easy. HPLC has never been so Agilent 1120 Compact LC Our measure is your success.

easy. HPLC has never been so Agilent 1120 Compact LC Our measure is your success.

Introducing the Agilent 1120 Compact LC Simply a better value. Is your lab looking for better, more reproducible results for all your standard HPLC analyses, run after run and day after day? Are you looking for an affordable, high quality solution that maximizes uptime, minimizes maintenance and provides the highest return on your investment? Here s some good news: the new 1120 Compact LC from Agilent. Now any lab can take advantage of Agilent s unmatched combination of advanced instrumentation, versatile software and application-matched columns and consumables. This robust new LC solution is designed to optimize performance, while minimizing complexity. And because it s from Agilent, it gives you the proven quality and performance you expect from the industry leader, in your choice of five easy to own, integrated, all-in-one configurations. Easy to learn and use for all users. With simple, intuitive Agilent EZChrom Elite Compact software and built-in self-diagnostics, the 1120 Compact LC is easy to operate and easy to maintain. Because every system is thoroughly tested in its final configuration before shipping, startup is fast and trouble-free. Right out of the box, even inexperienced or infrequent users can quickly master the system and produce first-rate results. Extraordinary results in a system optimized for everyday productivity. Run-after-run, day-after-day reproducibility. Exceptional accuracy. Superior precision. For all your routine applications including those that must comply with regulatory requirements the 1120 Compact LC offers uncompromising LC performance. Industry-leading quality and long-life Agilent reliability. Why settle for good enough, when you can invest in quality? With a 30-year history of success and an installed base of more than 60,000 LC systems, Agilent has earned a worldwide reputation for reliability and uptime under the most demanding operating conditions. EZChrom Elite Compact software makes it easy for all your users to set up and operate the system. Absorbance [mau] 600 400 200 0 1 2 Peak % RSD RT % RSD Area 1 2 3 4 0.05 0.08 0.09 0.09 0.22 0.30 0.19 0.09 0 1 2 3 4 5 6 7 8 9 10 11 Time [min] Excellent reproducibility of retention times and areas from six repetitive isocratic analyses of a standard sample with 3 µl injection volume. 3 4 2

Agilent s 1120 Compact LC delivers the performance you are looking for and reliability you can count on as well as today s lowest cost of ownership! A simply perfect choice for labs like yours. The Agilent 1120 Compact LC was developed specifically to address the needs of small- to medium-sized labs that are mainly concerned with routine analyses using standard HPLC methods. In keeping with its mission, the system delivers all the performance needed to meet stringent regulatory demands while setting new standards for compactness, ease of operation and serviceability. To learn more about the Agilent 1120 Compact LC, visit www.agilent.com/chem/1120 3

Simply more in tune with your lab s needs. Take a close look at the Agilent 1120 Compact LC and you ll find everything you need for first-class results and rewarding day-after-day productivity. And, because you re too busy to worry about complicated features your lab is unlikely to use, you ll be pleased to find there s nothing there you don t need. Five standard configurations to fit your LC workflow Isocratic Configurations Gradient Configurations Isocratic Pump Isocratic Pump Gradient Pump Gradient Pump Gradient Pump Manual Injector Autosampler Manual Injector Manual Injector Autosampler Column Oven Column Oven Column Oven Agilent s LC detectors are fully compatible with the 1120 Compact LC. Additional external detection choices include: Refractive Index (RID) Fluorescence (FLD) Evaporative Light Scattering (ELSD) Solvent delivery The optimized design of the pumping module used in the Agilent 1120 LC ensures stable, virtually pulse-free solvent flow up to 10 ml/min. Servo-controlled, dual floating pistons enable variable stroke volume optimized for the selected flow rate, and keeps maintenance to a minimum. Choose from different configurations, including either an isocratic pump or a gradient pump with up to two solvents and integrated two-channel degasser. Degasser The gradient pump includes an integrated dual-channel degasser with continuous vacuum using Teflon AF technology, which provides low internal volumes of 1.5 ml per channel. The degasser eliminates baseline fluctuations and shortens equilibration times. Pump options Automated solvent selection valve for gradient pump combines two-out-of-four solvents for gradient formation or for column flushing with different solvents. Continuous seal wash kit to prevent corrosion for applications running buffer solutions with high salt concentrations greater than 0.1 M. Gradient pump and integrated degasser 4

