GCE AS and A Level. Human Biology. AS exams 2009 onwards A2 exams 2010 onwards. Unit 5: Specimen mark scheme. Version 1.0

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GCE AS and A Level Human Biology AS exams 2009 onwards A2 exams 2010 onwards Unit 5: Specimen mark scheme Version 1.0

Version 1.0: 0307 abc General Certificate of Education Human Biology 2405 HBIO5 The air we breathe, the water we drink, the food we eat Mark Scheme Specimen Paper

Mark schemes are prepared by the Principal Examiner and considered, together with the relevant questions, by a panel of subject teachers. This mark scheme includes any amendments made at the standardisation meeting attended by all examiners and is the scheme which was used by them in this examination. The standardisation meeting ensures that the mark scheme covers the candidates responses to questions and that every examiner understands and applies it in the same correct way. As preparation for the standardisation meeting each examiner analyses a number of candidates scripts: alternative answers not already covered by the mark scheme are discussed at the meeting and legislated for. If, after this meeting, examiners encounter unusual answers which have not been discussed at the meeting they are required to refer these to the Principal Examiner. It must be stressed that a mark scheme is a working document, in many cases further developed and expanded on the basis of candidates reactions to a particular paper. Assumptions about future mark schemes on the basis of one year s document should be avoided; whilst the guiding principles of assessment remain constant, details will change, depending on the content of a particular examination paper. Further copies of this Mark Scheme are available to download from the AQA Website: www.aqa.org.uk Copyright 2007 AQA and its licensors. All rights reserved. COPYRIGHT AQA retains the copyright on all its publications. However, registered centres for AQA are permitted to copy material from this booklet for their own internal use, with the following important exception: AQA cannot give permission to centres to photocopy any material that is acknowledged to a third party even for internal use within the centre. Set and published by the Assessment and Qualifications Alliance. The Assessment and Qualifications Alliance (AQA) is a company limited by guarantee registered in England and Wales (company number 3644723) and a registered charity (registered charity number 1073334). Registered address: AQA, Devas Street, Manchester M15 6EX Dr Michael Cresswell Director General

Question 1 Polluter pays the direct costs of pollution; And indirect costs; 2 Waste materials should be, Re-used; Recycled and used as raw material; Used as a substitute for non-renewable energy sources; Only sent to landfill if all above not possible; Total 5 3 max Question 2 (Cryptosporidium) oocyst; From (contaminating) faeces/slurry; 2 (i) Suitable advantage, explained;; Saves electricity; So less carbon dioxide to atmosphere; 2 (ii) Suitable disadvantage, explained;; Some people still go into the sea (in winter); Get infected with (coliform) bacteria causing illness; 2 Total 6 Question 3 Two changes described, Fewer species; Move north/get to Britain; Fewer in south/around Mediterranean; 2 max Factor changing; with explanation; Warmer in north; So plants able to survive winter; 2 (c) Use of grid; Random numbers for coordinates; Count number of species/record species in each quadrat; Results from many quadrats; Total 7 3 max 3

Question 4 Succession leads to changes in communities with time; Each community changes abiotic factors; Shrubs/trees outcompete orchids/change abiotic factors, so orchids cannot survive; 3 (i) PFA needed for orchid growth; 1 (ii) In other experiment, two factors changed/woodland and soil removed; Could have been competition with trees that prevented orchids growing; 2 Total 6 Question 5 Reduces combustion of fossil fuels; Reduces carbon dioxide release; (Biofuel plants) absorb carbon dioxide; In photosynthesis; Two suitable reasons;; For example; Larger the total area of agricultural land different, the less percentage to get same effect; Fewer the number of vehicles, the less land needed to get (10%) reduction; Different climates lead to different rates of growth/production of biofuel crops; 3 max 2 max Total 5 Question 6 Reason and explanation;; Reduces secretion of protein; Suitable role of protein; And consequence of reduced secretion; (Including) enzymes for extracellular digestion; So bacterium unable to absorb nutrients/named e.g.s; 3 S. epidermis feeds on the skin; Competes with other bacteria; Uses substance to prevent competitors growing; 3 4

