PRE-FEASIBILITY REPORT FOR PROPOSED API INTERMEDIATE MANUFACTURING OF GALAXY LABORATORIES PRIVATE LIMITED

Galaxy Laboratories Pvt. Ltd, an intermediate manufacturing unit for API and PRE-FEASIBILITY REPORT FOR PROPOSED API INTERMEDIATE MANUFACTURING OF GALAXY LABORATORIES PRIVATE LIMITED At Plot No. B-10, MIDC Newasa Industrial Area, at Post Tukai Shingve, Auranagabad Pune Highway, Near Godegaon, Tal. Newasa, Ahmednagar 414607 (Maharashtra)

CHAPTER 1 EXECUTIVE SUMMARY Galaxy Laboratories is a venture capital company promoted with equity participation from Industrial Development Bank of India (IDBI) in the year 1995. The company is a manufacturer of Intermediates for API s (Active Pharmaceutical Ingredients) and specialty Agro Chemicals. Galaxy is one of the leading manufacturers of the product Furfurylamine in the world. Furfurylamine is used in an API known as Furosemide which is primarily used for the treatment of hypertension, congestive heart failure and edema. Besides the domestic API s intermediates and Agro Chemicals market, it has a foreign customer base in Belgium, Germany, Israel, Japan, Italy and Korea. It has created a name for itself in the area of Catalytic Hydrogenation and Fractional Distillation. One of existing manufacturing facility is located at Railway Station MIDC Aurangabad, Maharashtra. The land area is 8158 sq. meters and the company has put up excellent manufacturing facilities as per international standards and complies with the prevailing GMP norms of MNC s. The turnover of the financial year 2013-14 was 29 Crores. The manufacturing Facilities are Multipurpose and versatile to handle advance technologies for manufacturing API Intermediates and specialized Agro Chemicals. NAME OF THE PROMOTERS AND THEIR TRACK RECORD : Sr. Name No. 1. Shrikant Deshmukh Age (yrs) Total Experience Educational Qualifications 60 36 years B Tech. (Pharmaceuticals & Fine Chemicals), UDCT, Mumbai. Experience in Brief Worked with multinational companies viz. Hoechst (Sanofi - Aventis), Roche Products Ltd., and Boehringer-Knoll at various levels.

2. Nagesh Walimbe 60 36 years Chemical Engineer from Indian Institute of Technology, Mumbai (I.I.T.) Prior to Galaxy Laboratories, copromoter of Ariane Orgachem Pvt. Ltd. (Now AMRI India Ltd.) engaged in manufacturing of APIs. He has worked with Multinational Companies namely Hoechst India Limited, Gharda Chemicals Ltd, Lupin Laboratories & Standard Organics Ltd in varied Capacities at Design & Management levels in India and abroad. He is running his own consultancy firm namely Zen Chemiconsultech Pvt. Ltd., Hyderabad. Galalxy is proposing new unit at Newasa MIDC with latest technology as per the GMP for producing the critical intermediates for API, Agro Products and Specialty Chemicals. The products are Hydrogen Gas, Furfuraldehyde, Furfuryl Alcohol, Mono IsoPropyl Amine, Di Methyl Amine Hydrochloride, Furfurylamine, 6-Chloro-5(2,3 Dichlorophenoxy) -2- Methylthio 1H, Benzimidazole (Triclabendazole Crude), 5-Chloro-4-Amino-2,1,3- Benzothiadiazole (TNZ), 2-Furoic Acid, Cyclohexenyl Ethyl Amine (CHEA). The company is also putting up Agro Research Centre herewith well-equipped and designed Research & Development Laboratory for API Intermediates. The proposed project comes under 5(f) of the schedule in EIA notification 2006. Thus environmental clearance is required for the said project. Particulars and details about the proposed project are given in following table

Particulars Name of the project Site Area Water requirement Power requirement Fuel requirement DG Set Details Proposed API Intermediate manufacturing unit at Plot No. B10, MIDC Newasa industrial area At Post. Tukai - Shingve, Taluka. Newasa Dist. Ahmednagar. B-10, Tukai-Shingve,Tal. Newasa, Dist. Ahmednagar 48400 sqm 84 m 3 /day 320 KVA 750 TPA 320 KVA Man Power 350 Project cost 1430 Lacs

CHAPTER 2 INTRODUCTION OF THE PROJECT 2.1 IDENTIFICATION OF PROJECT AND PROJECT PROPONENT Galaxy Laboratories Private Limited an API Intermediate manufacturing unit is proposed at Newasa MIDC on Pune- Aurangabad highway in Maharashtra. The company is a manufacturer of Intermediates for API s (Active Pharmaceutical Ingredients) and Specialty Agro Chemicals. PROPOSED PRODUCTS The proposed Unit at Newasa is comprised of manufacturing 10 different products. The details of products and the reasons for manufacturing are given in Table No 2.1. Table No2.1 Sr. No Product Name CAS No. Capacity (per annum) Reason for identification/ End use of Product 1 Hydrogen Gas 1333-74-0 18.72 Lacs NM 3 (250 NM 3 /Hr) Key raw material for pharmaceutical, chemical, agricultural, food, and allied industries. Used increasingly for its property of making the chemical processes pollution free. 2 Furfuraldehyde 98-01-1 600 Tons Key raw material in manufacturing of Furfurylamine and Furfuryl alcohol and 2-Furoic Acid. The main outlet of furfural is that it is a unique chemical feed stock for other furan derivatives. Furfural is effective as a solvent in phenolic resins and a wetting agent. In the manufacture of abrasive wheels, brake linings, and refractory products for steel

industry. Refining of lubrication oils and decolorizing agent (Oil Industry). 3 Furfuryl Alcohol 98-00-0 360 Tons Chemical building block for drug synthesis. 4 Mono Iso Propyl Amine 5 Di Methyl Amine Hydrochloride Furfuryl alcohol plays a vital role in the production of foundry sand binders. It is extensively used to produce cores and molds for metal casting. Wood modification. Corrosion resistant for cement, mortars and fiber-reinforced plastics. 75-31-0 120 Tons Glyphosate herbicide formulations. Regulating agent for plastic. Intermediate in organic synthesis of coating materials, plastics, pesticides, rubber chemicals, pharmaceuticals and others. Used an additive in petroleum industry. 506-59-2 1200 Tons Di Methyl Amine Hydrochloride is used in an API drug named Metformin. Metformin is an oral andiabetic drug. Metformin works by suppressing glucose production by the liver. 6 Furfurylamine 617-89-0 240 Tons Used as a key raw material for Furosemide (API Drug), this is primarily used for the treatment of hypertension, kidney stone, congestive heart failure and edema. It has a new application in agro products. 7 6-Chloro-5(2,3 68786-66- 100 Tons Triclabendazole (N-1) is used

