Big Decisions: Using data and analytics to transform decisionmaking in Healthcare and Life Sciences

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Big Decisions: Using data and analytics to transform decisionmaking in Healthcare and Life Sciences Insights from s Big Decisions TM Research November 2016

s Global Data and Analytics Survey 2016: Big Decisions TM Why What Who Strategic decisions create value for an organization. Decision-makers are now face-to-face with an opportunity to learn from massive amounts of data. How can we apply data analytics to create greater value? What types of decisions will you need to make between now and 2020? What types of data and analytics do these decisions require? What is the role of machines in decision making? What s your ambition for improving decision speed and sophistication to make these decisions in your organization? 79% senior decision-makers (C- Level Executive or SVP / VP title) 58% of total Healthcare / Life Sciences based respondents had revenues of $1 billion last year 52% respondents are based in US 2

Top Healthcare and Pharma LS strategic decisions focus on developing /launching new products or services, developing partnerships and Investment in IT Which one of the following best describes this key strategic decision? Developing or launching new products or Entering new markets with existing Investment in IT Change to business operations Developing Partnerships Corporate restructuring or outsourcing Entering a new industry or starting a new Adjust product development to meet evolving risk needs of the market what areas of science to invest & how big Company will need to determine the appropriate allocation of resources towards R&D aligning with the evolving pressures around efficacy and economics. Investing in I.T. to improve access to information from previously difficult to access sources of data. Shrinking existing business Other Decision 0% 10% 20% 30% 40% 50% Healthcare Pharma LS Population Health strategy with multiple partners How to continue success in a highly regulated industry while maintaining value for our partners and customers. 3

Executives shared with the most anticipated changes to impact your sectors in the next 5 years Arrival of the baby boomers generation: older; more demanding; willing to pay for additional added value products in the Heath care sector Internet of things everything connected Regulatory changes in healthcare Significant increase in utilization of technology in treatment program. Use of apps to monitor recovery utilization of technology incorporation of new holistic non-traditional modalities for treatment Declining government reimbursement The movement to population health and more business shifting to risk Comparatively, Healthcare & Pharma LS expect to see more creative change with less status quo. The real difference to note is how Healthcare is anticipating radical game-changing events over the next 5 years. Whereas Pharma / LS estimates intermediating change with core activities threatened. 4

Obtaining market leadership will be a key motivator when it comes to strategic decision making Key strategic decision will be motivated by: Global Market Leadership Healthcare Market Leadership Pharma LS Market Leadership Between 2015 and 2020, change in my industry will likely be... A Need to Survive A Need to Survive Ability to Disrupt A Need to Survive Ability to Disrupt A Need to Survive Ability to Disrupt Healthcare s strategic decisions appear more in line with the global population, more motivated by desire for market leadership and a need to survive. Pharma LS s strategic decisions more motivated by desire for market leadership and ability to disrupt than other sectors. Radical (gamechanging everything up in the air) Intermediating (core activities threatened relationships fragile) Creative (stable core activities but new playing fields core Incremental (status quo preserved incremental progress) 24% 13% 16% 14% 25% 24% 19% 16% 19% Healthcare Pharma LS Global 42% 46% 42% 5

Majority do not identify as highly data driven Majority in Pharma / LS and Healthcare say they are not highly data driven.. Which of the following best describes decision-making in your organization (highly, somewhat or rarely data-driven? All Industries Combined 8% 39% 53% Pharma / LS 6% 45% 49% Healthcare 4% 39% 57% 0% 10% 20% 30% 40% 50% 60% Highly data-driven Somewhat data-driven Rarely data-driven *n = # of type of data-driven organization 6

Healthcare and Pharma / LS respondents said they mostly rely on descriptive and diagnostic analytics Only 17% (Pharma / LS) and 10% (Healthcare) said they use data to help them understand what should happen next and how (Prescriptive Analytics) Descriptive (What has happened?) 24% 28% 34% Diagnostic (Why did it happen?) 28% 31% 35% Predictive (What will/could happen?) 24% 24% 29% Prescriptive (What should happen and how?) 10% 13% 17% Don't know 2% 0% 1% 0% 5% 10% 15% 20% 25% 30% 35% 40% All Industries Combined Pharma / LS Healthcare *n = # of type of data-driven organization by type of analytical technique applied 7

Whereas across other industries, companies are using different principles to drive growth in their business models Examples Information Monetization Models Risk Prediction and Prevention Shifting from reacting to risks to predicting and preventing risks Illustrative Health Care Applications Customizing interventions with clinical, wearables, and patient behavioral data Decision Enhancement Simulation Disruptive Products and Services Hyper Targeted Offers Information Driven Markets Targeting critical decision makers with more timely insights Monitoring and simulating operations to improve performance Creating massive unstructured and structured data sets to deliver new, disruptive products and services in value chains or ecosystems Aggregating and analyzing massive amounts of customer data to enable real-time hyper-targeted offers Creating markets that didn t exist using real-time data exchange to better match buyers and sellers Accelerating clinical trials by monitoring site efficiency, enrollment or patient drop-out Simulating demand scenarios and supply chain disruptions to understand impact of demand fluctuation or disruptions on ability to deliver product to patient Improving targeting by integrating largescale genomic data with clinical data to understand disease biology Enhancing patient engagement and product compliance by integrating demographics, social and clinical data Advance precision medicine by building research and clinical data collaborations with providers to better interpret trial results 8

