Kit components. MagaZorb DNA Mini-Prep Kit, 800 preps. Proteinase K Solution, 20mg/ml

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07/05/2016 Kit components Product code MB1008 Components: MC500 MC501 MC502 MC503 MC504 MC505 Description MagaZorb DNA Mini-Prep Kit, 800 preps Proteinase K Solution, 20mg/ml Lysis Buffer Binding Buffer MagaZorb Reagent Wash Buffer Elution Buffer

Page 1/7 Printing date 05.07.2016 Revision: 30.06.2016 * 1 Identification Product identifier Trade name: Proteinase K Solution, 20mg/ml Article number: MC500 Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the preparation: Laboratory chemicals Details of the supplier of the safety data sheet Manufacturer/Supplier: Promega Corporation 2800 Woods Hollow Road Madison, WI 53711 U.S.A. 1-608-274-4330 1-800-356-9526 SDS author: Regulatory.Affairs@promega.com Further information obtainable from: Promega Pte Ltd 77 Science Park Drive 02-16 Cintech III Singapore Science Park I 118256 Singapore Tel: (65) 6513 3450 Fax: (65) 6773 5210 E-mail Address: sg_custserv@promega.com SDS author: regulatory_affairs@promega.com Emergency telephone number: For Chemical Emergency Spill, Leak, Fire, Exposure, or Accident Call CHEMTREC Day or Night. Within Singapore +800-101-2201 Within USA and Canada: 1-800-424-9300 Outside USA and Canada: +1 703-527-3887 (collect calls accepted). * 2 Hazards identification Classification of the substance or mixture health hazard Resp. Sens. 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. Label elements GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS). Hazard pictograms GHS08 (Contd. on page 2)

Page 2/7 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Proteinase K Solution, 20mg/ml Signal word Danger Hazard-determining components of labelling: Proteinase, Tritirachium album serine Hazard statements May cause allergy or asthma symptoms or breathing difficulties if inhaled. Precautionary statements [In case of inadequate ventilation] wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Dispose of contents/container in accordance with local/regional/national/international regulations. Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. (Contd. of page 1) * 3 Composition/information on ingredients Chemical characterisation: Mixtures Description: The product is a mixture of the hazardous substances listed below along with unlisted nonhazardous substances. Components: 39450-01-6 Proteinase, Tritirachium album serine <2.50% Resp. Sens. 1, H334; Skin Irrit. 2, H315; Eye Irrit. 2A, H319; STOT SE 3, H335 Additional information: For the wording of the listed hazard phrases refer to section 16. * 4 First-aid measures Description of first aid measures After inhalation: Supply fresh air and to be sure call for a doctor. In case of unconsciousness place patient stably in side position for transportation. After skin contact: Generally the product does not irritate the skin. After eye contact: Rinse opened eye for several minutes under running water. After swallowing: If the patient feels unwell or is concerned, obtain medical advice. Information for doctor: Most important symptoms and effects, both acute and delayed Allergic reactions Indication of any immediate medical attention and special treatment needed No further relevant information available. 5 Fire-fighting measures Extinguishing media Suitable extinguishing agents: CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Special hazards arising from the substance or mixture None known Advice for firefighters No special advice. (Contd. on page 3)

Page 3/7 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Proteinase K Solution, 20mg/ml (Contd. of page 2) * 6 Accidental release measures Personal precautions, protective equipment and emergency procedures Remove persons from danger area. Wear protective clothing. Environmental precautions: Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and material for containment and cleaning up: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Dispose contaminated material as waste according to Section 13. Ensure adequate ventilation. Reference to other sections See Section 7 for information on safe handling See Section 13 for disposal information. 7 Handling and storage Handling Precautions for safe handling Keep receptacles tightly sealed. Ensure good ventilation/exhaustion at the workplace. Prevent formation of aerosols. Work only in fume cupboard. Information about fire - and explosion protection: Keep respiratory protective device available. Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. Specific end use(s) No further relevant information available. * 8 Exposure controls/personal protection Additional information about design of technical facilities: No further data; see item 7. Control parameters Ingredients with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists valid during the making were used as basis. Exposure controls Personal protective equipment General protective and hygienic measures Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing Wash hands before breaks and at the end of work. Do not eat or drink while working. Respiratory protection: In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device. (Contd. on page 4)

Page 4/7 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Proteinase K Solution, 20mg/ml (Contd. of page 3) Protection of hands: Protective gloves. Select the glove material considering penetration time, rate of diffusion and degradation time. The selected protective gloves must satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it or AS/NZS 2161. Material of gloves: The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Eye protection: Safety glasses Use equipment for eye protection tested and approved under government standard EN 166(EU) or AS/NZS 1336, 1137 and 1138. * 9 Physical and chemical properties Information on basic physical and chemical properties General Information Appearance: Form: Fluid Colour: Colourless Odour: Not determined Odour threshold: ph-value at 20 C: 7.2 Change in condition Melting point/melting range: undetermined Boiling point/boiling range: undetermined Flash point: > 100 C Flammability (solid, gaseous) Not applicable. Ignition temperature: 400 C Decomposition temperature: Self-igniting: Product is not selfigniting. Danger of explosion: Product does not present an explosion hazard. Explosion limits: Lower: 0.9 Vol % Upper: 0.0 Vol % Vapour pressure at 20 C: 0.1 hpa Density: Not determined Relative density Vapour density Evaporation rate Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: kinematic: Organic solvents: 50.0 % (Contd. on page 5)

