IMT-Bucharest: Networking in micro- nanobiotechnologies Dan Dascalu National Institute for R&D in Microtechnologies (IMT-Bucharest)
IMT in brief IMT (founded in 1993) was the first research unit from Eastern Europe devoted on microtechnologies (micro-system technologies). Becoming a national institute in 1996, IMT also included a nanotechnology laboratory. IMT hosts a Centre for technological transfer (CTT-Baneasa) and in the main driving force behind the science and technology park of micro- and nanotechnologies MINATECH-RO, acting as a technological pole. Since 2002, IMT was leading a virtual nanobiotechnology centre, called CENOBITE. This infrastructure, financed by a national programme, was using the model of NoE. Later on, IMT become full member of four NoEs from FP6, plus an associate member of Nano2Life. In 2005 IMT is full partner of 9 FP 6 research projects (and it is also involved in 5 SSA and CA).
Content of this presentation IMT was leading the consortium preparing (2003-2004) a strategic study for the field New materials, micro- and nanotechnologies at the national level. IMT is now a member of the consortium developing (2005-2006) a national strategy in research for 2007-2013 and foresight studies. This presentation will briefly review some activities of IMT related to: Virtual centre of nanobiotechnologies (CENOBITE) Preparation to join activities in the Nanomedicine European technological platform Networking in micro-nano-biotechnologies at the national, regional and European scale
CENOBITE - Research Centre in Nanobiotechnologies The CEntre of research in nanobiotechnology (CENOBITE), created in 2002, is a virtual centre of research at the national level, based upon the strong cooperation and integration of activities of 10 research centres. These centres are active in biology, medicine, pharmacology, chemistry, biochemistry, physics, micro and nanotechnologies. The research topic is selected from the 6th Framework Programme of European Union, with nanobiomaterials included. It is mainly about nanobiotechnology for health Strategic objectives: Rapid creation in Romania of a critical mass of specialists in advanced research and for the future and emerging technologies a synergy between the existing activities and the future trends of the participant centres is to be created. Supplying elements for correlating the national research programmes MATNANTECH, VIASAN, BIOTEH, CERES AND MENER Financed from the national R&D programme MATNANTECH. Activities funded: Acquisition of equipments of common interest
Members of CENOBITE Centre of Microsystems for Bio-medical and Environmental applications, National Institute for R&D in Microtechnologies(IMT-Bucharest); contact: Dr. Carmen Moldovan (cmoldovan@imt.ro) Centre of Nanotechnologies (under the aegis of the Romanian Academy) from the National Institute for R&D in Microtechnologies (IMT-Bucharest); contact: Dr. Irina Kleps (irinak@imt.ro) Centre of Laser-Surface-Plasma Interactions from the National Institute for R&D for Laser, Plasma and Radiation; contact: Prof. Dr. Ion N. Mihailescu (mihailes@ifin.nipne.ro) Department of Neuro-Psycho-Pharmacology from the Centre of Medical-Military Research; contact: Dr. Mihail Hinescu (mhinescu@yahoo.com) Group of Ceramic Nanocristalline Materials from the Research Institute for Nonferrous and Rare Metals; contact Dr. Radu Robert Piticescu (rpiticescu@imnr.ro) Centre for Molecular Biology from the Faculty of Biology, University of Bucharest; contact: Dr. Marieta Costache (costache@bio.bio.unibuc.ro) Centre for Cellular and Molecular Pharmacology from the National Institute for Chemical-Pharmaceutical R&D; contact Dr. Mihaela Albulescu (mihaela@ncpri.ro) Centre for Microbiology from the Institute of Biology (Romanian Academy); contact: Dr. Lucia Dumitru (lucia.dumitru@ibiol.ro) Centre of Glicobiology from the Institute of Biochemistry (Romanian Academy); contact: Dr. Stefana Petrescu (Stefana.Petrescu@biochim.ro) Laboratory of Bioactive and Biocompatible Polymers from the Institute for Macromolecular Chemistry Petru Poni (of the Romanian Academy), Iasi; contact: Dr. Gabrielle Charlotte Chitanu (chita@icmpp.tuiasi.ro)
The main topics/directions that could be developed by CENOBITE members: Lab-on-chips; Nanoparticles with modified surface; Advanced drug delivery and other areas of nanosystem and nanoelectronics integration to biological entities; Electronic detection of biological entities; Processing, manipulation and detection of biological molecules/entities; Interfaces to biological entities; Projects in nanobiotechnology: Bio-chips for electrochemical activity investigation of biological media (2001-2002) Porous silicon matrix for biomedical applications (2001-2004) Silicon-chip-based bioanalytical microdevices (2003-2005) Microsystem for controlled drug delivery (2003-2005) Nanostructurated silicon membranes technology for pharmaceuticall microdevices (2003-2005) Microprobe for stimulation and recording of neural activity (2003-2005);
