENT OF BLOOD PRESSURE IN CITIZENS AGED 55-64 YEARS IN HOLSTEBRO COUNTY O02.03 Gro Egholm. DUAL ANTI-PLATELET THERAPY AFTER CORONARY DRUG-ELUTING STENT IMPLANTATION AND SURGERY-ASSOCIATED MAJOR ADVERSE EVENTS O02.04 Susanne Bendesgaard Pedersen. REGIONAL VARIATION IN USE OF IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS (ICDS) IN DENMARK O02.05 Niels Secher. THE IMPACT OF AGE ON CORONARY PERFUSION, CARDIAC FUNCTION AND INFLAMMATION IN A RAT MODEL OF ASHPYXIAL CARDIAC ARREST 19

O02.06 Peter Rubak. MONITORING LOW-DOSE ASPIRIN THERAPY USING ULTRA HIGH PERFORMANCE LIQUID CHROMATOGRAPHY Oral session 3 Chairmen: Poul Henning Jensen & Mette Richner O03.01 Hans Christian Brix Nørgaard. INCREASED USE OF PRIMARY CARE DURING SIX YEARS OF PRODROMAL SCHIZOPHRENIA O03.02 Sofie Christiansen. THE CLOCKWORK BEHIND DEPRESSION - CIRCADIAN DISTURBANCES IN A RAT CHRONIC MILD STRESS MODEL OF DEPRESSION O03.03 Ali H. Rafati. APPLICATION OF NEWLY DEVELOPED STEREOLOGICAL TOOLS FOR QUANTIFICATION OF NEURONAL SIZE, SHAPE AND DIRECTION AS WELL AS NEURONAL COLUMNARITY O03.04 Signe Væth. CHARCOT-MARIE-TOOTHS DISEASE: THE DEVELOPMENT OF A DIAGNOSTIC PLATFORM USING NEXT GENERATION SEQUENCING O03.05 David R.M.A. Højgaard. OBSESSIVE-COMPULSIVE DISORDER WITH TIC SYMPTOMS: CLINICAL PRESENTATION, FUNCTIONING AND COGNITIVE BEHAVIORAL THERAPY OUTCOME IN A SCANDINAVIAN SAMPLE OF CHILDREN AND ADOLESCENTS O03.06 Michael Væggemose. MAGNETIC RESONANCE DIFFUSION TENSOR IMAGING FOR EVALUATION OF DIABETIC POLYNEUROPATHY Oral session 4 Chairmen: Jens Leipziger & Per Bendix Jeppesen O04.01 Ane Bundsbæk Iversen. ASSESSMENT OF [ 11 C]-METFORMIN PET FOR IDENTIFICATION OF PATIENTS SUITABLE FOR METFORMIN TREATMENT O04.02 Ali Khalidan Vibholm. IN-VIVO IMAGING OF ACTIVATED NMDA RECEPTOR ION CHANNELS WITH THE NOVEL RADIOLIGAND 18 F-GE179 O04.03 Simon Gabriel Comerma Steffensen. CALCIUM ACTIVATED POTASSIUM CHANNELS IN ERECTILE FUNCTION: FOCUS ON POTASSIUM SMALL CONDUCTANCE CHANNELS O04.04 Rasha Abdelkadhem Al-Saaidi. MITOCHONDRIAL SPARE RESPIRATORY CAPACITY IS REVERSELY ASSOCIATED WITH IPSC REPROGRAMMING EFFICIENCY O04.05 Aida Solhøj Hansen. MODULATION OF CD46 ISOFORM EXPRESSION UPON ACTIVATION OF CD4+ T CELLS O04.06 Nina Jensen. A MOUSE MODEL FOR CEREBROVASCULAR CALCIFICATION 20

Oral session 5 Chairmen: Hans Jürgen Hoffmann & Mette Nørgaard O05.01 Alexander Fjældstad. FINGERPRINTING THE STRUCTURAL CONNECTIVITY OF OLFACTION O05.02 Peter Sinkjær Kenney. NASAL FILTERS ARE EFFICACIOUS IN PREVENTING ALLERGY SYMPTOMS: RESULTS FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CROSSOVER CLINICAL TRIAL O05.03 Gitte Juel Holst. INDOOR DAMPNESS - ASSOCIATIONS WITH ALLERGY AND RESPIRATORY HEALTH IN DANISH PUPILS O05.04 Troels Johansen. A METHOD FOR MAPPING REGIONAL OXYGEN AND CO 2 TRANSFER IN THE LUNG O05.05 Camilla Askov Mousing. PALLIATIVE CARE FOR PEOPLE WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IS A NEGLECTED AREA IN PRIMARY HEALTHCARE O05.06 Morten Thingemann Bøtker. BREATHING DIFFICULTIES ENTAILS HIGH MORTALITY IN 1-1-2 CALLERS - A POPULATION-BASED FOLLOW-UP STUDY Poster session 1 Chairmen: Henrik Schrøder, Anil Anil (PhD student), Jeong Shim (PhD student) & Peter Parbo (PhD student) P01.01 Rosa Andersen Mencagli. FUNCTION, STRUCTURE AND QUALITY OF STRIATED MUSCLES IN PATIENTS WITH MYOPATHY - AN MRI STUDY ON PATIENTS WITH POMPE DISEASE AND MYOTONIC DYSTROPHY P01.02 Cecilie Siggaard. MACROPHAGE ACTIVATION ASSESSED BY SOLUBLE CD163 AND SOLUBLE MANNOSE RECEPTOR IS ASSOCIATED WITH LIVER INJURY IN PATIENTS WITH ACETAMINOPHEN OVERDOSE P01.03 Vibe Morgana Poulsen. GENETIC FACTORS' IMPACT IN OVARIAN AGING: A RETROSPECTIVE STUDY P01.04 Marie Hauerslev CARDIOPROTECTIVE