Dichlorophenox y)-2-methylthio 1H Benzimidazole (Triclabendazol e Crude) 8 5-Chloro-4- Amino-2,1,3- Benzothiadiazol e (TNZ) 3 in a drug named Triclabendazole which is developed as an oral route drug, and displays high efficacy against both immature and adult liver flukes, roundworms and ectoparasites. 30536-19- 7 9 2-Furoic Acid 29447-28- 9 10 Cyclohexenyl Ethyl Amine (CHEA) It is also used as a veterinary drug. 24 Tons 5-Chloro-4-Amino-2,1,3- Benzothiadiazole is used in an API drug called Tizanidine, which is a short-acting muscle relaxant. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone. 60 Tons 2-Furoic acid helps sterilize and pasteurize many foods. 2-Furoic acid is used as an intermediate in a drug named Quinfamide. Quinfamide is a drug that has anit-parasitic properties. It is used to treat chronic and sub-acute intestinal amebiasis. 2-Furoic Acid is used as speciality chemical in allied industries. 3399-73-3 120 Tons CHEA is used as an intermediate for the drug named dextromethorphan which is used for treating cough. PROJECT PROPONENT Galaxy Laboratories is a venture capital company promoted with equity participation from Industrial Development Bank of India (IDBI) in the year 1995. The company is a manufacturer of Intermediates for API s (Active Pharmaceutical Ingredients) and specialty Agro Chemicals. It is one of the leading manufacturers of the product Furfurylamine in the

world. Furfurylamine is used in an API known as Furosemide which is primarily used for the treatment of hypertension, congestive heart failure and edema. Galaxy promoted by Shrikant Deshmukh and Nagesh Walimbe both are having 36 years of experience in chemical units worked with multinational companies. Hoechst India Ltd., Roche products Ltd. etc. 2.2 BRIEF DESCRIPTION OF NATURE OF THE PROJECT The proposed Unit at Newasa aims at commercialization of ingeniously developed technology from Agro based in the area of Furfural chemistry and value-added derivatives of Furfural namely Furfuryl Alcohol and Furfurylamine. Galaxy has also proposed commercial processes for API Intermediates. These technologies are mainly in the area of reductive Amination by hydrogenation, catalytic hydrogenation with selectivity and isomerization. The company is also setting up a Hydrogen Plant for the generation of in-house hydrogen gas. Further, the company is adept at handling Hydrogen gas, Raney Nickel, Palladium- Carbon, Platinum and other noble metal catalysts, as also in hazardous chemicals like Carbon Di Sulphide, Fuming Nitric Acid, Thionyl Chloride, Phosphorous Oxychloride, Liquid Ammonia etc. 2.3 NEED FOR THE PROJECT AND ITS IMPORTANCE TO THE COUNTRY OR REGION The products proposed to be manufactured by the company are a new generation product range based on Reductive Amination by Hydrogenation, these are high value intermediates involving Hydrogenation Technology and compounds require Ring Hydrogenation for the manufacture lifesaving API s. The products developed by Galaxy are substantially of low prize compared to imported material. This is due to much less consumption of Raw Materials, Less number of Chemical steps involved in Manufacturing & being Green Technology. Products viz 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole Crude), 5-Chloro-4-Amino-2,1,3- Benzothiadiazole, 2-Furoic Acid proposed to manufactured in the project have huge export potential and contribute highly in import substitution for the country. Hydrogen gas manufacturing will reduce import of hydrogen gas from China and Germany. At present procurement of hydrogen gas is been done from outside of Maharashtra for our Aurangabad plant. Due to establishment of Indian made hydrogen plant with M/s Muse Consultants & Multifab Engineers (Mumbai) will be the first of its kind to be set up in Newasa. Hydrogen gas will be available for captive consumption and also support/supply other industries which have requirement for the same. Through this venture, India can establish its name in the foreign market.

Manufacturing of Furfuraldehyde, furfural alcohol and furfuryl amine in India will considerably reduce imports from International markets. The country will be self reliant and also reducing dependability of Indian API and allied manufacturers on International market. Hence the outflow of foreign exchange will be limited. Galaxy is the only company who has successfully introduced Furfurylamine in India and has become one of world s largest manufacturer. Recent research has developed some high value agro-products using 3-Hydroxy Pyridine and 2-Chloro-3-Hydroxy Pyridine as basic raw materials. These two products are synthesized from Furfurylamine; therefore demand for Furfurylamine is growing disproportionately. Production of Mono Iso Propyl Amine (MIPA), Di Methyl Amine Hydrochloride (DMA.Hcl), Cyclohexenyl Ethyl Amine (CHEA) will be profitable due to high tonnage production and no dependability on petroleum products and in-house availability of hydrogen gas. These API intermediates have very high potential because API s made out of the intermediates have come out of patent regulations in the international market since 2009. Therefore, Indian MNC s are launching these API s, as a result, consumption of these intermediates have increased rapidly. Thus the setting up of proposed API unit at Newasa will contribute in economic growth of India as well as region by increasing exports and limiting imports of material / chemicals. At the same raising self reliance of the country on these products. 2.4 DEMAND-SUPPLY GAP Demand-Supply Gap for Furfuraldehyde, Furfuryl Alcohol and Furfurylamine, Hydrogen gas The information given for the three products mentioned below is related to World Demand- Supply gap.

Furfuraldehyde Furfuryl Alcohol World Demand for Furfuryl Alcohol (TPA) World Supply for Furfuryl Alcohol (TPA) 6% 2% 8% 2% 5% 3% 4% 13% 4% 53% China USA India 9% 5% 34% 52% China Thailand USA India

Furfurylamine Hydrogen Gas Hydrogen gas will not be exported. There is a huge demand for Hydrogen gas in the domestic market and Galaxy will majorly consume it captively. The below mentioned information is based on demand-supply gap for Hydrogen Gas in domestic market (India).

Mono Iso Propyl Amine (MIPA) For explaining the demand-supply gap, export demand has not been taken into consideration, as the entire capacity is already being required by our current customers. Supply: Sources majorly imported Manufactured in India in unorganized sector Di Methyl Amine Hydrochloride (DMA.HCl) Supply Imported from China

Small Manufacturers In-house production by API Companies Cyclohexenyl Ethyl Amine (CHEA) Supply Imported from China Small Manufacturers in India 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole Crude)

Supply Imported from China Small Manufacturers in India Currently the major supplier is Galaxy for domestic market. 5-Chloro-4-Amino-2,1,3- Benzothiadiazole (TNZ) Demand for TNZ (TPA) 10% 10% 38% Dr. Reddy's Laboratories (Hyderabad) Med Concepta 28% 14% Sun Pharma (Baroda) 2-Furioc Acid

2.5 IMPORTS VS. INDIGENOUS PRODUCTION SR. NO. PRODUCT IMPORT INDIGENOUS 1 Hydrogen Gas (Hydrogen Plant) Currently hydrogen plant is imported from Germany or China. Galaxy along with Muse Consultants is venturing into setting up the first Indian made Hydrogen plant. This will give the country prestige and importance to erect further more hydrogen plants in the near future at a low cost compared to that of the foreign countries. 2 Furfuraldehyde The current unorganized sectors of manufacturers in India are not able to fulfill the requirement of Furfural. Lot of Furfural is required to produce Furfural related derivatives and therefore it is imported from China & Thailand. 3 Furfuryl Alcohol Furfuryl Alcohol is currently manufactured mostly in China. 4 Mono Iso Propyl Amine Currently MIPA is being imported in India by companies like IPCA Laboratories Pvt. Ltd. Galaxy plans to make tie ups with farmers producing corn, in and around Newasa area and will produce Furfural in huge quantity for meeting the requirements of manufacturers who focus on value added derivatives of Furfural. As this is an important chemical for many industries other than Pharmaceuticals, manufacturing in India will open a new export market and will meet indigenous requirement. Indigenous production of MIPA will promote exports and is helpful to many industries as it has multiple properties and used in varied industries. 5 Di methyl amine hydrochloride Di methyl amine is being imported in India from China. This is used as an important raw material for manufacturing an important API drug known as Metformin. Indigenous manufacturing of this drug will help Indian based API MNC S in sourcing this raw material from

Galaxy rather than importing it. 6 Furfurylamine Other than Galaxy there is only one company called PENN Specialty in the U.S.A. that manufacture Furfurylamine. Galaxy is the only manufacturer in India that manufactures Furfurylamine and supplies it to API companies like IPCA Laboratories, Amri India, Hemdeep and Sri Krishna Laboratories. This material is also exported to Sanofi Aventis (Germany), Teva Tech (Israel), Syngenta (USA), and Sojitz (Japan). 7 6-Chloro-5(2,3 Dichlorophenoxy)-2- Methylthio 1H Benzimidazole (Triclabendazole Crude) 8 5-Chloro-4-Amino- 2,1,3- Benzothiadiazole 9 2-Furoic Acid 10 Cyclohexenyl Ethyl Amine (CHEA) These raw materials were imported from South East Asian countries like China, Thailand etc. Galaxy Supplies these key raw materials to company s like: NGL Pharma Laboratories Sequent Scientific Ltd. Dr. Reddy s Laboratories Sun Pharma Med Concepta Survival Technologies Wokhardt Limited Galaxy has facilitated the supplies of these MNC s to provide key raw materials for API drugs. 2.6 EXPORT POSSIBILITY All the products have potential of being exported as there has been a very niche segment of manufacturers in India that manufacture these above mentioned molecules and Galaxy s share in the supply is a major one. These products are in high demand for API MNC S established in India and abroad. Galaxy has established its name in the API Intermediate market and has been an approved vendor for many MNC S. When developing a new product, the company can leverage the brand to market the products and can sell these products in the export market.

