PROJECT REPORT FOR MANUFACTURING THINQ PHARMA CRO LTD PITHAMPUR -3 BADGAON MADHYA PRADESH

PROJECT REPORT FOR MANUFACTURING THINQ PHARMA CRO LTD PITHAMPUR -3 BADGAON MADHYA PRADESH

CONTENTS 1. INTRODUCTION 2. GENERAL SECTION 3. PARTICULARS OF PROJECT 4. COST OF PROJECT AND MEANS OF FINANCING 5. PROFITABILITY STATEMENT

Background & Promoters THINQ represents the creative amalgamation of Technology, Health, Innovation, Novelty and Quest. Technology that meets state-of-the-art precision; Health, our first priority; Innovation that combines intelligence and passion; Novelty so we may stand head and shoulders above the rest and the Quest to make a real difference in the lives we touch. THINQ PHARMA CRO LTD ( THINQ ) was incorporated in November 2006 by Mr Shekhar Nadkarni at Thane close to Mumbai with the objective of development, manufacturing and marketing of pharmaceutical products. Mr. Shekhar Nadkarni who is a promoter and founder of THINQ Pharma-CRO is widely known personality in the CRAMs industry due to his 30+ years of experience. He was one of the pioneers to start off with the CRAMs business in India. Being in business for long time with all major manufacturing companies; he has an easy access to these units for scale up & commercial projects with better terms for costing, quality and timeline. Products API (Active Pharma Ingredients) Products APIs are used to make the finished pharmaceutical formulations which are consumed. Finished formulations are in the various dosage forms such as tablets, capsules, semi solid, gels, injectibles etc. Our API business is committed to deliver high quality products to the market. We have a dedicated R&D setup for active ingredients with quality control laboratories enabling us to cater to diverse markets. Currently our products are contract manufactured at various facilities. The manufacturer is chosen for any product depending upon the requirements of the product. We currently have manufacturing facilities with whom we have excellent relations and long term arrangements. The manufacturing facilities chosen comply with regulatory requirements. Advanced Intermediate Products The Advanced Intermediates products are intermediate product which are a few steps away from the final API. We have a range of products that combines business operations in the fields of basic and fine chemicals. We manufacture advance and bulk intermediates on multi ton level under Exclusive and Confidentiality Agreements with our associate Indian manufacturers having cgmp compliance. Natural Products

In addition to chemistry based products we have also forayed into natural products market. Our manufacturing is supported by R& D and clinical studies result in the development of safe & efficacious products. These products would be delivered to the market with consistent quality. Market- Market potential & Competitors Currently we market our products in India, LATAM, SEA and the non- regulatory markets. Technology & Manufacturing : We have our in house R& D team and also a production team comprising 3 Production managers, 2 chemical engineers which enables us to scale up the technology developed in the laboratory to the factory. Innovation Innovation has been corner stone of Thinq s progress. There is a constant endeavour to develop products and processes.

SECTION II- General Information General Information 1.1. Name of Industrial Concern THINQ PHARMA CRO LTD 1.2. Constitution Public Unlisted Company Copy of Memorandum and Articles of Association enclosed 1.3. Date of Incorporation 10.11.2006 1.4. Date of Commencement of Business 10.11.2006 1.5 Location a. Registered Office D-3, Daginawala Mansion, Mahim, Mumbai 4000016 b. Controlling Head Office A/30, Road No.10, MIDC, Wagle Estate, Thane West c. Project Pithampur, Madhya Pradesh 1.6 Nature of Industry and Products 1.7 Company Results (2 years) Details 2014-15 2013-14 Turnover 1205.96 957.77 Gross Profit 70.77 64.57 Gross Profit to Turnover 0.06 0.07 Depreciation 76.28 64.95 Dividend per share in Rs EPS in Rs. 98.21 87.38 1.8 Board of Directors Name DIN Chandrashekhar Nadkarni 00780294 Shibani Nadkarni 01256853 Ravindra Gulgule 03629811 Rohit Gulgule 01256887

1.9 List of key executives Name Chandrashekhar Nadkarni Shibani Nadkarni Ravindra Gulgule KRN Moorthy Position Managing Director Director Joint Managing Director Executive Director Section IV Particulars of the Project Iodine story The company is putting up a project to manufacture intermediates at Pithampur. Theses intermediates are primarily for contrast media APIs. These are iodine based. Currently, these products are imported. Producing within India should save valuable foreign exchange and also ensure un-interrupted supply of good quality of higher intermediates to API and formulation manufacturers. This will enable the Indian API manufacturers to be the world leaders in field of iodine based contrast media products. 4.01 Products : 2,4,6-Triiodo-5-amino isophthalic acid dichloride (Iopamidol/Iohexol stag-ii), L-5-(2- acetoxypropionylamino)-2, 4, 6-triiodoisophthalic acid dichloride (Iopamidol stage- III), 4-(2-amino-1-hydroxy-ethyl)phenol hydrochloride ((±)-Octopamine hydrochloride) 4.02 Capacity 200 MT annually 4.03 Project management during construction/ operation The project will be implemented under the supervision of our technical personnel layout shall be finalized in consultation with Architect. 4.04 Location of Land: Pithampur 4.05 Buildings as per plan to be finalised.

