Fast Facts. Trinseo MAGNUM ABS Resins (Acrylonitrile Butadiene Styrene) for Medical Applications

Fast Facts Trinseo MAGNUM ABS Resins (Acrylonitrile Butadiene Styrene) for Medical Applications

Fast Facts Unique Advantages for the Medical Market As the demand for attractive medical equipment grows, manufacturers and molders are looking for housing and enclosure materials that provide aesthetic appeal and advanced performance. More than that, they need specific properties required by the medical industry such as biocompatibility, regulatory compliance and sterilization options. Trinseo s MAGNUM ABS Resins provide the assurance that stringent objectives will be met. Produced using mass polymerization techology, they are recognized as superior in areas such as automotive, consumer electronics and high end extrusion applications, and have has been relied on for decades to satisfy the critical needs of the most demanding applications. What is ABS? ABS is acrylonitrile butadiene styrene. The combination of these raw materials results in a materials that is durable and tough with nice aesthetics. It is ideal for a variety of opaque applications that range from large and small equipment housings to drug delivery devices, inhalers, insulin pens and nebulizers. The material can be fabricated in its natural color or with a colorant additive. It can host a range of performance properties, which are both intrinsic to the material or custom formulated. What are the advantages of Trinseo s ABS? Lower Residual Monomers Trinseo s continuous mass technology allows us to implement a cleaner, purer production process with little processing aids and additives. This reduces the likelihood of substance migration from the plastic and also reduces the risk when using Trinseo ABS in sensitive applications such as medical devices. Exceptional Stability The stability of our MAGNUM ABS means less property shift over time. This is critical for materials that are exposed to different environments, cleansers, and light sources allowing for a longer shelf life of finished products. Brilliant Whiteness, Superior Self-Coloring Trinseo s MAGNUM ABS resins have an exceptionally low base color resulting in a bright natural white. This allows lower pigment levels[or loading] for coloring and a rich, pure end result. The material is also ideal for self-coloring [masterbatching]. Versatility of Design With a high melt flow, Trinseo s MAGNUM ABS Resins provide product designers with a wide spectrum of design options. Besides MAGNUM ABS s best-in-class purity and cleanliness, Trinseo offers customized compounding services to meet our customers needs for material placement and functionality. Medical coloring, improved weatherability, anti-static, and laser-marking are examples of Trinseo s existing advanced compounding solutions. The material is also more thermally stable resulting in less color change at high temperatures for more flexibility in product design. Sterilization Options Medical devices made of MAGNUM ABS resins can be sterilized by gamma radiation, ethylene oxide (EtO) gas and electron beam radiation. Materials respond favorably maintaining essential properties.

Technology Comparison Mass Polymerization Technology vs. an Emulsion Process Monomer Rubber Solvent Monomer Water Emulsifier Monomer Salts Dissolve Devolatilize Rubber Reaction Graft Reaction Coagulation Antifoam ABS SAN Reaction ABS Compound Dewater & Dry Figure 1: Mass Polymerization Process With Trinseo s mass polymerization technology, MAGNUM ABS Resins are produced in a continuous process. This provides assurance of a homogeneous and consistent product. This process also uses very few process additives resulting in a clean, pure material that is essential in the medical market. ABS produced in the mass process is consistent and has low color. Figure 2: Emulsion Polymerization Process Traditional emulsion ABS technology uses a batch reaction process. This can result in variation among batches which can be problematic. This process requires many processing additives such as emulsifiers and coagulants. These impurities remain in the ABS at detectible levels. There are many processing steps involved in this process resulting in higher color. Chemical Resistance Consistent with acrylonitrile butadiene styrene (ABS), Trinseo s formulation of MAGNUM ABS is suitable for health care environments where the material is exposed to a wide variety of surface disinfectants and cleaners. The adjoining chart indicates resistance level: Chemical Good Fair Poor Alcohols Aldehydes Aliphatic Hydrocarbons Aromatic Hydrocarbons Dilute Acids Dilute Bases Esthers Isopropyl Alcohol (IPA) Polyglycols Salts Applications Diagnostics instruments Home healthcare housings Surgical (skin) stapler housings Pumps and oxygenators