EFFECTS OF CHRONIC NITRATE TREATMENT: INFLUENCE ON THE EFFECT OF REMOTE ISCHEMIC PRECONDITIONING? P01.05 Gabriela Grove. PREDICTION MODEL FOR ASSESSMENT OF POST-OPERATIVE OUTCOMES FOR PATIENTS WITH PERIPHERAL ARTERIAL DISEASE P01.06 Emilie Sandgaard Pedersen. THE COMPLEMENT SYSTEM FOLLOWING CEREBRAL HAEMORRHAGE P01.07 Mai Eldon. BASAL CELL CARCINOMA: CLINICAL FOLLOW-UP VS. SMARTPHONE APP FOLLOW-UP P01.08 Andreas Hattesen. IS THE ABSORPTION OF ASPIRIN REDUCED AFTER CORONARY BYPASS GRAFTING? P01.09 Aske Hess Rosenquist. BEHAVIORAL DEVELOPMENT FOLLOWING EARLY LIFE ORGANOCHLORIDE EXPOSURE 21

P01.10 Emil Holck. EARLY HEALING AFTER NOVOLIMUS ELUTING BIORESORBABLE STENT IMPLANTATION IN TREATMENT OF CORONARY BIFURCATION LESIONS - THE BIFSORB PILOT STUDY Poster session 2 Chairmen: Holger Jon Møller, Mariann Tang (PhD student), Krystian Figlewski (PhD student) & Jesper Løkke Mehlsen (PhD student) P02.01 Malalai Musleh. SCD163 AND SCD19 AS POTENTIAL BIOMARKERS IN CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY (CIDP) - A STUDY OF SCD163 AND SCD19 IN THE CEREBROSPINAL FLUID P02.02 Lars Hansen. DYNAMIC RADIOSTEREOMETRIC ANALYSIS FOR EVALUATION OF FEMOROACETABULAR IMPINGEMENT AND POSTOPERATIVE RESULTS - A VALIDATION STUDY P02.03 Kathrine Stokholm. PRECLINICAL EVALUATION OF GRAFTING OF DOPAMINERGIC NEURONS DERIVED FROM HUMAN EMBRYONIC STEM CELLS FOR A FIRST IN HUMAN CLINICAL TRIAL IN PARKINSON'S DISEASE P02.04 Clara Medici. CAN ANTI-INFLAMMATORY DRUGS LOWER THE RISK OF ANXIETY AND DEPRESSION AFTER CRITICAL ILLNESS? P02.05 Jan Hansen. CARDIOPROTECTIVE MECHANISMS OF KV7 (KCNQ) CHANNEL INHIBITION P02.06 Anne Lind Malte. CARDIOVASCULAR BIOMARKERS IN PREECLAMPSIA AT TRIAGE P02.07 Kristina Aagaard. HEAD CIRCUMFERENCE AT BIRTH AND CHILDHOOD DEVELOPMENTAL DISORDERS: A NATIONWIDE COHORT STUDY P02.08 Claus Kjær Pedersen. ACCELERATED RULE OUT OF MYOCARDIAL INFARCTION - THE AROMI TRIAL P02.09 Johannes Bech. THE PORCINE CORTICOSPINAL SYSTEM: VERIFIED BY CONVENTIONAL NEURONAL TRACING AND MRI-FIBERTRACKING P02.10 Lene Andreasen. RANDOMIZED COMPARISON OF SIROLIMUS ELUTING OR BIOLIMUS ELUTING BIORESORBABLE POLYMER STENTS EVALUATED BY OPTICAL COHERENCE TOMOGRAPHY AFTER 13 MONTHS. THE SORT-OUT VII OCT STUDY Poster session 3 Chairmen: Kirstine Kirkegaard, Thorbjørn Søndergaard Engedal (PhD student), Birgitte Sandfeld Paulsen (PhD student) & Polina Martinkevich (PhD student) P03.01 Karen Sloth Madsen. THE CORRELATION BETWEEN ULCERATION-INDUCED INFLAMMATION AND A MIGRATORY PHENOTYPE IN METASTATIC MELANOMA P03.02 Rikke Elmose Mols. CORONARY COMPUTED TOMOGRAPHIC ANGIOGRAPHY AND DOWNSTREAM IMPACT IN GENERAL PRACTICE P03.03 Jonas Agerholm. FUNCTIONS OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2 (IGFBP-2) IN CANCER AND HEALTH 22

P03.04 Julia Helena Vonasek. LATE MORTALITY AND MORBIDITY AMONG LONG-TERM LEUKEMIA SURVIVORS WITH DOWN SYNDROME P03.05 Søren Skaarup. COMPARISON OF THREE ULTRASONIC METHODS TO ASSESS THE DIAPHRAGM MOVEMENT P03.06 René Tidemand Larsen. HEAD CIRCUMFERENCE AT BIRTH AND SCHOOL PERFORMANCE: A NATIONWIDE COHORT STUDY P03.07 Signe Hansen. ELECTROSPUN BIOMIMETIC NANOFIBER-MESH WITH FIBROBLAST GROWTH FACTOR AND STEM CELLS FOR PELVIC FLOOR REPAIR -AN IN VIVO STUDY IN RATS P03.08 Astrid Harpøth. THE REGULATION OF OREXINS AND THEIR COGNATE RECEPTORS IN TWO DISTINCT RAT MODELS OF DEPRESSION AND EFFECTS OF TREATMENTS P03.09 Ditte Thomsen. THE INFLUENCE OF HLA-TYPES ON DISEASE PROGRESSION AMONG HIV-2 INFECTED PATIENTS IN GUINEA-BISSAU P03.10 Jo Simonsen. RETROSPECTIVE DETECTION AND DESCRIPTION OF ACCIDENTAL ABLUMINAL REWIRING AND UNINTENTIONAL CRUSHED STENT SEGMENTS DURING PERCUTANEOUS CORONARY INTERVENTION. THE WRONG INSTENT REWIRING