. 4.06 Details of Plant & Machinery - Attached 4.07 Raw Material/ Components - Attached 4.09 Power - Power Demand 500KVA 4.10 Stand By Arrangement - One D.G. Set of 250 KVA Capacity. 4.11 Water - Requirement is approx.. 50 KL per day. 4.12 Air since it is intermediate plant, we estimate the no AHU will be required. 4.13 Effluents ETP shall be installed 4.14 Schedule of Implementation a. Commencement & Completion - one to one half year from the date of commencement b. Civil Work - One year from the date of commencement of civil work c. Plant & Machinery - 6 months from the date of releasing purchase order and payment d. Erection - 3-6 months after receiving the equipment e. Commissioning - 3 months 6 months f. Trial Run - 3 months for dummy trials and Process trials as per R&D schedule g. Commercial Production- 1 to 3 months from the date of trial batches 4.15 Employment potential - approximately 100

SECTION V Financials Profitability Statement: Cost of Project Land & Site Development 3 crore Builidings/Civil Construction 3 crore Plant & Machinery 10 crore Electrical Installation -1 crore ETP 1 crore Other Utilities & Fixed Assets - 1 crore Margin money for Working Capital 1 crore Total 20 crore Source of Funds Loan from Bank/ FI 17 crore Own/ Share 3 crore Total 20 crore Projected Financials for Pithampur Project (in lacs) Details 2016-17 2017-18 2018-19 Total Sales 514,864,000 514,864,000 514,864,000 1,544,592,000 Less - Raw Material Cost 359,799,310 359,799,310 359,799,310 1,079,397,929 interest and depreciation 36,983,500 36,983,500 36,983,500 110,950,500 overheads 43,991,022 43,991,022 43,991,022 131,973,066 Transport 7,770,000 7,770,000 7,770,000 23,310,000 Packaging 774,060 774,060 774,060 2,322,180

working capital 14,041,184 14,041,184 14,041,184 42,123,552 Total Exp 463,359,076 463,359,076 463,359,076 1,390,077,228 Profit 51,504,924 51,504,924 51,504,924 154,514,772 List of API Sr. No. Name CAS 1 Quetiapine Fumarate 111974-69-7 2 Paroxetine hydrochloride 61869-08-7 3 Valacyclovir hydrochloride 124832-26-4 4 Benfotiamine 22457-89-2 5 Benzocaine 94-09-7 6 Ractopamine hydrochloride 90274-24-1 API Intermediates 1 2,4,6-Triiodo-5-amino isophthalic acid dichloride (Iopamidol/Iohexol stag-ii) 2 L-5-(2-acetoxypropionylamino)-2, 4, 6- triiodoisophthalic acid dichloride (Iopamidol stage-iii) 3 (RS)-4-(2-amino-1-hydroxy-ethyl)phenol hydrochloride ((±)-Octopamine hydrochloride) 37441-29-5 60166-91-8 770-05-8 Details of Capital Equipments - Sr No. Equipment Amt in lacs 1 GLR with acessories and load cell 20 2 GLR for ICL storage 10 3 SCRUBBER 5 4 gas manifold (flow meter) 5 5 chain pully 2 6 GLR with acessories 17

7 GLR with acessories (high vacuum distillation) 15 8 SS with accessories (high vacuum) 15 9 SS with accessories 20 10 Scrubber 5 11 Glass receivers jacketed 15 12 SS receivers 15 13 GLR with acessories 120 14 GLR with acessories 140 15 GLR with acessories 15 16 GLR with acessories 30 17 glass dosing tanks 4 18 Ppneutch 0.5 19 PP dosing tank 2 20 MSRL centrifuge 24 21 tray drier PP trays 45 22 PP storage tank 8 23 PP scrubber 5 24 PP storage tank 16 25 PP storage tank 5 26 sparkler filter 6 27 SS micron filter 4 28 PP storage tank 2 29 SSR for recovery 50 30 PP storage tank 15 31 Electronic balance 2 32 Hoist 4 33 DM water system 8 34 fire hydrant 25 35 ETP 100 36 Land 270 37 building construction 200 38 Misc.expenses 70 39 Electrical fitting and wiring 100 40 Pipe lines, valves, flanges, bends, etc 150 41 staturory approvals 25 42 AHU for store 15 43 project consultancy 25 44 GC with head space 30 45 HPLC 25 46 ph 1 47 KF 1.5 48 Autotitrator 1.5 49 Sonicator 2 50 Balance 8

51 HPLC water system 5 52 Furniture 25 53 UPS 20 54 Misc.expenses 21 55 Boiler 30 56 Brine plant 50tr 25 57 Hot water system 5 58 Cooling tower 8 59 Water ejectors 9 60 DG set for power back up 250kva 25 61 Thermic fluid boiler 10 62 Oil vacuum pump (1mm) 20 63 Misc.expenses 20 Total 1947