Page 5/7 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Proteinase K Solution, 20mg/ml Water: 47.8 % Other information No further relevant information available. (Contd. of page 4) * 10 Stability and reactivity Reactivity No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Possibility of hazardous reactions No dangerous reactions known Conditions to avoid No further relevant information available. Incompatible materials: No further relevant information available. Hazardous decomposition products: No dangerous decomposition products known * 11 Toxicological information Information on toxicological effects Acute toxicity LD/LC50 values relevant for classification: No data available Primary irritant effect: Skin corrosion/irritation No irritant effect. Serious eye damage/irritation Irritating effect. Respiratory or skin sensitisation Sensitisation possible through inhalation. Additional toxicological information: The product shows the following dangers according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest version. Harmful * 12 Ecological information Toxicity Aquatic toxicity: Not harmful to the aquatic environment Persistence and degradability: Not available Behaviour in environmental systems: Bioaccumulative potential Not known Mobility in soil No further relevant information available. Ecotoxical effects: Remark: Not available Additional ecological information: General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. Other adverse effects No further relevant information available. (Contd. on page 6)

Page 6/7 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Proteinase K Solution, 20mg/ml (Contd. of page 5) * 13 Disposal considerations Waste treatment methods Recommendation Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: Handling and Storage and Section 8: Exposure Control/Personal Protection for additional handling information and protection of employees. Uncleaned packaging: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agents: Water, if necessary together with cleansing agents. * 14 Transport information UN-Number ADR, ADN, IMDG, IATA UN proper shipping name ADR, ADN, IMDG, IATA Transport hazard class(es) ADR, ADN, IMDG, IATA Class Packing group ADR, IMDG, IATA Environmental hazards: Marine pollutant: Special precautions for user Not hazardous for transportation None None None No Not applicable. Transport in bulk according to Annex II of Marpol and the IBC Code Not applicable. UN "Model Regulation": * 15 Regulatory information Safety, health and environmental regulations/legislation specific for the substance or mixture GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS). Signal word Danger Hazard-determining components of labelling: Proteinase, Tritirachium album serine Hazard statements May cause allergy or asthma symptoms or breathing difficulties if inhaled. Precautionary statements [In case of inadequate ventilation] wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Dispose of contents/container in accordance with local/regional/national/international regulations. (Contd. on page 7)

Page 7/7 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Proteinase K Solution, 20mg/ml Directive 2012/18/EU Named dangerous substances - ANNEX I None of the ingredients is listed. (Contd. of page 6) National regulations Waterhazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water. Chemical safety assessment: A Chemical Safety Assessment has not been carried out. 16 Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing SDS: Promega Corporation Safety Department 2800 Woods Hollow Road Madison, WI 53711 U.S.A. Abbreviations and acronyms: RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association EINECS: European Inventory of Existing Commercial Chemical Substances ELINCS: European List of Notified Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent PBT: Persistent, Bioaccumulative and Toxic vpvb: very Persistent and very Bioaccumulative Skin Irrit. 2: Skin corrosion/irritation Category 2 Eye Irrit. 2A: Serious eye damage/eye irritation Category 2A Resp. Sens. 1: Respiratory sensitisation Category 1 STOT SE 3: Specific target organ toxicity (single exposure) Category 3 * Data compared to the previous version altered.

Page 1/8 Printing date 05.07.2016 Revision: 30.06.2016 * 1 Identification Product identifier Trade name: Lysis Buffer Article number: MC501 Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the preparation: Laboratory chemicals Details of the supplier of the safety data sheet Manufacturer/Supplier: Promega Corporation 2800 Woods Hollow Road Madison, WI 53711 U.S.A. 1-608-274-4330 1-800-356-9526 SDS author: Regulatory.Affairs@promega.com Further information obtainable from: Promega Pte Ltd 77 Science Park Drive 02-16 Cintech III Singapore Science Park I 118256 Singapore Tel: (65) 6513 3450 Fax: (65) 6773 5210 E-mail Address: sg_custserv@promega.com SDS author: regulatory_affairs@promega.com Emergency telephone number: For Chemical Emergency Spill, Leak, Fire, Exposure, or Accident Call CHEMTREC Day or Night. Within Singapore +800-101-2201 Within USA and Canada: 1-800-424-9300 Outside USA and Canada: +1 703-527-3887 (collect calls accepted). * 2 Hazards identification Classification of the substance or mixture Acute Tox. 4 H302 Harmful if swallowed. Skin Irrit. 2 H315 Causes skin irritation. Eye Irrit. 2A H319 Causes serious eye irritation. (Contd. on page 2)

