MEDIA INFO. ltranskript. Special. European Biotechnology 31st Biotechnologie Das Jahr- und Adressbuch.

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Analytics ACHEMA 018 Special LABORWELT ltranskript www.european-biotechnology.com Cell analysis + Screening www.medtech-zwo.de Bio-Europe Diagnostics Financing CMOs, & CROs Bioprocess Digitalisation Pharmapack Europe MEDIA INFO CPhI Worldwide Analytica 018 Screening medtech zwo www.biotechnologie.de Events European Biotechnology 31st Biotechnologie Das Jahr- und Adressbuch Lab automation Costumer Identity/Access Management Bio-IT + Sequencing www.transkript.de www.laborwelt.de Biomanufacturing BIOCOM

Media Info 018 European Biotechnology Magazine reports in English on political, economic, and technical developments at the intersection of biotech, pharma, medtech, and chemistry in the 8 countries of the European Union, plus Switzerland and Norway. With a circulation of more than 13,000 copies, the journal provides a suitable platform for pan-european marketing campaigns that take advantage of the huge, common, economic area. Subscriptions 018: A nnual subscription companies/institutes 80 A nnual subscription students/unemployed people 40 European BiotechnoloNgeyws European hnology BiotecPublished: News Q uarterly, Subscription prices include VAT and delivery. stry Science & Indu Oct obe r 01 Selected media partners: ACHEMA, Analytica, BIOEurope, BioProcess International EU Summit, Berlin Conference in LS, BioFIT, Chemspec Europe, CPhI, DIA Meetings, EFIB, PharmaLab Congress, Pharmapack Europe, Swiss Biotech Day stry Science & Indu four issues per year Oct obe r 01 Volume: Volume 17, 018 ß"IOCAPITAL ))ß%UROPEAN European Biotechnology Magazine dates Issue Special Topics and Event Highlights CAPITAL Spring Featured topics: Bioprocessing + GMP Events: BIO-Europe Spring, Swiss Biotech Day, Achema Summer Event preview: Euro BioFairs Compass Autumn 018 ß"IO ))ß%UROPEAN Supplement Booking Publication SPECIAL 19.0.18 08.03.18 04.06.18 1.06.18 03.09.18 0.09.18 6.11.18 13.1.18 airs Euro BioFas Coomp s 0.10.01 18:16:56 Uhr September 01 d.indd ecial_titel_pa _Sp 35_EBSIN10_1 1 Autumn Featured topics: CMOs & CROs + Pharma Packaging Events: CPhI Worldwide and BIO-Europe Winter Event preview: Euro BioFairs Compass Winter/Spring + Packaging Special: Pharmapack Europe 019 _Sp d.indd ecial_titel_pa 35_EBSIN10_1 1 ))ßß'UIDEßTOß ß%VENTS,IFEß3CIENCES SPECIAL airs Euro BioFas Coomp s 0.10.01 18:16:56 Uhr SPECIAL September 01 ))ßß'UIDEßTOß ß%VENTS,IFEß3CIENCES You can expect these topics in every edition: SPECIAL Biomanufacturing Consumables Bioinformatics Biotech Diagnostics Health Economics VC Consulting Laboratory Equipment Pharmaceutical Reagents Industrial Biotech Bioplastics Intellectual Property Partnering CMO CRO Medical Devices Trade Shows Investment Antibodies Biomarkers Clinical Trials Biofuels Bioeconomy Politics Biopeople Start ups

