Biochemistry and Structural Biology (BSB) 2 May (Wed) 3 May (Thur) 4 May (Fri) 7 May (Mon) 8 May (Tue) Opening Miguel Teixeira BSB presentation Inês Pereira (9.45-10.00) Metals in Biology Miguel Teixeira (10.00-11.00) Introduction to spectroscopy Eurico Melo (11.30-12.30) Electron paramagnetic ressonance in Biology Miguel Teixeira (12.30-13.30) Protein structure Margarida Archer Protein and small molecule crystallography Isabel Bento (11.00-13.00) Raman spectroscopy: theoretical basis and applications Smilja Todorovic Protein folding and stability Cláudio Gomes (11.00-13.00) Nuclear Magnetic Resonance in Structural Biology David Turner/Pedro Lamosa NMR (cont.) David Turner/Pedro Lamosa Molecular mechanics/ dynamics of biomolecules Cláudio M. Soares Homology - detection and functional inference José Leal (IGC) Protein electrostatics António M. Baptista Protein structure prediction Cláudio M. Soares Energy transduction in respiratory systems* Paper discussion Manuela Pereira Andreia Fernandes How to interpret X-ray Crystallographic Data* Paper discussion Pedro Matias Carlos Frazão Hot topics in Protein Folding research* Guided paper discussion Cláudio Gomes Patrícia Faísca Anaerobic microorganisms: from proteins to applications* Inês Cardoso Pereira Ricardo Louro Catarina Paquete Molecular visualisation* Cláudio M. Soares António M. Baptista
Biomolecular Chemistry (BC) 9 May (Wed) 10 May (Thur) 11 May (Fri) 14 May (Mon) 15 May (Tue) BC Presentation Beatriz Royo Natural products isolation and asymmetric catalysis Christopher Maycock (9.45-11.15) (11.15-11.45) Organocatalysis: synthesis of novel catalysts Rita Ventura (11.45-13.15) Supramolecular chemistry: an overview Rita Delgado Metal based drugs Carlos C. Romão UV-Vis Spectroscopy Eurico Melo (9.30-11.30) (11.30-12.00) Atomic Force Microscopy Miguel Castanho (FC/UL) Radioisotopes and biomedical applications Isabel Santos (ITN) Radioisotopes and biomedical applications António Paulo (ITN) Hyperthermophiles as a source of new protein stabilizers Helena Santos Biological targets for prodrug strategy Ana Luísa Simplício Mass spectrometry* Ana Coelho Inc. visit to the lab Inorganic chemistry, biology and medicine* Paper discussion Beatriz Royo Patrícia Reis Equipment and methods in UV-Vis spectroscop*y Eurico Melo Visit to the lab Potentiometry with ionselective electrodes and cyclic voltametry Margarida Santos (IST) (14.30-16.30) Presentation of the PhD. projects by the students* (4+1min) Module Coordinators
Microbial Physiology and Pathogenesis (MPP) 16 May (Wed) 17 May (Thur) 18 May (Fri) 21 May (Mon) 22 May (Tue) MPP presentation Partitioning of the transcriptional space I Adriano Henriques (9.45-10.45) (10.45-11.15) Partitioning of the transcriptional space II Adriano Henriques (11.15-12.15) Transcriptional regulation: protein-dna interactions Isabel Sá-Nogueira (12.15-13.15) Introduction to bacterial stress* James Yates (14.30-15.30) Control of gene expression: the central role of RNA Cecilia Arraiano Metabolic networks and integration of metabolism Ana Rute Neves Bacterial stress* James Yates Microbial Survival To Nitrosative And Oxidative Stress Imposed By The Immune System Lígia Saraiva Surviving antibiotics: extensive changes in transcription profile induced by antibiotics Rita Sobral Introduction to posttranscriptional regulation* Karina Xavier Rita Sobral (14.30-15.30) Bacterial cell surface composition, metabolic pathways and role in microbial pathogenesis Immune mechanisms of host resistance or susceptibility to bacterial pathogens Manuel Vilanova (ICBAS) Post-transcriptional regulation.* Karina Xavier Rita Sobral Quorum-sensing and bacterial host relationship Karina Xavier Evolution of the microbial physiology - from food to disease Maria Fátima Lopes Enterococci from commensal to pathogenic bacteria Rosário Mato BIOENTREPRENEURSHIP Factors for Biomedical Research at the University Industry Interface Manuel Carrondo (IBET) (14:30-15:20) PHILOSOPHY OF SCIENCE Rigour as an ideal. A discussion of the philosophical pressupositions of the modern scientific project Marta Mendonça (FCSH/UNL) (16:00-17:30)