2.7 DOMESTIC/EXPORT MARKETS Already discussed in section 2.5 and 2.6 2.8 EMPLOYMENT GENERATION (DIRECT/INDIRECT) DUE TO THE PROJECT The local areas will be benefited by way of generation of employment opportunities, increased demand for local products and services. There will be an overall improvement in the income level of the people. The project creates employment to about 350 persons once the plant comes to the operational stage and for 150 persons during construction stage. Top priority will be given to locals for semi-skilled and unskilled jobs. With the development of this plant there will be a lot of scope for more ancillary development, which in turn will benefit the nation. There will be a certain enhancement of educational and medical standards of people in the study area. There will be generally positive and beneficial impacts by way of economic improvements, transportation, aesthetic environment and business generation. There will be an overall upliftment of socio-economic status of the people in the area with the implementation of the project. Manufacturing of furfural requires corncobs in high tonnage which can be achieved by providing the local farmers with seeds which will directly benefit the farmers in terms of agriculture and the company for meeting its raw material needs. Biomass generated in this product is of good fuel value and can be directly used as boiler fuel. Agriculture Cooperative Society will be formed, wherein the farmers will be benefited and there will be growth in agriculture.

CHAPTER 3 PROJECT DESCRIPTION 3.1 TYPE OF PROJECT INCLUDING INTERLINKED AND INTERDEPENDENT PROJECTS 3.1.1 Type of Project Galaxy Laboratories Private Limited is mainly engaged in manufacturing of API Intermediates and Agro-Chemicals. The company in the proposed project aims at commercialization of indigenously developed technology from Agro based in the area of Furfural chemistry and value-added derivatives of Furfural namely Furfuryl Alcohol and Furfurylamine. The company is setting up a Hydrogen Plant for the generation of inhouse hydrogen gas. 3.1.2 Interlinked and Interdependent Projects One of the products Furfuraldehyde requires agro waste (corncob) as raw material. Galaxy aims at making tie-ups with farmers in proximity with the Newasa for the cultivation of corn. This will benefit the farmers as corn cultivation is pre-dominant in Aurangabad district. Thus, the farmers and the company will be interdependent and will benefited. The Hydrogen plant being set-up at Newasa is the first Indian made Hydrogen plant. Which is a raw material for Furfuryl alcohol, Furfuryl amine, CEA, CAB,MIA, 3.2 Location The proposed chemical plant is located Plot No. B-10, MIDC Newasa Industrial Area, at Post Tukai Shingve, Auranagabad Pune Highway, Near Godegaon, Tal.Newasa, Ahmednagar 414607 (Maharashtra). The latitude and longitude are 19 0 18 20.12 N, 74 0 51 18.38 to 19 0 18 23.36 N, 74 0 51 09.69 E respectively.

Fig 3.1 Google image of Location 3.3 DETAILS OF ALTERNATE SITES CONSIDERED AND THE BASIS OF SELECTING THE PROPOSED SITE: 3.3.1 Alternate Sites API intermediate unit can be set-up in industrial areas and therefore four MIDC namely, Waluj, Chikhalthana, Railway Station and Paithan could be considered. However, comparatively the land that Newasa MIDC had an advantage in terms of location and well developed infrastructure, close to State Highway. The Newasa MIDC land is economical as compared to MIDC land available at the other sites and as the project requires abundant land area, the Newasa MIDC land was preferred. 3.3.2 Selection of the Proposed Site The project is being proposed to set-up at MIDC Newasa Industrial Area, as the location is an industrial land under the authority of Maharashtra Industrial Development Corporation (MIDC); it facilitates all statutory clearances required for running manufacturing companies as compared to free hold land. Newasa MIDC is not situated within the city limits, which was an advantage as no residential area is in proximity and thus will not be affected by the ancillary effects of the manufacturing unit. (For e.g. Noise, odor etc)

The land is situated in the D-Zone of the development sector and the unit is entitled to subsidiaries like power, interest cost, and sales tax. Newasa Industrial area is in the vicinity of Taluka places namely, Kanad, Sillod, Soyagaon, Vaijapur and Phulambri. Corns are extensively cultivated in all these areas, this will greatly facilitate the procurement of corn cobs due to easy availability and cheaper transportation costs. The product Furfural can also be produced from bagasse as the main raw material. Bagasse is abundantly available in Newasa region and is in vicinity to the company s site in Newasa owing to number of sugar factories located nearby. 3.4 SIZE OR MAGNITUDE OF OPERATION: The proposed project will be set-up on 48400 sq.mtr (over 12 Acres) land at Newasa MIDC. The facility will have a manufacturing plant with state of the art technology. The company is also putting up agro research centre at the site with well-equipped and designed research and development laboratory for API Intermediate. The company has high consciousness for environmental protection and has established an Effluent Treatment Plant for treating any type of chemical effluent. Sr. No PRODUCT CAPACITY 1 Hydrogen Gas 18.72 Lacs NM 3 2 Furfuraldehyde 600 Tons 3 Furfuryl Alcohol 360 Tons 4 Mono Iso Propyl Amine 120 Tons 5 Di Methyl Amine Hydrochloride 1200 Tons 6 Furfurylamine 240 Tons 7 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole Crude) 100 Tons 8 5-Chloro-4-Amino-2,1,3- Benzothiadiazole 24 Tons 9 2-Furoic Acid 60 Tons 10 Cyclohexenyl Ethyl Amine (CHEA) 120 Tons

3.5 PROJECT DESCRIPTION WITH PROCESS DETAILS A) Hydrogen Gas from Methanol Cracking Galaxy Laboratories Private Limited (Newasa) is the first company, along with M/S. Muse Consultants & Multifab Engineers (Mumbai) to set up the first Indian made Hydrogen Plant. The Hydrogen Plant will work on the technology of producing hydrogen gas from methanol cracking. Technical Details The basic reaction of methanol decomposition/ reforming comprises of two parts: CH 3 OH + H 2 O = CO 2 + 3H 2 Heat of Reaction = - 49.5 kj/mol The basic process of methanol decomposition consists of the following steps: Mixing of methanol and Demineralized water (D.M. Water). Preheating and evaporation of the methanol/water mixture. Methanol decomposition and shift conversion. Process gas cooling and condensate separation. Purification in PSA unit. (The hydrogen is purified in a PSA unit operating with a hydrogen recovery rate of approx. 75% - 80 %.) Route of Synthesis for Hydrogen Gas + H H Methanol Water Hydrogen Gas Carbon di Oxide (MW-32) (MW-18) (MW-2) (MW- 44)