ADVERTISING RATES 018: 1/1 page (4c).............. 3,000 1/ page (4c).............. 1,800 1/3 page (4c).............. 1,400 1/4 page (4c).............. 1,00 Product information........... 400 Special placement addition (e. g., cover pages).... 500 PARTNER ASSOCIATIONS European Biotechnology NETWORK COMPANY PROFILE/ ADVERTORIAL: 1/1 page advertorial/company profile (Headline, intro text, main text, and 1 image) 3,000 /1 page advertorial/company profile (Headline, intro text, main text, and images) 4,500 JOB OFFERS: 1/1 page b/w.............. 1,000 1/ page b/w.............. 500 1/4 page b/w.............. 50 @ SUPPLEMENTS: up to 5 g................ 3,000 up to 50 g............... 5,000 plus delivery charges Council of European BioRegions GEOGRAPHIC COVERAGE: Region.................... Copies Western Europe (GB, IRL, F, and BeNeLux) 4% 3,084 Central Europe (D, A, and CH)..... %,87 Southern Europe (P, E, I, GR, M, and CY) 1%,698 Northern Europe (S, FIN, DK, and NOR)..14% 1,799 Eastern Europe (PL, CZ, SK, HR, HUN, SLO, LIT, LET, and EST)...........10% 1,85 Other regions (USA, CDN, J, and AUS).. 9% 1,157 RECIPIENTS BY SECTOR: Industry.................. 80% Companies pharma / medicine / biotechnology 31% CRO & CMO / provider / supplier / laboratory 4% Industrial large-scale production / chemistry 18% Agriculture and food production.... 7% Research................. 15% Public law research institutes...... 9% Private industry research institutes... 6% CIRCULATION: Print run.................. 13,00 Actual circulated copies........... 1,850 Regular recipients / subscribers...... 8,10 received as part of membership package 5,560 received as single subscriptions.....,560 Free copies................. 4,730 complimentary copies for trade shows, events, media partners, etc......... 4,00 Other, archive, and author copies...... 350 Private industry / other......... 5% RECIPIENTS BY POSITION: Lab- / division- / unit leaders..... 3% Company- / operations management. 1% Politics / foreign trade / business development 0% Distribution / sales / marketing.... 15% R&D / education........... 10% Organisation / administration..... 8% Private subscribers / other...... 3% Contacts: Oliver Schnell, Andreas Macht, Christian Böhm Tel. +49 030 6491-45/-54/-49 E-Mail: marketing@biocom.de

THE INFORMATION PORTAL FOR THE EUROPEAN MARKET european-biotechnology.com Making the biotech scene accessible in Europe: that is the goal of European-Biotechnology.com! With reliable insider news and information from every bioregion on the continent, the European Biotechnology News portal is a key source for daily on Europe s biotech community. Andreas Macht Marketing Manager Whether it s an international marketing campaign or a European marketing event, our English-language portal offers you tailor-made solutions. 1 Leaderboard Medium Rectangle 3 Skyscraper Weekly enewsletter with up-to-date news and events as well as integrated online videos. Media Info 018 5 Premium Banner 4 advertorial 1 3 4 Leaderboard 1,500/week Medium Rectangle Skyscraper 1,000/week Advertorial 1,500/month 6+7 Video/ Produkt Anzeige 5 6 7 8 Premium Banner 600/week Video Ad (homepage + content*) Product Ad (homepage + content*) Standard Banner 300/week (rotation) 8 Standard Banner * Prices include permanent publication of content on the section pages.

Quick facts Visits: 14,750 monthly Pag eimp.:,500 monthly Users: 69% Europe % North America 7% Asia % Other +17,100 Newsletter subscribers (Statistics as of September 017) Users by sector groups 43% pharma / medicine / biotechnology 19% industrial scale production / chemistry 18% providers / IP & finance / suppliers / labs 15% research facilities (public/private) 5% agriculture and food production Newsletter subscribers by function 4% laboratory- / division- / department management 1% corporate- / operations management 0% politics / foreign trade / economic development 17% distribution / sales / marketing 11% R&D / education 5% organisation / administration / personnel % private / other enewsletter Frequency: weekly Subscribers: 17,100 (as of September 017) Banner: 300 per newsletter mailing Reporting Free reporting available after campaign completion Contacts: Oliver Schnell, Andreas Macht, Christian Böhm Tel. +49 030 6491-45/-54/-49 E-Mail: marketing@biocom.de