Page 2/8 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Lysis Buffer (Contd. of page 1) Label elements GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS). Hazard pictograms GHS07 Signal word Warning Hazard-determining components of labelling: guanidinium chloride Hazard statements Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Precautionary statements Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. * 3 Composition/information on ingredients Chemical characterisation: Mixtures Description: The product is a mixture of the hazardous substances listed below along with unlisted nonhazardous substances. Components: 50-01-1 guanidinium chloride 25-50% Acute Tox. 4, H302; Skin Irrit. 2, H315; Eye Irrit. 2, H319 151-21-3 sodium dodecyl sulphate <2.00% Flam. Sol. 1, H228; STOT SE 2, H371; Eye Dam. 1, H318; Aquatic Chronic 2, H411; Acute Tox. 4, H302; Acute Tox. 4, H332; Skin Irrit. 2, H315 Additional information: For the wording of the listed hazard phrases refer to section 16. * 4 First-aid measures Description of first aid measures General information: Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident. After inhalation: If the patient feels unwell or is concerned, obtain medical advice. After skin contact: Immediately wash with soap, water and rinse thoroughly. If skin irritation continues, consult a doctor. After eye contact: Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor. After swallowing: Call for a doctor immediately. (Contd. on page 3)

Page 3/8 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Lysis Buffer Seek immediate medical advice. Information for doctor: Most important symptoms and effects, both acute and delayed None Indication of any immediate medical attention and special treatment needed No further relevant information available. (Contd. of page 2) 5 Fire-fighting measures Extinguishing media Suitable extinguishing agents: CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Special hazards arising from the substance or mixture None known Advice for firefighters No special advice. * 6 Accidental release measures Personal precautions, protective equipment and emergency procedures Remove persons from danger area. Wear protective clothing. Environmental precautions: Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and material for containment and cleaning up: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Dispose contaminated material as waste according to Section 13. Ensure adequate ventilation. Reference to other sections See Section 7 for information on safe handling See Section 13 for disposal information. 7 Handling and storage Handling Precautions for safe handling Keep receptacles tightly sealed. Ensure good ventilation/exhaustion at the workplace. Prevent formation of aerosols. Information about fire - and explosion protection: No special measures required. Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: Keep receptacle tightly sealed. Specific end use(s) No further relevant information available. * 8 Exposure controls/personal protection Additional information about design of technical facilities: No further data; see item 7. (Contd. on page 4)

Page 4/8 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Lysis Buffer (Contd. of page 3) Control parameters Ingredients with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists valid during the making were used as basis. Exposure controls Personal protective equipment General protective and hygienic measures Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin. Do not eat or drink while working. Clean skin thoroughly immediately after handling the product. Respiratory protection: In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device. Protection of hands: Protective gloves. Select the glove material considering penetration time, rate of diffusion and degradation time. The selected protective gloves must satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it or AS/NZS 2161. Material of gloves: The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Eye protection: Safety glasses Use equipment for eye protection tested and approved under government standard EN 166(EU) or AS/NZS 1336, 1137 and 1138. * 9 Physical and chemical properties Information on basic physical and chemical properties General Information Appearance: Form: Fluid Colour: Colourless Odour: Not determined Odour threshold: ph-value at 20 C: 6.4 Change in condition Melting point/melting range: undetermined Boiling point/boiling range: undetermined Flash point: > 100 C Flammability (solid, gaseous) Ignition temperature: Decomposition temperature: Not applicable. (Contd. on page 5)

Page 5/8 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Lysis Buffer Self-igniting: Danger of explosion: Explosion limits: Lower: Upper: Vapour pressure: Product is not selfigniting. Product does not present an explosion hazard. Density: Not determined Relative density Vapour density Evaporation rate Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: kinematic: Organic solvents: 0.0 % Water: 25.1 % Other information No further relevant information available. (Contd. of page 4) * 10 Stability and reactivity Reactivity No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Possibility of hazardous reactions Reacts with strong acids and oxidizing agents Conditions to avoid No further relevant information available. Incompatible materials: Oxidizing agents Hazardous decomposition products: No dangerous decomposition products known * 11 Toxicological information Information on toxicological effects Acute toxicity LD/LC50 values relevant for classification: 50-01-1 guanidinium chloride Oral LD50 475 mg/kg (Rat) Irritation of eyes acute 500 mg (Rabbit) Primary irritant effect: Skin corrosion/irritation Irritant to skin and mucous membranes. Serious eye damage/irritation Irritating effect. Respiratory or skin sensitisation No sensitising effects known. Additional toxicological information: The product shows the following dangers according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest version. Harmful (Contd. on page 6)

