Technical Bulletin 12

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Revalor -S (trenbolone acetate + estradiol) Technical Bulletin 12 Revalor Implant Strategies W. Nichols, Ph.D., D. Brister, D.V.M., B. Burdett, D.V.M., J.P. Hutcheson, Ph.D., S. Nordstrom, D.V.M., C.D. Reinhardt, Ph.D., T. Shelton, D.V.M., and H. Newcomb, D.V.M. Steer Implant Strategies I. All-Around Implant Program - Steers Excellent performance in terms of average daily gain (ADG) and feed efficiency (F/G). Minimal to no quality grade reduction as long as cattle are finished to their physiological/biological end-points. Single implant steers to 130 days Initial Implant 80-130 days Slaughter Reimplant steers 130-170 days Initial Implant 60-80 days Reimplant 70-90 days Slaughter REVALOR-IS REVALOR-IS Reimplant steers 170-230 days Initial Implant 80-110 days Reimplant 90-120 days Slaughter REVALOR-IS Reimplant steers greater than 230 days on feed Initial Implant 70-100 d Reimplant 70-100 d Reimplant 90-120 d Slaughter RALGRO or REVALOR-IS SYNOVEX -C II. Special-Aggressive Implant Program - Steers Superior performance in terms of average daily gain (ADG) and feed efficiency (F/G) is the main goal. Heavier weights will need to be achieved to minimize grade reduction. Single implant steers to 130 days Initial Implant 80-130 days Slaughter Reimplant steers 130-230 days Initial Implant 60-110 days Reimplant 70-120 days Slaughter Reimplant steers greater than 230 days on feed Initial Implant 70-100 d Reimplant 70-100 d Reimplant 90-120 d Slaughter REVALOR-IS or

III. All-Around Implant Program - Heifers Excellent performance in terms of average daily gain (ADG) and feed efficiency (F/G) is the main goal. Minimal to no quality grade reduction as long as cattle are finished to their physiological/biological end-points. Single implant heifers to 130 days Initial Implant 80-130 days Slaughter REVALOR-H Reimplant heifers 130-240 days Initial Implant 60-110 days Reimplant 70-120 days Slaughter REVALOR-IH REVALOR-H or FINAPLIX-H Reimplant Heifers greater than 230 days on feed Initial Implant 70-100 d Reimplant 70-100 d Reimplant 90-120 d Slaughter RALGRO or REVALOR-IH REVALOR-H or SYNOVEX-C FINAPLIX-H * Finaplix-H must be utilized in conjunction with MGA (Melengestrol acetate). Revalor-IH and Revalor-H can be used with or without MGA. IV. Special-Aggressive Implant Program - Heifers Superior performance in terms of average daily gain (ADG) and feed efficiency (F/G) is the main goal. Heavier weights will need to be achieved to minimize grade reduction. Single implant heifers to 130 days Initial Implant 80-130 days Slaughter Reimplant heifers 130-170 days Initial Implant 60-80 days Reimplant 70-90 days Slaughter REVALOR-IH Reimplant heifers 170-230 days Initial Implant 80-110 days Reimplant 90-120 days Slaughter REVALOR-H Reimplant Heifers greater than 230 days on feed Initial Implant 70-100 d Reimplant 70-100 d Reimplant 90-120d Slaughter RALGRO or REVALOR-H SYNOVEX-C

Implant Strategies All the above implant strategies give you some leeway in marketing cattle. Example: A terminal Revalor-S is mostly utilized 100 days from slaughter. This gives you the ability to market cattle 20 days earlier than expected and as much as 30 days longer than expected, i.e. 170 day cattle can be marketed at 150 or 200 days. There are some trade-offs that we need to be aware of, i.e. 150 day cattle will have better ADG and F/G simply because we are selling them somewhat green, the 200-day cattle will have more marbling, maybe higher dressing %, more weight, and less ADG and F/G simply because we are selling them over-finished. EXAMPLE: Steer All Around Implanting Strategies DOF Initial Day Reimp Day Reimp Terminal 130 or less Revalor-S None None 140 Revalor-IS Day 70 Revalor-IS 150 Revalor-IS Day 70 Revalor-IS 160 Revalor-IS Day 70 Revalor-IS 170 Revalor-IS Day 70 Revalor-S 180 Revalor-IS Day 80 Revalor-S 190 Revalor-IS Day 90 Revalor-S 200 Revalor-IS Day 100 Revalor-S 210 Revalor-IS Day 100 Revalor-S 220 Revalor-IS Day 110 Revalor-S 230 Revalor-IS Day 110 Revalor-S 240 Ralgro Day 40 = Rev-IS Day 140 = Revalor-S EXAMPLE: Heifer All Around Implanting Strategies DOF Initial Day Reimp Day Reimp Terminal 130 or less Revalor-H None None 140 Revalor-IH Day 50 Revalor-H or Fin-H 150 Revalor-IH Day 50 Revalor-H or Fin-H 160 Revalor-IH Day 60 Revalor-H or Fin-H 170 Revalor-IH Day 70 Revalor-H or Fin-H 180 Revalor-IH Day 80 Revalor-H or Fin-H 190 Revalor-IH Day 90 Revalor-H or Fin-H 200 Revalor-IH Day 100 Revalor-H or Fin-H 210 Revalor-IH Day 100 Revalor-H or Fin-H 220 Revalor-IH Day 110 Revalor-H or Fin-H 230 Revalor-IH Day 110 Revalor-H or Fin-H 240 Ralgro Day 40 = Rev-IH Day 140 = Revalor-H or Fin-H During times of low ration costs and fair live cattle prices we can feed cattle a long time and cost of gain rarely exceeds breakeven. We can be aggressive in our feeding and cattle management as well as our implant programs. Conversely, when ration costs become expensive and live cattle prices are low, we will adjust the implant strategies to finish cattle at lighter weights and less time on feed (figure 1). The spread between choice and select carcasses can be a concern when the difference in dollars/cwt is very high. If selling on a grid that has premiums for marbling then this aspect becomes important and needs to be taken into account as well. However, finishing cattle to the correct weight will usually negate any marbling differences. As an example; figure 1 depicts low feed-low spread, which would indicate that we would want to feed for average grading and maximum weight. We can use an aggressive implant strategy in this economic example. Simply because we are going to feed to heavier weights to take advantage of the low feed costs and the heavier weights will help negate any negative marbling effects.

