SAFETY DATA SHEET 10X Wash Buffer

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1. IDENTIFICATION Product Name Recommended use of the chemical and restrictions on use Identified Uses For Research and Development Use Only Product Numbers 190201, 190275 Company Identification Covaris, Inc. 14 Gill Street, Unit H Woburn, MA 01801 Customer Information Number (781) 932-3959 Emergency Telephone Number (800) 424-9300 (for emergencies only) Chemtrec Number (800) 424-9300 Issue Date October 28, 2013 Supersedes Date Safety Data Sheet prepared in accordance with OSHA s Hazard Communication Standard (29 CFR 1910.1200)and the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) 2. HAZARD IDENTIFICATION Hazard Classification This product is classified as not hazardous in accordance with the Globally Harmonized System of Classification and Labelling (GHS). Label Elements Hazard Symbols Signal Word: Hazard Statements Precautionary Statements Prevention Response Storage Disposal Other Hazards Revision Date: October 28, 2013 Page 1 of 6

2. HAZARD IDENTIFICATION Specific Concentration Limits The values listed below represent the percentages of ingredients of unknown toxicity. Acute oral toxicity 1-10% Acute dermal toxicity 1-10% Acute inhalation toxicity 10-20% Acute aquatic toxicity 10-20% 3. COMPOSITION/INFORMATION ON INGREDIENTS This product is a mixture. Component CAS Number Concentration Non hazardous mixture N.A. 100% 4. FIRST- AID MEASURES Description of necessary first-aid measures Eyes Flush the eye with plenty of water. Obtain medical attention if symptoms persist. Skin Wash affected area with plenty of water. Seek medical attention if symptoms persist. Ingestion Rinse mouth with plenty of water. Inhalation Not an expected route of entry. Most important symptoms/effects, acute and delayed Aside from the information found under description of necessary first aid measures (above) and Indication of immediate medical attention and special treatment needed, no additional symptoms and effects are anticipated. Indication of immediate medical attention and special treatment needed Notes to Physicians Treat symptomatically. 5. FIRE - FIGHTING MEASURES Suitable (and unsuitable) Extinguishing Media Use foam, dry chemical or carbon dioxide. Use water spray for surroundings and containers. Specific hazards arising from the chemical known. Special Protective Actions for Fire-Fighters Wear full protective clothing and self-contained breathing apparatus. Revision Date: October 28, 2013 Page 2 of 6

6. ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Wear appropriate protective clothing. Environmental Precautions Prevent the material from entering drains or watercourses. Methods and materials for containment and cleaning up Contain and absorb using earth, sand or other insert material. Transfer into suitable containers for recovery or disposal. 7. HANDLING AND STORAGE Precautions for safe handling Wear appropriate protective equipment when handling. Do not eat or drink while handling this material. Conditions for safe storage Store at room temperature away from heat and direct sunlight. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Exposure limits are listed below, if they exist. Non Hazardous Ingredients established. Appropriate engineering controls No specific measures necessary. Individual protection measures Respiratory Protection Respiratory protection not normally required. Skin Protection Gloves Eye/Face Protection Safety glasses Body Protection Normal work wear. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Physical State Liquid Color Colorless Odor Odor Threshold ph 8 Specific Gravity Boiling Range/Point ( C/F) Melting Point ( C/F) Flash Point (PMCC) ( C/F) Not flammable Revision Date: October 28, 2013 Page 3 of 6

9. PHYSICAL AND CHEMICAL PROPERTIES Vapor Pressure Evaporation Rate (BuAc=1) Solubility in Water Vapor Density (Air = 1) VOC (g/l) Partition coefficient (noctanol/water) Viscosity Auto-ignition Temperature Decomposition Temperature Upper explosive limit Lower explosive limit Flammability (solid, gas) Complete Not applicable 10. STABILITY AND REACTIVITY Reactivity No known reactivity. Chemical Stability Stable under normal conditions. Possibility of hazardous reactions Hazardous polymerization will not occur. Conditions to Avoid Heat high temperatures Incompatible Materials Strong oxidizing agents Hazardous Decomposition Products Oxides of carbon nitrogen oxides hydrogen chloride gas sodium oxides 11. TOXICOLOGICAL INFORMATION Acute Toxicity to indicate product is acutely toxic. Specific Target Organ Toxicity (STOT) single exposure to indicate product or components will cause target organ effects after a single exposure. Specific Target Organ Toxicity (STOT) repeat exposure to indicate product or components will cause target organ effects after repeated exposure. Serious Eye damage/irritation to indicate product or components may cause eye irritation. Skin Corrosion/Irritation to indicate product or components may cause skin irritation. Revision Date: October 28, 2013 Page 4 of 6

11. TOXICOLOGICAL INFORMATION Respiratory or Skin Sensitization to indicate product or components may cause skin or respiratory sensitization. Carcinogenicity Not considered carcinogenic by NTP, IARC, and OSHA. Germ Cell Mutagenicity to indicate product or any components present at greater than 0.1% are mutagenic or genotoxic. Reproductive Toxicity to indicate either product or components present at greater than 0.1% may cause reproductive toxicity or birth defects. Aspiration Hazard to indicate product is an aspiration hazard. 12. ECOLOGICAL INFORMATION Ecotoxicity Mobility in soil Persistence/Degradability Bioaccumulative Potential Other adverse effects 13. DISPOSAL CONSIDERATIONS Disposal Methods Dispose of in accordance with all applicable local and national regulations. 14. TRANSPORT INFORMATION DOT CFR 172.101 Data UN Proper Shipping Name UN Class UN Number UN Packaging Group Classification for AIR Transportation (IATA) Environmental Hazards Not Regulated Not Regulated... Consult current IATA Regulations prior to shipping by air. Not a marine pollutant Revision Date: October 28, 2013 Page 5 of 6

15. REGULATORY INFORMATION United States TSCA Inventory All components of this product have been verified for the inventory listing requirements of the US Toxic Substance Control Act (TSCA) Chemical Substance Inventory. Canada DSL Inventory All components of this product have been verified for inclusion on the Domestic Substance List (DSL). WHMIS Classification This product was classified in accordance with the hazard criteria of the Canadian Controlled Products Regulations and the MSDS contains all the information required by these regulations. SARA Title III Sect. 311/312 Categorization 16. OTHER INFORMATION NFPA Ratings NFPA Code for Flammability - 0 NFPA Code for Health - 0 NFPA Code for Reactivity - 0 NFPA Code for Special Hazards HMIS Ratings HMIS Code for Flammability - 0 HMIS Code for Health - 0 HMIS Code for Physical Hazard - 0 HMIS Code for Personal Protection - See Section 8 *Chronic Legend ACGIH: American Conference of Governmental Industrial Hygienists CAS: Chemical Abstracts Service IARC: International Agency for Research on Cancer N/A: Denotes no applicable information found or available NTP: National Toxicology Program OSHA: Occupational Safety and Health Administration PEL: Permissible Exposure Limit SDS: Safety Data Sheet STEL: Short Term Exposure Limit TLV: Threshold Limit Value Information Source and References This SDS is prepared by Hazard Communication Specialists based on information provided by internal company references. Prepared By: EnviroNet LLC. The information and recommendations presented in this SDS are based on sources believed to be accurate. Covaris assumes no liability for the accuracy or completeness of this information. It is the user's responsibility to determine the suitability of the material for their particular purposes. In particular, we make NO WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESS OR IMPLIED, with respect to such information, and we assume no liability resulting from its use. Users should ensure that any use or disposal of the material is in accordance with applicable Federal, State, and local laws and regulations. Revision Date: October 28, 2013 Page 6 of 6