Page 6/8 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Lysis Buffer Irritant (Contd. of page 5) * 12 Ecological information Toxicity Aquatic toxicity: Not harmful to the aquatic environment Persistence and degradability: Not available Behaviour in environmental systems: Bioaccumulative potential Not known Mobility in soil No further relevant information available. Ecotoxical effects: Remark: Not available Additional ecological information: General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. Other adverse effects No further relevant information available. * 13 Disposal considerations Waste treatment methods Recommendation Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: Handling and Storage and Section 8: Exposure Control/Personal Protection for additional handling information and protection of employees. Uncleaned packaging: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agents: Water, if necessary together with cleansing agents. * 14 Transport information UN-Number ADR, ADN, IMDG, IATA UN proper shipping name ADR, ADN, IMDG, IATA Transport hazard class(es) ADR, ADN, IMDG, IATA Class Packing group ADR, IMDG, IATA Environmental hazards: Marine pollutant: Not hazardous for transportation None None None No (Contd. on page 7)

Page 7/8 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Lysis Buffer Special precautions for user Not applicable. Transport in bulk according to Annex II of Marpol and the IBC Code Not applicable. UN "Model Regulation": (Contd. of page 6) * 15 Regulatory information Safety, health and environmental regulations/legislation specific for the substance or mixture GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS). Signal word Warning Hazard-determining components of labelling: guanidinium chloride Hazard statements Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Precautionary statements Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Directive 2012/18/EU Named dangerous substances - ANNEX I None of the ingredients is listed. National regulations Waterhazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water. Chemical safety assessment: A Chemical Safety Assessment has not been carried out. 16 Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing SDS: Promega Corporation Safety Department 2800 Woods Hollow Road Madison, WI 53711 U.S.A. Abbreviations and acronyms: RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association EINECS: European Inventory of Existing Commercial Chemical Substances ELINCS: European List of Notified Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) (Contd. on page 8)

Page 8/8 Printing date 05.07.2016 Revision: 30.06.2016 Trade name: Lysis Buffer LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent PBT: Persistent, Bioaccumulative and Toxic vpvb: very Persistent and very Bioaccumulative Flam. Sol. 1: Flammable solids Category 1 Acute Tox. 4: Acute toxicity Category 4 Skin Irrit. 2: Skin corrosion/irritation Category 2 Eye Dam. 1: Serious eye damage/eye irritation Category 1 Eye Irrit. 2: Serious eye damage/eye irritation Category 2 Eye Irrit. 2A: Serious eye damage/eye irritation Category 2A STOT SE 2: Specific target organ toxicity (single exposure) Category 2 Aquatic Chronic 2: Hazardous to the aquatic environment - long-term aquatic hazard Category 2 * Data compared to the previous version altered. (Contd. of page 7)

Page 1/6 Printing date 05.07.2016 Revision: 27.06.2016 * 1 Identification Product identifier Trade name: Binding Buffer Article number: MC502 Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the preparation: Laboratory chemicals Details of the supplier of the safety data sheet Manufacturer/Supplier: Promega Corporation 2800 Woods Hollow Road Madison, WI 53711 U.S.A. 1-608-274-4330 1-800-356-9526 SDS author: Regulatory.Affairs@promega.com Further information obtainable from: Promega Pte Ltd 77 Science Park Drive 02-16 Cintech III Singapore Science Park I 118256 Singapore Tel: (65) 6513 3450 Fax: (65) 6773 5210 E-mail Address: sg_custserv@promega.com SDS author: regulatory_affairs@promega.com Emergency telephone number: For Chemical Emergency Spill, Leak, Fire, Exposure, or Accident Call CHEMTREC Day or Night. Within Singapore +800-101-2201 Within USA and Canada: 1-800-424-9300 Outside USA and Canada: +1 703-527-3887 (collect calls accepted). * 2 Hazards identification Classification of the substance or mixture The product is not classified according to the Globally Harmonised System (GHS). Label elements GHS label elements Hazard pictograms Signal word Hazard statements (Contd. on page 2)

Page 2/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: Binding Buffer Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. (Contd. of page 1) * 3 Composition/information on ingredients Chemical characterisation: Mixtures Description: The product is a mixture of the hazardous substances listed below along with unlisted nonhazardous substances. Components: Additional information: For the wording of the listed hazard phrases refer to section 16. * 4 First-aid measures Description of first aid measures General information: No special measures required. After inhalation: If the patient feels unwell or is concerned, obtain medical advice. After skin contact: Generally the product does not irritate the skin. After eye contact: Rinse opened eye for several minutes under running water. After swallowing: If the patient feels unwell or is concerned, obtain medical advice. Information for doctor: Most important symptoms and effects, both acute and delayed None Indication of any immediate medical attention and special treatment needed No further relevant information available. * 5 Fire-fighting measures Extinguishing media Suitable extinguishing agents: CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Special hazards arising from the substance or mixture None known Advice for firefighters No special advice. No special advice. Protective equipment: No special measures required. * 6 Accidental release measures Personal precautions, protective equipment and emergency procedures Not required. Environmental precautions: Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and material for containment and cleaning up: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Reference to other sections No dangerous substances are released. See Section 7 for information on safe handling (Contd. on page 3)

