Material Safety Data Sheet Buffer Solution ph 10

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Material Safety Data Sheet Buffer Solution ph 10 ACC# 41118 Section 1 - Chemical Product and Company Identification MSDS Name: Buffer Solution ph 10 Catalog Numbers: AC258600000, AC258600010, AC258605000, S79929-2, NC9619330, NC9675629, NC9813035, SB116-1, SB116-10, SB116-20, SB116-500, XXMAR7701811, XXSB116200LI Synonyms: None Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887 Section 2 - Composition, Information on Ingredients CAS# Chemical Name Percent EINECS/ELINCS 7732-18-5 Water 978 231-791-2 6381-92-6 Disodium ethylenediaminetetraacetate dihydrate 10 unlisted 584-08-7 Potassium carbonate 06 209-529-3 12228-88-5 Potassium Borate 04 unlisted 1310-58-3 Potassium hydroxide 02 215-181-3 Section 3 - Hazards Identification Appearance: clear, colorless liquid Caution! May cause irritation Target Organs: None EMERGENCY OVERVIEW Potential Health Effects Eye: May cause eye irritation Skin: May cause mild skin irritation Ingestion: Low hazard for usual industrial handling May cause gastric disturbances and electrolytic imbalance Inhalation: May cause respiratory tract irritation Low hazard for usual industrial handling Chronic: No information found Section 4 - First Aid Measures Eyes: Get medical aid Gently lift eyelids and flush continuously with wate r Skin: Get medical aid if irritation develops or persists Flush skin with plenty of soap and water Ingestion: Get medical aid Do NOT induce vomiting If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water Inhalation: Remove from exposure and move to fresh air immediately If not breathing, give artificial respiration If breathing is difficult, give oxygen Get medical aid Notes to Physician: Treat symptomatically and supportively https://fscimagefisherscicom/msds/41118htm (1 of 6)7/23/2007 10:41:47 AM

Section 5 - Fire Fighting Measures General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion Use extinguishing media appropriate to the surrounding fire Substance is noncombustible Extinguishing Media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire Flash Point: Not available Autoignition Temperature: Not available Explosion Limits, Lower:Not available Upper: Not available NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0 Section 6 - Accidental Release Measures General Information: Use proper personal protective equipment as indicated in Section 8 Spills/Leaks: Absorb spill with inert material (eg vermiculite, sand or earth), then place in suitable container Avoid runoff into storm sewers and ditches which lead to waterways Clean up spills immediately, observing precautions in the Protective Equipment section Section 7 - Handling and Storage Handling: Wash thoroughly after handling Use with adequate ventilation Avoid contact with skin and eyes Keep container tightly closed Avoid ingestion and inhalation Storage: Store in a cool, dry place Section 8 - Exposure Controls, Personal Protection Engineering Controls: Good general ventilation should be sufficient to control airborne levels Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs Water none listed none listed none listed Disodium ethylenediaminetetraacetate none listed none listed none listed dihydrate Potassium carbonate none listed none listed none listed Potassium Borate none listed none listed none listed Potassium hydroxide 2 mg/m3 Ceiling none listed none listed OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical Disodium ethylenediaminetetraacetate dihydrate: No OSHA Vacated PELs are listed for this chemical Potassium carbonate: No OSHA Vacated PELs are listed for this chemical Potassium Borate: No OSHA Vacated PELs are listed for this chemical Potassium hydroxide: No OSHA Vacated PELs are listed for this chemical Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910133 or European Standard EN166 Skin: Wear butyl rubber gloves to prevent skin exposure Clothing: Wear appropriate protective clothing to minimize contact with skin Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910134 or European Standard EN 149 Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or https://fscimagefisherscicom/msds/41118htm (2 of 6)7/23/2007 10:41:47 AM

other symptoms are experienced Section 9 - Physical and Chemical Properties Physical State: Liquid Appearance: clear, colorless Odor: odorless ph: 10 Vapor Pressure: Not available Vapor Density: Not available Evaporation Rate:>10 (Ether=1) Viscosity: Not available Boiling Point: Not available Freezing/Melting Point:Not available Decomposition Temperature:Not available Solubility: soluble Specific Gravity/Density:Not available Molecular Formula:Solution Molecular Weight:Not available Section 10 - Stability and Reactivity Chemical Stability: Stable Conditions to Avoid: None reported Incompatibilities with Other Materials: None reported Hazardous Decomposition Products: None Hazardous Polymerization: Has not been reported Section 11 - Toxicological Information RTECS#: CAS# 7732-18-5: ZC0110000 CAS# 6381-92-6: AH4410000 CAS# 584-08-7: TS7750000 CAS# 12228-88-5 unlisted CAS# 1310-58-3: TT2100000 LD50/LC50: CAS# 7732-18-5: Oral, rat: LD50 = >90 ml/kg; CAS# 6381-92-6: CAS# 584-08-7: Oral, mouse: LD50 = 2570 mg/kg; Oral, rat: LD50 = 1870 mg/kg; CAS# 12228-88-5: CAS# 1310-58-3: Draize test, rabbit, skin: 50 mg/24h Severe; Oral, rat: LD50 = 273 mg/kg; https://fscimagefisherscicom/msds/41118htm (3 of 6)7/23/2007 10:41:47 AM

