Industry Overview & Strategic Growth Framework

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A Pharmacy Innovation Company Industry Overview & Strategic Growth Framework Larry Merlo President & Chief Executive Officer

Agenda Rapidly-changing health care environment Uniquely positioned to drive results Our strategic growth framework 2

Highlights From The Past 15 Years In Health Care Health care system leaves many uninsured Fee-for-service physician models Rising chronic disease prevalence Brand-to-generic shift in pharmaceuticals Start of transition to a digital society 3

How We See The Health Care Environment Changing In The Next 5-10 Years 1 In the past Health care system leaves many uninsured In the future Newly-insured lives & new funding sources 2 Fee-for-service physician models Providers as critical players in new ways 3 Rising chronic disease prevalence Focus on low-cost, high-quality solutions 4 Brand-to-generic shift in pharmaceuticals Specialty pharmacy growth accelerates 5 Start of transition to a digital society New tech-driven delivery methods 4

1 Health Care Reform Will Result In Newly-covered Lives And New Funding Sources Health Care Coverage (millions of lives) 2010 2016E % Change Uninsured 47 30-36% Medicaid 46 57 +24% Medicare 44 52 +18% Individual 14 35 +150% Employer-sponsored insurance 153 146-5% Total covered lives 257 290 +13% 38% increase in government and individual segments Source: CVS Caremark analysis. 5

2 Physicians Increasingly Reimbursed Under Pay-for-performance Models Physician Expectations On Practice Changes (percent of physicians) Already Doing This Now Very Likely Within 3 Years Pursue aggressive cost-saving efforts 57 Increase quality tracking/reporting Increase evidencebased medicine 55 54 Almost half of physicians believe they will be reimbursed under pay-forperformance within 3 years Reimbursed under pay for performance 42 Source: McKinsey 2011 Physician Survey. 6

3 Cost Of Care For Chronic Disease Dominates Health Care 118 Chronic Disease Prevalence Growing Rapidly (millions of lives) 125 133 141 149 157 164 171 1995 2000 2005 2010 2015E 2020E 2025E 2030E Chronic disease accounts for 84% of all health care spending Source: Robert Wood Johnson Foundation. 7

4 Brand-to-generic Conversions Continue, But At A Slower Rate Than Recent Years Retail Generic Dispensing Rate (% prescriptions) 47.8 55.0 63.2 69.9 75.6 81.8 85.0 86.0 2003 2005 2007 2009 2011 2013E 2015E 2017E Source: CVS Caremark analysis. 8

4 Specialty Pharmacy Dominates Pharma Growth Total U.S. Drug Sales ($ billions) 401 CAGR, 2010-16 (percent) 275 124 13% Specialty 60 Non-specialty 215 277 4% 2010 2016E Number Of Specialty Products In Top Ten 3 8 Sources: CVS Caremark analysis; IMS Health; Buck Consultants; NHE; Credit Suisse; Kaiser Commission on Medicaid and the Uninsured; Kaiser Family Foundation; September 2011; 7 reasons why specialty drug dispensing will boom. Specialty Pharmacy Times, June 2012. 9

5 Advances In Technology Have Potential To Significantly Reshape Consumer Behavior And Health Care Delivery Multi-channel Touchpoints Enhanced mobile platforms/apps Social media Innovative Delivery Models Telemedicine Telepharmacy HIT Tools E-prescribing Electronic health records Clinical decision support tools Advanced Analytics Tools to support predictive modeling Next generation personalization 10

Agenda Rapidly-changing health care environment Uniquely positioned to drive results Our strategic growth framework 11

Capitalizing On The Power Of Our Combined Entity To Drive Long-term Growth Access Cost Quality 12

CVS Caremark s Distinctive Business Model Is Uniquely Positioned To Drive Results 1 Unmatched purchasing scale 2 Deep clinical expertise 3 Strong client and consumer relationships 4 Channel-agnostic approach 13

1 Unmatched Purchasing Scale: A Major Competitive Advantage 990 Prescriptions Filled Annually (millions) 785 450 295 280 100 15 Walgreens Express Scripts Rite Aid Wal-Mart OptumRx Catamaran Notes: 1. Adjusted pharmacy claims normalize volumes for the difference in average days supply for mail and retail claims. 2. Estimates for Express Scripts and OptumRx are on a pro-forma basis, assuming shift of UNH volumes from Express Scripts to OptumRx upon termination of the legacy Medco contract. Sources: Company data & filings; Drugstore News; CVS Caremark analysis. 14

2 Deep Clinical Expertise: Combining Best-in-class Clinical Experience Across The Enterprise Diverse Insights Cross-enterprise clinical expertise Deep understanding of consumer behavior Medical research collaborations Best-in-class Interventions Industry-leading adherence metrics Best use of most influential advisor Actionable information at point of care Next Generation Pharmacy Care Programs Behavioral economics and predictive analytics Advanced targeting to effectively engage members 15