FLOW CHART FOR HYDROGEN GAS MANUFACTURING Vent Gases (55-88% CO2 + 0-2% CO + 40% H2) v/v i) Methanol (1180 TPA) ii) D.M.Water (675 TPA) Batch Tank Pre-heater Reactor Filled with Catalyst (Stationary Bed at 280 0 C) Condenser Heating with Thermopac Separator 14.22 Lacs NM 3 /Annum at 190 NM 3 /Hr (Vent Gases are vented at 11 meter height with flame arrester at the top) PSA Section Seal Pot H2 Purging vessel Compressor Evaporator Recovered Methanol + Water (Recycled to Batch Time and to Evaporator) Hydrogen Purification Unit Cooling with Cooling Water Hydrogen Gas (Purity 99.99%) Storage in MS cylinder having capacity 5.7 NM 3 per cylinder at 150 Kg/cm 2 (18.72 Lacs NM 3 /Annum at 250 NM 3 /Hr)

B) Furfuraldehyde (Furfural) Technical Details Furfuraldehyde is an organic compound derived from a variety of agricultural products such as corn cobs, oat, wheat bran and sawdust. The process of furfural includes hydrolysis of pentosan, which is present in the above mentioned agricultural products. Galaxy is currently aiming at producing furfural from corn cobs using sulphur trioxide and steam at high temperature. The R & D of Galaxy Laboratories Private Limited is in the process of developing seeds for corn cobs with high pentosan content. The company has filed a patent for A Process for Preparing Furfural. (Copy of Patent Novelty Search Report is enclosed) Corn cobs are cut into 3 to 6 mm size and subjected to vapor phase hydrolysis using sulphur trioxide gas and steam at elevated temperature and pressures in cylindrical vessel. The process generates formation of Furfural along with other chemicals. The Furfural thus generated is then taken out of the cylindrical vessel by using dry steam under pressure and these vapors are cooled and fractionated to obtain Furfural along with other by-products namely Acetic Acid, Acetone and Methanol. By employing specific conditions of temperature, pressure and relative concentrations of sulphur trioxide, 9 to 12% furfural yield is extracted. Route of Synthesis for Furfuraldehyde Dilute H 2SO 4 Pentosan Furfuraldehyde (MW-150) (MW- 96.09)

FLOW CHART FOR FURFURAL MANUFACTURING i) Corn Cobs ii) Dilute H 2 SO 4 Spent Corn Cob To Boiler Feed Caustic Lye Digester for Corn Cobs Filter Furfural Crude & Water Top Layer Bottom Layer Furfural Pure Distillation Unit For Separation of Water Layer for ETP Reside sent to Hazardous Waste Facility (Output: 12 to 12.4 MT/ANNUM)

C) Furfuryl Alcohol Furfural (Furfuraldehyde) is reacted with Hydrogen Gas in liquid phase using Raney Nickel Catalyst to form Furfuryl Alcohol. By employing specific conditions of temperature, pressure and relative concentrations of these three components, a high selectivity is achieved at relatively low pressures of Hydrogen leading to over 95% yield. Technical Details: Stage I: In an 1100 Liters Autoclave, charge specific quantity of Furfural and Raney Nickel Catalyst. Close the autoclave and flush it with nitrogen to remove trapped air in the empty space of the autoclave. Then flush the autoclave with Hydrogen to remove Nitrogen from the empty place. Keep 0.5 Kg/cm 2 hydrogen gas pressure in the autoclave and slowly heat the reaction mass in the autoclave at 139 to 140ºC. The pressure in the autoclave will start rising. Keep very slow purging of Hydrogen gas and maintain Hydrogen gas at 15 to 15.5 Kg/cm 2 and temperature at 139 to 140ºC. Apply intermittent heating or cooling to maintain these conditions. After 15 hours of reaction start drawing sample for GC analysis and check for conversion. At the end of 20 to 22 hours Furfuryl Alcohol conversion will reach to 95 to 96% level with 4.5 to 3.5% level Unreacted Furfural and impurity level of 0.4 to 0.6%. Stop the reaction at this stage by applying cooling, release hydrogen, flush the Autoclave with nitrogen and filter the batch to get crude Furfuryl Alcohol. Stage II: Crude Furfuryl Alcohol obtained in the Stage I is taken in a distillation still and distilled under vacuum (5mm of Hg) to recover Furfuryl Alcohol (99.5%) & Furfural (98.5%). The company has filed a patent for A Process for Preparing Furfuryl Alcohol. (Copy of Patent novelty search report is enclosed) Route of Synthesis for Furfuryl Alcohol Nickel Catalyst + + H H Furfural Hydrogen Gas Furfuryl Alcohol Tetrahydro Furfural Alcohol (MW-96.09) (MW-2) (MW-98.10) (MW-102.13)

FLOW CHART FOR FURFURAL ALCOHOL MANUFACTURING i) Furfural Crude Liquid ii) Nickel Catalyst iii) Hydrogen Gas Pure Furfuryl Alcohol Autoclave 20 to 25 Kg/cm 2 90 to 95 ºC High Vacuum Fractional Distillation System Pressure Filter Residue sent to Hazardous Waste Facility (Output 7.2 to 7.6 MT/Annum) Furfural Alcohol Crude Transferred to Distillation

D) Mono Iso Propyl Amine (MIPA) Stage I In a high pressure Autoclave charge acetone, Liquor Ammonia and Nickel Catalyst. Close the autoclave. Take 5 kg pressure of Hydrogen Gas in the autoclave and start stirring and heating. Heat the reaction contents to 55 C, hydrogenation starts. Maintain reaction temperature in the range 55 to 65 C by circulating cooling water in the jacket. Carry out reaction of Hydrogenation at 55 to 65 C maintaining Hydrogen pressure at 5 to 6 kg/cm 2 for three hours. When the absorption of hydrogen gas in the reaction mass is ceased, draw a sample and analyzed on gas chromatogram to confirm complete conversion of Acetone. Cool the reaction mass in the autoclave to 40 to 50 C by providing cooling in the jacket. Settle the reaction mass for 1 hour. Release Hydrogen gas pressure from the autoclave. Flush the autoclave with Nitrogen gas and filter the batch using sparkler filter to obtain crude MIPA. This filtrate is taken for fractional distillation. Catalyst is deactivated with dilute Hydrochloric acid and sent to the manufacturer for regeneration. Stage II The crude MIPA obtained from the above step is fractionated in a fractional distillation unit to separate pure MIPA along with various impure fraction containing impurities. During the course of fractional distillation, samples are drawn at regular intervals and distillation column is continuously monitored by controlling vacuum & temperature to separate various impurities as impure fractions. By maintaining proper reflux ratios and other conditions, pure MIPA is collected as main fraction a special receiver assigned for it. It is then checked for final quality testing and if found ok then packed and transferred to finished goods storage. Route of Synthesis for Mono Iso Propyl Amine + + H H Nickel Catalyst Acetone Ammonia Hydrogen Gas Mono Propyl Amine (MW-58.08) (MW-17) (MW-2) (MW-59.11)

FLOW CHART FOR MONO ISO PROPYL AMINE MANUFACTURING i) Acetone ii) Ammonia (Liquor) iii) Nickel Catalyst iv) Hydrogen Gas Autoclave 5 to 6 Kg/cm 2 55 to 65 ºC High Vacuum Fractional Distillation System Pure Mono Iso Propyl Amine Pressure Filter Residue sent to Hazardous Waste Facility (Output 2.4 to 2.6 MT/Annum) Mono Iso Propyl Amine Crude Transferred to Distillation

E) Di Methyl Amine Hydrochloride (DMA.HCl) Stage I In a reactor fitted with column condenser & receiver, charge Dimethylamine (40%) dissolved in Water. Start stirring and add required quantity of Hydrochloric (30%) to adjust ph of the reaction mixture at 6 to 6.5. Stir the contents for 1 hour and apply slow heating and vacuum to distill out specific quantity of water while maintaining reaction temperature at 45 to 50 C. Cool the contents to 25 C and centrifuge the crystallized DMA.HCl. Collect the Mother Liquor and use for next batch. Stage II The Crystalline DMA.HCl obtained above is the dried in Rotary Cone Vacuum Dryer (RCVD) for 8 hours at 40 C. It is then unloaded and packed in Fiber board Drums. Route of Synthesis for Di Methyl Amine Hydrochloride + H CL Dimethylamine Hydrochloric Acid Dimethylamine Hydrochloride (MW-45.10) (MW-36.50) (MW-81.60)