Page 3/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: Binding Buffer See Section 13 for disposal information. (Contd. of page 2) 7 Handling and storage Handling Precautions for safe handling No special measures required. Information about fire - and explosion protection: The product is not flammable Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. Specific end use(s) No further relevant information available. * 8 Exposure controls/personal protection Additional information about design of technical facilities: No further data; see item 7. Control parameters Ingredients with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists valid during the making were used as basis. Exposure controls Personal protective equipment General protective and hygienic measures The usual precautionary measures are to be adhered to when handling chemicals. Respiratory protection: Not required. Protection of hands: Not required. Material of gloves: The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Eye protection: Not required. * 9 Physical and chemical properties Information on basic physical and chemical properties General Information Appearance: Form: Fluid Colour: Colourless Odour: Not determined Odour threshold: ph-value at 20 C: 6.2 Change in condition Melting point/melting range: undetermined Boiling point/boiling range: 100 C (Contd. on page 4)

Page 4/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: Binding Buffer Flash point: Flammability (solid, gaseous) Ignition temperature: Decomposition temperature: Self-igniting: Danger of explosion: Explosion limits: Lower: Upper: Vapour pressure: Not applicable Not applicable. Product is not selfigniting. Product does not present an explosion hazard. Density: Not determined Relative density Vapour density Evaporation rate Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: kinematic: Organic solvents: 0.0 % Water: 80.4 % Solids content: 7.7 % Other information No further relevant information available. (Contd. of page 3) * 10 Stability and reactivity Reactivity No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Possibility of hazardous reactions No dangerous reactions known Conditions to avoid No further relevant information available. Incompatible materials: No further relevant information available. Hazardous decomposition products: No dangerous decomposition products known 11 Toxicological information Information on toxicological effects Acute toxicity LD/LC50 values relevant for classification: No data available Primary irritant effect: Skin corrosion/irritation No irritant effect. Serious eye damage/irritation Irritating effect. Respiratory or skin sensitisation No sensitising effects known. Additional toxicological information: The product is not subject to classification according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest version. (Contd. on page 5)

Page 5/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: Binding Buffer (Contd. of page 4) When used and handled according to specifications, the product does not have any harmful effects to our experience and the information provided to us. * 12 Ecological information Toxicity Aquatic toxicity: Not harmful to the aquatic environment Persistence and degradability: Not available Behaviour in environmental systems: Bioaccumulative potential Not known Mobility in soil No further relevant information available. Ecotoxical effects: Remark: Not available Additional ecological information: General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. Other adverse effects No further relevant information available. * 13 Disposal considerations Waste treatment methods Recommendation Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: Handling and Storage and Section 8: Exposure Control/Personal Protection for additional handling information and protection of employees. Uncleaned packaging: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agents: Water, if necessary together with cleansing agents. 14 Transport information UN-Number ADR, ADN, IMDG, IATA UN proper shipping name ADR, ADN, IMDG, IATA Transport hazard class(es) ADR, ADN, IMDG, IATA Class Packing group ADR, IMDG, IATA Environmental hazards: Marine pollutant: Not hazardous for transportation None None None No (Contd. on page 6)

Page 6/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: Binding Buffer Special precautions for user Not applicable. Transport in bulk according to Annex II of Marpol and the IBC Code Not applicable. UN "Model Regulation": (Contd. of page 5) * 15 Regulatory information Safety, health and environmental regulations/legislation specific for the substance or mixture GHS label elements Signal word Hazard statements Directive 2012/18/EU Named dangerous substances - ANNEX I None of the ingredients is listed. National regulations Waterhazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water. Chemical safety assessment: A Chemical Safety Assessment has not been carried out. 16 Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing SDS: Promega Corporation Safety Department 2800 Woods Hollow Road Madison, WI 53711 U.S.A. Abbreviations and acronyms: RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association EINECS: European Inventory of Existing Commercial Chemical Substances ELINCS: European List of Notified Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent PBT: Persistent, Bioaccumulative and Toxic vpvb: very Persistent and very Bioaccumulative * Data compared to the previous version altered.

