A LEADING GLOBAL HEALTH CARE GROUP. Frankfurt stock exchange (DAX30): FRE US ADR program (OTC): FSNUY

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A LEADING GLOBAL HEALTH CARE GROUP Frankfurt stock exchange (DAX30): FRE US ADR program (OTC): FSNUY www.fresenius.com/investors

SAFE HARBOR STATEMENT This presentation contains forward-looking statements that are subject to various risks and uncertainties. Future results could differ materially from those described in these forwardlooking statements due to certain factors, e.g. changes in business, economic and competitive conditions, regulatory reforms, results of clinical trials, foreign exchange rate fluctuations, uncertainties in litigation or investigative proceedings, and the availability of financing. Fresenius does not undertake any responsibility to update the forward-looking statements contained in this presentation. Page 2

A GLOBAL LEADER IN HEALTHCARE PRODUCTS AND SERVICES ~ 27.6 bn in Sales (as of Dec. 31, 2015) Global presence in 100+ countries Strong portfolio of products (30% of sales) and services (70% of sales) Total Shareholder Return: 10-year : ~20% 222,000+ employees worldwide (as of Dec 31, 2015) Page 3

STRONG, DIVERSIFIED PRODUCT AND SERVICE PORTFOLIO Ownership: 31% Ownership: 100% Ownership: 100% Ownership: 77% Dialysis Products Healthcare Services Hospital Supplies and Services Hospital Operations Hospital Projects and Services Sales 2015: US$16.7 bn Sales 2015: 6.0 bn Sales 2015: 5.6 bn Sales 2015: 1.1 bn Page 4

AGING POPULATION AND HIGHER INCIDENCE OF CHRONIC DISEASES 60+ World population age 60+ will reach >2 bn by 2050 1 80+ World population age 80+ will reach ~400 million by 2050 1 In 2050, 80% of older people will live in Developing and Emerging Markets 1 52m Deaths due to Chronic Diseases are projected to increase from 38 million in 2012 to 52 million by 2030 2 Source: 1 WHO: 10 facts on aging and the life course (2014) 2 WHO: Global status report on non communicable diseases (2014) Page 5

INCREASING HEALTH CARE SPENDING Increasing health expenditure per capita (2013 vs. 2003 - USA US$9,146 (+52%), China: US$367 (+502%), India: US$61 (+154%) 1 By 2022, one third of all global health expenditure will occur in Emerging Economies 2 ~4% Health care spending in developed countries is growing steadily (2012-2022 with ~ 4% p.a. 2 ) Source: 1 World Bank: Health expenditure per capita (2013); 2 World Economic Forum: Health Systems Leapfrogging in Emerging Economies Project Paper (2014) Page 6

FRESENIUS MEDICAL CARE: GLOBAL DIALYSIS MARKET LEADER The world s leading provider of dialysis products and services treating >290,000 patients in 3,418 clinics 1 Provide highest standard of product quality and patient care Market Dynamics Global Dialysis Market 2015: ~US$73 bn; ~6% patient growth p.a. Growth Drivers: Aging population, increasing incidence of diabetes and high blood pressure, treatment quality improvements Dialysis products Dialysis services Complete therapy offerings Expansion in Care Coordination and global dialysis service opportunities; enter new geographies International 29% Sales 2015: US$16.7 bn North America 71% 1 As of Sep 30, 2015 Page 7

FRESENIUS MEDICAL CARE: STRONG TRACK RECORD OF GROWTH Sales in US$ million EBIT in US$ million 6% 3% 12,571 13,800 14,610 15,832 16,738 2,329 2,256 2,255 2,327 2,075 '11 '12 '13 '14 '15 '11 '12 '13 '14 '15 Page 8

FRESENIUS KABI: A LEADING GLOBAL HOSPITAL SUPPLIER Comprehensive product portfolio for critically and chronically ill patients Strong Emerging Markets presence Leading market positions in four product segments Market Dynamics Global Addressable Market 2015: > 33 bn Growth Drivers: Patent expirations, rising demand for health care services, higher health care spending in Emerging Markets Generic IV Drugs Clinical Nutrition Infusion Therapy Medical Devices / Transfusion Technology Emerging Markets 29% Focus on organic growth through geographic product rollouts and new product launches Sales 2015: 6.0 bn Europe 36% North America 35% Page 9

FRESENIUS KABI: IMPRESSIVE GROWTH Sales in million EBIT in million 8% 8% 5,950 1,189 3,964 4,539 4,996 5,146 803 934 926 873 '11 '12 '13 '14 '15 '11 '12 '13 '14 '15 Page 10

FRESENIUS HELIOS: LEADING GERMAN HOSPITAL OPERATOR ~6% share in German acute care hospital market Strong track record in hospital acquisitions and operations High-quality medical care, e.g., mortality rate for heart failure and pneumonia below German average Comprehensive healthcare services coverage Acute Care Rehab Outpatient Market Dynamics German Acute Care Hospital Market: ~ 91 bn 1 Growth Drivers: Aging population leading to increasing hospital admissions, further market consolidation Majority of population has access to a HELIOS hospital within one hour s drive 1 111 hospitals >34,000 beds ~1.3 million inpatient admissions ~3.4 million outpatient admissions 1 German Federal Statistical Office 2015; total costs, gross of the German hospitals less academic research and teaching 1 As of Dec 31, 2015 Page 11