FLOW CHART FOR DI METHYL AMINE HYDROCHLORIDE MANUFACTURING i) Di Methyl Amine ii) HCl Reactor Dryer Pure Di Methyl Amine HCl Centrifuge Mother Liquor Recycle

F) Furfurylamine It is produced by Reductive Amination of Furfural with Ammonia and Hydrogen Gas in liquid phase using Raney Nickel catalyst to form Furfurylamine with very high level of selective leading to primary amines. Technical Details: Stage I: In an 1100 Liters Autoclave, charge specific quantity of Furfural, ammonia and Raney Nickel Catalyst. Close the autoclave and flush it with nitrogen to remove trapped air in the empty space of the autoclave. Then flush the autoclave with Hydrogen to remove Nitrogen from the empty place. Keep 0.5 Kg/cm 2 hydrogen gas pressure in the autoclave and slowly heat the reaction mass in the autoclave at 139 to 140ºC. The pressure in the autoclave will start rising. Keep very slow purging of Hydrogen gas and maintain Hydrogen gas at 12 to 13.5 Kg/cm 2 and temperature at 65 to 95ºC. Apply intermittent heating or cooling to maintain these conditions. After 22 hours of reaction start drawing sample for GC analysis and check for conversion. At the end of 20 to 22 hours Furfurylamine conversion will reach to 94.5 to 95% level with total impurities in the range 5 to 5.5% level with no trace of Unreacted Furfural. Stop the reaction at this stage by applying cooling, release hydrogen, flush the Autoclave with nitrogen and filter the batch to get crude Furfurylamine. Stage II: Crude Furfurylamine obtained in the Step 1 is taken in a distillation still and distilled under vacuum (2mm of Hg) to recover Furfurylamine (99.5%). The company has filed a patent for Improved Process for Furfurylamine. (Copy of patent is enclosed) Route of Synthesis for Furfurylamine + + H H Nickel Catalyst Furfuraldehyde Ammonia Hydrogen Gas Furfurylamine (MW-96.09) (MW-17) (MW-2) (MW-97)

FLOW CHART FOR FURFURYLAMINE MANUFACTURING i) Furfural Crude ii) Ammonia (Liquor) iii) Nickel Catalyst iv) Hydrogen Gas Autoclave 18 to 20 Kg/cm 2 95 to 105 ºC High Vacuum Fractional Distillation System Pure Furfurylamine Pressure Filter Residue sent to Hazardous Waste Facility (Output 4.8 to 5.2 MT/Annum) Furfurylamine Crude Transferred to Distillation

G) 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole Crude) Stage I: (Condensation & Hydrolysis) Charge Dimethyl Formamide and 2, 3 Dichloro Phenol. Start stirring and heat at temperature 50 to 60 C. Charge potassium carbonate, stop heating, start cooling and add nitro compound at temperature 30 to 40 C. Start heating, start distillation and complete. Charge methanol, start stirring and add caustic solution, maintain temperature at 50 to 55 C. Then charge water at 40 C. After addition is complete, stir for 30 min and then start centrifuge. Stage II: (Hydrogenation) Charge Methanol, PNA, & Catalyst, and flush with Nitrogen and Hydrogen. Start stirring and hydrogen feeding. Give heat by applying steam in jacket and heat upto 45-46 C and stop heating. Continue reaction at 55-60 C till hydrogen pressure inside is upto 5kg/cm 2. Use cooling water circulation in jacket, once there is no further rise in temperature and drop in pressure is noticed at 5kg/cm 2 for at least 30 minutes. When the end point of reaction is indicated, stop hydrogen purging and stirring and allow settling for 1 Hr. Release hydrogen pressure slowly up to 0.5 kg/cm 2, flush with nitrogen pressure and filter through pressure filter. Stage III: (Cyclization) Charge Methanolic solution in room temperature, add caustic lye under continuous stirring and cool to 40 C. Start CS2 addition at 40 C and complete addition in 6 Hrs. After CS2 addition stir for ½ Hr. Start heating and reflux for 10 Hrs. Charge water, heat to 80 C and maintain for one Hr. Cool to 60 C and start addition of acetic acid between 3-4 Hrs. After addition of acetic acid stir for ½ Hr. Check the ph of reaction mass is 6 7. Centrifuge and unload the material. Stage IV: (Methylation) Charge Methanol with above stage III material at room temperature and stir for 1 Hr and slowly add DMS at 35-40 C. Start heating slowly to 65 C to maintain reflux for 8 Hrs. After completing the reaction, cool the reaction & filter through centrifuge.

Stage V: (Charcoal Treatment & Neutralization with Ammonia) Charge Methanol and above stage IV material and heat upto 60-65 C. Charge charcoal and maintain for 1 Hr. Filter the reaction mass and collect the filtrate in SS reactor. Cool the reaction mass at room temperature and add Liquor ammonia. Centrifuge the material and dry to get the product in powder form. Route of Synthesis for 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole Crude) Stage I: (Condensation & Hydrolysis) + K 2 CO 3 2,3 Dichlorophenol 3,4-Dichloro-6-Nitro Acetanilide 4-chloro-5(2,3-dichloro phenoxy)-2-nitrophenyl acetamide (MW-163.00) (MW-249.05) (MW-375.59)

+ H 2 O MeOH/Caustic Lye 4-chloro-5(2,3-dichloro phenoxy)-2-nitrophenyl acetamide Water 5-chloro-4-(2,3- dichlorophenoxy)-2- nitroaniline (MW-375.59) (MW-18.00) (MW-333.55) Stage II: (Hydrogenation) H2/R.N.Catalyst/MeOH 3H2 5-chloro-4-(2,3- dichlorophenoxy)-2- nitroaniline Hydrogen Gas 4-chloro-5-(2,3- dichlorophenoxy)-1,2- Phenylenediamine (MW-333.55) (MW-6.00) (MW-303.55)

Stage III: (Cyclization) CS2/Caustic Lye/CH3COOH CH3OH 4-chloro-5-(2,3- dichlorophenoxy)-1,2- Phenylenediamine Carbon Di Sulfide 5-chloro-6-(2,3-dichlorophenoxy)- 1,3- dihydro Benzimidazole-2- Thione (MW-303.55) (MW-76.04) (MW-345.55) Stage IV: (Methylation) DMS 5-chloro-6-(2,3-dichlorophenoxy)- 1,3- dihydro Benzimidazole-2- Thione Di Methyl Sulphate (MW-345.55) Stage V: (Charcoal Treatment (MW-126) & Neutralization with Ammonia) (MW-471.55) 5-chloro-6-(2,3-dichlorophenoxy)-2- Methylthio-1H-Benzimidazole Methosulphate MeOH/Charcoal Ammonia 5-chloro-6-(2,3-dichlorophenoxy)-2- Methylthio-1H-Benzimidazole Methosulphate (MW-471.55) 6-chloro-5-(2,3-dichlorophenoxy)-2- Methylsulfonyl-1H-Benzimidazole (MW-359.65)

FLOW CHART FOR 6-CHLORO-5(2,3 DICHLOROPHENOXY)-2-METHYLTHIO 1H BENZIMIDAZOLE (TRICLABENDAZOLE CRUDE) MANUFACTURING Stage I: (Condensation & Hydrolysis) i) Dimethyl Formamide ii) 2,3 Dichloro Phenol iii) Potassium Carbonate SSR (Condensation) SSR (Hydrolysis) Centrifuge 4-Chloro-5-(2, 3- Dichloro phenoxy)-2-nitroaniline (Stage- (Stage-I) Dimethyl Formamide Recovery i) Methanol ii) Caustic Lye iii) Water ML Transferred to Recovery Stage II: (Hydrogenation) vi) Methanol vii) Stage-I Stage-I viii) Raney mm Raney Nickel Nickel Catalyst iv) Catalyst Nitrogen Gas ix) v) Hydrogen Nitrogen Gas SSR Filtration 4-Chloro-5-(2, 3- Dichlorophenoxy)-1, 2-2- Phenylenediamine (Stage-II)