Page 1/6 Printing date 05.07.2016 Revision: 27.06.2016 * 1 Identification Product identifier Trade name: MagaZorb Reagent Article number: MC503 Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the preparation: Laboratory chemicals Details of the supplier of the safety data sheet Manufacturer/Supplier: Promega Corporation 2800 Woods Hollow Road Madison, WI 53711 U.S.A. 1-608-274-4330 1-800-356-9526 SDS author: Regulatory.Affairs@promega.com Further information obtainable from: Promega Pte Ltd 77 Science Park Drive 02-16 Cintech III Singapore Science Park I 118256 Singapore Tel: (65) 6513 3450 Fax: (65) 6773 5210 E-mail Address: sg_custserv@promega.com SDS author: regulatory_affairs@promega.com Emergency telephone number: For Chemical Emergency Spill, Leak, Fire, Exposure, or Accident Call CHEMTREC Day or Night. Within Singapore +800-101-2201 Within USA and Canada: 1-800-424-9300 Outside USA and Canada: +1 703-527-3887 (collect calls accepted). * 2 Hazards identification Classification of the substance or mixture The product is not classified according to the Globally Harmonised System (GHS). Label elements GHS label elements Hazard pictograms Signal word Hazard statements (Contd. on page 2)

Page 2/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: MagaZorb Reagent Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. (Contd. of page 1) * 3 Composition/information on ingredients Chemical characterisation: Mixtures Description: The product is a mixture of the hazardous substances listed below along with unlisted nonhazardous substances. Components: 1309-37-1 diiron trioxide Skin Irrit. 2, H315; Eye Irrit. 2A, H319; STOT SE 3, H335 1.0-5.0% Additional information: For the wording of the listed hazard phrases refer to section 16. * 4 First-aid measures Description of first aid measures General information: No special measures required. After inhalation: If the patient feels unwell or is concerned, obtain medical advice. After skin contact: Generally the product does not irritate the skin. After eye contact: Rinse opened eye for several minutes under running water. After swallowing: If the patient feels unwell or is concerned, obtain medical advice. Information for doctor: Most important symptoms and effects, both acute and delayed None Indication of any immediate medical attention and special treatment needed No further relevant information available. * 5 Fire-fighting measures Extinguishing media Suitable extinguishing agents: CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Special hazards arising from the substance or mixture None known Advice for firefighters No special advice. No special advice. Protective equipment: No special measures required. 6 Accidental release measures Personal precautions, protective equipment and emergency procedures Not required. Environmental precautions: Dilute with plenty of water. Methods and material for containment and cleaning up: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Reference to other sections No dangerous substances are released. See Section 7 for information on safe handling (Contd. on page 3)

Page 3/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: MagaZorb Reagent See Section 13 for disposal information. (Contd. of page 2) 7 Handling and storage Handling Precautions for safe handling No special measures required. Information about fire - and explosion protection: The product is not flammable Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. Specific end use(s) No further relevant information available. * 8 Exposure controls/personal protection Additional information about design of technical facilities: No further data; see item 7. Control parameters Ingredients with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists valid during the making were used as basis. Exposure controls Personal protective equipment General protective and hygienic measures The usual precautionary measures are to be adhered to when handling chemicals. Respiratory protection: Not required. Protection of hands: Not required. Material of gloves: The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Eye protection: Not required. * 9 Physical and chemical properties Information on basic physical and chemical properties General Information Appearance: Form: Fluid Colour: Colourless Odour: Not determined Odour threshold: ph-value at 20 C: 7 Change in condition Melting point/melting range: undetermined Boiling point/boiling range: 100 C (Contd. on page 4)

Page 4/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: MagaZorb Reagent Flash point: Flammability (solid, gaseous) Ignition temperature: Decomposition temperature: Self-igniting: Danger of explosion: Explosion limits: Lower: Upper: Vapour pressure: Not applicable Not applicable. Product is not selfigniting. Product does not present an explosion hazard. Density: Not determined Relative density Vapour density Evaporation rate Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: kinematic: Organic solvents: 0.0 % Water: 95.0 % Other information No further relevant information available. (Contd. of page 3) * 10 Stability and reactivity Reactivity No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Possibility of hazardous reactions No dangerous reactions known Conditions to avoid No further relevant information available. Incompatible materials: No further relevant information available. Hazardous decomposition products: No dangerous decomposition products known 11 Toxicological information Information on toxicological effects Acute toxicity LD/LC50 values relevant for classification: No data available Primary irritant effect: Skin corrosion/irritation No irritant effect. Serious eye damage/irritation Irritating effect. Respiratory or skin sensitisation No sensitising effects known. Additional toxicological information: The product is not subject to classification according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest version. (Contd. on page 5)

Page 5/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: MagaZorb Reagent (Contd. of page 4) When used and handled according to specifications, the product does not have any harmful effects to our experience and the information provided to us. * 12 Ecological information Toxicity Aquatic toxicity: Not harmful to the aquatic environment Persistence and degradability: Not available Behaviour in environmental systems: Bioaccumulative potential Not known Mobility in soil No further relevant information available. Ecotoxical effects: Remark: Not available Additional ecological information: General notes: Generally not hazardous for water. Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. Other adverse effects No further relevant information available. * 13 Disposal considerations Waste treatment methods Recommendation Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: Handling and Storage and Section 8: Exposure Control/Personal Protection for additional handling information and protection of employees. Uncleaned packaging: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agents: Water, if necessary together with cleansing agents. 14 Transport information UN-Number ADR, ADN, IMDG, IATA UN proper shipping name ADR, ADN, IMDG, IATA Transport hazard class(es) ADR, ADN, IMDG, IATA Class Packing group ADR, IMDG, IATA Environmental hazards: Marine pollutant: Special precautions for user Not hazardous for transportation None None None No Not applicable. (Contd. on page 6)