Lower Residual Monomers Low Residual Monomer & Oligomer Level 2, Residual Monomer & Oligomer Level Residuals & Oligomer Levels [%] 1,75 1,5 1,25 1,,75,5,25, Residual Monomer & Oligomer Level Emulsion ABS (US), Colored Emulsion ABS (EU), Natural Emulsion ABS (EU), White MAGNUM TM 8391 MED Natural MAGNUM TM 8391 MED White 1,72 1,58 1,52,75,72 Figure 3: Residuals left after resins are produced using an emulsion process compared to those in MAGNUM with mass polymerization Trinseo s MAGNUM ABS Resins produced with our mass polymerization process results in lower residual volatiles remaining after the devolitilization process. The above chart compares the mass and emulsion processes for colored, natural and white resins and their residual monomers. Other Advantages Trinseo s MAGNUM ABS Resins are the resins of choice for critical engineering applications. Advantages include: Excellent processability = more parts per hour; wide processing window Superior practical toughness = better part performance Consistency in properties and performance = less down time; improved molded part consistency Superior natural resin whiteness = less pigment needed; less cost; true color Low levels of surface plate-out upon molding = minimizes machine downtime; improves final part aesthetics Ease of solvent and sonic bondability = faster, easier assembly Committed to the medical industry Trinseo offers a wide range of different materials for single and multiple use devices and equipment housings in the medical market. MAGNUM ABS MED Resins joined our portfolio following break-through developments of CALIBRE and CALIBRE MEGARAD Polycarbonate Resins and EMERGE Advanced Resins. STYRON Polystyrene Resins complete our portfolio for medical applications.

Important Advantages Base Color Base Color of MAGNUM ABS RESINS pigment levels for your desired sheet color. vs. Competitive Resins 35 1 Thermal Stability Color Shift of Oven-aged Plaques at 7 C Aging Temperature Yellowness Index 3 25 2 15 1 5 Color Shift [ E] 8 6 4 2 Emulsion ABS (APAC) Mass ABS MAGNUM TM ABS Based on Mass Technology Competitive Resins 5 1 15 2 25 Exposure Time [Days] Figure 1: Pure Base Color Trinseo s MAGNUM ABS resins have exceptionally low base color, allowing lower pigment levels for your desired item. Figure 2: Thermal Stability Trinseo s MAGNUM ABS resins provide among the best thermal characteristics in the industry, resulting in higher color stability. Result of Lot-to-Lot Variations in Natural Resin ( ) CMC Consistency Lot-to-Lot Consistency of ABS Resins vs. Competitive Resins 2. 1.5 1..5. VISIBILITY LIMIT MAGNUM TM ABS Based on Mass Technology Competitive Resins Color Shift [ E] 14 12 1 8 6 4 2 Color Shift Results from QUV-A (Indoor Exposure) 25 5 Time [Hours] 75 1 Emulsion ABS (EU) + 3% MB 744 (white) MAGNUM TM 8391 + 3% MB 744 (white) Figure 3: Consistency Trinseo s MAGNUM ABS resins have more consistent color, lot-to-lot and run after run. Figure 4: Color Shift Samples of MAGNUM ABS Resins and ABS produced using the traditional emulsion method were exposed in a UV-2 tester according to ASTM G154 indoor conditions. The chart above indicates that after 25 hours, color shifting increased dramatically with resins produced with emulsion polymerization vs. mass polymerization. Focused on Meeting Your Needs. Because Trinseo manufacturers a series of its MAGNUM ABS resins as medical grade polymers, they are designed to provide the biocompatibility, FDA compliance, sterilization options, and molding characteristics required by the medical industry. Extensive testing for biocompatibility has been conducted both by Trinseo and by independent laboratories. Results show these resins to be compatible with living systems. MAGNUM ABS Resins are designed for housing applications that require durability and pleasing aesthetics. Trinseo collaborates with customers so that materials selected meet the specific needs of each application, including property performance, part design/ manufacturing and regulatory requirements. MAGNUM ABS Resins are available in custom color opaques as well as glossy or matt finish. Contact Us. For more information on MAGNUM ABS MED Resins or other materials for medical equipment housings or to request a sample, contact us at CIG@trinseo.com.