EVALUATION (WIRE) STUDY Poster session 4 Chairmen: Uffe Birk Jensen, Sven Robert Andresen (PhD student), Heidi Buvarp Dyrop (PhD student) & Linda Christie Andrea (PhD student) P04.01 Thomas Lange. IMMUNE MODULATION BY ISCHEMIC PRE-CONDITIONING IN HEALTHY INDIVIDUALS: INTRACELLULAR SIGNALLING IN REGULATORY CELLS (KONDI-IMMUN) P04.02 Sabine Froelich Maarbjerg. PHARMACOKINETICS OF PIPERACILLIN-TAZOBACTAM IN PEDIATRIC ONCOLOGY PATIENTS WITH FEVER AND NEUTROPENIA P04.03 Hannah Brogaard. NEUROPROTECTION BY REMOTE ISCHEMIC POSTCONDITIONING IN NEWBORNS: A PIGLET MODEL OF HYPOXIC ISCHEMIC ENCEPHALOPATHY P04.04 Tua Gyldenholm. HISTONES AND HAEMOSTATIC CHANGES AFTER INTRACRANIAL HAEMORRHAGE P04.05 Nina Elsa Matilda Dabrosin. CHARACTERIZATION OF AN INFLAMMATORY SUBTYPE IN METASTATIC ULCERATED MELANOMA AND ITS RELATION TO PROGNOSIS P04.06 Christine Cramer Christiansen. RISK OF INTERSTITIAL LUNG DISEASE FOLLOWING PIGEON ANTIGEN EXPOSURE: A LONG-TERM FOLLOW-UP STUDY OF PIGEON BREEDERS P04.07 Johannes Enevoldsen. GASTROINTESTINAL TRANSIT TIME IN PATIENTS WITH AQUIRED BRAIN INJURY P04.08 Sofie Malmstrøm. A CLINICAL CHARACTERIZATION OF THE MUSCLE-BONE-UNIT IN PATIENTS WITH NEWLY DIAGNOSED GRAVES' DISEASE COMPARED TO HEALTHY CONTROLS 23

P04.09 Søren Skov. WHAT ARE THE REMODELLING FORCES OF A RIGID MITRAL ANNULOPLASTY RING - A POTENTIAL RISK FACTOR FOR RING DEHISCENCE IN MITRAL VALVE REPAIR? P04.10 Camilla Fox Maule. FOOTPRINT PATTERNS AND FACTURES IN BIORESORBABLE STENTS IMPLANTED IN STEP-DOWN BIFURCATIONS Poster session 5 Chairmen: Helle Prætorius, Anne Wandler (PhD student), Nikolaj Raaber (PhD student) & Marianne von Euler Chelpin (PhD student) P05.01 Litten Sørensen Rossen. A NOVEL INSIGHT INTO THE SIGNAL TRANSDUCTION PATHWAYS OF CD46 P05.02 Rolf Petersen. PROPIONIBACTERIUM ACNES COULD CAUSE PROGRESSIVE MACULAR HYPOMELANOSIS P05.03 Clara Marie Jørgensen. IMMUNODEFICIENCY AND THE LECTIN PATHWAY OF COMPLEMENT P05.04 Josephine Benckendorff. TREATMENT OF AGE-RELATED MACULAR DEGENERATION BY ANTI-VEGF GENE THERAPY P05.05 Natasha Hedemann. THE REGULATION OF MIRNA IN A GENETIC ANIMAL MODEL OF DEPRESSION P05.06 Miriam Højholt. KIM-1 AND MEGALIN INTERACTION - IMPLICATIONS FOR ACUTE KIDNEY INJURY AND REGENERATION P05.07 Christine Ljungberg. CHARACTERIZATION OF IL-17A-MEDIATED IκBζ EXPRESSION P05.08 Stefanie Luecke. INNATE DNA RECOGNITION BY CGAS P05.09 Cecilie Siggaard. THE EFFECT OF TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION IN CHILDREN WITH ENURESIS P05.10 Line Heftdal. IL-26 IN SPONDYLOARTHRITIS Poster session 6 Chairmen: Christian Fynbo Christiansen, Jörg Schullehner (PhD student), Lars Høj Markvardsen (PhD student) & Kristian Ravlo (PhD student) P06.01 Lars Skou Elkjær. COGNITIVE PROBLEMS AMONG CHILDREN EXPOSED TO ANTIEPILEPTIC DRUGS IN PREGNANCY P06.02 Laura Theresa Jørgensen. HERPES SIMPLEX ENCEPHALITIS IN DENMARK: A NATIONWIDE REGISTRY-BASED COHORT STUDY FROM 2004 TO 2014 P06.03 Dennis Graversen. OUT-OF-HOURS TELEPHONE TRIAGE BY NURSES AND DOCTORS IN DANISH ACUTE CARE SETTINGS. A STUDY OF QUALITY FOCUSING ON COMMUNICATION, SAFETY AND EFFICIENCY P06.04 Kristina Larsen. NEONATAL HYPOGLYCEMIA AT NEONATAL INTENSIVE CARE UNIT IN GUINEA BISSAU 24

