SAFETY DATA SHEET 1. IDENTIFICATION OF SUBSTANCE/ MIXTURE AND THE COMPANY/ UNDERTAKING PRODUCT: 080389 Sodium Hydroxide 50%, 500 ml Thermo Fisher Scientific Emergency Phone: 1-800-424-9300 (CHEMTREC) +1-703-527-3887 (INTERNATIONAL) Information Phone: Sunnyvale, California Date Revised: 04/02/2015 For laboratory use. 2. HAZARD(S) IDENTIFICATION Classification of the Substance or Mixture: GHS05 Corrosive Signal Word: Danger Hazard Statements: H314 Causes severe skin burns and eye damage H303 Maybe harmful if swallowed H333 Maybe harmful if inhaled H335 May cause respiratory irritation H290 May be corrosive to metals Potential Health Effects: Eyes: Causes eye damage. Skin: Causes severe skin burns. Inhalation: Causes respiratory irritation. Ingestion: Harmful if swallowed. Precautionary Statements: All Classifications meet the CLP/GHS requirements. P234 Keep only in original container. P233 Keep container tightly closed P260 Do not breathe dust/fume/gas/mist/vapours/spray P312 Call a POISON CENTER or doctor/physician if you feel unwell P406 Store in corrosive resistant/ container with a resistant inner liner. SDS 088133, Rev. 04 Page 1 of 7
CLP/GHS CLASSIFICATION (1272/2008): METAL CORROSIVE: (Category 1B) SKIN CORROSIVE: (Category 1B) EU CLASSIFICATION (67/548/EEC): EUH210 Safety data sheet available on request. EUH071 Corrosive to the respiratory tract. EUH401 To avoid risks to human health and the environment, comply with the instructions for use. GHS Label Elements: Corrosive Danger! Contains Sodium Hydroxide 3. COMPOSITION/INFORMATION ON INGREDIENTS HAZARDOUS COMPONENTS Water Sodium Hydroxide PERCENT (W/V%) 50.0 50.0 CAS NO. 7732-18-5 1310-73-2 EINECS NO. 231-791-2 215-185-5 4. FIRST AID MEASURES GENERAL: EYES: SKIN: INHALATION: INGESTION: Remove contaminated clothing, wash thoroughly before reuse. Flush with water for at least 15 minutes occasionally raising upper and lower eyelids. Consult a physician. Remove contaminated clothing and flush skin with water thoroughly. Consult a physician. Move to fresh air If large amounts are swallowed, get medical help immediately. If patient is conscious, give large quantities of water. Consult a physician. DO NOT INDUCE VOMITING! 5. FIRE FIGHTING MEASURES Hazardous Combustion Products: Extinguishing Media: Substance is non-flammable; use agent most appropriate to extinguish surrounding fire. Special Protective Actions For Fire Fighters: NFPA: Health: 3 Flammability: 0 Instability: 1 Physical Hazards: N/A SDS 088133, Rev. 04 Page 2 of 7
6. ACCIDENTAL RELEASE MEASURES PERSONAL: ENVIRONMENT: METHODS FOR CONTAINMENT AND CLEAN UP: Use personal protective equipment. Evacuate personnel to safe areas. Keep people away from and upwind of leak/spill. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Should not be released into the environment. Soak up with inert sorbent material. Keep in suitable, closed containers for disposal. 7. HANDLING AND STORAGE HANDLING: STORAGE: Use only under a chemical fume hood. Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Keep containers tightly closed in a dry, cool and well ventilated place. Corrosives area. 8. EXPOSURE CONTROL/PERSONAL PROTECTION Routes of Entry: Health Hazards: INHALATION: SKIN: INGESTION: ACUTE: CHRONIC: Ventilation: LOCAL EXHAUST: MECHANICAL (GENERAL): SPECIAL: OTHER: Protective Clothing Or Equipment: GLOVES: EYE PROTECTION: RESPIRATORY: OTHER: Yes Yes Yes May cause burns to skin, eyes and mucous membranes. Good laboratory ventilation is acceptable. Use in hoods if possible Disposable nitrile gloves Safety glasses or goggles Lab coats 9. PHYSICAL AND CHEMICAL PROPERTIES APPEARANCE: Clear ODOR: None ph: 12.0 Alkaline MOLECULAR WEIGHT: 96.106 MELTING POINT: 5-10.6 degrees C / 41-51.1 degrees F SDS 088133, Rev. 04 Page 3 of 7