(c) Suitable suggestion; with explanation; Substance binds to receptor on membrane of S. aureus; This is a protein required for transport across membrane (of secreted protein); Higher concentration of substance less effective, because all/most receptors full; 2 max Total 8 Question 7 (c) B higher concentration of triclosan needed to kill them; More triclosan needed where soap also present; 2 To separate effects of soap and triclosan; Could have been soap that killed bacteria; 2 Suitable procedure; with explanation; Bacteria exposed to solutions for two hours; Nobody washes hands for that long; No solution of soap on its own; Soap might be effective on its own; 2 max (d) Suitable suggestion, explained;; Question 8 Mutation; Leading to production of enzyme/protein giving resistance to triclosan; Horizontal transmission; Transfer of plasmid/genes from another bacterium; 2 Total 8 Populations; Of different species of bacteria; Living in the same place; 3 (Bacteria) in A and B survive stomach, C do not; But C may survive if taken in capsule; Result for A suggest capsule broken down; But A could be different capsule to C; Solution may not have same effect as stomach contents; Total 6 3 Max 5

Question 9 Antigen; Producing an abnormal immune response; 2 Allergen still present after cooking/exposure to high temperature; Something in the peanut activated by heating; Albumin is major allergen; Not digested/hydrolysed by trypsin; So allergen remains active in small intestine; Total 6 4 max Question 10 Reason, with explanation;; Knotweed outcompetes native plants; Removing food for animals/animals cannot eat knotweed; 2 (i) 108 000;; 2 36 000; (For 1 mark) (ii) First treatment leaves knotweed to re-grow; Next treatments remove 95% of any remainder/prevents regrowth; 2 (c) (i) Two suitable suggestions, with explanations;;;; Lack of amino acids prevents some proteins being made; These essential enzymes/structural proteins; Shikimate is toxic; Kills cells/blocks metabolic pathway; Lot of ATP from respiration/photosynthesis used, so not enough for growth; Lot of reduced NADP/ATP taken from photosynthesis, so reduces light independent reaction/sugar formation; 4 max (ii) Similar shape to PEP; Competes for/binds to active site of enzyme; 2 Total 12 6

General Principles for marking the Essay: Four skill areas will be marked: scientific content, breadth of knowledge, relevance and quality of language. The following descriptors will form a basis for marking. Scientific Content (maximum 16 marks) Marks for Scientific Content will be awarded for any suitable material. The following indicate areas of the Specification which contain content that might be relevant to the titles. Module 1 1.1 We are what we eat 1.2 Enzymes 1.3 Cystic fibrosis 1.5 How the body fights disease Module 2 2.1 The information of life 2.3 Adaptations to a way of life 2.5 We have changed and are changing our environment Module 4 4.2 Growing up, growing old and passing on your genes 4.3 The management structure of cells 4.4 New genes for old 4.5 Drugs can affect how we perceive the world around us 4.6 Fight or flight Module 5 5.2 Humans health can be affected when they change their environment Module 1 1.4 Microorganisms use us for food, shelter and their reproduction Module 2 2.4 Where we fit in the world and how we came to be here 2.5 We have changed and are changing our environment Module 4 4.4 New genes for old Module 5 5.1 People change communities 5.3 Human activities can damage ecosystems and create new ones 5.4 Plants can reduce the impact of the use of fossil fuels on climate change 5.5 People and their microorganisms 5.6 Human impacts on evolution 7

Category Mark Descriptor 16 Good 14 Most of the material reflects a comprehensive understanding of the principles involved and a knowledge of factual detail fully in keeping with a programme of A-level study. Some material, however, may be a little superficial. Material is accurate and free from fundamental errors but there may be minor errors which detract from the overall accuracy. 12 10 Average 8 6 4 Poor 2 0 Some of the content is of an appropriate depth, reflecting the depth of treatment expected from a programme of A-level study. Generally accurate with few, if any, fundamental errors. Shows a sound understanding of the key principles involved. Material presented is largely superficial and fails to reflect the depth of treatment expected from a programme of A-level study. If greater depth of knowledge is demonstrated, then there are many fundamental errors. 8