P06.05 Christina Stilling. HUMAN LEUKOCYTE CLASS II ASSOCIATION WITH INFECTIOUS EVENTS AMONG DANISH BLOOD DONORS P06.06 Nikoline Jensen. THE IMPACT OF SOCIOECONOMIC FACTORS AND GEOGRAPHY ON MORTALITY AMONG PEOPLE WITH MULTIMORBIDITY: A PROSPECTIVE POPULATION- BASED FOLLOW-UP STUDY P06.07 Marie-Louise Ladegaard Baun. ACCESS TO FAST TRANSVAGINAL ULTRASOUND THROUGH GENERAL PRACTICE FOR EARLIER DIAGNOSIS OF OVARIAN CANCER P06.08 Kristian Larsen. DELEGATING HOSPITAL GOVERNANCE TOWARDS HEALTH PROFESSIONALS: TRIAL EVALUATION AND METHODOLOGICAL ISSUES P06.09 Laust Rasmussen. LEFT ATRIAL FUNCTION: A CARDIAC COMPUTED TOMOGRAPHY STUDY OF PATIENTS WITH CHRONIC KIDNEY DISEASE P06.10 Jonas Fynboe Manniche Ebert. DIFFERENTIATED ACCESS TO OUT-OF-HOURS PRIMARY CARE THROUGH EMERGENCY ACCESS Poster session 7 Chairmen: Arne Møller, Line Petersen (PhD student), Trine Majken Gade Bonnesen (PhD student) & Mikkel Petersen (PhD student) P07.01 Simon Sørensen. ANTI-PLATELET AND ANTI-COAGULANT PRESCRIPTIONS AND BREAST CANCER RECURRENCE: A DANISH NATIONWIDE PROSPECTIVE COHORT STUDY P07.02 Anne Sofie Krogh Holdam. BIOLOGICAL THERAPY NORMALISE THE HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE AFTER SIX MONTHS P07.03 Anne-Mette Kristensen. A STUDY OF THE REGULATORY PROTEIN CD83 AND ITS LIGAND IN RHEUMATOID ARTHRITIS P07.04 Jelmer Sybren Westra. WIRE-FREE INVASIVE FUNCTIONAL IMAGING (WIFI-2) P07.05 Mai-Britt Worm Ørntoft. PERFORMANCE OF THE COLORECTAL CANCER SCREENING MARKER SEPT9 IS INFLUENCED BY AGE, DIABETES AND ARTHRITIS: A NESTED CASE CONTROL STUDY P07.06 Louise Steinmüller. HIGH PERCENTAGES OF ALDH BR CELLS ARE COMMON IN MYELODYSPLASTIC SYNDROME P07.07 Stine Bak. AN INTERGENERATIONAL EPIGENETIC STUDY OF THE ASSOCIATION BETWEEN MATERNAL LOW-GRADE INFLAMMATION AND OFFSPRING OBESITY P07.08 Emma Lise Jakobsen. NECK-SHOULDER PAIN AND EMPLOYMENT AMONG FORMER SEWING MACHINE OPERATORS - A FOLLOW-UP STUDY P07.09 Gunhild Mo Hansen. CHANGES IN THE SHOULDER FUNCTION AFTER CONSTRAINT- INDUCED MOVEMENT THERAPY (CIMT) 25

Poster session 8 Chairmen: Holger Brüggemann, Xianwei Zhang (PhD student), Christian F. P. Scholz (PhD student) & Omar Majed Abuyaman (PhD student) P08.01 Juan Yuan. IN VITRO DIFFERENTIATION OF HUMAN NEURAL PROGENITOR CELLS INTO STRIATAL GABAERGIC NEURONS P08.02 Karthiga Thavachelvam. RECOMBINANT OAS PROTEINS PROHIBIT HIV INFECTION P08.03 Dmitrii Kamaev. EFFECTS OF HETEROZYGOUS TMEM16A-KNOCKOUT IN MICE VASCULATURE P08.04 Steen Fagerberg. P2X RECEPTOR INHIBITION PROTECTS THP-1 MONOCYTES AGAINST CYTOLYSIS BY A-HAEMOLYSIN FROM ESCHERICHIA COLI AND LEUKOTOXIN FROM AGGREGATIBACTER ACTINOMYCETEMCOMITANS P08.05 Mikkel Carstensen Gjelstrup. MONONUCLEAR CELLS IN MULTIPLE SCLEROSIS: AN ANALYSIS OF MONOCYTES AND B-CELLS AND THEIR ROLE IN DISEASE ACTIVITY P08.06 Casper Larsen. STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF COBALAMIN UPTAKE AND TRANSPORT P08.07 Hong Sain Ooi. A FLEXIBLE SCORING SCHEME TO ASSESS THE RELIABILITY AND RELATEDNESS OF MOLECULAR INTERACTION NETWORK P08.08 Rasmus Hansen Olesen. OBESITY AND AGE-RELATED ALTERATIONS IN THE GENE EXPRESSION OF ZINC-TRANSPORTER-PROTEINS IN THE HUMAN BRAIN P08.09 Stine Rahbek. HOW DOES THE PRODUCER CELL AFFECT HSV INDUCED IMMUNITY? P08.10 Martin Lund. BEZAFIBRATE IN RARE DISORDERS Poster session 9 Chairmen: Jeppe Prætorius, Lilliana Beck (PhD student), Stig Hill Christiansen (PhD student) & Kasper Fjellhaugen Hjuler (PhD student) P09.01 Martin Brandhøj Skov. DIVALENT CATION-RESPONSIVE MYOTONIA AND MUSCLE PARALYSIS IN SKELETAL MUSCLE SODIUM CHANNELOPATHY P09.02 Anders Laustsen A NOVEL EX VIVO HUMAN PLASMACYTOID DENDRITIC CELL MODEL FOR USE IN INNATE IMMUNOLOGY P09.03 Didde Haslund. IDENTIFICATION AND MODELING OF HEREDITARY ANGIOEDEMA DISEASE MECHANISMS BY GENETIC ENGINEERING IN PATIENT-DERIVED CELLS P09.04 Marie-Louise Holm. APOLIPOPROTEIN E ISOFORM-SPECIFIC EFFECTS ON THE LEVEL AND DISTRIBUTION OF LRP1 AND ENDOCYTIC TRAFFICKING OF Aβ IN THE MOUSE HIPPOCAMPUS P09.05 Camilla Darum Sørensen. MYELOID-DERIVED SUPPRESSOR CELLS IN ALLOGENEIC STEM CELL TRANSPLANTATION P09.06 Sara Konstantin Nissen. ROLE OF INNATE DNA SENSING IN BLOOD CD4+ T CELLS DURING HIV INFECTION 26