Organizations are at different levels of maturity in decision making speed and sophistication to create value s Decision Sophistication & Speed Matrix (n=# of decisions) Sophistication Analytics maturity Data breadth & depth Decision approach Increasing sophistication should simplify, not increase complexity Speed Low High Accelerated Agility Cover the Basics Low Sophistication Intelligence in the Moment Master the Chess Moves High Speed Time to answer question Time to decide action Time to implement / measure Speed is as much about structure as it is about data & analytics 9

Data Speed and Sophistication in the Healthcare & Pharma LS: Where they think they ARE versus where they WANT TO BE Top Strategic Decision for both Healthcare and Pharma LS: Developing or launching new products or services Accelerated Agility Healthcare Healthcare Intelligence in the Moment Accelerated Agility Pharma LS Intelligence in the Moment Speed Speed Speed Cover the Basics Master the Chess Moves Cover the Basics Master the Chess Moves Sophistication Sophistication Existing Where it needs to be in 2020 Existing Where it needs to be in 2020 Consistent themes across both Pharma LS & Healthcare is the wide spread confidence/lack of confidence in the current state of their organizations, in respect to both data speed and sophistication. However, there is strong consensus to compete in Developing or Launching New Products or Services both will need to improvements. 10

Increasing speed and sophistication a few examples Driverless & Electric Vehicles Speed Low High Accelerated Agility Cover the Basics Low Leading US multispecialty academic hospital Optimizing inpatient bed capacity Regional Blue Cross Blue Shield Improving STAR ratings and reimbursements US biopharma Ensuring 340B compliance through data-driven audits Sophistication $20B US biopharma Personalizing patient interventions and outcomes Leading global biopharma Improving oversight of CRO site operations $50B global biotech Optimizing clinical trial design with biomarker analytics High Intelligence in the Moment Leading cancer care and research institution Using unstructured data Master the Chess Moves 11

Anticipated limitations: Leadership courage and Budgetary considerations are most often cited Pharma LS: In absolute terms, leadership courage, available resources / manpower and operational capacity are the most anticipated limitations. Compared with Healthcare, where respondents are far less concerned with available resources/manpower and are far more concerned with budgetary constraints followed by leadership courage, the latter being a consistent top concern across our global benchmark 12

Improved decision making with Data & Analytics requires overcoming common decision traps Decision Trap Description Anchoring Trap Overconfidence Trap Disproportionat e weight to first information received Overestimate judgment and predictions; remember success, forget errors Status-Quo /Sunk Cost Trap Perpetuates the current state or past decisions; risk-averse mindset Confirming- Evidence Trap (Confirmation Bias) Seek supporting information; avoid contradictory information Framing Trap How a problem is framed influences the decisions made Availability Bias (Rush to Solve) Rely on information that is most readily available Maximize D&A Impact Show options & present range of facts Use gaming Simulate and quantify risk of status quo Leverage benchmarks Use different framings (competitor, customer, employee) Create Comprehensive Decision Support Systems 13

Effectively making decisions with D&A requires tailoring the approach and benefits to the decision makers style Charismatic Controller Follower Skeptic Thinker The Charismatic Easily enthralled, but uses balanced approach Emphasize bottom line results The Controller Unemotional and analytical Only implements own ideas The Follower Relies on others past decisions to make current choices Late adopter The Skeptic Decisions made on gut feeling Challenges every data point Applying D&A Co-present with trusted advisor Emphasize credibility of D&A data sources Arguments grounded in reality Presentation capitulates to skeptic leaders ego The Thinker Toughest to persuade Risk-averse Attention to detail 14

Key findings from Big Decisions survey More organizations are taking a data-driven approach to making strategic decisions. Are you? Data-driven organizations are using machines to de-risk their decisions. Executives have great ambition to increase decision speed and sophistication, but everyone expects to fall short of their ambition. What s your expectation? Organizations face many limitations in their decision making, however data and the ability to analyze data are the least of their concerns. Highly data-driven companies are three times more likely to report significant improvement in decision making, but only 1 in 3 executives say their organization is highly data-driven. Where will you be? 15

For more information, contact: Patrick Figgis Global Leader, Health Tel: +44 207 804 7718 patrick.figgis@pwc.com Dean Arnold Europe, Middle East, Africa Leader, Health Industries Tel: +44 (0) 20 721 38270 dean.c.arnold@pwc.com Kelly Barnes Asia Pacific, Americas Leader, Health Industries and Global Health Industries Consulting Leader Tel: +1 (214) 754 5172 kelly.a.barnes@pwc.com 16

Q&A For more information visit, www.pwc.com/bigdecisions This publication has been prepared for general guidance on matters of interest only, and does not constitute professional advice. You should not act upon the information contained in this publication without obtaining specific professional advice. No representation or warranty (express or implied) is given as to the accuracy or completeness of the information contained in this publication, and, to the extent permitted by law, PricewaterhouseCoopers LLP, its members, employees and agents do not accept or assume any liability, responsibility or duty of care for any consequences of you or anyone else acting, or refraining to act, in reliance on the information contained in this publication or for any decision based on it. 2016 PricewaterhouseCoopers LLP. All rights reserved. In this document, refers to PricewaterhouseCoopers LLP which is a member firm of PricewaterhouseCoopers International Limited, each member firm of which is a separate legal entity. 17