Page 6/6 Printing date 05.07.2016 Revision: 27.06.2016 Trade name: MagaZorb Reagent Transport in bulk according to Annex II of Marpol and the IBC Code Not applicable. (Contd. of page 5) UN "Model Regulation": * 15 Regulatory information Safety, health and environmental regulations/legislation specific for the substance or mixture GHS label elements Signal word Hazard statements Directive 2012/18/EU Named dangerous substances - ANNEX I None of the ingredients is listed. National regulations Waterhazard class: Generally not hazardous for water. Chemical safety assessment: A Chemical Safety Assessment has not been carried out. 16 Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing SDS: Promega Corporation Safety Department 2800 Woods Hollow Road Madison, WI 53711 U.S.A. Abbreviations and acronyms: RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association EINECS: European Inventory of Existing Commercial Chemical Substances ELINCS: European List of Notified Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent PBT: Persistent, Bioaccumulative and Toxic vpvb: very Persistent and very Bioaccumulative Skin Irrit. 2: Skin corrosion/irritation Category 2 Eye Irrit. 2A: Serious eye damage/eye irritation Category 2A STOT SE 3: Specific target organ toxicity (single exposure) Category 3 * Data compared to the previous version altered.

Page 1/6 Printing date 05.07.2016 Revision: 03.06.2016 * 1 Identification Product identifier Trade name: Wash Buffer Article number: MC504 Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the preparation: Laboratory chemicals Details of the supplier of the safety data sheet Manufacturer/Supplier: Promega Corporation 2800 Woods Hollow Road Madison, WI 53711 U.S.A. 1-608-274-4330 1-800-356-9526 SDS author: Regulatory.Affairs@promega.com Further information obtainable from: Promega Pte Ltd 77 Science Park Drive 02-16 Cintech III Singapore Science Park I 118256 Singapore Tel: (65) 6513 3450 Fax: (65) 6773 5210 E-mail Address: sg_custserv@promega.com SDS author: regulatory_affairs@promega.com Emergency telephone number: For Chemical Emergency Spill, Leak, Fire, Exposure, or Accident Call CHEMTREC Day or Night. Within Singapore +800-101-2201 Within USA and Canada: 1-800-424-9300 Outside USA and Canada: +1 703-527-3887 (collect calls accepted). * 2 Hazards identification Classification of the substance or mixture The product is not classified according to the Globally Harmonised System (GHS). Label elements GHS label elements Hazard pictograms Signal word Hazard statements (Contd. on page 2)

Page 2/6 Printing date 05.07.2016 Revision: 03.06.2016 Trade name: Wash Buffer Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. (Contd. of page 1) * 3 Composition/information on ingredients Chemical characterisation: Mixtures Description: The product is a mixture of the hazardous substances listed below along with unlisted nonhazardous substances. Components: Additional information: For the wording of the listed hazard phrases refer to section 16. * 4 First-aid measures Description of first aid measures General information: No special measures required. After inhalation: If the patient feels unwell or is concerned, obtain medical advice. After skin contact: Generally the product does not irritate the skin. After eye contact: Rinse opened eye for several minutes under running water. After swallowing: If the patient feels unwell or is concerned, obtain medical advice. Information for doctor: Most important symptoms and effects, both acute and delayed None Indication of any immediate medical attention and special treatment needed No further relevant information available. * 5 Fire-fighting measures Extinguishing media Suitable extinguishing agents: CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Special hazards arising from the substance or mixture None known Advice for firefighters No special advice. No special advice. Protective equipment: No special measures required. * 6 Accidental release measures Personal precautions, protective equipment and emergency procedures Not required. Environmental precautions: Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and material for containment and cleaning up: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Reference to other sections No dangerous substances are released. See Section 7 for information on safe handling (Contd. on page 3)

Page 3/6 Printing date 05.07.2016 Revision: 03.06.2016 Trade name: Wash Buffer See Section 13 for disposal information. (Contd. of page 2) 7 Handling and storage Handling Precautions for safe handling No special measures required. Information about fire - and explosion protection: The product is not flammable Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. Specific end use(s) No further relevant information available. * 8 Exposure controls/personal protection Additional information about design of technical facilities: No further data; see item 7. Control parameters Ingredients with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists valid during the making were used as basis. Exposure controls Personal protective equipment General protective and hygienic measures The usual precautionary measures are to be adhered to when handling chemicals. Respiratory protection: Not required. Protection of hands: Not required. Material of gloves: The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Eye protection: Not required. * 9 Physical and chemical properties Information on basic physical and chemical properties General Information Appearance: Form: Fluid Colour: Colourless Odour: Not determined Odour threshold: ph-value at 20 C: 6.2 Change in condition Melting point/melting range: undetermined Boiling point/boiling range: 100 C (Contd. on page 4)