P09.07 Willemijn Comuth. THE EFFECT OF DABIGATRAN ON THROMBIN GENERATION ASSAY IN VITRO P09.08 Sidsel Rødgaard-Hansen. EFFECTS OF LIFE-STYLE INTERVENTION ON SOLUBLE CD163, A MACROPHAGE ACTIVATION MARKER, IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE P09.09 Yan Zhou. FEEDER-FREE DERIVATION AND LINEAGE COMMITMENT OF FUNCTIONAL MESENCHYMAL STEM CELLS DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS P09.10 Niels Sanderhoff Degn. CAN SORCS2 MODULATE BDNF SIGNALING AND DISEASE PROGRESSION IN HUNTINGTON S DISEASE? Poster session 10 Chairmen: Mette Madsen, Michael Aagaard Andersen (PhD student), Trine Maxel Juul (PhD student) & Maria do Nascimento Lopes Primo (PhD student) P10.01 Emil Hagen Ernst. DORMANCY AND ACTIVATION OF HUMAN OOCYTES: COMPARISONS OF TRANSCRIPTOMES FROM THE DORMANT AND ACTIVATED HUMAN OOCYTE VIA NEXT GENERATION SEQUENCING P10.02 Aisha Rafique. DEVELOPMENT AND MODIFICATION OF TRIOLEIN-POPC AND BIOACTIVE 1,25 VITAMIN D3- ENCAPSULATED NANOPARTICLE FOR ANTI- INFLAMMATORY THERAPY TARGETED TO MACROPHAGES IN VITRO AND IN VIVO P10.03 Mette Christensen. [CA 2+ ] I OSCILLATIONS AND IL-6 RELEASE INDUCED BY α- HAEMOLYSIN FROM ESCHERICHIA COLI REQUIRE P2 RECEPTOR ACTIVATION IN RENAL EPITHELIA P10.04 Johan Vad-Nielsen. CROSSTALK BETWEEN EPIGENETICS AND ALTERNATIVE SPLICING IN CANCER EPITHELIAL-MESENCHYMAL TRANSITION (EMT) P10.05 Rasmus Pihl. A MATURASE IN THE ALTERNATIVE PATHWAY OF THE COMPLEMENT SYSTEM P10.06 Bodil Gade Hornstrup. OBSTRUCTIVE SLEEP APNEA AND BLOOD PRESSURE IN PATIENTS WITH HYPERTENSION AND CHRONIC KIDNEY DISEASE, STAGE 2 P10.07 Rikke Hahn Kofoed. INVESTIGATING THE ROLE OF POLO-LIKE KINASE 2 (PLK-2) IN THE REGULATION OF α-synuclein (AS) PROTEIN LEVELS P10.08 Sara Buskbjerg Jager. NEW TREATMENTS FOR NEUROPATHIC PAIN: ANALYZING SATELLITE GLIAL CELLS P10.09 Pernille Thomasen. THE FUNCTION OF SORCS2 IN MOTOR NEURON DEVELOPMENT P10.10 Rasmus Søndergaard Aagaard. CARDIAC ULTRASONOGRAPHY FOR DETECTION OF PULMONARY EMBOLISM DURING CARDIAC ARREST - A RANDOMIZED PORCINE STUDY 27

Poster session 11 Chairmen: Anne Landau, Maiken Ina Siegismund Kjærsgaard (PhD student), Peter Breining (PhD student) & Susanne Friis Søndergård (PhD student) P11.01 Sidsel Boie. CONTINUED VERSUS DISCONTINUED OXYTOCIN STIMULATION OF LABOUR IN A DOUBLE-BLIND RANDOMISED CONTROLLED TRIAL P11.02 Signe Timm. THE URBAN-RURAL GRADIENT IN ASTHMA: A POPULATION-BASED COHORT STUDY IN NORTHERN EUROPE P11.03 Hanan Amadid. WHICH PHYSICAL ACTIVITY PATTERNS PREVENT DIABETES AND CARDIOVASCULAR DISEASE IN PEOPLE WITH ELEVATED DIABETES RISK? A REGISTER- BASED FOLLOW-UP STUDY OF THE ASSOCIATION OF PHYSICAL ACTIVITY WITH DIABETES AND CARDIOVASCULAR DISEASE: THE ADDITION-PRO STUDY P11.04 Sascha Pilemann-Lyberg. EFFECT OF DIETARY PROTEIN RESTRICTION AND URIC ACID ON PROGRESSION OF DIABETIC NEPHROPATHY P11.05 Jens Hartlev. PLATELET RICH FIBRIN (PRF) MEMBRANES IN LATERAL ALVEOLAR RIDGE AUGMENTATION P11.06 Anne Bendix Andersen. THE PUZZLE OF COHERENCE - AN ETHNOGRAPHIC INSPIRED STUDY ABOUT CROSS-SECTORIAL COLLABORATION IN DANISH HEALTH CARE P11.07 Morten Overgaard. THE PSEUDO-OBSERVATION METHOD IN HEALTH SCIENCE: AN INTRODUCTION P11.08 Louise Bang Grode. CELIAC DISEASE AND INFERTILITY AMONG MEN AND WOMEN IN DENMARK P11.09 Nasrin Tayyari Dehbarez. HOSPITAL CHOICE IN TIMES OF RESTRUCTURING THE HOSPITAL SECTOR; ASSESSMENT OF INDIVIDUAL PREFERENCES FOR THE CASE OF UNCOMPLICATED PREGNANCIES P11.10 Signe Toft Andersen. THE MACROPHAGE ACTIVATION MARKER SOLUBLE CD163 IS ASSOCIATED TO DIABETIC NEUROPATHY - A CROSS-SECTIONAL STUDY Poster session 12 Chairmen: Yuelian Sun, Kirstine Høj Obling (PhD student), Erhard Næss-Schmidt (PhD student) & Susanne Hvolgaard Mikkelsen (PhD student) P12.01 Anders Mark Christensen. POUCH FAILURES AFTER ILEAL POUCH-ANAL ANASTOMOSIS OVER THREE DECADES IN A NATIONAL COHORT P12.02 Simon Riis. METABOLIC AND PERFORMANCE RELATED EFFECTS OF AN EXERCISE STRATEGY TO IMPROVE FAT OXIDATION DURING EXERCISE IN HUMANS - DESCRIPTION OF STUDY DESIGNS P12.03 Martin Langeskov Christensen. EFFECTS OF AEROBIC EXERCISE ON BRAIN HEALTH IN PEOPLE WITH MULTIPLE SCLEROSIS P12.04 Chalotte Willemann Stecher. THE MALI SCHISTOSOMIASIS MORBIDITY STUDY - MASCHISMO 28

