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Mass Cytometry Comprehensive Publications 2012 Behbehani, G.K., et al. Single-cell mass cytometry adapted to measurements of the cell cycle. Cytometry A 81 (7): 552-566, 2012. Bendall, S.C., et al. A deep profiler's guide to cytometry. Trends Immunol 33 (7): 323-332, 2012. Bendall, S.C., et al. From single cells to deep phenotypes in cancer. Nat Biotechnol 30 (7): 639-647, 2012. Bodenmiller, B., et al. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nat Biotechnol (on-line August 19, 2012). DOI 10.1038/nbt2317. Fienberg, H.G., et al. A platinum-based covalent viability reagent for single-cell mass cytometry. Cytometry A 81 (6): 467-475, 2012. Liang, Y., et al. The release and extraction of lanthanide ions from metalencoded poly (styrene-co-methacrylic acid) microspheres. Polymer 2012 (53): 998-1004, 2012. Lu, Y., et al. Effect of pendant group structure on the hydrolytic stability of polyaspartamide polymers under physiological conditions. Biomacromolecules 13 (5): 1296-1306, 2012. Newell, E.W., et al. Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity 36 (1): 142-152, 2012. Wang, L., et al. Human CD4(+) lymphocytes for antigen quantification: Characterization using conventional flow cytometry and mass cytometry. Cytometry A 81 (7): 567-575, 2012. 2011 Abdelrahman, A.I., et al. Surface Functionalization Methods to Enhance Bioconjugation in Metal-Labeled Polystyrene Particles. Macromolecules 44 (12): 4801-4813, 2011. Bendall, S.C., et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 332 (6030): 687-696, 2011.

Lathia, U.S., et al. Multiplexed protease assays using element-tagged substrates. Anal Biochem 408 (1): 157-159, 2011. Leipold, M.D., et al. Development of mass cytometry methods for bacterial discrimination. Anal Biochem 419 (1): 1-8, 2011. Liang, Y., et al. The synthesis and characterization of lanthanide-encoded poly(styrene-co-methacrylic acid) microspheres. Polymer 52 5040-5052, 2011. Lin, W., et al. Synthesis and mass cytometric analysis of lanthanide-encoded polyelectrolyte microgels. Langmuir 27 (11): 7265-7275, 2011. Majonis, D., et al. Curious results with palladium- and platinum-carrying polymers in mass cytometry bioassays and an unexpected application as a dead cell stain. Biomacromolecules 12 (11): 3997-4010, 2011. Qiu, P., et al. Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nat Biotechnol 29 (10): 886-891, 2011. 2010 Abdelrahman, A.I., et al. Metal-Containing Polystyrene Beads as Standards for Mass Cytometry. J Anal At Spectrom 25 (3): 260-268, 2010. Berger, S., et al. Hybrid nanogels by encapsulation of lanthanide-doped LaF3 nanoparticles as elemental tags for detection by atomic mass spectrometry. J Mater Chem 20 (24): 5141-5150, 2010. Lathia, U.S., et al. Development of inductively coupled plasma-mass spectrometry-based protease assays. Anal Biochem 398 (1): 93-98, 2010. Majonis, D., et al. Synthesis of a Functional Metal-Chelating Polymer and Steps toward Quantitative Mass Cytometry Bioassays. Anal Chem 2010. Ornatsky, O., et al. Highly multiparametric analysis by mass cytometry. J Immunol Methods 361 (1-2): 1-20, 2010. Thickett, S.C., et al. Bio-Functional, Lanthanide-Labeled Polymer Particles by Seeded Emulsion Polymerization and their Characterization by Novel ICP-MS Detection. J Anal At Spectrom 25 (3): 269-281, 2010.

