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Information AND SPONSORSHIP PACK The European Society of Gene and Cell Therapy (ESGCT) is a non-profit organisation committed to supporting the advance of basic and translational research and clinical applications of gene and cell therapy. The ESGCT Board is composed of highly respected and successful researchers representing a broad range of European Countries.

What we do ESGCT has a growing membership including students, scientists, clinicians, ethicists and regulators from both academia and industry. We engage with our members to facilitate education and exchange new knowledge. We promote the field through: an annual congress that takes place each year in different European locations awards that recognise and celebrate the brightest researchers representation on decision-making committees at the highest levels in Europe public engagement days where members of the public, schools and patients are invited to join in discussion and debate about gene and cell therapy 2 www.esgct.eu

A global audience The ESGCT annual congress attracts more than 1,000 delegates from across the world, making it the largest forum for gene and cell therapy in Europe. We work hard to create an engaging congress and the numbers suggest it is working: Abstract submission grows by at least 10% annually Delegate numbers grow by at least 10% annually; more than 60% of delegates return every year We have seen a large increase in interest from industry over the past three years and 85% of our exhibitors and sponsors return every year 85% of delegates would, given the opportunity, attend another congress More than 90% of delegates would recommend the ESGCT annual congress to colleagues 3 www.esgct.eu

Developing talent We are focused on nurturing the next generation of leaders. We provide incentives for students to participate, including subsidised registration fees and free yearly membership as part of their registration to the congress. 4 www.esgct.eu

Participation United Kingdom 6% North America 6% Scandinavia 4% Rest of World 4% Asia 6% France 10% Eastern Europe 1% Spain 1% Germany 11% Local Society Country 30% Rest of Europe 21% The top three reasons delegates are attracted to our annual congresses: Quality of overall scientific programme Location and price Networking opportunities ESGCT provided an excellent opportunity to see cutting edge products and services for our work. We ended up contracting one of the exhibitors for half a million worth of product. 5 www.esgct.eu

Advocacy The EGSCT serves as a professional adviser to stakeholder communities and regulatory bodies in Europe to strengthen the inclusion of gene and cell therapy topics in discussions at all levels. ESGCT has nominated representatives on the European Medicines Agency Committee for Advanced Therapeutics since its inception in 2008. 6 www.esgct.eu

Engaging the public Gene and cell therapies are topical sciences, regularly appearing in the media and as such there is a great deal of interest from the public. We run a public engagement event to promote and discuss the safe and effective advancement of gene and cell therapies. This event has gained media attention and a large number of regular participants, including patients and their families. 7 www.esgct.eu

Awards 10 Travel Grants for the highest abstract score for PhD students and first post-docs The Young Investigator Award for young investigators from PhD through to nine years post-doc The Outstanding Achievement Award for an established researcher who has made a long term contribution to the field The Breakthrough Investigator Award for a researcher who has made a significant scientific breakthrough 8 www.esgct.eu

Awards: Eligibility criteria General eligibility criteria 1. Candidates must be members of the European Society for Gene and Cell Therapy 2. Candidates must be nominated by two (or more) ESGCT members 3. Candidates must have conducted original research in basic science, technology development and/or clinical translation in the field of gene and cell therapy 4. Awardees must be available to give a presentation of their work at the ESGCT Annual Congress Award-specific eligibility criteria: TRAVEL GRANTS Awarded to PhD students or first post docs. Selection is based on highest abstract score at the annual ESGCT Congress. YOUNG INVESTIGATOR AWARD All young investigators from PhD through to nine years post doc* are now eligible to apply for the Young Investigator Award. *Extension of this period may be allowed in case of eligible career breaks: maternity or paternity leave (one year per child born after the PhD award), leave taken for long-term illness, national service, leave taken for unavoidable statutory reasons (e.g. clinical qualification). The cumulative eligibility period should not surpass 12 years following award of first PhD. For medical doctors, eligibility is based on completion date of clinical speciality. For MD, PhD, eligibility is based on date of PhD award. THE OUTSTANDING ACHIEVEMENT AWARD Awarded to an established researcher who has made a long term contribution to the field. The winner of this award will also be eligible for the Breakthrough Investigator Award (an additional 500 and a trophy). Nomination and selection process Nominations must be submitted by two or more ESGCT members, in writing to the ESGCT board, no later than 24th August. Nomination letters should provide an overview of the candidate s contributions to the field of gene therapy. Nominations materials to include: Two or more nomination letters from ESGCT members (500 words or less) Curriculum Vitae and Bibliography of nominee PDF copies of the applicant s two best papers All nominations will be reviewed by the ESGCT Awards Selection Committee 9 www.esgct.eu

Membership information ESGCT membership offers: Information about grant opportunities in Europe that would help to facilitate networking between laboratories Instant access to a worldwide network of other members through our multisearch, online Members Directory Online access to renew your membership, register for conferences and update your personal details via the members only area of the website Reduced congress fees A reduced membership fee when multiple members from the same organisation join together (10 or more joining at the same time will receive a 10% discount. Please quote same purchase order reference in each application and contact accounts@esgct.eu for joint invoice to be generated) FREE online subscription to Human Gene Therapy, the first journal to publish information on gene therapy, with in-depth coverage of DNA, RNA, and cell therapies. New expanded subscription with HGT Methods (18 issues per year!) Fees: Students: 30 Euros Academics: 60 Euros Industry: 180 Euros Apply for membership online at: http://www.esgct.eu/members/register 10 www.esgct.eu