P12.05 Pernille Falberg Rønn. ETHNIC DIFFERENCES IN ANTHROPOMETRIC MEASURES AND ABDOMINAL FAT DISTRIBUTION: A CROSS-SECTIONAL STUDY IN INUIT, AFRICANS AND EUROPEANS P12.06 Vibe Bolvig Hyldgård. UNDERSTANDING THE NEW GOAL FOR DANISH HEALTH CARE: HIGHER QUALITY AND BETTER OUTCOMES FOR THE SAME COSTS - THE CASE OF STROKE P12.07 Mai-Britt Hägi-Pedersen. PREHOMECARE - EFFECT OF PREHOMECARE WITH PRETERM INFANTS USING VIDEOCONFERENCING AND SMARTPHONE APPLICATION P12.08 Katrine Fuglsang. STAGING IN CERVICAL CANCER CONTINUOUSLY BASED ON A CLINICAL EXAMINATION P12.09 Karen Busk Nørøxe. BURNOUT AND CLINICAL PRACTICE AMONG DANISH GENERAL PRACTITIONERS P12.10 Rikke Aarhus. FAST-TRACK DIAGNOSTICS: SOCIAL AND MORAL DILEMMAS OF CANCER PATHWAYS Poster session 13 Chairmen: Karl-Anton Dorph-Petersen, Liv Solvår Nymark (PhD student), Yuduo Zheng (PhD student) & Sara Marie Hebsgaard Offersen (PhD student) P13.01 Lasse Bjerg Hansen. CLUSTERING OF MICROVASCULAR AND MACROVASCULAR COMPLICATIONS IN TYPE 1 DIABETES P13.02 Julie Lyngsø. DOES LIFESTYLE IMPACT ON THE SUCCESS OF ASSISTED REPRODUCTION? P13.03 Oana-Veronica Frederiksen. POST-TRAUMATIC HEADACHE IN YOUNG PEOPLE AFTER CONCUSSION P13.04 Mads Sørensen Larsen. NUTRITION STRATEGIES TO OPTIMIZE HEALTH AND PERFORMANCE IN RELATION TO TRAINING P13.05 Kamilla Pedersen. PSYCHSIM - RESHAPING LEARNING EXPERIENCES IN PSYCHIATRIC TEACHING P13.06 Mette Høj Lauridsen. CEREBRAL BOLD AND T2* MEASUREMENTS IN NORMAL PREGNANCIES AND IN PREGNANCIES COMPLICATED BY FETAL CONGENITAL HEART DISEASE P13.07 Ditte H. Jensen. CAN PSYCHOLOGICAL TREATMENT BE DELIVERED OVER THE INTERNET? A NEW TREATMENT APPROACH FOR HEALTH ANXIETY P13.08 Jette Schilling Larsen. TRANSITION IN INFANTS - FROM MILK TO SOLID FOODS: AN ACTION RESEARCH PROJECT ON HEALTH VISITORS PRACTICE P13.09 Kirsten Høj FITNESS TESTING IN PREVENTIVE HEALTH CHECKS - A MOTIVATOR FOR CHANGING PHYSICAL ACTIVITY BEHAVIOR? P13.10 Bettina Kjær Kristiansen. THE EFFECT OF GP REMINDERS ON FOLLOW-UP OF CERVICAL CANCER SCREENING TEST 29

Poster session 14 Chairmen: Søren Dinesen Østergaard, Louise Kærholm Schæbel (PhD student) & Anneli Clea Skjelmose Bolund (PhD student) P14.01 Sara Francis. IDENTIFYING THE RIGHT KIND OF SUPPORT FOR SPOUSES CARING FOR A LOVED ONE WITH A PRIMARY BRAIN TUMOUR P14.02 Tina Wang Vedelø. IDENTIFYING THE NEEDS OF DANISH BRAIN TUMOR PATIENTS P14.03 Cecilie Nørby Thisted. WORK PARTICIPATION OF EMPLOYEES WITH DEPRESSION ASSUMING A WORKPLACE PERSPECTIVE: A SYSTEMATIC MIXED STUDIES REVIEW - PRELIMINARY RESULTS P14.04 Anita Tønder Nielsen. INADEQUATE CANCER DIAGNOSTICS AMONG PERSONS WITH SEVERE MENTAL ILLNESS: A POPULATION-BASED COHORT STUDY P14.05 Belle Mia Loft. NURSES EXPERIENCES OF THEIR ROLE IN THE INTERDISCIPLINARY STROKE TEAM P14.06 Dinesh Neupane. PREVALENCE, AWARENESS, TREATMENT, CONTROL AND BEHAVIORAL RISK FACTORS OF HYPERTENSION IN LEKHNATH MUNICIPALITY, A SEMI- URBAN AREA OF NEPAL P14.07 Jakob Søgaard Juul. USE OF IMMUNOCHEMICAL FAECAL OCCULT BLOOD TEST IN GENERAL PRACTICE ON PATIENTS PRESENTING UNCHARACTERISTIC SYMPTOMS OF COLORECTAL CANCER: A PILOT STUDY P14.08 Trine Ellegaard. PATIENT CONTROLLED ADMISSIONS IN PSYCHIATRY - A NATIONAL EXPLORATIVE