Stage III: (Cyclization) i) Stage-II with Methanol ii) Caustic Lye iii) Carbon Disulphate iv) Acetic Acid SSR Centrifuge 5-Chloro-4-(2,3- dichlorophenoxy)-1,3- dihydrobenzimidazole-2- thione (Stage-III) ML Transferred to Recovery Stage IV: (Methylation) i) Methanol ii) Stage-III iii) Dimethyl Sulphate GLR Centrifuge 5-Chloro-6-(2,3-Dichlorophenoxy)- 2-(Methylsulphate)-1H- Benzimidazole (Stage-IV) Methanol ML Transferred to Recovery

Stage V: (Charcoal Treatment & Neutralization with Ammonia) i) Methanol ii) Stage-IV iii) Charcoal GLR Filtration SSR Centrifuge Drying Milling 6-Chloro-5(2,3-Dichloro phenoxy)-2-methylsulfonyl- 1-H Benzimidazole (Triclabendazole Crude N- 1) (Stage-V) Liquor Ammonia Methanol ML Transferred to Recovery

H) 5-Chloro-4-Amino-2,1,3- Benzothiadiazole Stage I (Hydrogenation) Charge Ethyl Acetate Charge PCONA (Para Chloro Nitro Aniline) Charge Raney Nickel Catalyst Apply Hydrogen Gas & Hydrogen Pressure 4 Kg/cm 2 Continue Hydrogenation by Maintaining Temperature at 60 65 C After Completion of reaction, filter reaction mass through Nutsche filter and wash the bed with 50.0 L Ethyl Acetate Take Ethyl Acetate filtrate in clean and dry vessel and distill Ethyl Acetate under vacuum below 35-40 C Drain the material in the drum Stage II (Cyclization) Charge Dimethyl Formamide Charge Stage I Material, stir the material for 30 Minutes at Room Temperature Add Thionyl Chloride in 3-4 Hrs at 30 35 C After Completion of reaction, quench the reaction mass in chilled water Adjust the ph by the caustic solution ph upto 7 Centrifuge the material Stage III (Nitration) Charge Sulphuric Acid & cool to 10 C Charge Stage II, stir the material for 30 Minutes at Room Temperature After that slowly add Nitric acid, Temperature should be below 20 C After completion of reaction mass, quench in chilled water Centrifuge the material Stage IV (Reduction) Charge Water / Toluene Slowly add Iron powder Charge Stage III, heat slowly to 60 C and maintain for 2-3 hours After completion of reaction, filter the reaction mass and collect the filtrate in SSR Start toluene recovery under vacuum temperature 50-55 C Filter the material in centrifuge and wash with methanol and suck dried to unload the material Dry the material at temperature 60-65 C, unload and pack the material as finished product.

Route of Synthesis for 5-Chloro-4-Amino-2,1,3-Benzothiadiazole Stage I (Hydrogenation) Catalyst/H2/Ethyl Acetate Para Chloro Ortho Nitro Aniline (MW-172.57) 4-Chlorobenzene-1,2- Diamine (MW-142.60) Stage II (Cyclization) DMF/SOCl2 4-Chlorobenzene-1,2- Diamine (MW-142.60) 5-Chloro-2,1,3- Benzothiadiazole (MW-170.62)

Stage III (Nitration) H2SO4/HNO3 5-Chloro-2,1,3- Benzothiadiazole (MW-170.62) 5-Chloro-4-Nitro-2,1,3- Benzothiadiazole (MW-216.00) Stage IV (Reduction) Iron/Toluene Methanol 5-Chloro-4-Nitro-2,1,3- Benzothiadiazole (MW-216.00) 5-Chloro-4-Amino- 2,1,3-Benzothiadiazole (MW-185.63)

FLOW CHART FOR 5-CHLORO-4-AMINO-2,1,3- BENZOTHIADIAZOLE MANUFACTURING Stage I (Hydrogenation) i) Ethyl Acetate ii) PCONA iii) Raney Nickel iv) Hydrogen Gas v) Nitrogen Gas SSR Filter SSR 4-Chlorobenzene- 1, 2-Diamine (Stage-I) Spent Catalyst sent for Reaction Ethyl Acetate Recovery Stage II (Cyclization) i) Di Methyl Formamide ii) Stage-I iii) Thionyl Chloride GLR GLR Centrifuge 5-Chloro-2, 1, 3- Benzothiadiazole (Stage-II) Caustic Lye Quenching with Water & Ice ML Transferred to ETP

Stage III (Nitration) i) Sulphuric Acid ii) Stage-II iii) Nitric Acid Sulphuric SSR Acid Sintex Sintex Centrifuge Centrifuge 5-Chloro-4-Nitro-2, 1, 3-1, 3- Stage-II Benzothiadiazole (Stage-III) (Stage-III) Quenching with Water & Ice ML Transferred to ETP Stage IV (Reduction) v) i) Water vi) ii) Toluene iii) vii) Iron viii) iv) Stage-III SSR Filter SSR Centrifuge Drying Milling 5-Chloro-4-Amino-2, 1, 3-Benzothiadiazole (Stage-IV) Iron slug transferred to hazard waste Toluene Recovery ML Transferred to recovery Methanol Washing

I) 2-Furoic Acid Stage I (Oxidation) Charge filter water and add Caustic Flakes under cooling. Start chilling upto 10 to 15 C. Start purging of chlorine at temperature below 15 C. Check ph & assay of hypochlorite solution. Addition of Furfural Aldehyde at temperature below 20 C. Digestion of reaction mass for 5 to 6 hours. Check ph & assay of hypochlorite solution. (Limit NMT 1%) Charge sodium chloride and stir for 60 minutes. Adjust the ph 7 (Neutral) by Hydrochloric Acid. Reaction mass to be transferred to GLR-03. Addition of Hydrochloric Acid upto ph Range 2 to 2.5. Check the ph & stir for 50 minutes. Centrifuge the material. Wash with 20% NaCl solution and unload the material. Stage II (Purification) Charge filter water and charge 2-Furoic Acid crude material. Heat upto 50 C, then charge charcoal and start heating upto 95 to 100 C. Maintain temperature at 90 to 95 C for 1 hour. Start filtration & filtrate to be collected in GLR-02.

Stir & start cooling at room temperature. Start brine circulation, chill upto 15 to 20 C and maintain 1 hour. Centrifuge the material & wash with chilled water. Unload the material. Dry the material temperature at 65 to 70 C. Dry the material till LOD (Limit NMT 0.5%) Unload the material & Pack. Route of Synthesis for 2-Furoic Acid + + HCl Furfural Sodium Hypochlorite 2-Furoic Acid (MW-96) (MW-73.50) (MW-112)

FLOW CHART FOR 2-FURIOC ACID MANUFACTURING Stage I (Oxidation) v) i) Water vi) ii) Caustic Flakes vii) iii) Chlorine viii) iv) Furfural Furfural SSR GLR Centrifuge 2-Furoic Acid Crude Hydrochloric Acid Hydrochloric Acid Aqueous mother liquor containing Sodium Chloride Stage II (Purification) iv) i) ix) Water v) ii) x) Caustic Stage-I Flakes vi) iii) xi) Chlorine Charcoal xii) Furfural GLR Filter GLR Centrifuge Aqueous mother liquor (Recycle) 2-Furoic Acid Pure Drying Milling 2-Furoic Acid (Pure) Packing