3 Strong Client And Consumer Relationships Meeting The Needs Of A Diverse PBM Client Base 5% (% of 63 million PBM lives) Leveraging Consumer Insights And Highest Influence Advisor ~5 million retail customers daily 8% 44% 70 million ExtraCare cardholders 15% Retail pharmacist 2-3x more influential 28% Employer Aetna PDP Health Plan FEP Unmatched ability to coordinate plan designs and influence consumer behavior Note: PBM client mix based on 2012 membership. 16

4 Channel-agnostic Approach: Enhances Patient Access And Drives Enterprise Share 28% 30% 31% 18% 16% 23% 19% 18% 19% 19% 20% 21% 2007 2008 2009 2010 2011 2012E CVS/pharmacy Share Of Caremark Retail Network Claims CVS/pharmacy Share Of U.S. Retail Market CVS/pharmacy share of Caremark book of business growing faster than overall retail market share Notes: 1. 2011and 2012E for CVS/pharmacy share of Caremark retail network claims excludes Aetna and CCRx claims. 2. Includes all 90-day claims filled at retail under the Maintenance Choice program. 17

4 Channel-agnostic Approach: Integrated Model Enables Share Gains Regardless Of Channel Shifts Industry Mail Order Share Of U.S. Prescriptions 17.7% 19.0% 18.6% 18.5% 18.2% 2007 2008 2009 2010 2011 Mail order growth may slow further in the coming years Sources: IMS Health; CVS Caremark analysis. 18

Unmatched Ability To Capture Outsized Share Of PBM Client Spend Across The Enterprise % Of PBM Clients CVS Caremark Share Of Client Rx Volume 18% > 80% 22% 61% - 80% Capturing >80% of volume for 18% of clients 40% 31% - 60% 20% 0% - 30% 100% 38% (avg.) 19

Unmatched Ability To Capture Outsized Share Of PBM Client Spend Across The Enterprise % Of PBM Clients CVS Caremark Share Of Client Rx Volume 18% > 80% 22% 61% - 80% 40% 31% - 60% Capturing 60% - 80% of volume for another 22% of clients 20% 0% - 30% 100% 38% (avg.) 20

Unmatched Ability To Capture Outsized Share Of PBM Client Spend Across The Enterprise % Of PBM Clients CVS Caremark Share Of Client Rx Volume 18% > 80% 22% 61% - 80% Opportunity 40% 31% - 60% 20% 0% - 30% 100% 38% (avg.) Significant opportunity remains to capture greater share of client spend 21

Uniquely Positioned To Drive Better Health Outcomes And Lower Costs Client A Client B Maintenance Choice Pharmacy Advisor Exclusive Specialty Generic dispensing rate 77.0% 68.4% Medication adherence (MPR) 83.5% 80.3% Gross cost per eligible member $2,305 $2,697 CVS Caremark enterprise share of Rx volume 86% 55% Note: Client s A & B shown above reflect retiree populations. 22

Uniquely Positioned To Drive Share Gains Purchasing Scale Clinical Insights Client / Customer Relationships Channel Agnostic Standalone PBM Standalone Retail Pharmacy Integrated Health Plan/PBM 23

Agenda Rapidly-changing health care environment Uniquely positioned to drive results Our strategic growth framework 24

Strategic Growth Framework Will Help Define Our Key Opportunities And Priorities In The Coming Years Unique integrated model Create greater health care value Reinventing pharmacy for better health Serve customers in new ways Enhanced shareholder value A changing external environment Optimize enterprise assets 25

Strategic Growth Framework Will Help Define Our Key Opportunities And Priorities In The Coming Years Create greater health care value Unique integrated model Increase convenience and quality of care Reinventing pharmacy for better health Serve customers in new ways Identify and target opportunities to better serve fastest-growing customer segments Enhanced shareholder value A changing external environment Optimize enterprise assets Deliver innovative solutions that leverage unmatched breadth of capabilities 26

Sweet Spot Initiatives Began Building On Our Unique Integrated Model Winning In Medicare Unique integrated model Reinventing pharmacy for better health Create greater health care value Serve customers in new ways Integrated Specialty Maintenance Choice 2.0 Pharmacy Advisor 3.0 Digital Strategy A changing external environment Optimize enterprise assets Health System Alliances Caremark Member Care At MinuteClinic 27

Future Strategic Initiatives Motivated By Key Health Care Market Insights Unique integrated model Create greater health care value Unlock Adherence Transform Primary Care Reinventing pharmacy for better health Serve customers in new ways Expand Role In Specialty Differentiate For Providers A changing external environment Optimize enterprise assets Partner With Health Plans Integrated Digital Offering 28

Uniquely Positioned For Growth Rapidly-changing health care environment creates opportunities for growth Uniquely positioned to address those opportunities through pharmacy innovation Strategic growth framework provides lens for strategic investments and initiatives Capitalizing on unique integrated model to drive results and enhance value 29