STUDY OF THE PATIENT AND THE HEALTH PROFESSIONALS' PERSPECTIVE P14.09 Mette Lise Lousdal. EFFECT OVER TIME OF ORGANIZED MAMMOGRAPHY SCREENING ON STAGE-SPECIFIC INCIDENCE IN DENMARK: A POPULATION STUDY P14.10 Anders Prior. THE IMPACT OF STRESS ON MORTALITY AMONG PEOPLE WITH MULTIMORBIDITY: A PROSPECTIVE POPULATION-BASED COHORT STUDY Poster session 15 Chairmen: Peter Bross, Ida Skødt Jensen (PhD student), Peter Skov Jensen (PhD student) & Lea Ladegaard Grønkjær (PhD student) P15.01 Vicki Trier Taasti. IMPROVED PROTON STOPPING POWER RATIO ESTIMATION FOR A DEFORMABLE 3D DOSIMETER USING DUAL ENERGY CT P15.02 Mette Tranberg Nielsen. IMPLEMENTATION OF HPV SELF-SAMPLING TO INCREASE PARTICIPATION RATE IN CERVICAL CANCER SCREENING P15.03 Line Khalidan Vibholm. TOLL-LIKE RECEPTOR 9 ENHANCEMENT OF ANTIVIRAL IMMUNITY IN CHRONIC HIV-1 INFECTION: A PHASE 1B/2A TRIAL - TEACH P15.04 Anders Abildgaard. ANTI-DEPRESSANT EFFECT OF PROBIOTICS: A METABOLOMIC ANALYSIS 30

P15.05 Charlotte Stephansen. ASSOCIATION BETWEEN RIGHT VENTRICULAR LEAD POSITION AND CLINICAL OUTCOME IN CARDIAC RESYNCHRONIZATION THERAPY: VALIDATION BY CARDIAC COMPUTED TOMOGRAPHY P15.06 Sarah Østrup Jensen. NOVEL BLOOD-BASED BIOMARKERS FOR EARLY DETECTION OF COLORECTAL CANCER P15.07 Jenny Diana Grove. VITAMIN D SUPPLEMENTATION TO PATIENTS WITH GRAVES' DISEASE: A RANDOMIZED CLINICAL TRIAL P15.08 Stine Overvad Fredslund. ANTICANCER TREATMENT OF BREAST CANCER RELATED TO CARDIOTOXICITY AND DYSFUNCTIONAL ENDOTHELIUM - THE ABCDE STUDY P15.09 Kasper Adelborg. MORTALITY RISK AMONG HEART FAILURE PATIENTS WITH DEPRESSION: A NATIONWIDE POPULATION-BASED COHORT STUDY P15.10 Martin Bøhme Rasmussen. DIAGNOSTIC PERFORMANCE AND SYSTEM DELAY USING TELEMEDICINE FOR PRE-HOSPITAL DIAGNOSIS IN TRIAGING AND TREATMENT OF STEMI Poster session 16 Chairmen: Jakob Blicher, Peter Agger (PhD student) & Lise Maria Lindahl (PhD student) P16.01 Amanda Eskelund. ANTIDEPRESSANTS IMPACT KYNURENINE METABOLISM DIFFERENTLY: A COMPARATIVE STUDY OF VORTIOXETINE, FLUOXETINE AND KETAMINE IN RATS P16.02 Anne-Mette Oxvig. TOWARDS PROFILING OF METHYLGLYOXAL MODIFIED AMINO ACID RESIDUES IN CELLS P16.03 Nina Munk Lyhne. INCIDENCE OF AND SURVIVAL AFTER GLOTTIC SQUAMOUS CELL CARCINOMA IN DENMARK FROM 1971 TO 2011 - A REPORT FROM THE DAHANCA GROUP P16.04 Emil Christensen. INDIVIDUALIZED DISEASE MONITORING USING DEEP TARGETED SEQUENCING OF CIRCULATING TUMOR DNA IN PATIENTS WITH ADVANCED BLADDER CANCER P16.05 Nanna-Sophie Brinck-Jensen. CELLULAR IMMUNITY IN CHRONIC HEPATITIS B: CHARACTERIZING AND BREAKING THE IMMUNE TOLERANCE P16.06 Mai-Britt Bjørklund Ellegaard. HOSPITALBASED FOLLOW-UP AFTER PRIMARY BREAST CANCER TREATMENT P16.07 Nichlas Riise Jespersen. THE ROLE OF MITOCHONDRIA IN THE PROTECTION AGAINST MYOCARDIAL ISCHEMIA-REPERFUSION INJURY AT ONSET DIABETES P16.08 Stine Gunnersen. ROLE OF CCL2 EXPRESSED BY SMOOTH MUSCLE CELLS DURING INITIATION OF ATHEROSCLEROSIS P16.09 Pernille Gabel. EFFECT OF A DECISION AID IN THE DANISH NATIONAL COLORECTAL CANCER SCREENING PROGRAMME: A RANDOMISED CONTROLLED TRIAL AMONG CITIZENS WITH LOWER EDUCATIONAL ATTAINMENT IN THE CENTRAL DENMARK REGION 31

P16.10 Anita Tranberg Simonsen. CHANGES IN CLONAL ARCHITECTURE IN AML PATIENTS UPON CHEMOTHERAPEUTIC TREATMENT Poster session 17 Chairmen: Jens Christian Djurhuus, Torbjørn Brøgger (PhD student) & Rune Wilkens (PhD student) P17.01 Mathilde Borg Houlberg Thomsen. SPATIAL AND TEMPORAL CLONAL HETEROGENEITY IN ADVANCED BLADDER CANCER - IMPLICATIONS FOR TARGETED THERAPY P17.02 Shun-Ichi Suzuki. HEMODYNAMICS IN PAINFUL CRANIOFACIAL MUSCLES; INFLUENCE OF GLUTAMATE EVOKED PAIN ON BLOOD OXYGENATION P17.03 Lena-Sophie Martis. DEPRESSIVE-LIKE RATS SHOW IMPAIRED