Manual injector An easy to use, easy to maintain solution for low throughput sampling, the manual injector includes a long-life Rheodyne 2-position, 6-port sample injection valve and standard 20 µl loop. Front access to the valve facilitates easy sample injection and straightforward exchange of sample loops. Autosampler The integrated autosampler is designed for reliability, safety, and easy maintenance, and facilitates reliable injections from 0.1 to 100 µl. The unit delivers high precision as well as excellent linearity over a wide volume range. The autosampler s flow-through design ensures that there is no loss of sample; the entire sample drawn from the vial is injected. The standard configuration offers a sample capacity of 100 2-mL vials; alternatively, two half-trays each with 40 2-mL vials or 15 6-mL vials can be used. Column oven The 1120 Compact LC's available column oven houses a single column, and provides accurate, stable column temperature from 10 degrees above ambient to 60 C, for applications where retention time reproducibility and separation quality improve above ambient temperatures. Variable wavelength detector Featuring simplified optics for high sensitivity, low baseline drift and wide linear range, Agilent s variable wavelength detector not only lowers your detection limits; it lowers your cost of ownership with easy front access for fast lamp and flow cell replacement. Manual injector Autosampler Column oven Variable wavelength detector Absorbance [mau] 45 40 35 30 25 20 15 10 5 0 5.154 5.309 Impurities 8.803 Ibuprofen 11.686 Absorbance [mau] 40 30 20 10 0 1 2 4 3 5 6 7 8 9 Peak Compound 1 Metamitron 2 Chloridazone 3 Cyanazine 4 Simazine 5 Prometryn 6 Diuron 7 Propazine 8 Terbuthylazine 9 Chlortoluron 0 1 2 3 4 5 6 7 8 9 10 11 12 13 Time [min] Analysis of a pharmaceutical preparation, showing the active ingredient ibuprofen and three earlier-eluting impurities. 0 2 4 6 8 10 12 14 Time [min] Trace analysis of pesticide residues, showing a limit of detection (LOD) of less than 100 pg. The relative standard deviation is less than 0.08 % for retention times and less than 0.5 % for areas. To learn more about the Agilent 1120 Compact LC, visit www.agilent.com/chem/1120 5

Simply easier to learn, to use and to live with. A complete, integrated software solution With the bundled EZChrom Elite Compact software, it s easy to put all of the capabilities of the 1120 Compact LC to work in your lab. A fast, powerful chromatography data system, EZChrom Elite Compact provides full control of two 1120 Compact LCs from a single PC. EZChrom Elite Compact includes comprehensive data processing, flexible reporting and the full range of capabilities you would expect from a modern chromatography work station. Regulatory compliance made easy. EZChrom Elite Compact provides comprehensive tools to help you address all the requirements of GLP/GMP and 21 CFR Part 11 compliance. With built-in audit trails, multi-user login security, user permissions, and electronic signatures, the software made easy for your laboratory to operate in any regulated environment. Quick access to common tasks. View instrument status, current data and run queue on a single screen and perform a run with just a couple of mouse clicks. Scalable from a single user to a whole enterprise. As a scalable part of the Agilent informatics portfolio, your EZChrom Elite Compact software can grow as your lab grows. Upgrade to EZChrom Elite Workstation and add control for over 330 chromatographic components from more than 25 vendors. Expand further to full client-server deployment, or all the way to Agilent s enterprise-wide OpenLAB solution. No matter how your lab s needs evolve, your data, methods, sequences and reports will still be readable. And, because the user interface is the same across the full product line, you won t have to retrain your operators. From EZChrom Elite Compact to Workstation to Client/Server, EZChrom Elite software can be easily scaled up to meet the changing needs of a growing lab. 6

Agilent columns and supplies an extra measure of reliability and confidence. Whatever your lab is analyzing, every method requires day-to-day reproducibility and superior reliability. To deliver optimal performance with all your samples and mobile phase, the Agilent ZORBAX Eclipse Plus columns give you the performance and consistency you're looking for. These columns deliver excellent peak shape under a wide range of operating conditions for the highest quality, reproducible results. Try the Eclipse Plus C18 column included with your 1120 Compact LC. You'll appreciate its superior qualitative and quantitative performance. And if you need other columns the complete ZORBAX product line will have a choice for your application. ZORBAX columns and Agilent supplies for your new compact LC the products you need to achieve peak productivity day after day, and year after year. Maximize your uptime with Agilent s customerenabled service and support features. The 1120 Compact LC s integrated hardware and software design features provide a completely new level of operational simplicity. There s a guided system set-up so that you can get your new 1120 Compact LC up and running without having to schedule a visit by an Agilent service representative. Lab Monitor & Diagnostic Software alerts you to problems before they happen. Now you can detect instrument problems before they occur and schedule a convenient time to solve the problem without it impacting your analysis. This is facilitated by an easy-to-use package included in your system, Lab Monitor and Diagnostics software, that continuously monitors your instrument. From a lab-at-a-glance screen that displays a snapshot of all connected 1120 Compact LC instruments, to guided diagnostics tests and easy to perform maintenance routines, to a built-in suite of user information and help, Lab Monitor and Diagnostics software provides all the information a user needs in one convenient place at one time thus enabling you to maximize your instrument s efficiency and productivity. Of course, Agilent s world class customer service engineers and certified support partners are available to provide a full range of Agilent services, including installation, familiarization, training, maintenance, contractual repair, and regulatory compliance support. To learn more about the Agilent 1120 Compact LC, visit www.agilent.com/chem/1120 7

The Agilent Value Promise 10 years of guaranteed value In addition to continually evolving products, we offer something else unique to the industry our 10-year value guarantee. The Agilent Value Promise guarantees you at least 10 years of instrument use from your date of purchase, or we will credit you with the residual value of that system toward an upgraded model. Not only does Agilent ensure a safe purchase now, we help ensure your investment is as valuable to you in the long run. The Agilent Service Guarantee Should your Agilent instrument require service while covered by an Agilent service agreement, we guarantee repair or we will replace your instrument for free. No other manufacturer or service provider offers this level of commitment to keeping your laboratory running at maximum productivity. For more information Learn more: www.agilent.com/chem/1120 Buy online: www.agilent.com/chem/store Find an Agilent customer center in your country: www.agilent.com/chem/contactus Contact us: agilent_inquiries@agilent.com Agilent Technologies, Inc. 2008 Published March 1, 2008 5989-7372EN