Media Info 018 Every month, for the last 4 years, transkript has reported on biotechnology in German-speaking Europe. With coverage on the latest news in economy, finance, research, and politics, the publication also offers application-oriented articles on science, technology, and finance. Each edition contains a supplement with a unique, featured topic, five of which are LABORWELT specials. Subscription prices 018: Annual subscription for companies/institutions 186 Annual subscription for individuals 94 Annual subscription for students/unemployed people 48 Subscription prices incl. VAT and delivery. Published: Monthly, with two doubleissues per year Volume: Volume 4, 018 Cooperation Partners: Deutsche Gesellschaft für Proteomforschung (DGPF), BIO Deutschland e. V., Fachabteilung Life Science Research (LSR) im VDGH, Biotechnologische Studenteninitiative bts e. V. transkript dates Issue Special Topics and Event Highlights Supplement Booking Publication 1/ Digitalisation of Life Sciences: Customer Identity + Access Management Bio-IT + Sequencing 19.01.18 01.0.18 3 LABORWELT Special: Cell Analysis / Screening 1.0.18 01.03.18 4 LABORWELT Special: Analytica Fair 018 1.03.18 9.03.18 5 Featured Topic: BIO Convention USA 018 + Distribution of the englisch language Special at the event 19.04.18 03.05.18 6 ACHEMA 018 + Chemspec Europe 018 14.05.18 31.05.18 7/8 LABORWELT Special: Lab Automation 18.06.18 05.07.18 9 Biomanufacturing + Packaging 13.08.18 30.08.18 10 LABORWELT Special: Diagnostics 17.09.18 04.10.18 11 Featured Topic: Finance, BIO-Europe 15.10.18 01.11.18 1 LABORWELT Special: Analytics Eventpreview 019 1.11.18 9.11.18

> 50% of our readers are decision makers! Advertising rate 018: 1/1 page (4c).............. 3,000 1/ page (4c).............. 1,800 1/3 page (4c).............. 1,400 1/4 page (4c).............. 1,00 Product information........... 50 Special placement addition (e. g., cover pages).... 500 company profile: 1/1 page advertorial/company profile (Headline, intro text, main text, and 1 image) 3,000 /1 page advertorial/company profile (Headline, intro text, main text, and images) 4,500 Job Offers: 1/1 page b/w.............. 1,000 1/ page b/w.............. 500 1/4 page b/w.............. 50 Special placement addition (e.g., cover pages)... 500 inserts: -page............. Prices on request 4-page................. 3,000 Supplements: Up to 5 g...............,000 Up to 50 g............... 3,500 plus delivery charges No 1 >90% of Germany s Biotech firms read transkript* * according to survey by BIO Deutschland e.v. in 017 Geographic Coverage: Region.................. Copies Germany.............. 65% 6,77 Switzerland............. 18% 1,863 Austria................ 15% 1,553 Other................ % 07 circulation: Print run.................. 10,500 Actual circulated copies........... 10,350 Copies sold................ 5,05 copies subscribed........... 3,40 received as part of a membership package 1,605 Complimentary copies............ 5,35 delivered to trade shows, congresses, cooperating companies / institutions... 4,880 Other, archive, and author copies...... 150 recipients by sector: Industry.................. 71% Companies pharma / medicine / biotechnology 9% CRO & CMO / provider / financers / supplier / labs 4% Industrial large-scale production / chemistry 14% Agriculture and food production..... 4% Research................. 7% Public law research institutes...... 16% Private industry research institutes... 11% Private industry / other......... % Recipients by position: Lab- / division- / unit leaders..... 9% Company-/ operations management.. 5% R&D / education........... 17% Distribution / sales / marketing..... 16% Organisation / administration / personnel 9% Private subscribers / other....... 4% Kontakte: Contacts: Oliver Schnell, Andreas Macht, Christian Böhm Tel. +49 030 6491-45/-54/-49 E-Mail: marketing@biocom.de