LEARNING OF A COMPLEX RODENT TOUCHSCREEN TASK P17.04 Anne Ramlov. CLINICAL SIMULATION OF NODAL BOOSTING IN CERVIX CANCER USING REDUCED MARGIN AND COVERAGE PROBABILITY P17.05 Oscar Casares Magaz. SPATIAL RECTAL DOSE-RESPONSE FOR PATIENT-REPORTED LEAKAGE, OBSTRUCTION, AND URGENCY IN PROSTATE RADIOTHERAPY P17.06 Anders Valdemar Edhager. ASSESSMENT OF OXIDATIVE STRESS IN METABOLIC DISORDERS BY MASS SPECTROMETRY OF PEROXIREDOXINS P17.07 Ninna Cathrine Schmidt Voss. BLOOD PERFUSION IN HUMAN COLON CANCER P17.08 Morten Møbjerg Callesen. DEVELOPMENT AND CHARACTERIZATION OF COLORECTAL AND UROTHELIAL CELL CARCINOMA PIG MODELS P17.09 Sandra Maria Skovdal. ANTIBIOTIC SUSCEPTIBILITY IS RESTORED BY ULTRA-DENSE POLY(ETHYLENE GLYCOL) COATING OF MEDICAL IMPLANTS P17.10 Iben Lyskjær. NON-INVASIVE ANALYSIS OF TUMOR EVOLUTION USING CIRCULATING TUMOR DNA Poster session 18 Chairmen: Lise Lotte Hansen, Kristina Margareta Öbrink-Hansen (PhD student) & Laura Ozer Kettner (PhD student) P18.01 Mette Kragh. PATIENTS' EXPERIENCES WITH WAKE AND LIGHT THERAPY P18.02 Line Staun. FLUORIDE IN REGION-SPECIFIC DENTAL BIOFILM P18.03 Line M. Hybel Schack. RADIATION-INDUCED MORBIDITY EVALUATED BY HIGH- FREQUENCY ULTRASOUND: A PILOT STUDY P18.04 Kim Sivesgaard. DWIBS IMPROVES THE DETECTION OF EXTRA HEPATIC COLORECTAL CANCER METASTASES P18.05 Christian Andreas Hvid. ACCURACY OF SOFTWARE-ASSISTED CONTOUR PROPAGATION FROM PLANNING CT TO CONE-BEAM CT IN HEAD AND NECK P18.06 Ditte Løhmann. AGE AND BODY-WEIGHT IS ASSOCIATED WITH SEVERE ADVERSE EVENTS AND SURVIVAL IN PEDIATRIC ACUTE MYELOID LEUKEMIA 32

P18.07 Jenny Bertholet. REAL-TIME LIVER MOTION MONITORING ON CONVENTIONAL LINAC BY EXTERNAL SURROGATE AND SPARSE KV IMAGING P18.08 Katrine Hygum. THE EFFECT OF LIRAGLUTIDE ON BONE TURNOVER, BONE MASS AND BONE CELL FUNCTION P18.09 Tommy Kragh Bechsgaard. BIOMECHANICAL DESCRIPTION OF AORTIC ROOT REPAIR PROCEDURES, AN IN VITRO EXPERIMENT P18.10 Kailash Rani. DEVELOPMENT AND VALIDATION OF METHODS FOR NEAR PATIENT MEASUREMENT OF DRUGS USING THE "DNA STRAND - DISPLACEMENT COMPETITION REACTION" Poster session 19 Chairmen: Michael Mulvany, Mark Klitgaard Nøhr (PhD student) & Jeppe Bakkestrøm Rosenbæk (PhD student) P19.01 Andreas Nørgaard Glud. PROTEIN AGGREGATION MODELS OF PARKINSON S DISEASE USING VIRAL VECTORS, PROTEASOME INHIBITION AND INOCULATION OF PREFORMED FIBRILS IN THE GÖTTINGEN MINIPIG CNS P19.02 Anne Bo. DEVELOPMENT OF AN EVIDENCE- AND THEORY-BASED INTERVENTION FOR YOUNG ADULTS WITH TYPE 2 DIABETES P19.03 Iben Rahbek Andersen. RADIOFREQUENCY ABLATION OF COLORECTAL LIVER METASTASES: LONG-TERM SURVIVAL P19.04 Mette Marie Fode. SURVIVAL AND PROGNOSTIC FACTORS IN 321 PATIENTS TREATED WITH STEREOTACTIC BODY RADIOTHERAPY FOR OLIGOMETASTASES P19.05 Jacob Kinggaard Lilja-Fischer. PATIENT-DERIVED XENOGRAFTS OF OROPHARYNGEAL SQUAMOUS CELL CARCINOMA: ESTABLISHMENT AND CHARACTERIZATION P19.06 Jakob Toftegaard. A SIMULATION STUDY OF HYBRID MLC AND COUCH TRACKING P19.07 Steffen Filskov Sørensen. DETECTION OF SOLUBLE PROGRAMMED CELL DEATH RECEPTOR-1 IN PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER P19.08 Rasmus Stilling Tougaard. IN VIVO VISUALIZATION OF METABOLIC FLUX IN HEART FAILURE USING HYPERPOLARIZED MAGNETIC RESONANCE P19.09 Rasmus Kold-Christensen. ORGANIC REACTION BASED CAPTURE ELISA P19.10 Caroline Marie Andreasen. CHRONIC NON-BACTERIAL OSTEOMYELITIS TREATED WITH PAMIDRONATE IN A RANDOMISED PLACEBO- CONTROLLED CLINICAL TRIAL (CNOPAM) Poster session 20 Chairmen: Michael R. Horsman, Mette Bohl Larsen (PhD student) & Esben Ahlburg Eickhardt (PhD student) P20.01 Louise Stride Nielsen. STABILITY OF COCAINE ALKALOIDS AND RESIDUAL SOLVENTS APPLIED IN DRUG PROFILING 33