Vevo The Ultimate Preclinical Imaging Experience

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Vevo 3100 The Ultimate Preclinical Imaging Experience

2 3 Introducing The World s First One-Touch Preclinical Imaging Platform The is a new and innovative platform created for the future of imaging. It combines ultra high-frequency ultrasound imaging, quantification and education in a convenient all-in-one touchscreen platform. Its intuitive control panel allows customizable workflow for rapid data acquisition, providing extremely high-throughput when needed and saving you time! At the sweep of your hand, it responds so quickly and intelligently to your imaging needs, you ll know it was created precisely for researchers like you. With lightweight ergonomically designed MX series transducers, imaging has never been easier and clearer. The enables you to obtain in vivo anatomical, functional, physiological and molecular data simultaneously, all in real-time and with a resolution down to 30 µm. Customizable User Interface Easily customize the interface to suit your needs. Swipe, Drag, Tap, Pinch or Spread optimized workflow is always at your fingertips. Vevo HD Image Technology This revolutionary technology reduces speckle noise and artifacts in images while preserving and enhancing critical tissue information all in real-time. Real-Time Learning For instant reference, scan with onboard stepby-step imaging tutorials and guides. TOUCH CUSTOMIZE VISUALIZE

4 5 Imaging Platform Vevo HD Image Technology visualize your data like never before Intuitive touchscreen interface for all user types Customizable workflow for rapid data acquisition Anatomical, hemodynamic, functional and molecular data all in one platform Compact imaging system over 40% reduction in both size and weight State-of-the-art ultra high-frequency electronics operating up to 70 MHz MULTIPLE RESEARCH AREAS: CARDIOVASCULAR, CANCER, DEVELOPMENTAL BIOLOGY, CONTRAST IMAGING, REGENERATIVE MEDICINE, DRUG DEVELOPMENT, UROLOGY, REPRODUCTIVE MEDICINE AND MORE! Conduct in-depth analysis with advanced measurement and calculation packages on the Vevo LAB software

6 7 MX Transducers Vevo Imaging Station The MX series of ultra high-frequency linear array transducers are custom-designed and optimized to operate in harmony with the Imaging System. MX transducers are available across a wide range of frequencies to provide the flexibility you need for your small animal studies. Examples include: Transducer Animal Applications Standardize image acquisition and quantification to ensure repeatable, reproducible results and high-throughput workflow for multiple animal studies. Warmed platform for maintaining optimal physiological conditions for small animals Integrated & displayed physiological monitoring ECG, heart rate, core temperature, respiration, blood pressure Transducer mounting system for precision and hands-free scanning Precision micro-injection system for injections or extraction procedures Compatible with the Vevo Compact Anesthesia System and the Vevo E-Box MX250 13-24 MHz Axial Resolution: 75 µm Cardiovascular and Abdominal Tumors All MicroMarker contrast applications MX550D 22-55 MHz Axial Resolution: 40 µm Abdominal, Reproductive, Cardiovascular, Embryology Tumors MX700 30-70 MHz Axial Resolution: 30 µm Vascular, Embryology Superficial tissue Ophthalmology For a complete list of MX transducers and more specifications, please visit our website. HIGH-RESOLUTION LONGITUDINAL REAL-TIME HIGH-THROUGHPUT

8 9 Vevo Technology Innovation The original Vevo platform was the world s first commercially available ultra high-frequency ultrasound imaging system. High anatomical resolution, physiological and microcirculation quantification, and molecular data have enabled scientists worldwide to visualize and measure what was previously unattainable. As the undisputed leader in real-time in vivo micro-imaging systems, VisualSonics once again advances the world of preclinical research with the imaging platform. WORLD S FIRST ONE-TOUCH PRECLINICAL IMAGING PLATFORM 2000 VS40 2006 Vevo 770 2011 Vevo LAZR 2014 Launched 2003 Vevo 660 2008 Vevo 2100 2013 Vevo 1100 TRANSLATABLE IMAGING AND CALCULATIONS FROM BENCH TO BEDSIDE

10 11 Vevo Support The advanced technology of the high resolution imaging platform is accompanied by an integrated approach to service and support. Applications Support and Training Customized to Your Needs Customer On-Site Training VSI University Courses tailored hands-on education Online Resources Live Webinars Imaging Guides and Videos Grant Support Program Vevo Ambassador Program and more Technical Support On-site Support Online Support For additional resources, support or service requests, visit our website: www.visualsonics.com STUDY A WIDE RANGE OF ANIMAL MODELS FROM EMBRYOS TO ADULTS

VisualSonics, Vevo, MicroMarker, RMV, EKV, MicroScan, Insight Through In Vivo Imaging are trademarks and registered trademarks of FUJIFILM SonoSite, Inc. in various jurisdictions. All other trademarks are the property of their respective owners. 2014 VisualSonics Inc. All rights reserved. www.visualsonics.com