THE ONLINE NEWS PORTAL WITH DAILY UPDATES transkript.de Check out the latest news from the life sciences sector as you have your morning coffee! Filled with the latest business and science news, insider details, the latest technologies and devices, and an events calendar covering highlights in the biotech scene, transkript.de is the essential daily online portal for decision makers in the German-speaking industry. Oliver Schnell Head of Marketing transkript.de updated daily, with informative, broad coverage your portal for measurable success. 1 Leaderboard Weekly enewsletter with current news, personal profiles, and an events calendar. 6 Medium Rectangle 3 Skyscraper Media Info 018 4 Premium Banner Advertorial 1 3 4 Leaderboard 1,500/week Advertorial 1,500/month Skyscraper 1,000/week Premium Banner 600/week 5+7 Produkt/ Video Anzeige 8 Standard Banner 5 6 7 8 Product Ad (homepage + content*) Medium Rectangle Video Ad (homepage + content*) Standard Banner 300/week (rotation) * Prices include permanent publication of content on the section pages.

Quick facts Visits: 1,850 monthly Pag eimp.: 38,90 monthly UserS: 70% Germany 15% Austria 13% Switzerland % Other (Statistics as of September 017) Users by sector groups 33% pharma / medicine / biotechnology 5% CMOs / providers / suppliers / laboratory 18% research facilities (public/private) 17% industrial scale production / chemistry 7% agriculture and food production Newsletter subscribers by function 30% laboratory- / division- / department management 3% corporate- / operations management 18% politics / foreign trade / economic development 1% R&D / education 10% distribution / sales / marketing 5% organisation / administration / personnel % private / other enewsletter Frequency: weekly Subscribers: 14,810 (as of September 017) Banner: 300 per newsletter mailing Reporting Free reporting available after campaign completion Contacts: Oliver Schnell, Andreas Macht, Christian Böhm Tel. +49 030 6491-45/-54/-49 E-Mail: marketing@biocom.de

THE NEXT GENERATION OF DIGITAL LAB NEWS laborwelt.de This is where decision makers, as well as those at the bench, go to find out about recent trends and products. Our website, laborwelt.de, is the perfect combination of information and day-to-day entertainment for anyone involved in the lab. Packed full of interesting news and expert articles, videos, picture galleries, and subject dossiers, as well as the latest methods and devices, we cover the spectrum of the life sciences community. 1 Leaderboard Christian Böhm Marketing Manager Whether it s an event, product, or white paper, you can advertise on the site for all things labrelated. The additional weekly enewsletter provides information on current lab news, interesting videos, and the latest trends from the world of science. 6 Medium Rectangle 3 Skyscraper Media Info 018 4 Premium Banner Advertorial 1 3 4 Leaderboard 1,500/week Advertorial 1,500/month Skyscraper 1,000/week Premium Banner 600/week 5+7 Produkt/ Video Anzeige 5 6 7 8 Product Ad (homepage + content*) Medium Rectangle Video Ad (homepage + content*) Standard Banner 300/week (Rotation) 8 Standard Banner * Prices include permanent publication of content on the section pages.

Quick facts Visits: 18,80 monthly Pag eimp.: 3,550 monthly UserS: 75% Germany 75% 14% Switzerland 11% Austria 1% Other 14% 10% (Statistics as of September 017) Users by sector groups 35% pharma / medicine / biotechnology 33% service providers / suppliers / laboratory 14% research facilities (public/private) 1% industrial scale production / chemistry 6% agriculture and food production Newsletter subscribers by function 30% R&D / education 6% laboratory- / division-/ department management 3% corporate- / operations management 18% distribution / sales / marketing 3% private / other enewsletter Frequency: weekly Subscribers: 14,55 (as of September 017) Banner: 300 per newsletter mailing Reporting Free reporting available after campaign completion Contacts: Oliver Schnell, Andreas Macht, Christian Böhm Tel. +49 030 6491-45/-54/-49 E-Mail: marketing@biocom.de