Do not just look at days on feed to determine when cattle are ready for slaughter. Let the cattle tell you when they are finished. Look at the cattle body composition and feed records. A 700 wt. animal, is not a 700 wt. animal, is not a 700 wt. animal. Adjust days on feed based on animal type, body conformation, and body composition. In addition, analyze carcass data to see if the cattle are achieving the correct end-points of production. If the closeouts have virtually all YG 1 & 2 s with very little YG3 s and no 4 s, then in general, the cattle are too light or green to achieve their genetic potential to marble. The cattle need a percentage of YG3 s to allow them to achieve their genetic potential to marble (on the average), as well as, reach a final end weight that allows the cattle to work, both from a carcass perspective and a live perspective. Figure 2 illustrates, as an example, cattle implanted differently and the final end-weights, which are needed to achieve an empty body fat (EBF) percentage of 28.6% (Guiroy, et al. 2002, submitted JAS). Research has indicated that an EBF of 28.6% is required for cattle to reach low choice marbling. Figure 1. A grid utilizing feed costs and choice/select spread for implant decisions* Cattle Selection High Feed - High Spread High Feed - Low Spread Low Feed - High Spread Low Feed - Low Spread Average Grading Maximum wt. Maximum Implant Buy for Growth Maximize performance Maximum Implant Maximum Grading Minimum weight Implant Cattle Type Dependent Average Grading Maximum YG Maximum wt. Maximum Implant? Schematic developed by M. Hubbert, Ganado Research, Arroyo Seco, NM Feed = Feed costs either high or low Spread = Dollars/cwt difference between choice and select carcasses Figure 2. Growth curve graph depicting finished weights of cattle that are implanted differently Implants Change the Growth Curve 40 35 30 25 20 15 10 5 0 800 1100 1165 1230 1265 28.6% EBF Low Choice No Implant 1 Implant 2 Implants

Implanting changes the growth curve upward to a higher level. In other words when we implant cattle that are a frame score 5, we now change their growth to mimic a frame score 6-7 (figure 3). The cattle will now need to be heavier to reach their genetic physiological/biological maturity. Figure 4 depicts the amount of EBF needed for cattle to grade standard, select, low choice, or mid-choice. On the average if we sell cattle that have less than 28% EBF, they will not exhibit enough finish to reach a USDA quality grade of low choice. The majority of cattle need to have 28.5-29.5% EBF in order to grade to their genetic potential. Therefore, all these factors need to be taken into consideration when choosing an effective implant strategy, i.e. feed costs, animal costs, quality grade, genetics, economic advantages of weight (live & carcass), production goals, and carcass goals. There are trade-offs to all the above and implants can help you achieve your goals and benefit you economically in all circumstances. Figure 3. Graph depicting the weight at which a certain frame score animal must reach in order to be at 28% EBF Weight (lb.) at 28% fat Frame Size 1 2 3 4 5 6 7 8 9 Steer 882 954 1029 1102 1175 1250 1322 1395 1470 Heifer 705 763 824 882 939 1001 1058 1115 1177 Figure 4. Graph depicting amount of EBF needed to reach a particular USDA quality grade (Guiroy et al. 2001, JAS). 34 Relationship of empty body fat to Quality Grade (total of 1,355 animals) Empty body fat, % 32 30 28 26 24 22 20 Standard, 21.1% EBF Select, 26.2% EBF Mid Choice, 29.9% EBF Low Choice, 28.6% EBF 3 3.5 4 4.5 5 5.5 6 6.5 7 7.5 8 8.5 9 9.5 10 Quality Grade

Implant Dosage Comparison Product Number of Amount of Amount of pellets trenbolone acetate estradiol Revalor-200 10 200 mg 20 mg Revalor-H 7 140 mg 14 mg Revalor-S 6 120 mg 24 mg Revalor-IS 4 80 mg 16 mg Revalor-IH 4 80 mg 8 mg Revalor-G 2 40 mg 8 mg Finaplix-H 10 200 mg 29160 Intervet Lane P.O. Box 318 Millsboro, Delaware 19966 www.intervetusa.com www.revalor.com 800.441.8272 2005, Intervet Inc. Part #: BV-REV-64619 MAG 07/05 Revalor and Finaplix are registered trademarks of Intervet Inc. or an affiliate Ralgro is a registered trademark of Schering Plough Animal Health Synovex is a registered trademark of Fort Dodge Animal Health, Inc.