www.romnet.net/nano/
Members
Contact point for NanoMedicine Romania: National Institute for R&D in Microtechnologies (IMT-Bucharest), nanobio@imt.ro The European NANOMEDICINE Technology Platform NanoMedicine - Nanotechnologies for Medical Applications The Romanian network addressed to nanomedicine is part of the national (Romanian) micro and nanotechnology network ROMNET-NANO, supported by the EU project ROMNET-ERA. Participation to Nanomedicine-Ro 58 participants: 22 participants from 10 National R&D Institutes 5 participants from 3 R&D Institutes of the Romanian Academy 3 participants from 3 R&D Institutes 17 participants from 11 Universities 6 participants from 6 SMEs 2 participants from 2 Hospitals
Institutions participating to Nanomedicine-Ro - 1 INCD pentru Microtehnologie IMT-Bucuresti INCD in Inginerie Electrica ICPE-CA, Laboratorul Cercetari Materiale Micro si Nanostructurate si Aplicatii INCD pentru Metale Neferoase si Rare - IMNR INCD pentru Chimie si Petrochimie, ICECHIM, Bucuresti INCD pentru Fizica Laserilor, Plasmei si Radiatiei (Laboratorul de depuneri in plasma la temperatura joasa; Centrul interactiuni laser-suprafata-plasma; Laboratorul pentru acceleratoare; Sectia laseri, Laboratorul de Fotochimie cu Laseri) INCD Textile Pielarie, Sucursala Institutul de Cercetare Pielarie Institutul de Chimie Fizica al Academiei Romane (Laboratorul de Stiinta Materialelor Oxidice; Laborator Coloizi, Laboratorul de Termodinamica Chimica) Institutul de Biologie al Academiei Romane Institutul National de Fizica Materialelor Institutul Pasteur Bucuresti IP Devel Bucuresti Spitalul Clinic Caritas Spitalul Clinic Universitar Bucuresti, Clinica de Medicina Interna Universitatea din Bucuresti (Facultatea de Chimie; Laboratorul pentru controlul calitatii si monitorizarea proceselor) Universitatea Politehnica Bucuresti, Facultatea de Chimie Industriala Universitatea de Medicina si Farmacie Carol Davila, Catedra de Biofizica si Biotehnologie Celulara Donna Maria SRL, Bucuresti METAV CD SA DDS Diagnostic Telemedica SA SITEX 45
Institutions participating to Nanomedicine-Ro - 2 INCD pentru Tehnologii Izotopice si Moleculare, Laboratorul de Fizica Sistemelor Nanostructurate Multifunctionale Universitatea Tehnica Cluj-Napoca, Facultatea de Automatica si Calculatoare, Automation Department Cluj-Napoca Universitatea Babes-Bolyai, Facultatea de Fizica Universitatea din Craiova, Facultatea de Ingineria si Managementul Sistemelor Tehnologice Universitatea "Dunarea de Jos", Galati, Facultatea de Metalurgie si Stiinta Materialelor Craiova Galati Institutul de Chimie Macromoleculara "Petru Poni" al Academiei Romane, Iasi INCD pentru Fizica Tehnica, Iasi Institutul de Cercetari Biologice Iasi Universitatea Al.I.Cuza, Iasi Iasi Universitatea Tehnica Gh.Asachi, Iasi, Facultatea de Chimie Industriala Universitatea de Medicina si Farmacie "Gr. T. Popa" Spitalul "Sf. Spiridon", Laboratorul de Imunologie si Genetica, Clinica Oncologica Institutul de cercetari produse auxiliare organice INCD pentru tehnologii criogenice si izotopice ICSI Rm. Valcea Medias Ramnicu Valcea Institutul de cercetare a materiei condensate INCEMC Timisoara Universitatea de Stiinte Agricole a Banatului din Timisoara, Facultatea de Medicina Veterinara Timisoara: Catedra Chirurgie Laboratorul de Biologie celulara- Histologie-Embriologie Timisoara
http://eroom.nano-link.net/romnet/
INTEGRATED RESEARCH NETWORK DEVOTED TO NANOBIOTECHNOLOGY FOR HEALTH (ROMANIAN NANOMEDICINE NETWORK)- RO-NANOMED, proposal June 2005 This proposal is devoted to the creation and development of an integrated research network in the field of nanobiotechnology for health. This network is targeting integration into the European technological platform NanoMedicine. This proposal involves all 9 partners collaborating previously in a network CENOBITE) financed (2002-2004) from the national RTDI programme MATNANTECH (New Materials, Micro- and Nanotechnologies). The focus of this very successful CENOBITE has been already on biomedical applications (with significant multi-disciplinary scientific results), and the present RO-NANOMED is a natural continuation and extension of the previous network. The continuation is worthwhile for a number of reasons. First, the previous network is now considerably expanded (from 9 to 14 members, plus other 6 associate partners acting as subcontractors; these 20 entities belong to the four biggest university centres of Romania) and it is moving on the application side (with 3 hospitals, 3 universities of medicine and pharmacy, 2 medical research units). Stage 3 of RO-NANOMED should consolidate a true national network and include companies.