Media Info 018 medtech zwo magazine The journal complements the successful online portal medtech-zwo.de with in-depth information. The focus is on innovative breakthroughs in medical technology, which help the healthcare industry in Germany, Austria and Switzerland. In addition to this, background reports from business, politics and technology, interviews and practical information on the trade fairs and congresses, in which the magazine appears twice a year. Advertising rates: 1/1 page (4c).............. 3,000 1/ page (4c)............... 1,800 1/3 page (4c)............... 1,400 1/4 page (4c)............... 1,00 Product information................ 300 Surcharge for special placements (e.g. cover pages)................ 500 Discounts for multiple order on request. FIRM PROFILE / PICTURE GALERY 1/1 page advertorial / company profile..... 3,000 /1 page advertorial / company profile..... 4,500 /1 page product galery....... price on request Published: half-yearly, issues per year medtech zwo magazine dates and breakdown: 1/18 Topics and events Medtec Europe, MT-Connect + conhit Issue Booking Publication 14.03.18 9.03.18 /18 Medica/Compamed 15.10.18 1.11.18 Ta rge t g r o u p: Medtech companies and suppliers, consultants and lawyers, capital & financing, policy, engineers and technicians Circulation Print: Print run.................. 16,000 Free copies / trade fair copies....... 10.10 Remainder, archive and sample copies... 5.470 Other, archive, and author copies...... 410 Geographic coverage: Germany: 76%, Austria: 14%, Switzerland: 10% Digital Version: Download via medtech-zwo.de and the weekly newsletter + mobile app Recipients by segment: Industry.................... 84% Medtech / Pharma companies......... 46% Suppliers / Service / Health IT / Lab...... 5% Healthcare (hospitals, health insurance)..... 8% Capital & financing............... 5% Other...................... 16% Research institutions (public / private)..... 6% Consulting & Law................ 5% Associations & Policy.............. 3% Other...................... % Recipient by function: Company / plant management....... 34% Department / division management..... 5% Sales / Distribution / Marketing....... 18% Development Department / IT & Technology 11% Research / Development / Teaching.... 8% Organisation / Administration / Personnel.. 4% Contact: Marco Fegers Tel. +49 030 6491-56 Email: m.fegers@biocom.de

medtech zwo Topics magazine 1 current Distribution partners* 1. Digitalisation of production: Manufacturing facilities, distributed control systems, automation, engineer to order, process control, realtime processing, process efficiency, manufacturing IT/ monitoring/maintenance, cloud computing, sensors, actuators, data standardisation and interfaces. Blockchains in medical technology: IT interfaces, cyber security, electronic patient record, audits, big data, mobile health 3. Medical devices regulation: Regulatory affairs consulting, clinical evaluation/clinical trials, CRO/CMO, UDI, post market surveillance, M&A, funding, licensing, outsourcing 4. New materials for medical devices: Plastics, ceramics, metals, composite material, biodegradables/bioresorbables, hydrogels, silicone, titanium, steel, compounds, raw materials & processing, additives, coatings/topical treatment and more! and more topics in the magazine preview Magazine /018: Announcements of topics as of 05/18 * subject to alterations supplements: up to 5 g................,000 up to 50 g............... 3,500 each plus postage cooperation partners Partner Publication registration possible all year! Enhancing Health Contact: Marco Fegers Tel. +49 030 6491-56 Email: m.fegers@biocom.de

The Web Portal For the Medical Technology INDUSTRY In GERMANY medtech-zwo.de Our website medtech-zwo.de puts the spotlight on medical technology s hidden champions. Here, you can find substantial financing rounds, strategic distribution agreements, and even the acquisition of the year with reports several times a week on economic issues in politics, education, and science-related, medical technology. Marco Fegers Marketing Manager "medtech-zwo.de: the news portal for the high-tech medical sector advertise here in proximity to your customers. 1 Leaderboard 6 Medium Rectangle 3 Skyscraper NEW: Your company news and press releases at medtech-zwo for 690 p.a. only! Media Info 018 4 Premium Banner advertorial 1 3 4 5 Leaderboard 1,500/week White Paper/ Advertorial 1,500/month Skyscraper 1,000/week Premium Banner 600/week Product Ad (homepage + content*) 5+7 produkt/ video anzeige 8 Standard Banner 6 7 8 Medium Rectangle Video Ad (homepage + content*) Standard Banner 300/week (rotation) * Prices include permanent publication of content on the section pages.