J) Cyclohexenyl Ethyl Amine (CHEA) Stage I In a high pressure Autoclave, charge Cyclohexenyl Acetonitrile (CHAN), Catalyst and Toluene. Close the autoclave. Take 10 kg pressure of Hydrogen Gas in the autoclave and start stirring and heating. Heat the reaction contents to 70 C. Hydrogenation starts. Maintain reaction temperature in the range 70 to 80 C by circulating cooling water in the jacket. Carry out reaction of Hydrogenation at 70 to 80 C and maintain 10 to 15 kg/cm 2 pressure for six hours. When the absorption of hydrogen gas in the reaction mass is ceased, draw a sample and analyze on gas chromatogram to confirm complete conversion of CHAN. Cool the reaction mass in the autoclave to 40 to 50 C by providing cooling in the jacket. Settle the reaction mass for 1 hour. Release Hydrogen gas pressure from the autoclave. Flush the autoclave with Nitrogen gas and filter the batch using sparkler filter to obtain crude Cyclohexenyl Ethylamine (CHEA) and toluene mixture. This filtrate is taken for fractional distillation. Catalyst is deactivated with dilute Hydrochloric acid and sent to the manufacturer for regeneration. Stage II The crude Cyclohexenyl Ethylamine obtained from stage I is fractionated in a fractional distillation unit to separate pure Cyclohexenyl Ethylamine along with Toluene and various impure fraction containing impurities. During the course of fractional distillation, samples are drawn at regular interval and fractional column is continuously monitored by controlling vacuum & temperature to separate various impurities as impure fractions. By maintaining proper reflux ratios and other conditions pure Cyclohexenyl ethyl amine is collected as main fraction in a special receiver assigned for it. It is then checked for final quality testing and if found ok, pack and transfer to finished goods storage. Route of Synthesis Cyclohexenyl Ethyl Amine (CHEA) + H H Nickel Catalyst Toluene Cyclohexene-1- Acetonitrile Hydrogen Gas Cyclohexenyl Ethylamine (MW-121.18) (MW-2) (MW-125.21)

FLOW CHART FOR CYCLOHEXENYL ETHYL AMINE (CHEA) MANUFACTURING i) Cyclohexenyl Acetonitrile ii) Toluene iii) Nickel Catalyst iv) Hydrogen Gas Autoclave 10 to 15 Kg/cm 2 70 to 80ºC High Vacuum Fractional Distillation System Toluene Recycled for Process Pure Cyclohexenyl Ethyl Amine Pressure Filter Residue sent to Hazardous Waste Facility (Output 2.4 to 2.6 MT/Annum) Cyclohexenyl Ethyl Amine Crude Transferred to Distillation

3.6 RAW MATERIAL REQUIRED ALONG WITH ESTIMATED QUANTITY, LIKELY SOURCE, MARKETING AREA OF FINAL PRODUCTS, MODE OF TRANSPORT OF RAW MATERIALS AND FINISHED PRODUCTS: 3.6.1 Raw Material Required Along with Estimated Quantity Sr. No. List of Raw Material and their annual consumption Name of Raw Material Raw Material Consumption Per Annum Unit Hydrogen Gas (Capacity: 18.72 Lacs NM 3 TPA) 1 Methanol 1180.00 TPA 2 D.M Water 675.00 TPA Furfuraldehyde (Capacity: 600 TPA) 1 Corn Cobs 7038.00 TPA 2 Sulphuric Trioxide 210.00 TPA Furfuryl Alcohol (Capacity: 360 TPA) 1 Furfuraldehyde 396.00 TPA 2 Raney Nickel Catalyst 18.00 TPA 3 Hydrogen Gas (NM 3 ) 129.60 TPA 4 Nitrogen Gas (NM 3 14.40 TPA Mono Isopropyl Amine (Capacity: 120 TPA) 1 Acetone 146.00 TPA 2 Ammonia (Liquor) 34.50 TPA 3 Raney Nickel Catalyst 6.00 TPA 4 Hydrogen Gas (NM 3 ) 43.20 TPA 5 Nitrogen Gas (NM 3 ) 4.80 TPA Di Methyl Amine Hydrochloride (Capacity: 1200 TPA) 1 Di Methyl Amine (40%) 2088.00 TPA 2 HCl (30%) 1030.00 TPA Furfurylamine (Capacity: 240 TPA) 1 Furfuraldehyde 280.00 TPA 2 Ammonia Gas 52.80 TPA 3 Raney Nickel Catalyst 12.00 TPA 4 Hydrogen Gas (NM 3 ) 86.40 TPA 5 Nitrogen Gas (NM 3 ) 9.60 TPA 6-Chloro-5(2,3- Dichlorophenoxy)-2-Methylthio 1H Benzimidazole Triclabendazole (Crude) (N- 1) (Capacity: 100 TPA)

1 2,3 Dichloro Phenol 72.50 TPA 2 4,5 Dichloro-2-Nitroacetanilide 109.00 TPA 3 Dimethyl formamide 110.00 TPA 4 Potassium Carbonate 66.70 TPA TPA 5 Methanol 1800.00 TPA 6 Caustic Lye 115.00 7 Hydrogen Gas (NM 3 ) 32.00 TPA TPA 8 Raney Nickel Catalyst 1.80 TPA 9 Carbon disulphide 47.00 TPA 10 Acetic Acid 40.00 11 Di methyl Sulphate 67.00 TPA 5-Chloro-4-Amino-2,1,3-Benzothiadiazole (TNZ) (Capacity: 24 TPA) 1 Para Chloro ortho nitro aniline 36.00 TPA 2 Ethyl acetate 30.00 TPA 3 Raney Nickel Catalyst 0.432 TPA 4 Hydrogen Gas (NM 3 ) 12.48 TPA 5 Dimethylformamide 84.00 TPA 6 Thionyl chloride 39.00 TPA 7 Caustic Lye 36.00 TPA 8 Sulphuric Acid 180.00 TPA 9 Nitric Acid 12.33 TPA 10 Iron Powder 26.40 TPA 11 Toluene 56.00 TPA 12 Methanol 28.80 TPA 2-Furoic Acid (Capacity: 60 TPA) 1 Furfural Aldehyde 90.00 2 Caustic Flakes 128.40 3 Chlorine 75.60 4 Sodium Chloride 57.60 5 Charcoal 750.00 TPA TPA TPA TPA TPA Cyclohexenyl Ethyl Amine (Capacity: 120 TPA)

1 Cyclohexenyl Acetonitrile 162.00 TPA 2 Toluene 24.12 TPA TPA 3 Raney Nickel Catalyst 6.00 TPA 4 Hydrogen Gas (NM 3 ) 69.12 TPA 5 Nitrogen Gas (NM 3 ) 4.90 3.6.2 Raw Material Source Sr.No Product Source of Raw Materials for Products Key Raw Materials Raw Material Source 1 Hydrogen Gas Methanol It is indigenously and abundantly available in India. Non-Petroleum based and therefore their availability is without much variation in input prices. 2 Furfuraldehyde Corncobs/Bagasse Corncobs are available in Aurangabad distreict predominantly in Kannad, Sillod, Soyagaon, Vaijapur, Phulambri and Jalgaon district. 3 Furfuryl Alcohol Furfuraldehyde Bagasse is abundantly available in Ahmednagar district as many sugar factories are located nearby. Galaxy is going to manufacture Furfuraldehyde, it can be consumed captively whenever required. 4 Furfurylamine Furfuraldehyde Galaxy is going to manufacture Furfuraldehyde, it can be consumed captively whenever required. 5 2-Furioc Acid Furfuraldehyde Same as above 6 Mono Iso Propyl Amine Acetone It is indigenously and abundantly available in India. 7 Di Methyl Amine Di Methyl Amine Hydrochloride