2009 Abdelrahman, A.I., et al. Lanthanide-containing polymer microspheres by multiple-stage dispersion polymerization for highly multiplexed bioassays. J Am Chem Soc 131 (42): 15276-15283, 2009. AND ERRATUM. J Am Chem Soc 132: 2465, 2010. Bandura, D.R., et al. Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. Anal Chem 81 (16): 6813-6822, 2009. Leipold, M.D., et al. ICP-MS-based multiplex profiling of glycoproteins using lectins conjugated to lanthanide-chelating polymers. J Proteome Res 8 (2): 443-449, 2009. Pich, A., et al. The influence of PEG macromonomers on the size and properties of thermosensitive aqueous microgels. Colloid and polymer science 287 (3): 269-275, 2009. 2008 Ornatsky, O.I., et al. Development of analytical methods for multiplex bio-assay with inductively coupled plasma mass spectrometry. J Anal At Spectrom 23 (4): 463-469, 2008. Ornatsky, O.I., et al. Study of cell antigens and intracellular DNA by identification of element-containing labels and metallointercalators using inductively coupled plasma mass spectrometry. Anal Chem 80 (7): 2539-2547, 2008. Pich, A., et al. Biocompatible hybrid nanogels. Small 4 (12): 2171-2175, 2008. Razumienko, E., et al. Element-tagged immunoassay with ICP-MS detection: evaluation and comparison to conventional immunoassays. J Immunol Methods 336 (1): 56-63, 2008. Tanner, S.D., et al. Flow cytometer with mass spectrometer detection for massively multiplexed single-cell biomarker assay. Pure Appl. Chem. 80 (12): 2627-2641, 2008. 2002-2007 Baranov, V.I., et al. A sensitive and quantitative element-tagged immunoassay with ICPMS detection. Anal Chem 74 (7): 1629-1636, 2002. Baranov, V.I., et al. The potential for elemental analysis in biotechnology. J. Anal. At. Spectrom. 17 (9): 1148-1152, 2002.

Bandura, D.R., et al. Characterization of phosphorus content of biological samples by ICP-DRC-MS: potential tool for cancer research. J. Anal. At. Spectrom. 19 (1): 96-100, 2004. Lou, X., et al. Polymer-based elemental tags for sensitive bioassays. Angew Chem Int Ed Engl 46 (32): 6111-6114, 2007. Ornatsky, O., et al. Multiple cellular antigen detection by ICP-MS. J Immunol Methods 308 (1-2): 68-76, 2006. Ornatsky, O.I., et al. Messenger RNA Detection in Leukemia Cell lines by Novel Metal-Tagged in situ Hybridization using Inductively Coupled Plasma Mass Spectrometry. Translational Oncogenomics (1): 1-9, 2006. Quinn, Z.A., et al. Simultaneous determination of proteins using an elementtagged immunoassay coupled with ICP-MS detection. J. Anal. At. Spectrom. 17 (8): 892-896, 2002. Tanner, S.D., et al. Multiplex bio-assay with inductively coupled plasma mass spectrometry: Towards a massively multivariate single-cell technology. Spectrochim Acta Part B At Spectrosc. 62 (3): 188 195, 2007. Vancaeyzeele, C., et al. Lanthanide-containing polymer nanoparticles for biological tagging applications: nonspecific endocytosis and cell adhesion. J Am Chem Soc 129 (44): 13653-13660, 2007. Commentary 2012 de Souza, N. Improved single-cell methods are helping to unravel biological complexity. Nat Methods 9 (35): 2012. Chen, G., et al. Analyzing the phenotypic and functional complexity of lymphocytes using CyTOF (cytometry by time-of-flight). Cell Mol Immunol 9 (4): 322-323, 2012. 2011 Benoist, C., et al. Immunology. Flow cytometry, amped up. Science 332 (6030): 677-678, 2011. Doerr, A. A flow cytometry revolution. Nat Methods 8 (7): 531, 2011.

Cheung, R.K., et al. Screening: CyTOF-the next generation of cell detection. Nat Rev Rheumatol 7 (9): 502-503, 2011. Janes, M.R., et al. Next-generation flow cytometry. Nat Biotechnol 29 (7): 602-604, 2011. D V S S c i e n c e s, 6 3 9 N. P a s t o r i a A v e., S u n n y v a l e, C A 9 4 0 8 5-2917 h t t p : / / w w w. D V S s c i e n c e s. c o m T e l : + 1 8 5 5 - D V S - C Y T O E m a i l : s a l e s @ D V S s c i e n c e s. c o m