Surname Other Names Centre Number Candidate Number Candidate Signature. General Certificate of Secondary Education Higher Tier June 2014

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A Surname Other Names Centre Number Candidate Number Candidate Signature General Certificate of Secondary Education Higher Tier June 2014 Science A Unit Biology B1 Biology Unit Biology B1 BL1HP Friday 6 June 2014 1.30 pm to 2.30 pm At the top of the page, write your surname and other names, your centre number, your candidate number and add your signature. [Turn over]

For this paper you must have: a ruler. You may use a calculator. TIME ALLOWED 1 hour 2 INSTRUCTIONS Use black ink or black ball-point pen. Answer ALL questions. You must answer the questions in the spaces provided. Do all rough work in this book. Cross through any work you do not want to be marked.

3 INFORMATION The marks for questions are shown in brackets. The maximum mark for this paper is 60. You are expected to use a calculator where appropriate. You are reminded of the need for good English and clear presentation in your answers. Question 2 should be answered in continuous prose. In this question you will be marked on your ability to: use good English organise information clearly use specialist vocabulary where appropriate. ADVICE In all calculations, show clearly how you work out your answer. DO NOT TURN OVER UNTIL TOLD TO DO SO

Answer ALL questions in the spaces provided. 4 1 Food chains show the flow of energy through the organisms in a habitat. 1 (a) FIGURE 1 shows a food chain. FIGURE 1 grass sheep human The biomass in each stage of the food chain changes as food passes along the food chain. On the opposite page draw a pyramid of biomass for this food chain. Label the pyramid. [2 marks]

[Turn over] 5

1 (b) TABLE 1 shows three food chains, A, B and C. TABLE 1 Food chain A plants sheep human B plants grasshoppers frogs trout human C plants human 6 1 (b) (i) In which food chain, A, B or C, will the greatest proportion of biomass and energy of the plants be passed to humans? [1 mark]

1 (b) (ii) Give reasons why the food chain that you chose in part (b)(i) passes on the greatest proportion of biomass and energy to humans. [3 marks] 7 6 [Turn over]

2 [In this question you will be assessed on using good English, organising information clearly and using specialist terms where appropriate.] 8 Animals and plants have features (adaptations) that allow them to survive in the conditions in which they normally live. Describe how animals and plants are adapted to survive in dry conditions such as deserts. For each adaptation that you give, describe how the adaptation helps the animal or plant to survive in dry conditions. To obtain full marks you should refer to BOTH animals and plants. [6 marks]

9 [Turn over]

10 6

11 BLANK PAGE [Turn over]

12 3 Most birds sit on their eggs to keep them warm until they hatch. Megapode birds: dig a large hole in sand fill the hole with dead plants lay their eggs on top of the dead plants cover the surface with a thick layer of sand. FIGURE 2 shows a megapode bird s nest. FIGURE 2 Air vent Eggs Sand Dead plants

13 3 (a) The dead plants in the nest decay. The decaying process helps to keep the eggs warm for many weeks. [Turn over] Suggest how. [3 marks]

14 3 (b) (i) Megapode birds open and close the air vents of the nest at different times of the day. Suggest reasons why it is necessary to open and close the air vents. [3 marks]

15 3 (b) (ii) The sex of a megapode bird that hatches from an egg depends on the temperature at which the egg was kept. Use this information to suggest why it is important for megapode birds to control the temperature of their nests. [1 mark] 7 [Turn over]

BLANK PAGE 16

17 4 The MMR vaccine is used to protect against measles. 4 (a) Apart from measles, which TWO other diseases does the MMR vaccine protect against? [1 mark] and [Turn over]

18 4 (b) Read the information. Measles is a dangerous disease caused by a virus. Normally, MMR vaccinations are given at 1 year old and again at 4 years old. Each vaccination is 90% effective in protecting against the measles virus. In April 2013, there were 630 cases of measles in children aged 4 and over in a small area of the UK. Of these cases, 504 children had not been vaccinated against MMR at all and only a few had been given a second vaccination.

19 4 (b) (i) Calculate the percentage of the children who caught measles in April 2013 who had NOT been vaccinated against MMR. [2 marks] Percentage = 4 (b) (ii) Suggest ONE advantage to the population as a whole of children having the second MMR vaccination. [1 mark] [Turn over]

20 4 (c) (i) What does a vaccine contain? [1 mark] 4 (c) (ii) Explain how a vaccination prevents infection. [3 marks]

21 4 (d) (i) Antibiotics can only be used to treat some infections. Explain why antibiotics CANNOT be used to treat measles. [2 marks] 4 (d) (ii) Why do antibiotics become less useful at treating an infection if the antibiotic is overused? [1 mark] [Turn over] 11

22 5 FIGURE 3 shows how a nerve impulse passing along a relay neurone causes an impulse to be sent along another type of neurone, neurone X. FIGURE 3 Impulse Synapse Relay neurone Neurone X Chemical Impulse 5 (a) What type of neurone is neurone X? [1 mark]

