Sephadex(tm) G-25 Chromatography Column

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Sephadex(tm) G-25 Chromatography Column Page 1 of 6 Sephadex(tm) G-25 Chromatography Column MSDS Number: Z7219 --- Effective Date: 03/17/98 1. Product Identification Synonyms: None CAS No.: Not available. Molecular Weight: Not Available. Chemical Formula: Not available. Product Codes: 7219 2. Composition/Information on Ingredients Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------- --------- Sephadex(tm) G-25 N/A 90-100% Yes 3. Hazards Identification Emergency Overview -------------------------- As part of good industrial and personal hygiene and safety procedure, avoid all unnecessary exposure to the chemical substance and ensure prompt removal from skin, eyes and clothing. J.T. Baker SAF-T-DATA (tm) Ratings (Provided here for your convenience) -----------------------------------------------------------------------------------------------------------

Sephadex(tm) G-25 Chromatography Column Page 2 of 6 Health Rating: 1 - Slight Flammability Rating: 0 - None Reactivity Rating: 0 - None Contact Rating: 1 - Slight Lab Protective Equip: GOGGLES; LAB COAT Storage Color Code: Orange (General Storage) ----------------------------------------------------------------------------------------------------------- Potential Health Effects ---------------------------------- Inhalation: No adverse health effects via inhalation. Ingestion: Not expected to be a health hazard via ingestion. Skin Contact: Not expected to be a health hazard from skin exposure. Eye Contact: Not expected to be a health hazard. Chronic Exposure: No adverse health effects expected. Aggravation of Pre-existing Conditions: 4. First Aid Measures Inhalation: Not expected to require first aid measures. Remove to fresh air. Get medical attention for any breathing difficulty. Ingestion: Not expected to require first aid measures. If large amounts were swallowed, give water to drink and get medical advice. Skin Contact: Not expected to require first aid measures. Wash exposed area with soap and water. Get medical advice if irritation develops. Eye Contact: Not expected to require first aid measures. Wash thoroughly with running water. Get medical advice if irritation develops. 5. Fire Fighting Measures Fire: Not considered to be a fire hazard.

Sephadex(tm) G-25 Chromatography Column Page 3 of 6 Explosion: Not considered to be an explosion hazard. Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Special Information: Use protective clothing and breathing equipment appropriate for the surrounding fire. 6. Accidental Release Measures Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal. 7. Handling and Storage Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product. 8. Exposure Controls/Personal Protection Airborne Exposure Limits: None established. Ventilation System: Not expected to require any special ventilation. Personal Respirators (NIOSH Approved): Not expected to require personal respirator usage. Skin Protection: Wear protective gloves and clean body-covering clothing. Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area. 9. Physical and Chemical Properties Appearance: Prepacked metallic or plastic column. Odor: Odorless. Solubility: Negligible (< 0.1%)

Sephadex(tm) G-25 Chromatography Column Page 4 of 6 Specific Gravity: ph: % Volatiles by volume @ 21C (70F): 0 Boiling Point: Melting Point: Vapor Density (Air=1): Vapor Pressure (mm Hg): Evaporation Rate (BuAc=1): 10. Stability and Reactivity Stability: Stable under ordinary conditions of use and storage. Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition. Hazardous Polymerization: Will not occur. Incompatibilities: Conditions to Avoid: 11. Toxicological Information No LD50/LC50 information found relating to normal routes of occupational exposure. --------\Cancer Lists\------------------------------------------------------ ---NTP Carcinogen--- Ingredient Known Anticipated IARC Category ------------------------------------ ----- ----------- ------------- Sephadex(tm) G-25 No No None 12. Ecological Information Environmental Fate:

Sephadex(tm) G-25 Chromatography Column Page 5 of 6 Environmental Toxicity: 13. Disposal Considerations Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements. 14. Transport Information Not regulated. 15. Regulatory Information --------\Chemical Inventory Status - Part 1\--------------------------------- Ingredient TSCA EC Japan Australia ----------------------------------------------- ---- --- ----- --------- Sephadex(tm) G-25 Exempt No No No --------\Chemical Inventory Status - Part 2\--------------------------------- --Canada-- Ingredient Korea DSL NDSL Phil. ----------------------------------------------- ----- --- ---- ----- Sephadex(tm) G-25 No No No No --------\Federal, State & International Regulations - Part 1\---------------- -SARA 302- ------SARA 313------ Ingredient RQ TPQ List Chemical Catg. ----------------------------------------- --- ----- ---- -------------- Sephadex(tm) G-25 No No No No --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- -TSCA- Ingredient CERCLA 261.33 8(d) ----------------------------------------- ------ ------ ------ Sephadex(tm) G-25 No No No Chemical Weapons Convention: No TSCA 12(b): No CDTA: No SARA 311/312: Acute: No Chronic: No Fire: No Pressure: No Reactivity: No (Pure / Solid) Australian Hazchem Code:

Sephadex(tm) G-25 Chromatography Column Page 6 of 6 Poison Schedule: WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR. 16. Other Information Label Hazard Warning: As part of good industrial and personal hygiene and safety procedure, avoid all unnecessary exposure to the chemical substance and ensure prompt removal from skin, eyes and clothing. Label Precautions: INTENDED FOR R & D USE ONLY. NOT ON THE TSCA INVENTORY. Label First Aid: Not applicable. Product Use: Chromatography. Research and Development Use Only. Note: Chemical substances that are manufactured or imported in small quantities solely for the use in Research & Development are not subject to the notification requirements of the Toxic Substances Control Act (TSCA), 15 USC 2604 (h) et seq. Reference - 40 CFR 720.36 These products are not on the TSCA Inventory. They are used only in Research and Development. Revision Information: MSDS Section(s) changed since last revision of document include: 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 16. Disclaimer: ****************************************************************************** Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION. ****************************************************************************** Prepared by: Strategic Services Division Phone Number: (314) 539-1600 (U.S.A.)