Feedback The scientific programme was excellent. The session on stem cell niche was simply outstanding. I enjoyed the wealth of the congress programme and the diversity of the considered topics. The congress reported new findings relating to cell and gene therapy in many areas. It was a great networking opportunity. I enjoyed the talks about the clinical trials that are ongoing in the field of gene and cell therapy. Also the possibility of networking and starting new collaborations. The catering and social evening were fantastic. The lectures from invited speakers were excellent. Excellent scientific programme. Excellent and friendly support from the WATS.ON and local organising teams, particularly in the preparation and running of parallel meetings. 11 www.esgct.eu

Contact Gaëlle Jamar, Events Manager Tel (landline): +44 1235 833876 Tel (mobile): +44 7766 475379 Email: office@esgct.eu www.esgct.eu ESGCT is managed by WATS.ON Ltd www.wats-on.co.uk Renée Watson, Director ESGCT Board Nathalie Cartier-Lacave (President) Robin Ali (Vice-President) Hildegard Büning (General Secretary) Christof von Kalle (Treasurer) Alessandro Aiuti Juan Bueren Sarah Ferber Hidde Haisma Zoltan Ivics Adrian Thrasher Denis Vallese (student member, social media advisor) Registered address ESGCT, c/o Prof. C. von Kalle DKFZ, Abteilung Translationale Onkologie, G100 Im Neuenheimer Feld 460 69120 Heidelberg, Germany ESGCT Office 1 Abbey Street, Eynsham, Oxfordshire, OX29 4TB, UK 12 www.esgct.eu Photographs: www.vivaciousmelphotography.com. Design: www.catherinecharnock.co.uk