Quick facts Visits: 9,138 monthly Pag eimp.: 19,75 monthly Users: 77% Germany 77% 10% Switzerland 8% Austria 5% Other 10% 8% (Statistics as of September 017) Users by sector groups 4% companies medtech / pharma 1% suppliers / service providers / laboratory 10% capital & financing 9% healthcare sector (clinics, doctors, health insurance) 8% research facilities (public/private) 6% consulting & legal 3% associations & policies 1% other Newsletter subscribers by function 48% companies medtech / pharma 15% suppliers / service providers / laboratory 10% capital & financing 9% healthcare sector (clinics, doctors, health insurance companies) 6% research facilities (public/private) 6% consulting & legal 4% associations & policies % other According to function 3% corporate & facility management 3% sector & department management 16% distribution / sales / marketing 13% research / development / training / IT 11% organisation / administration / personnel 5% other enewsletter Frequency: weekly Subscribers:,750 (as of September 017) Banner: 300 per newsletter mailing Reporting Free reporting available after campaign completion Contacts: Marco Fegers, Andreas Macht Tel. +49 030 6491-56/-54 E-Mail: marketing@biocom.de

Media Info 018 For three decades, the german-language "BioTechnologie Jahr- und Adressbuch" has been the standard reference and business directory for the biotech industry in Germany, Austria and Switzerland. In its 30th year, the yearbook got a new and modern concept: current facts & figures reports and opinions on the development of the life sciences industries innovative technologies products & people backgrounds, financing, comments and much more. Special attention will be devoted to the new edition the ideal environment for your advertising. Retail price 018: Copy price 30 Retail price incl. VAT and shipping Publication date: 0 June 018 Booking deadline: 18 May 018 Publication frequency: Yearly Volume: 31st edition 018 Format NEW: 10 x 75 mm Language: German Advertising rates 018: 1/1 page (4c)................ 4,00 1/ page (4c)................,600 1/3 page (4c)................ 1,900 Surcharge for special placements (e.g. cover pages)... 500 COMPANY ADVERTORIAL: 1/1 page advertorial / guest contribution (maximum 4,000 characters + 1 picture)... 4,00 /1 page advertorial / guest contribution (maximum 8,000 characters + pictures).. 6,000 SERVICE PROFILE: 1/3 page 4c, landscape, incl. design / layout 400 Short text with company description, logo, photo of CEO/management and contact details SPECIAL ADVERTISING FORMATS: Inserts, bound inserts, banderoles etc... on request Circulation: Print run.............. min. 10,000 copies DISTRIBUTION: Sent to all subscribers of the business magazine transkript as well as decision-makers in business, research and policy Full-year, targeted distribution at trade fairs and congresses for the biotech / pharma / finance community Distribution via book retail and online TARGET GROUP: Biotechnology sector: R&D companies (both listed and unlisted) as well as suppliers in the areas of life sciences and biopharma in the DACH region Finance: Investors, analysts, investment bankers, corporate and tax advisors, law firms Business development: cluster management and bioregions, business plan and start-up competitions Patent: Lawyers, national and international law firms, industrial insurers Contact: Oliver Schnell, Andreas Macht, Christian Böhm Tel. +49 030 6491-45/-54/-49 E-Mail: marketing@biocom.de

Contacts: Andreas Macht Business Economist Sales & Marketing Oliver Schnell Business Economist Head of Marketing Christian Böhm Business Graduate Sales & Marketing Marco Fegers Sales & Marketing Tel.: +49-30-6491-54 a.macht@biocom.de Tel.: +49-30-6491-45 o.schnell@biocom.de Tel.: +49-30-6491-49 c.boehm@biocom.de Tel.: +49-30-6491-56 m.fegers@biocom.de BIOCOM AG has been tracking the development of biotechnology, life sciences, bioeconomy, and medtech in Germany and all across Europe for over 30 years. Content-driven and success-orientated, enthusiastic about the subject and always committed to the customer: that s the way we present our top end magazines and digital news portals, as well as the valid results generated throughout our consulting and project management divisions. BIOCOM