For more information on products, innovations, expertise, and other services available from Trinseo, visit www.trinseo.com, or contact us as indicated below. The principles of Responsible Care and Sustainable Development influence the production of printed literature for Trinseo S.A. and its affiliated companies. As a contribution towards the protection of our environments, Trinseo s printed literature is produced in small quantities and on paper containing recovered/post-consumer fiber and using 1 percent soy-based ink whenever possible. PRODUCT STEWARDSHIP Trinseo and its affiliated companies have a fundamental concern for all who make, distribute, and use their products and for the environment in which we live. This concern is the basis for our Product Stewardship philosophy by which we assess the safety, health, and environmental information on our products so that appropriate steps may be taken to protect employee and public health and our environment. The success of our product stewardship program rests with each and every individual involved with Trinseo products from the initial concept and research, to manufacture, use, sale, disposal, and recycle of each product. CUSTOMER NOTICE Customers are responsible for reviewing their manufacturing processes and their applications of Trinseo products from the standpoint of human health and environmental quality to ensure that Trinseo products are not used in ways for which they are not suitable. Trinseo personnel are available to answer questions and to provide reasonable technical support. Trinseo product literature, including safety data sheets, should be consulted prior to the use of Trinseo products. Current safety data sheets are available from Trinseo. No freedom from infringement of any patent owned by Trinseo or others is to be inferred. Because use conditions and applicable laws may differ from one location to another and may change with time, the customer is responsible for determining whether products and the information in this document are appropriate for the customer s use and for ensuring that the customer s workplace and disposal practices are in compliance with applicable legal requirements. Although the information herein is provided in good faith and was believed to be accurate when prepared, Trinseo assumes no obligation or liability for the information in this document. NOTICE REGARDING MEDICAL APPLICATION RESTRICTIONS Trinseo requests that customers refer to Trinseo s Medical Application Policy http://www.trinseo.com/medical.htm before considering the use of Trinseo products in medical applications. The restrictions and disclaimers set forth in that policy are incorporated by reference. North America +1-855-TRINSEO (855-874-6736) Europe +31-115-67-261 South America Brazil +8-474714 Argentina +8-266569 Chile +123-2-1124 Colombia +18-5182475 Mexico +18-834913 Asia Pacific +6-3-7965-5319 China +86-21-3851-117 Email CIG@trinseo.com www.trinseo.com DISCLAIMER TRINSEO MAKES NO WARRANTIES, EITHER EXPRESS OR IMPLIED, IN THIS DOCUMENT; ALL IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE (INCLUDING MEDICAL APPLICATIONS) ARE EXPRESSLY EXCLUDED. TRINSEO DISCLAIMS ANY AND ALL LIABILITY FOR LOSSES OR DAMAGES THAT MAY RESULT FROM THE USE OF TRINSEO PRODUCTS IN UNSUPPORTED USE. TRINSEO MAKES NO WARRANTIES, EXPRESS OR IMPLIED, THAT THE USE OF ANY TRINSEO PRODUCT WILL BE FREE FROM ANY INFRINGEMENT CLAIMS. GENERAL NOTICE Any photographs of end-use applications in this document represent potential end-use applications but do not necessarily represent current commercial applications, nor do they represent an endorsement by Trinseo of the actual products. Further, these photographs are for illustration purposes only and do not reflect either an endorsement or sponsorship of any other manufacturer for a specific potential end-use product or application, or for Trinseo, or for specific products manufactured by Trinseo. If products are described as experimental or developmental : (1) product specifications may not be fully determined; (2) analysis of hazards and caution in handling and use are required; (3) there is greater potential for Trinseo to change specifications and/or discontinue production, and (4) although Trinseo may from time to time provide samples of such products, Trinseo is not obligated to supply or otherwise commercialize such products for any use or application whatsoever. For additional information not covered by the content of this document or to ensure you have the latest version of this document available, please refer to the Customer Information Group contact information on our website at www.trinseo.com/contact/. Copyright Trinseo (217) All rights reserved. Trademark of Trinseo S.A. or its affiliates Responsible Care is a service mark of the American Chemistry Council Form No. 859-11