Carcinogenicity: CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65 CAS# 6381-92-6: Not listed by ACGIH, IARC, NTP, or CA Prop 65 CAS# 584-08-7: Not listed by ACGIH, IARC, NTP, or CA Prop 65 CAS# 12228-88-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65 CAS# 1310-58-3: Not listed by ACGIH, IARC, NTP, or CA Prop 65 Epidemiology: No information found Teratogenicity: No information found Reproductive Effects: No information found Mutagenicity: No information found Neurotoxicity: No information found Other Studies: Section 12 - Ecological Information Ecotoxicity: No data available No information available Environmental: No information reported Physical: No information available Other: None Section 13 - Disposal Considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste US EPA guidelines for the classification determination are listed in 40 CFR Parts 2613 Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification RCRA P-Series: None listed RCRA U-Series: None listed Section 14 - Transport Information US DOT Canada TDG Shipping Name: Not regulated as a hazardous material Not Regulated Hazard Class: UN Number: Packing Group: Section 15 - Regulatory Information US FEDERAL TSCA CAS# 7732-18-5 is listed on the TSCA inventory CAS# 6381-92-6 is not on the TSCA Inventory because it is a hydrate It is considered to be listed if the CAS number for the anhydrous form is on the inventory (40CFR7203(u)(2)) CAS# 584-08-7 is listed on the TSCA inventory CAS# 12228-88-5 is not on the TSCA Inventory because it is a hydrate It is considered to be listed if the CAS number for the anhydrous form is on the inventory (40CFR7203(u)(2)) CAS# 1310-58-3 is listed on the TSCA inventory Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List Chemical Test Rules https://fscimagefisherscicom/msds/41118htm (4 of 6)7/23/2007 10:41:47 AM

None of the chemicals in this product are under a Chemical Test Rule Section 12b None of the chemicals are listed under TSCA Section 12b TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA CERCLA Hazardous Substances and corresponding RQs CAS# 1310-58-3: 1000 lb final RQ; 454 kg final RQ SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ SARA Codes CAS # 6381-92-6: immediate CAS # 584-08-7: immediate CAS # 1310-58-3: immediate, reactive Section 313 No chemicals are reportable under Section 313 Clean Air Act: This material does not contain any hazardous air pollutants This material does not contain any Class 1 Ozone depletors This material does not contain any Class 2 Ozone depletors Clean Water Act: CAS# 1310-58-3 is listed as a Hazardous Substance under the CWA None of the chemicals in this product are listed as Priority Pollutants under the CWA None of the chemicals in this product are listed as Toxic Pollutants under the CWA OSHA: None of the chemicals in this product are considered highly hazardous by OSHA STATE CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ CAS# 6381-92-6 is not present on state lists from CA, PA, MN, MA, FL, or NJ CAS# 584-08-7 is not present on state lists from CA, PA, MN, MA, FL, or NJ CAS# 12228-88-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ CAS# 1310-58-3 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts California Prop 65 California No Significant Risk Level: None of the chemicals in this product are listed European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes WGK (Water Danger/Protection) CAS# 7732-18-5: No information available CAS# 6381-92-6: 2 CAS# 584-08-7: 1 CAS# 12228-88-5: No information available CAS# 1310-58-3: 1 Canada - DSL/NDSL CAS# 7732-18-5 is listed on Canada's DSL List CAS# 6381-92-6 is listed on Canada's DSL List CAS# 584-08-7 is listed on Canada's DSL List CAS# 1310-58-3 is listed on Canada's DSL List Canada - WHMIS This product has a WHMIS classification of Not controlled This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations Canadian Ingredient Disclosure List CAS# 584-08-7 is listed on the Canadian Ingredient Disclosure List https://fscimagefisherscicom/msds/41118htm (5 of 6)7/23/2007 10:41:47 AM

CAS# 1310-58-3 is listed on the Canadian Ingredient Disclosure List Section 16 - Additional Information MSDS Creation Date: 2/24/1999 Revision #5 Date: 3/16/2007 The information above is believed to be accurate and represents the best information currently available to us However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use Users should make their own investigations to determine the suitability of the information for their particular purposes In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages https://fscimagefisherscicom/msds/41118htm (6 of 6)7/23/2007 10:41:47 AM