SAFETY DATA SHEET. Any additional components in this kit are considered non-hazardous and, therefore, non-classifiable in accordance

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SAFETY DATA SHEET October 15, 2016 Date of Issue: Section 1. Identification Product Name: ProtOn Peroxidase Protein Labeling Kit Catalog No.: Any additional components in this kit are considered non-hazardous and, therefore, non-classifiable in accordance with the GHS Safety Data Sheet guidelines. Manufacturer/Supplier USA: EU Supplier United Kingdom: Vector Laboratories, Inc. 30 Ingold Road Burlingame, CA 94010 United States Tel: (650) 697-3600 Fax: (650) 697-0339 Email: vector@vectorlabs.com Section 2. Vector Laboratories Ltd. 3 Accent Park Bakewell Road, Orton Southgate Peterborough, PE2 6XS, United Kingdom Tel: (01733) 237999 Fax: (01733) 237119 Email: vector@vectorlabs.co.uk Hazards Identification GHS Classification: Acute toxicity, Oral - Category 2, H300 Acute toxicity, Inhalation - Category 2, H330 Acute toxicity, Dermal - Category 2, H310 Skin corrosion (Category 1B), H314 Serious eye damage (Category 1), H318 Acute aquatic toxicity (Category 1), H400 Chronic aquatic toxicity (category 1), H410 GHS Label: Signal Word: Danger Hazard Statements: H300 + H310 + H330 - Fatal if swallowed, in contact with skin or if inhaled H314 - Causes severe skin burns and eye damage. H318 - Causes serious eye damage. H410 - Very toxic to aquatic life with long lasting effects Precautionary Statements: P260 - Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P262 - Do not get in eyes, on skin, or on clothing. P264 - Wash skin thoroughly after handling. P270 - Do not eat, drink or smoke when using this product. P271 - Use only outdoors or in a well-ventilated area. P273 - Avoid release to the environment.

page 2 P280 - Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 - Wear respiratory protection. P301 + P310 + P330 - IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P304 + P340 + P310 - IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P362 Take off contaminated clothing and wash before reuse. P391 - Collect spillage. P403 + P233 - Store in a well-ventilated place. Keep container tightly closed. P405 - Store locked up. P501 - Dispose of contents/ container to an approved waste disposal plant. Section 3. Composition/Information on Ingredients Component: Sodium Cyanoborohydride CAS#: 25895-60-7 EC#: 247-317-2 % by weight: >30 <50% Section 4. First Aid Measures Inhalation: Skin contact: Eye contact: Ingestion: Move to fresh air. If not breathing, give artificial respiration. Obtain medical attention. Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital/ Obtain medical attention. Wash thoroughly with water for at least 15 minutes. Obtain medical attention. Do not induce vomiting. If person is conscious, wash out mouth with water. Obtain medical attention. Section 5. Fire Fighting Measures Suitable extinguishing media: Special protective equipment: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Use respirator. Toxic gases can be evolved. Section 6. Accidental Release Measures Wear protective clothing to prevent contact with eyes and skin. Ensure adequate ventilation. Collect on absorbent material and dispose of in accordance with federal, state and local environmental control regulations. Do not let product enter drains. Discharge into the environment must be avoided. Section 7. Handling and Storage Handling: Use only with adequate ventilation. Wear eye protection and compatible chemical-resistant gloves. Avoid contact with skin and eyes. Avoid inhalation of vapor or mist. Storage: Store in a refrigerator. Keep container tightly closed in a dry and well-ventilated place. Do not store near acids.

page 3 ProtOn Peroxidase Protein Labeling Kit Section 8. Exposure Controls/Personal Protection Exposure limits: Consult local authorities for acceptable exposure limits. Engineering controls: Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protection: Hand/Skin protection - Eye protection - Body protection - Respiratory protection - Compatible chemical-resistant gloves. Chemical safety goggles. The type of protective equipment must be selected according to the concentration and amount of dangerous substance at the specific workplace. Use respirators and components tested and approved under appropriate government standards. Section 9. Physical and Chemical Properties Appearance: Liquid Flash point: Odor: Autoflammability: ph: Vapor pressure: Boiling point: Relative density: 1.083 g/ml at 25 ºC (77 ºF) Melting point: Solubility: Section 10. Stability and Reactivity Chemical stability: Stable under recommended storage conditions. Conditions to avoid: Materials to avoid: Hazardous reactions/decomposition products: Carbon oxides, Nitrogen oxides, Borane/boron oxides, Sodium oxides.

page 4 Section 11. Toxicological Information Information on toxicological effects Acute Toxicity:. Reproductive Toxicity:. Carcinogenicity: IARC: Not component of this product presents at levels greater than or equal to 0.1 % is identified as probable, possible or confirmed human carcinogen by IARC. NTP: Not component of this product presents at levels greater than or equal to 0.1 % is identified as probable, possible or confirmed human carcinogen by NTP. OSHA: Not component of this product presents at levels greater than or equal to 0.1 % is identified as probable, possible or confirmed human carcinogen by OSHA. RTECS#: Not available Toxicity data: To the best of our knowledge, the chemical physical, and toxicological properties have not been thoroughly investigated. Section 12. Ecological Information. Section 13. Disposal Considerations Observe all federal, state and local environmental disposal regulations. Section 14. Transport Information DOT (US): Reportable Quantity (RQ): RID/ADR: IMDG: IATA:

page 5 Section 15. Regulatory Information SARA: SARA 302 - No chemicals in this material are subject to the reporting requirements. SARA 313 - The following components are subject to reporting levels: N, N-Dimethylformamide, CAS-No. 68-12-2 SARA 311/312 Hazards - Fire Hazard, Acute Health Hazard, Chronic Health Hazard Pennsylvania Right To Know Components: New Jersey Right To Know Components: California Prop. 65 components: WARNING: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. Section 16. Other Information The information contained in this Material Safety Data is believed to be accurate but it is the responsibility of the user to determine the applicability of these data to the formulation of necessary safety precautions. Vector Laboratories, Inc. shall not be held responsible for any damage resulting from the use of the above product or the information contained in this Material safety Data Sheet. Date of Issue or Revision: October 13, 2016 Section Revised: N/A