BOILING POINT: AUTOIGNITION TEMPERATURE: FLASH POINT: LOWER EXPLOSION LIMIT: UPPER EXPLOSION LIMIT: SPECIFIC GRAVITY: SOLUBILITY: FREEZING POINT: EVAPORATION RATE: FLAMMABILITY: VAPOR PRESSURE: VAPOR DENSITY: DECOMPOSITION TEMPERATURE: VISCOSITY: SOLUBILITIES: PARTITION COEFFICIENT: 141.7 degrees C / 287.1 degrees F 1.530 @ 15.6 degrees C Soluble in water 10. STABILITY & REACTIVITY STABILITY/CONDITIONS TO AVOID: CONDITIONS TO AVOID: INCOMPATIBILITY (MATERIALS TO AVOID): HAZARDOUS DECOMPOSITION OR BY-PRODUCTS: BY-PRODUCTS: HAZARDOUS REACTIONS: Stable under normal conditions. May react with metals and lead to the formation of flammable hydrogen gas. Incompatible products. Excess heat. Acids, metals Carbon donoxide (CO), Carbon dioxide (CO2), Sodium oxides Does not occur None under normal processing 11. TOXICOLOGY INFORMATION PRODUCT TOXICOLOGY INFORMATION: Acute toxicity: May cause burns to skin, eyes or mucous membranes. Skin corrosion/irritation: Corrosive to skin Serious eye damage/irritation: May cause serious eye damage. Respiratory or skin sensitization: In case of contact, wash skin with copious amounts of water. Flush eyes with copious amounts of water for at least 15 minutes. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Germ cell mutagenicity: Carcinogenicity: SDS 088133, Rev. 04 Page 4 of 7
Reproductive toxicity: STOT-single exposure: STOT-repeated exposure: Aspiration hazard: Likely routes of exposure: OSHA PEL: NTP: IARC Monographs: ACGIH TLV TWA: Ingestion, skin HAZARDOUS COMPONENT TOXICOLOGY INFORMATION: HAZARDOUS COMPONENTS: RTECS #: OSHA PEL: ACGIH TLV: TOXICITY DATA: 12. ECOLOGICAL INFORMATION Sodium Hydroxide WB4900000 2mg/m3 2mg/m3 ORL-RAT LDLo: 200 mg/kg IPR-RAT LDLo: 50 mg/kg No information is found on environmental toxicity for this solution 13. DISPOSAL CONSIDERATIONS Dispose of according to local, state and federal regulations. 14. TRANSPORT INFORMATION USDOT CLASSIFICATION: IATA CLASSIFICATION: IMO/IMDG CLASSIFICATION: PROPER SHIPPING NAME: CLASS OR DIVISION 8 HAZARD LABEL(S) PACKAGING GROUP Sodium hydroxide solution Corrosive PROPER SHIPPING NAME: CLASS OR DIVISION: 8 HAZARD LABEL(S): PACKAGING GROUP: SDS 088133, Rev. 04 Page 5 of 7 II Sodium hydroxide solution Corrosive PROPER SHIPPING NAME: CLASS OR DIVISION: 8 II Sodium hydroxide solution
ADR CLASSIFICATION: Not a marine pollutant. HAZARD LABEL(S): Corrosive PACKAGING GROUP: II PROPER SHIPPING NAME: Sodium hydroxide solution CLASS OR DIVISION: 8 HAZARD LABEL(S): Corrosive PACKAGING GROUP: II Sudden Release of Pressure Hazard: No Reactive Hazard: Yes 15. REGULATORY INFORMATION U.S. Federal Regulations TSCA 12(b): Not applicable SARA 313: Not applicable SARA 311/312 Hazardous Categorization Acute Health Hazard: Yes Chronic Health Hazard: Yes Fire Hazard: No Sudden Release of Pressure Hazard: No Reactive Hazard: Yes Clean Water Act Component CWA Hazardous Substances CWA Reportable Quantities CWA Toxic Pollutants CWA Priority Pollutants Sodium hydroxide 1000 lb RQ Clean Air Act Not applicable OSHA Not applicable CERCLA This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) Component Hazardous Substances RQs CERCLA EHS RQs Sodium hydroxide 1000 lb. - - SDS 088133, Rev. 04 Page 6 of 7
California Proposition 65 This product does not contain any Proposition 65 chemicals. U.S. Department of Transportation Reportable Quantity (RQ): Yes DOT Marine Pollutant: No DOT Severe Marine Pollutant: No U.S. Department of Homeland Security This product does not contain any DHS chemicals. Other International Regulations Mexico Grade: No information available Canada: This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the SDS contains all the information required by the CPR. WHMIS Hazard Class Corrosive material 16. OTHER INFORMATION PRODUCT RISK STATEMENTS: R20/22 Harmful by inhalation/ Harmful if swallowed R36 Irratating to eyes PRODUCT SAFETY STATEMENTS: S20 When using do not eat or drink. S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 Wear suitable protective clothing/ gloves/ eye and face protection. S45 In case of accident or if you feel unwell seek medical advice immediately This Safety Data Sheet has been prepared in accordance with the REACH regulation in the EU and the Globally Harmonized System for the Classification and Labeling of Chemicals (GHS). It complies with the requirements of the Canadian Controlled Products Regulations and US 29CFR 1910.1200. To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries makes any warranty of Merchantability or any other warranty, expressed or implied, which respect to such information, and we assume no liability resulting from its use. In no event shall Thermo Fisher Scientific be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages resulting from use of or reliance upon this information. SDS 088133, Rev. 04 Page 7 of 7