Breadth of Knowledge (maximum 3 marks) Mark Descriptor 3 A balanced account making reference to most areas that might realistically be covered on an A-level course of study. 2 A number of aspects covered but a lack of balance. Some topics essential to an understanding at this level not covered. 1 Unbalanced account with all or almost all material based on a single aspect. 0 Material entirely irrelevant or too limited in quantity to judge. Relevance (maximum 3 marks) Mark Descriptor 3 All material presented is clearly relevant to the title. Allowance should be made for judicious use of introductory material. 2 Material generally selected in support of title but some of the main content of the essay is of only marginal relevance. 1 Some attempt made to relate material to the title but considerable amounts largely irrelevant. 0 Material entirely irrelevant or too limited in quantity to judge. Quality of language (maximum 3 marks) Mark Descriptor 3 Material is logically presented in clear, scientific English. Technical terminology has been used effectively and accurately throughout. 2 Account is logical and generally presented in clear, scientific English. Technical terminology has been used effectively and is usually accurate. 1 The essay is generally poorly constructed and often fails to use an appropriate scientific style and terminology to express ideas. 0 Material entirely irrelevant or too limited in quantity to judge. Total 25 9

Guidelines for marking the essay Introduction The essay is intended for the assessment of AO4 (Synthesis of knowledge, understanding and skills) and Quality of Written Communication (Sections 6.4 and 6.5 in the specification). Examiners are looking for evidence of knowledge and understanding at a depth appropriate to A level selection of relevant knowledge and understanding from different areas of the specification coverage of the main concepts and principles that might be reasonably be expected in relation to the essay title connection of concepts, principles and other information from different areas in response to the essay title construction of an account that forms a coherent response clear and logical expression, using accurate specialist vocabulary appropriate to A level Assessing Scientific Content Maximum 16 marks. Descriptors are divided into 3 categories: Good (16, 14, 12), Average (10, 8, 6) and Poor (4, 2, 0). Only even scores can be awarded, i.e. not 15, 13, etc. Examiners need first to decide into which category an essay comes. A good essay includes a level of detail that could be expected from a comprehensive knowledge and understanding of relevant parts of the specification maintains appropriate depth and accuracy throughout avoids fundamental errors covers a majority of the main areas that might be expected from the essay title (These areas will be indicated in the mark scheme). (Occasionally a candidate may tackle an essay in an original or unconventional way. Such essays may be biased in a particular way, but where a high level of understanding is shown a high mark may be justified.) demonstrates clearly the links between principles and concepts from different areas. Note that it is not expected that an essay must be 'perfect' or exceptionally long in order to gain maximum marks, bearing in mind the limitations on time and the pressure arising from exam conditions. An average essay should include material that might be expected of C/D/E grade candidates is likely to have less detail and be more patchy in the depth to which areas are covered, and to omit several relevant areas is likely to include some errors and misunderstandings, but should have few fundamental errors is likely to include mainly more superficial and less explicit connections 10

A poor essay is largely below the standard expected of a grade E candidate shows limited knowledge and understanding of the topic is likely to cover only a limited number of relevant areas and may be relatively short is likely to provide superficial treatment of connections includes several errors, including some major ones Having decided on the basic category, examiners may award the median mark, or the ones above or below the median according to whether the candidate exceeds the requirements or does not quite meet them. Marking the essay In marking scientific content, letters in the margin show each key area covered; these are used to assess the breadth of criteria. A single tick is used to indicate accurate coverage of each significant area, and a double tick to emphasise good depth of content. Errors are indicated with a cross. A squiggly line in the margin is used to highlight irrelevance and Q to highlight poor use of terminology, unclear grammar and inappropriate style. Specific guidance for assessing Scientific Content and Breadth of Knowledge in Essays The following provides guidance about topics which might be included in the essays. It is not an exclusive list; the assessment of scientific content does not place restrictions on topics that candidates might refer to, provided they are relevant; at an appropriate depth for A level and accurate. It is not expected that candidates would refer to all, or even most, of the topics to gain a top mark; the list represents the variety of approaches commonly encountered in the assessment to the essays. In both essays, topics either from the option modules or beyond the scope of the specification should also given credit where appropriate. 11