INTEGRATED RESEARCH NETWORK DEVOTED TO NANOBIOTECHNOLOGY FOR HEALTH (ROMANIAN NANOMEDICINE NETWORK)- RO-NANOMED, proposal June 2005 (continued) Secondly, the new proposal is financing directly the research, grouped in a total of 15 mini-projects, which are clustered on three key directions of regenerative medicine, targeted drug-delivery and nano-diagnostics (exactly the topics of NanoMedicine ETP). Further integration of activities is provided not only by financing common projects, but also by the creation of clean technological space (the so-called NANOBIOLAB) in the emerging science and technological park MINATECH-RO. Most of the investments in RO-NANOMED go in this common laboratory, with specific equipments allowing the manipulation of biological material. Moreover, the partners agreed to share the use of some key existing instrumentation, whereas mobility inside network and joint education and training activities will be common place. Finally, integration in the NanoMedicine ETP will be pursued along the whole duration of the project. The previous experience of the common work, as well as the focus on the main scientific topics in NanoMedicine (see above) will facilitate European cooperation. The technological orientation plus wide medical expertise provides a chance for Romanian partners to enter in FP7 consortia, cooperate with commercial companies and become active members of ETP working groups. The RO-NANOMED consortium is coordinated by three core members with outstanding experience in European projects, whereas the coordinator is also directing a network of networks at the European scale.
Partners List and Associated Partners: P1 (CO)/contractor:National Institute for R&D in Micro technologies (IMT-Bucharest); P2/contractor:National Institute for Laser, Plasma and Radiation Physics, Bucharest (INFLPR); P3/contractor:Institute for Macromolecular Chemistry Petru Poni Iasi (Petru Poni); P4/contractor:Institute of Biochemistry of the Romanian Academy, Bucharest; P5/contractor:National Institute for Chemical- Pharmaceutical R&D, ICCF-Bucharest; P6/contractor:R&D National Institute for Nonferrous and Rare Metals; P7/contractor:Institute of Biology of the Romanian Academy, Bucharest; P8/contractor:University of Bucharest, Faculty of Biology; P9/contractor:Scientific Research Center for Military Medicine, Bucharest; P10/contractor: Victor-Babes University of Medicine and Pharmacy Timisoara; P11/contractor:R&D National Institute in the Pathology and Medical Science Domain Victor Babes - Bucharest; P12/contractor:National Institute for Electrical Engineering, Bucharest; P13/contractor:R&D National Institute for Technical Physics; P14/contractor:University of Medicine and Pharmacy, Bucharest, Faculty of Pharmacology; PA15/associated: University of Medicine and Pharmacy Iasi; PA16/associated: University Politehnica of Bucharest; PA17/associated: Emergency Hospital Iasi; PA18/asociat: Emergency Hospital Floreasca, Bucharest; PA19/associated: Clinical Sf. Ioan Hospital Bucharest; PA20/associated: University of Agricultural Science and Veterinary Medicine Cluj-Napoca
IMT-BUCHAREST Networking in Eastern Europe (1) IMT-Bucharest is the coordinator of the FP6 Specific Support Actions ROMNET-ERA (ROManian inventory and NETworking for the integration in ERA), MINAEAST-NET (MIcro and NAnotechnologies going EASTern Europe through NETworking) and MINOS-EURONET (MIcro-NanOSystems EUROpean NETwork pursuing the integration of NMS and ACC in ERA). The main aim of the MINAEAST-NET project is networking in micro and nanotechnologies at the national scale, in Eastern Europe, according to the priority thematic areas 2 (IST) and 3 (NMP) from FP 6. MINAEAST-NET will establish a network of networks active in MNT called MINAEAST-NETwork, composed by networks of high quality centres of research at national level, which will be either existing or new (emerging).
IMT-BUCHAREST Networking in Eastern Europe (2) MINOS-EURONET is devoted to stimulating, encouraging and facilitating the participation of New Member States (NMS) and the Associated Candidate Countries (ACC) in the activities of IST. The networking (exchange of information) is the main objective of this project. MINOS-EURONET is starting with an enormous potential for networking at the European scale, and has the adequate means in achieving broad and effective dissemination in a unique pan European network of networks. The networking and dissemination in both projects are realized by different means, including: - common public and interactive electronic databases, in English, are implemented, displaying information about specialists, research centers, international research projects, databases for partner matching for specific FP6 calls. - the key tool for networking and dissemination is the communication platform eroom, a system of web pages with customized controlled access and multiple functionality: assisting networks and research organisations for preparing of a new proposal, organisation of various events, cooperation in a research project, assembling a scientific paper, etc. - electronic media (webpage http://www.minaeast.net e-mail, CD-ROMs), each project issuing their own informative electronic newsletter containing information about events organized by the projects, other events in the MNT area (courses, conferences, workshops), FP6 calls - publications (quarterly issuing of Micro and Nanotechnologies Bulletin, newsletters columns in MST News for information and partner search) - various events: conferences, seminars, workshops, exhibitions, meetings