Non-Petroleum based and therefore their availability is without much variation in input prices. 8 Cyclohexenyl Ethyl Amine (CHEA) Cyano Acetic Acid Cyano Acetic Acid is available only in China and can be imported in huge quantity when required. 9 6-Chloro-5(2,3 Dichlorophenoxy)-2- Methylthio Benzimidazole (Triclabendazole Crude) 1H 10 5-Chloro-4-Amino- 2,1,3- Benzothiadiazole (TNZ) 4,5-Dichloro 2-Nitro Acetanilide (TC-III) Para Chloro Ortho Nitro Aniline Triclabendazole Crude is a product which involves multiple stages and the previous output becomes the raw material input for the next stage of operation. Galaxy will procures material from outside for the first three stages and processes it ahead. It is indigenously and abundantly available in India. 3.6.3 Marketing Area of Final Products Galaxy proposes to continue its existing strategy of direct marketing both for the domestic market as well as for its new products for exports. Furfural, Furfuryl Alcohol and Furfurylamine are in great demand in India and the consumption of these chemicals is increasing rapidly. Company s API Intermediates namely, 2-Furioc Acid, 5-Chloro-4-Amino-2,1,3- Benzothiadiazole (TNZ), 6-Chloro-5(2,3 Dichlorophenoxy)-2-Methylthio 1H Benzimidazole (Triclabendazole Crude), Cyclohexenyl Ethyl Amine (CHEA), Di Methyl Amine Hydrochloride are currently being sold to multi-national companies (MNC s) like Dr. Reddy s Laboratories, Sequent Scientific, Wochardt Ltd, Survival Technologies, NGL Pharma, etc. The company has identified higher demand for these products from existing and new customers. Galaxy has already developed its own marketing network for local as well as for exports. As a policy, company has restricted intermediaries since inception. Since Galaxy s brand is well established for Furfurylamine, Furfuryl Alcohol and other existing products the company would not face constraints in marketing the proposed products. Galaxy stands fully committed to its quality since beginning and this has given the company brand name in local and export market. Company is well known for its products.

The processes developed for MIPA, DMA.HCl ensures high profitability due to high yields and in-house availability of Hydrogen Gas with no dependability on petroleum products & their ever increasing prices. Therefore, Galaxy can market these products at a competitive price compared to the others. The demand for Hydrogen gas is increasing for its property of making the chemical processes pollution free. The captive consumption of hydrogen gas will benefit the other products of the company by making them cost effective. Galaxy will have tie-ups with agents to transport the surplus hydrogen gas to customers with requirement of the same. 3.6.4 Mode of Transportation of Raw Materials and Finished Products The aforesaid raw materials are transported by road/sea/air to the manufacturer s site at Newasa (Pune-Aurangabad Highway). 3.7 RESOURCE OPTIMIZATION/RECYCLING AND REUSE ENVISAGED IN THE PROJECT Corn cob which is a waste will be used as a raw material for manufacturing of furfuraldehyde. Biomass generated in this product is of good fuel value and can be directly used as boiler fuel. After treatment of waste water these water will be used for gardening. 3.7 AVAILABILTY OF WATER ITS SOURCE, ENERGY/POWER REQUIREMENT AND SOURCE SHOULD BE GIVEN Sr.No PARTICULARS REQUIREMENT SOURCE 1 Water 84 M 3 /Day Water will be supplied by Newasa MIDC. 2 Power 320 KVA (Capacity of Transformer) The power is given by the MSEB (Maharashtra State Electricity Board). Subsidies are provided by MSEB on completion of the project.

3.8 QUANTITY OF WASTE TO BE GENERATED (LIQUID AND SOLID) AND SCHEME FOR THEIR MANAGEMENT/DISPOSAL Sr. No Product Waste Quantity Management / treatment 1 Hydrogen Gas Vent Gases Carbon di oxide CO2-55-88% + Carbon Oxide CO - 0-2% + Hydrogen H2-40% v/v 14.22 Lacs NM 3 /Annum at 190 NM 3 /Hr The vent gases will be collected in the seal pot, of which Hydrogen is discharged through 11 Mtr height chimney with flame arrester and CO2 will be collected from the seal pot and sold. 2 Furfuraldehyde Distillation Residue 12 to 12.4 MT/ANNUM 3 Furfuryl Alcohol Distillation Residue Output 7.2 to 7.6 MT/Annum 4 Furfurylamine Distillation Residue 4.8 to 5.2 MT/Annum The waste will be collected and treated in Common hazardous waste management & treatment facility at Ranjangaon. 5 Mono Iso Propyl Amine 6 Cyclohexenyl Ethyl Amine (CHEA) 7 Di Methyl Amine Hydrochloride Distillation Residue 2.4 to 2.6 MT/Annum Distillation Residue 2.4 to 2.6 MT/Annum Nil Zero Discharge - 8 2-Furioc Acid Acidic Water 360 M 3 /Annum Acidic Water treated at Effluent Treatment Plant (ETP) and used for green belt development and for dust suppression / sprinkling purpose. 9 6-Chloro-5(2,3 Dichlorophenoxy)-2- Slight Alkaline Water 600 M 3 /Annum Slight Alkaline Water treated at Effluent

Methylthio Benzimidazole (Triclabendazole Crude) 1H (7.5 to 8 ph) Treatment Plant (ETP) and used for green belt development and for dust suppression / sprinkling purpose. 10 5-Chloro-4-Amino- 2,1,3- Benzothiadiazole (TNZ) Neutral Water (6.5 to 7 ph) 504 M 3 /Annum Neutral Water treated at Effluent Treatment Plant (ETP)and used for green belt development and for dust suppression / sprinkling purpose.

3.10 SCHEMATIC REPRESENTATIONS OF THE FEASIBILITY DRAWING WHICH GIVE INFORMATION OF EIA PURPOSE The applicability of the EIA Notification 2006, for the proposed project was explored by considering different possibilities & provision made in the said notification considering the products & project location. Project concept Screening Category B (As project is in notified industrial area) Project falls under B1 category as per EIA notification 2006 it falls in category 5(f) of schedule I, EIA study is required Form I, PFR+ Proposed TOR Scoping by SEAC TOR approved by SEAC EIA study & Preparation of Report Submission of EIA report to Dept. of Environment Maharashtra Appraisal by SEAC Recommended Not Recommended Approval from SEIAA Grant of EC Rejected

CHAPTER 4 SITE ANALYSIS 4.1 CONNECTIVITY Connectivity The Site is located on Aurangabad-Pune Highway. Distance from Pune : Distance from Aurangabad: Distance from Ahmednagar : Distance from Mumbai : Distance from Nearest Village (Godegaon): 177 Km 73 Km 22 Km 290 Km 1 Km Distance from Nearest Hospital (Shaneshwar Gramin Rugnalay Shanishingnapur) : Distance from Nearest Fire Station (Ahmednagar MIDC): Distance from Nearest Police Station (Sonai): Distance from Nearest Airport (Aurangabad): Distance from Nearest Bus Stand (Godegaon): Distance from Nearest Railway Station (Ahmednagar): Distance from Nearest Sea Port (Mumabai) : 10 Km 22 Km 1 Km 75 Km 1 Km 24 Km 340 Km 4.2 LAND FORM, LAND USE AND LAND OWNERSHIP Sr. No Particulars Description 1 Land Form MIDC Industrial Land (Newasa) 2 Land Use Barren land 3 Land Ownership Maharashtra Industrial Development Corporation - Nashik (Leased to Galaxy Laboratories Pvt Ltd for 99 years)

4.2 TOPOGRAPHY Topography of land is more or less plain terrain without much undulation. Google Map 4.4 EXISTING LAND USE PATTERN Total Land Area Built Up area = 48400 Sq.Mtr = 10275.26 Sq.Mtr Below mentioned table gives brief information regarding environmental setting of the project site: Sr.No Particulars Distance from the Site 1 Forest 5.85 km 2 Water Bodies Stream Panas odha Bhar bhordi odha 4.8 km 4.6 km