Cell and Developmental Biology (CDB) 23 May (Wed) 24 May (Thur) 25 May (Fri) 28 May (Mon) 29 May (Tue) CDB Presentation Cellular Organization of Genome Function (9.45-10.45) (10.45-11.15) Light Microscopy in Cell Biology Gabriel Martins (IGC) (11.15-12.15) 3D Live Cell Imaging Gabriel Martins (IGC) (12.15-13.15) Plant Secondary Metabolites C. Pinto Ricardo Growth and morphogenesis at the cellular level: ion dynamics and pollen tube growth Jose Feijó (IGC) Plant Cell Wall Phil Jackson Bacterial Cell Division Mariana Pinho CDB Journal club* Nuno Geraldo (11:00-13:00) A View at specific processes essential for vertebrate Development Moises Mallo (LA-IGC) Prokaryotic Development Adriano Henriques Limits and Applications of Electron Microscopy in the age of live imaging and molecular constructs Rui Malho (FC/UL) The Secretory Pathway Júlia Costa Signaling in Yeast under stress response Claudina R.Pousada Microscopy Viewing samples under the fluorescence microscope. Overview of different techniques to visualize genes and genomes* Ana Paula Santos Nuno Geraldo SOCIOLOGY OF SCIENCE The sociology of science: theory and empirical research (a brief overview and some recent studies) António Firmino da Costa (14.30-15.50) Science for the 21 st Century João Caraça (Fundação Calouste Gulbenkian) (16.00-17.20) Cell Cycle and Cell Division Mechanisms Alvaro Tavares (IGC) (14.30-15.30) (15.30-15.45) Telomeres and Cancer Miguel Godinho (IGC) (15.45-16.45) CDB Paper Presentations part I* CDB Paper presentations part II *
Biotechnology 30 May (Wed) 31 May (Thur) 1 June (Fri) 4 June (Mon) 5 June (Tue) Biotech Presentation Júlia Costa Main strategies and achievements in plant genetic engineering Margarida Oliveira (9.45-10.45) (10.45-11.15) Molecular pharming (11.15-12.15) Integrating protein science and technology: the laccase-study Lígia Martins (12.15-13.15) Animal cell culture Paula Alves Molecular biology of animal cells Ana Sofia Coroadinha From genes to biopharmaceuticals Manuel Carrondo Downstream processing for complex biopharmaceuticals Paula Alves Protein glycosylation Júlia Costa Recombinant human protein therapeutics: quality, safety, structural and approval aspects Harald Conradt Biosensors Abel Oliva Nutraceuticals Catarina Duarte Good Laboratory Practices Teresa Crespo Green solvents for separations Luis Paulo Rebelo Biocatalysis using green solvents Cristina Pereira Green technology in chemical engineering M. Nunes da Ponte Biological issues, technologies and ethics in plant genetic engineering* Demonstration. Group discussion. Célia Miguel Ana Sanchez Bioethics challenges and dilemmas for our times Paula Martinho da Silva (CNEV) (14.30-15.50) Fermentation and largescale production Class+visit pilot plant* António Cunha (16.00-17.30) Cell and Gene Therapy Technologies and Clinical applications*. Short presentation and discussion of papers. Ana Sofia Coroadinha Pedro Cruz Protein technologies from bacteria and yeast*. Lígia Saraiva Regina Menezes A Technological mix of Microbiology and Chemistry*. Discussion of papers Luís Paulo Rebelo José Nuno Lopes Cristina Pereira
Bioentrepreneurship 6 June (Wed) Alfama Early stage drug development in Portugal - the case of Alfama Nuno Arantes de Oliveira (11.00-11.50) GlycoThera (title) Harald Conradt Augusto Mateus (ISEG) (14:30) Bioentrepreneurship: a driver for the economic development Jaime Andrez (IAPMEI) (15:30)