IN COLLABORATION WITH XXIVTH ANNUAL CONGRESS Partnership opportunities for the joint ESGCT-ISSCR ABCD congress: CHANGING THE FACE OF MODERN MEDICINE: STEM CELLS & GENE THERAPY 18 21 OCTOBER 2016 Palazzo degli Congressi, Firenze The European Society of Gene & Cell Therapy warmly invites you to join us in Florence, Italy, for our annual meeting in 2016, in collaboration with the ISSCR and ABCD This is the perfect opportunity to: Leverage the ESGCT, ISSCR and ABCD to meet key decision-makers in a close, personal setting Associate your brand with leaders and emerging leaders at the forefront of translational science 13 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIVTH ANNUAL CONGRESS CHANGING THE FACE OF MODERN MEDICINE: STEM CELLS & GENE THERAPY 18 21 OCTOBER 2016 Palazzo degli Congressi, Firenze This congress will combine four days of important presentations and discussions covering topics which will range from biology to clinical application of cell and gene therapy in the following areas: Hematopoietic stem cells Skeletal and cardiac muscle stem cells Neural stem cells FORMAL Cancer immuno-gene therapy AND INFORMAL KEYNOTE New gene editing technologies and organoids NETWORKING SPEAKER: HANS CLEVERS SOCIAL EVENTS In vivo liver-directed gene therapy POSTER PRESENTATIONS CLOSING SPEAKER: GEORGE DALEY OUTSTANDING AWARD WINNER: AMIT NATHWANI CONFIRMED PLENARY SPEAKERS: John Dick, Len Zon, Luigi Naldini, Marina Cavazzana, Christine Mummery, Mauro Giacca, Michael Laflamme, Luis Garcia, Fred H. (Rusty) Gage, Masaio Takahashi, Malin Parmar, Paul Tésar, Gianpietro Dotti, Carl June, Stanley Riddell, Chiara Bonini, Feng Zhang, Angelo Lombardo, Melissa Little, Pierre Vanderhaeghen, Katherine High, Alberto Auricchio, Mark A. Kay 14 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIVTH ANNUAL CONGRESS CHANGING THE FACE OF MODERN MEDICINE: STEM CELLS & GENE THERAPY 18 21 OCTOBER 2016 MERCATO CENTRALE Palazzo degli Congressi, Firenze Molecular Mingle social evening at the Mercato Centrale Speaker Dinner at the Palazzo Vecchio PALAZZO VECCHIO 15 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIVTH ANNUAL CONGRESS CHANGING THE FACE OF MODERN MEDICINE: STEM CELLS & GENE THERAPY 18 21 OCTOBER 2016 Palazzo degli Congressi, Firenze 18 PARALLEL SESSIONS, INCLUDING: PARALLEL SESSION SPEAKERS WILL BE INVITED AND SELECTED FROM SUBMITTED ABSTRACTS 16 Hematopoietic stem cells and mesenchymal stem cells therapy Spheres, organoids and scaffolds Stem cell niches, regeneration and aging Cancer stem cells Mobile genetic elements, reprogramming and gene therapy DNA repair and aging Stem cell based disease modelling Cell and gene therapy of ocular diseases, neurodegenerative diseases, cardiovascular system In vivo gene therapy and modulation of immune response DNA and RNA based vectors Genome editing, gene targeting and gene correction Targeted cancer gene therapy and oncolytics Manufacturing of cell and gene therapy products WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIV TH ANNUAL CONGRESS Title Partner: EURO 50,000 (Only 1) Recognition as Title Partner on the meeting website and official meeting programmebook Your logo on congress lanyards, badges, delegate bag, marketing material Sole sponsorship of one session One double exhibition stand in premium location (9x4m, 1 table, 2 chairs, wifi and electricity) One double spread advertisement in meeting programme Company description in the programme Complimentary meeting registration for four company employees. Additional registrations available at 50% discount off the prevailing non-member/corporate rate Named supporter of one social networking activity. Recognition includes the opportunity to make opening welcome remarks at the event (limited to 2 minutes); one sign at the event with your full-color logo designating your support Select one: Welcome and Poster Party 1 on Tuesday 18 October Poster Party 2 and speaker on Wednesday 19 October Molecular Mingle (Social Evening) on Thursday 20 October 17 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIV TH ANNUAL CONGRESS Diamond Level Support: Euros 30,000 (Only 3) Recognition as Diamond Supporter on the meeting website and official meeting programme book Sole sponsorship of one session One exhibition stand in premium location (3x2m, 1 table, 2 chairs, wifi and electricity) One full page advertisement in meeting programme Company description in the programme Complimentary meeting registration for three company employees. Additional registrations available at 50% discount off the prevailing non-member/corporate rate. Opportunity to make one company collateral item available to attendees with registration materials Named supporter of one social networking activity. Recognition includes the opportunity to make opening welcome remarks at the event (limited to 2 minutes); one sign at the event with your full-color logo designating your support Select one: Welcome and Poster Party 1 on Tuesday 18 October Poster Party 2 and speaker on Wednesday 19 October Molecular Mingle (Social Evening) on Thursday 20 October 18 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIV TH ANNUAL CONGRESS Platinum Level Support: Euros 15,000 Recognition as Platinum Supporter on the meeting website and official meeting programme book Sole sponsorship of 1 session One exhibition stand (3x2m, 1 table, 2 chairs, wifi and electricity) One full page advertisement in meeting programme Company description in the programme Complimentary meeting registration for two company employees. Additional registrations available at 50% discount off the prevailing non-member/corporate rate Opportunity to make one company collateral item available to attendees with registration materials Named supporter of one social networking activity. Recognition includes one sign at the event with your full-color logo designating your support Select one: Welcome and Poster Party 1 on Tuesday 18 October Poster Party 2 and speaker on Wednesday 19 October Molecular Mingle (Social Evening) on Thursday 20 October 19 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIV TH ANNUAL CONGRESS Gold Level Support: Euros 10,000 Recognition as Gold Supporter on the meeting website and official meeting programme book Joint sponsorship of 1 session One exhibition stand (3x2m, 1 table, 2 chairs, wifi and electricity) One half-page advertisement in meeting programme Company description in the programme Complimentary meeting registration for two company employees. Additional registrations available at 30% discount off the prevailing non-member/corporate rate 20 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIV TH ANNUAL CONGRESS Silver Level Support: Euros 5,000 Recognition as Silver Supporter on the meeting website and official meeting programme book Company description in the programme One tabletop exhibition stand. (3x2m, 1 table, 2 chairs, wifi and electricity) Complimentary meeting registration for two company employee. Additional registrations available at 15% discount off the prevailing non-member/corporate rate Bronze Level Support: Euros 3,000 Recognition as Bronze Supporter on the meeting website and official meeting programme book Company description in the programme Complimentary meeting registration for one company employee. Additional registrations available at 10% discount off the prevailing nonmember/corporate rate Exhibitor Only: Euros 3,000 One Exhibition stand (3x2m, 1 table, 2 chairs, wifi and electricity) Logo and company description in the programme Complimentary meeting registration for 2 company employees. Additional registrations available at 10% discount off the prevailing non-member/corporate rate 21 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG

IN COLLABORATION WITH XXIV TH ANNUAL CONGRESS Optional extras 1 Logo-link and 100 words on ESGCT website all year round 1,000 2 Branded email signature on all congress announcements for 1 month of your choice (month allocated on first come first served basis) Price on application 3 Full page advert in Congress Book. A5 book distributed to all congress delegates approx. 800 Price on application 4 Email circulars to ESGCT membership (three per year for one year). Email to be approved by ESGCT Board Price on application 5 Inclusion on the ESGCT website s useful information pages: 250 words, logo and link on GMP or Regulations pages Price on application 6 Insert in delegate bags. Packs distributed to all congress delegates approx. 800 Price on application 7 Provide materials for congress (paper blocks, USB keys, name tags, pens etc.) Price on application 22 WWW.ISSCR.ORG WWW.ESGCT.EU WWW.ABCD-IT.ORG