Page 4/6 Printing date 05.07.2016 Revision: 03.06.2016 Trade name: Wash Buffer Flash point: Flammability (solid, gaseous) Ignition temperature: Decomposition temperature: Self-igniting: Danger of explosion: Explosion limits: Lower: Upper: Vapour pressure: Not applicable Not applicable. Product is not selfigniting. Product does not present an explosion hazard. Density: Not determined Relative density Vapour density Evaporation rate Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: kinematic: Organic solvents: 0.0 % Water: 86.4 % Solids content: 7.7 % Other information No further relevant information available. (Contd. of page 3) * 10 Stability and reactivity Reactivity No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Possibility of hazardous reactions No dangerous reactions known Conditions to avoid No further relevant information available. Incompatible materials: No further relevant information available. Hazardous decomposition products: No dangerous decomposition products known * 11 Toxicological information Information on toxicological effects Acute toxicity LD/LC50 values relevant for classification: No data available Primary irritant effect: Skin corrosion/irritation No irritant effect. Serious eye damage/irritation Irritating effect. Respiratory or skin sensitisation No sensitising effects known. Additional toxicological information: The product is not subject to classification according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest version. (Contd. on page 5)

Page 5/6 Printing date 05.07.2016 Revision: 03.06.2016 Trade name: Wash Buffer (Contd. of page 4) When used and handled according to specifications, the product does not have any harmful effects to our experience and the information provided to us. * 12 Ecological information Toxicity Aquatic toxicity: Not harmful to the aquatic environment Persistence and degradability: Not available Behaviour in environmental systems: Bioaccumulative potential Not known Mobility in soil No further relevant information available. Ecotoxical effects: Remark: Not available Additional ecological information: General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. Other adverse effects No further relevant information available. * 13 Disposal considerations Waste treatment methods Recommendation Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: Handling and Storage and Section 8: Exposure Control/Personal Protection for additional handling information and protection of employees. Uncleaned packaging: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agents: Water, if necessary together with cleansing agents. * 14 Transport information UN-Number ADR, ADN, IMDG, IATA UN proper shipping name ADR, ADN, IMDG, IATA Transport hazard class(es) ADR, ADN, IMDG, IATA Class Packing group ADR, IMDG, IATA Environmental hazards: Marine pollutant: Not hazardous for transportation None None None No (Contd. on page 6)

Page 6/6 Printing date 05.07.2016 Revision: 03.06.2016 Trade name: Wash Buffer Special precautions for user Not applicable. Transport in bulk according to Annex II of Marpol and the IBC Code Not applicable. UN "Model Regulation": (Contd. of page 5) * 15 Regulatory information Safety, health and environmental regulations/legislation specific for the substance or mixture GHS label elements Signal word Hazard statements Directive 2012/18/EU Named dangerous substances - ANNEX I None of the ingredients is listed. National regulations Waterhazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water. Chemical safety assessment: A Chemical Safety Assessment has not been carried out. 16 Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing SDS: Promega Corporation Safety Department 2800 Woods Hollow Road Madison, WI 53711 U.S.A. Abbreviations and acronyms: RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the International Transport of Dangerous Goods by Rail) ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association EINECS: European Inventory of Existing Commercial Chemical Substances ELINCS: European List of Notified Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent PBT: Persistent, Bioaccumulative and Toxic vpvb: very Persistent and very Bioaccumulative * Data compared to the previous version altered.

Page 1/6 Printing date 05.07.2016 Revision: 27.06.2016 * 1 Identification Product identifier Trade name: Elution Buffer Article number: MC505 Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the preparation: Laboratory chemicals Details of the supplier of the safety data sheet Manufacturer/Supplier: Promega Corporation 2800 Woods Hollow Road Madison, WI 53711 U.S.A. 1-608-274-4330 1-800-356-9526 SDS author: Regulatory.Affairs@promega.com Further information obtainable from: Promega Pte Ltd 77 Science Park Drive 02-16 Cintech III Singapore Science Park I 118256 Singapore Tel: (65) 6513 3450 Fax: (65) 6773 5210 E-mail Address: sg_custserv@promega.com SDS author: regulatory_affairs@promega.com Emergency telephone number: For Chemical Emergency Spill, Leak, Fire, Exposure, or Accident Call CHEMTREC Day or Night. Within Singapore +800-101-2201 Within USA and Canada: 1-800-424-9300 Outside USA and Canada: +1 703-527-3887 (collect calls accepted). * 2 Hazards identification Classification of the substance or mixture The product is not classified according to the Globally Harmonised System (GHS). Label elements GHS label elements Hazard pictograms Signal word Hazard statements (Contd. on page 2)