Material Safety Data Sheet NFPA HMIS Personal Protective Equipment 2 0 Health Hazard Fire Hazard 2 0 See Section 5. Section. Chemical Product and Company Identification Common Name/ Trade Name Manufacturer Commercial Name(s) Synonym Chemical Name Nalidixic acid SPECTRUM CHEMICAL MFG. CORP. 4422 S. SAN PEDRO STREET GARDENA, CA 90248 -Ethyl-,4-dihydro-7-methyl-4-oxo-,8-naphthyridine-3-carboxylic acid Catalog Number(s). CAS# RTECS TSCA CI# N006, NA05 389-08-2 QN2885000 IN CASE OF EMERGENCY CHEMTREC (24hr) 800-424-9300 Page Number: TSCA 8(b) inventory: No products were found. Chemical Family Chemical Formula Supplier C2H2N2O3 SPECTRUM CHEMICAL MFG. CORP. 4422 S. SAN PEDRO STREET GARDENA, CA 90248 CALL (30) 56-8000 Section 2.Composition and Information on Ingredients Name CAS # Exposure Limits TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight ) Nalidixic acid 389-08-2 00 Toxicological Data on Ingredients Nalidixic acid: ORAL (LD50): Acute: 60 mg/kg [Rat]. 572 mg/kg [Mouse]. Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant). Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant). CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: The substance is toxic to the nervous system, mucous membranes. Repeated or prolonged exposure to the substance can produce target organs damage.
Nalidixic acid Page Number: 2 Section 4. First Aid Measures Eye Contact Immediately flush eyes with running water for at least 5 minutes, keeping eyelids open. Cold water may be used. Skin Contact Serious Skin Contact After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing. Inhalation Allow the victim to rest in a well ventilated area. Seek immediate medical attention. Serious Inhalation Ingestion Serious Ingestion Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances May be combustible at high temperature. These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...). Explosion Hazards in Presence of Various Substances Risks of explosion of the product in presence of mechanical impact: Risks of explosion of the product in presence of static discharge: Fire Fighting Media and Instructions Fire Hazards Explosion Hazards SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Material in powder form, capable of creating a dust explosion. Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.
Nalidixic acid Page Number: 3 Section 7. Handling and Storage Precautions Storage Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately and show the container or the label. Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizing agents. Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of a Large Spill Exposure Limits Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Solid crystalline powder.) Odor Molecular Weight ph (% soln/water) 232.24 g/mole Taste Color Colorless to light yellow. Boiling Point Decomposes. Melting Point 227 C (440.6 F) Critical Temperature Specific Gravity Vapor Pressure Not applicable. Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties See solubility in water, diethyl ether, acetone. Solubility Partially soluble in diethyl ether, acetone. Very slightly soluble in cold water. Section 0. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances The product is stable.
Nalidixic acid Page Number: 4 Corrosivity Non-corrosive in presence of glass. Corrosivity Polymerization No. Section. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Inhalation. Ingestion. Acute oral toxicity (LD50): 572 mg/kg [Mouse]. The substance is toxic to the nervous system, mucous membranes. Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant). Section 2. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The products of degradation are more toxic. Section 3. Disposal Considerations Waste Disposal Section 4. Transport Information DOT Classification Identification Not a DOT controlled material (United States). Not applicable. Special Provisions for Transport Not applicable.
Nalidixic acid Page Number: 5 DOT Section 5. Other Regulatory Information and Pictograms Federal and State Regulations California Proposition 65 Warnings Other Regulations No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 90.200). Other Classifications WHMIS (Canada) DSCL (EEC) Not controlled under WHMIS (Canada). R22- Harmful if swallowed. HMIS (U.S.A.) Health Hazard Fire Hazard Personal Protection 2 0 E National Fire Protection Association (U.S.A.) Health 2 0 Flammability Specific hazard WHMIS (Canada) DSCL (Europe) TDG (Canada) ADR (Europe) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Nalidixic acid Page Number: 6 Safety glasses. Section 6. Other Information MSDS Code References Other Special Considerations N3000 Validated by Sonia Owen on 8//2006. Verified by Sonia Owen. Printed 9/2/2006. CALL (30) 56-8000 Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.