FRESENIUS HELIOS: EXCELLENT SALES AND EBIT DEVELOPMENT Sales in million EBIT in million 16% 5,244 5,578 24% 553 640 2,665 3,200 3,393 270 322 390 '11 '12 '13 '14 '15 '11 '12 '13 '14 '15 Page 12

FRESENIUS VAMED: LEADING GLOBAL HOSPITAL PROJECTS AND SERVICES SPECIALIST Manages hospital construction/expansion projects (51% of sales) and provides services (49% of sales) for health care facilities worldwide Projects Services Growth Drivers: Market Dynamics Emerging Market demand for building and developing hospital infrastructure Outsourcing of non-medical services from public to private operators Offers project development, planning, turnkey construction, maintenance as well as technical management, and total operational management Strong track record: More than 760 projects in 78 countries completed Emerging Markets 26% Sales 2015: 1.1 bn Europe 74% Page 13

FRESENIUS VAMED: STEADY SALES AND EBIT GROWTH Sales in million EBIT in million 11% 1.020 1.042 1.118 51 10% 55 59 64 737 846 44 '11 '12 '13 '14 '15 '11 '12 '13 '14 '15 Page 14

FRESENIUS GROUP: EXCELLENT FINANCIAL PERFORMANCE DRIVEN BY ORGANIC GROWTH AND ACQUISITIONS Sales in billion EBIT in million 7.9 10.8 14% 11.4 12.3 14.2 16.0 16.5 19.3 20.3 23.2 27.6 969 1,444 15% 1,609 1,727 2,054 2,418 2,563 3,075 3,045 3,158 3,958 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Net income in million Earnings per share in 222 330 20% 410 450 514 660 770 938 1,051 1,086 1,423 16% 0.59 0.72 0.88 0.95 1.06 1.36 1.58 1.81 1.96 2.01 2.61 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Page 15

FRESENIUS GROUP: CONSISTENT CASH GENERATION AND PROVEN TRACK RECORD OF DELEVERAGING CFFO margin FCF margin (before acquisitions & dividends) % % 14 10 13 12 11 10 9 9.9 9.8 11.4 8.7 11.0 12.0 10.3 12.6 11.4 11.1 12.0 8 6 4 5.7 4.5 5.6 2.7 6.3 7.4 5.7 7.7 6.3 5.4 6.8 8 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Capex in % of sales Net Debt / EBITDA 1 % 7 6 5 4 4.5 5.6 6.2 6.2 4.7 4.7 4.8 5.2 5.3 5.8 5.5 4,0 3,5 3,0 2,5 2.3 3.0 2.6 3.6 3.0 2.6 2.8 2.5 2.5 3.4 2.7 3 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2,0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 1 2011-2015 adjusted due to debt issuance cost restatement (U.S. GAAP standard ASU 2015-03) Page 16

TOTAL SHAREHOLDER RETURN Fresenius Group:, ROUNDED Dividend Development and Total Shareholder Return 26% 20% 17% 14% 15% 9% 8% 8% 10% 10% 4% 2% DAX S&P 500 MSCI World Health Care Fresenius DAX S&P 500 MSCI World Fresenius DAX S&P 500 MSCI World Fresenius Health Care Health Care 15 years 10 years 5 years Source: Bloomberg; dividends reinvested Page 17

FRESENIUS GROUP: 2016 FINANCIAL OUTLOOK BY BUSINESS SEGMENT Fresenius Kabi Sales growth organic EBIT constant currency low single-digit roughly flat Fresenius Helios Sales growth organic EBIT 3% 5% 670 700 m Fresenius Vamed Sales growth organic EBIT growth 5% 10% 5% 10% Page 18

FRESENIUS GROUP: 2016 FINANCIAL GUIDANCE Sales growth constant currency 6% 8% Net income growth 1 constant currency 8% 12% 1 Net income attributable to shareholders of Fresenius SE & Co. KGaA; 2015 before special items Page 19

FRESENIUS GROUP: NEW MID-TERM GROWTH TARGETS FY 2019 36-40 billion in sales 2.0-2.25 billion in net income - At comparable exchange rates - Includes small and mid-size acquisitions - EAT at mid-point of mid-term target: 10.5 % (Previous implied EAT of mid-term target: 8.4 %) Net income attributable to shareholders of Fresenius SE & Co. KGaA; 2015 before special items Page 20

INVESTMENT HIGHLIGHTS Diversified revenue and earnings base with four strong business segments Superior shareholder returns Leading positions in non-cyclical markets with reliable growth Prudent financial management Strong earnings development and cash flow generation Promising future growth opportunities Page 21

SHARE INFORMATION Share key facts Number of shares 1 545,739,430 WKN / ISIN 578560 / DE0005785604 Ticker symbol FRE Bloomberg symbol FRE GR Reuters symbol FREG.de ADR key facts Ratio ADR CUSIP / ISIN Ticker symbol Exchange Structure Depositary bank 4 ADRs = 1 ordinary share 35804M105 / US35804M1053 FSNUY OTCQX International Premier Sponsored Level I ADR Deutsche Bank 1 As of January 31, 2016 Page 22