23 5 (b) Describe how information passes from the relay neurone to neurone X. [3 marks] Use FIGURE 3 to help you. [Turn over]

24 5 (c) Scientists investigated the effect of two toxins on the way in which information passes across synapses. TABLE 2 shows the results. TABLE 2 Toxin Curare Strychnine Effect at the synapse Decreases the effect of the chemical on neurone X Increases the amount of the chemical made in the relay neurone

25 Describe the effect of each of the toxins on the response by muscles. [2 marks] Curare Strychnine 6 [Turn over]

26 6 Drugs may harm the human body. 6 (a) The drug thalidomide was originally developed in the 1950s. 6 (a) (i) What was the drug thalidomide originally developed to treat? [1 mark] 6 (a) (ii) Soon after it was developed, thalidomide was found to be useful in treating another condition. What was this other condition? [1 mark]

27 6 (a) (iii) Describe ONE harmful effect of thalidomide. [1 mark] 6 (a) (iv) Suggest why this harmful effect had NOT been detected during clinical drug trials on thalidomide. [1 mark] [Turn over]

28 6 (b) Using a recreational drug may cause a person to become dependent on the drug. 6 (b) (i) What happens in the body to make someone dependent on a drug? [1 mark]

29 BLANK PAGE [Turn over]

30 6 (b) (ii) Doctors rated different recreational drugs according to how dependent users had become on them. FIGURE 4 shows the results. FIGURE 4 3. 0 2. 5 2. 0 Increasing dependence 1. 5 1. 0 0. 5 0. 0 KEY Class A Class B Class C Unclassified H C L E B A Ca G AS N Al K Drug KEY H = Heroin C = Cocaine L = LSD E = Ecstasy B = Barbiturate A = Amphetamine Ca = Cannabis G = GBH AS = Anabolic steroids N = Nicotine Al = Alcohol K = Khat

31 It is illegal (against the law) to take Class A, B or C drugs. Unclassified drugs are legal. Some people think that some legal drugs should be made illegal. What evidence is there in FIGURE 4 to support this view? [2 marks] [Turn over]

32 6 (b) (iii) Suggest ONE other piece of information about legal drugs that would need to be considered before the classification of these drugs was changed. [1 mark] 8

33 7 FIGURE 5 shows: Phiomia, an ancestor of elephants a modern African elephant. Phiomia lived about 35 million years ago. FIGURE 5 Long nose Phiomia African elephant Trunk [Turn over]

34 Both Phiomia and the African elephant reach up into trees to get leaves. In the 1800s, Darwin and Lamarck had different theories about how the long nose of Phiomia evolved into the trunk of the African elephant. 7 (a) (i) Use Darwin s theory of natural selection to explain how the elephant s trunk evolved. [4 marks]

35 [Turn over]

36 7 (a) (ii) Lamarck s theory is different from Darwin s theory. Use Lamarck s theory to explain how the elephant s trunk evolved. [2 marks]

37 7 (b) (i) In the 1800s, many scientists could not decide whether Lamarck s theory or Darwin s theory was the right one. Give TWO reasons why. [2 marks] 1 2 [Turn over]

38 7 (b) (ii) Before the 1800s, many people had a different idea to explain where all the living things on Earth came from. What idea was this? [1 mark] 9

39 BLANK PAGE [Turn over]

40 8 Read the information. Insects can be both useful and harmful to crop plants. Insects such as bees pollinate the flowers of some crop plants. Pollination is needed for successful sexual reproduction of crop plants. Some insects eat crops and other insects eat the insects that eat crops. Corn borers are insects that eat maize plants. A toxin produced by the bacterium Bacillus thuringiensis kills insects. Scientists grow Bacillus thuringiensis in large containers. The toxin is collected from the containers and is sprayed over maize crops to kill corn borers.

41 A company has developed genetically modified (GM) maize plants. GM maize plants contain a gene from Bacillus thuringiensis. This gene changes the GM maize plants so that they produce the toxin. 8 (a) Describe how scientists can transfer the gene from Bacillus thuringiensis to maize plants. [3 marks] [Turn over]

42 8 (b) Would you advise farmers to grow GM maize plants? [4 marks] Justify your answer by giving advantages and disadvantages of growing GM maize plants. Use the information on pages 40 and 41 and your own knowledge to help you.

43 7 END OF QUESTIONS

BLANK PAGE 44

45 BLANK PAGE For Examiner s Use Examiner s Initials Question Mark 1 2 3 4 5 6 7 8 TOTAL

46 BLANK PAGE Acknowledgement of copyright-holders and publishers Permission to reproduce all copyright material has been applied for. In some cases, efforts to contact copyright-holders have been unsuccessful and AQA will be happy to rectify any omissions of acknowledgements in future papers if notified. Question 7: Figure 5: Getty Images Copyright 2014 AQA and its licensors. All rights reserved. G/KL/109316/Jun14/BL1HP-A3/E3