Elements for discussion on Nanotechnologies, Advanced Materials, Biotechnology and Advanced Manufacturing and Processing 2018-2020 Version 07/03/17 This document contains elements aimed at facilitating an early discussion in the Committee. It does not represent a draft work-programme, and may change in both content and structure, even substantially. Page 1 of 65
Contents 1 - FOUNDATIONS FOR TOMORROW S INDUSTRY... 5 1.1 OPEN INNOVATION HUBS... 6 1.2. MATERIALS CHARACTERISATION AND COMPUTATIONAL MODELLING... 6 1.3 GOVERNANCE, SCIENCE-BASED RISK ASSESSMENT AND REGULATORY ASPECTS... 6 NMBP-12-2018: Risk Governance nanotechnology (RIA)... 7 NMBP-13-2018: Nanoinformatics: from materials models to predictive (eco)toxicology (RIA)... 8 NMBP-14-2019: Safe by design, from science to regulation: metrics and main sectors (RIA)... 10 NMBP-15-2020: Safe by design, from science to regulation: behaviour of multicomponent nanomaterials (RIA)... 12 NMBP-16-2020: Regulatory science for medical technology products (RIA) INCO with US, Japan, but not exclusively... 12 2 - TRANSFORMING EUROPEAN INDUSTRY... 13 2.1. FACTORIES OF THE FUTURE (FoF)... 14 DT-FoF-01-2018: Skills needed for new Manufacturing jobs (CSA)... 15 DT-FoF-02-2018: True Human-Robot Collaboration (RIA)... 16 DT-FoF-03-2018: Innovative manufacturing of opto-electrical parts (RIA)... 17 DT-FoF-04-2018: Pilot lines for metal Additive Manufacturing (IA 50%)... 19 DT-FoF-05-2019: Open Innovation for collaborative production (IA)... 20 DT-FoF-06-2019: Refurbishment and re-manufacturing of large industrial equipment (IA)... 21 DT-FoF-07-2019: Reliable and accurate assembly of micro parts (RIA)... 22 DT-FoF-08-2019: Pilot lines for modular factories (IA 50%)... 23 DT-FoF-09-2020: Holistic energy-efficient factory management (IA)... 24 DT-FoF-10-2020: Pilot lines for large-part manufacturing (IA 50%)... 24 DT-FoF-11-2020: Quality control in smart manufacturing (IA)... 24 FoF-12-2020: Handling systems for flexible materials (RIA)... 24 DT-NMBP-17-2019: Materials, manufacturing processes and devices for organic and large area electronics (IA)... 25 DT-NMBP-18-2019: Advanced materials for additive manufacturing (IA)... 26 Page 2 of 65
DT-NMBP-22-2018: A digital 'plug and produce' online equipment platform for manufacturing (IA)... 27 2.2 BIOTECHNOLOGY... 29 BIOTEC-01-2018: Standardisation in Synthetic Biology (CSA)... 30 BIOTEC-02-2018: Boosting the efficiency of photosynthesis (RIA)... 31 BIOTEC-03-2018: Synthetic biology to expand diversity of nature's chemical production (RIA)... 32 CE-BIOTEC-04-2019: New biotechnologies for environmental remediation (RIA) 33 CE-BIOTEC-05-2019: Microorganism communities for plastics bio-degradation (RIA)... 33 BIOTEC-06-2020: Reprogrammed microorganisms for biological sensors (IA)... 35 BIOTEC-07-2020: Multi-omics for the optimisation of genotype-phenotype associations (RIA)... 35 2.3. MEDICAL TECHNOLOGY INNOVATIONS... 36 NMBP-19-2018: Active implants (RIA)... 36 NMBP-20-2019: Custom-made biological scaffolds for specific tissue regeneration and repair (RIA)... 37 NMBP-21-2018: Osteo-articular tissues regeneration (RIA)... 38 3 - INDUSTRIAL SUSTAINABAILITY... 41 3.1. SUSTAINABLE PROCESS INDUSTRY (SPIRE)... 41 CE-SPIRE-01-2018: Industrial symbiosis (IA)... 42 CE-SPIRE-02-2018: Processing of material feedstock using non-conventional energy sources (RIA)... 43 CE-SPIRE-03-2018: Energy and resource efficiency in highly energy intensive industries (IA)... 45 CE-SPIRE-04-2019: Efficient integrated downstream processes (IA)... 46 CE-SPIRE-05-2019: Adaptation to variable feedstock through retrofitting (IA)... 47 DT-SPIRE-06-2019: Digital technologies for improved performance in cognitive production plants (RIA)... 48 CE-SPIRE-07-2020: Recovery of industrial water, thermal energy and substances contained therein (IA)... 50 CE-SPIRE-08-2020: Improved Industrial Processing using novel high-temperature resistant materials (RIA)... 50 CE-SPIRE-09-2020: Making the most of mineral waste, by-products and recycled material as feed for high volume production (IA)... 50 Page 3 of 65
CE-SPIRE-10-2020: Improved production of recyclable materials containing plastics (IA)... 50 3.2. CATALYSING THE CIRCULAR ECONOMY... 51 CE-NMBP-23-2018: Catalytic transformation of hydrocarbons (RIA)... 51 CE-NMBP-24-2019: Photocatalytic synthesis (RIA)... 53 CE-NMBP-25-2020: Materials and structures with intelligent recycling properties by design (RIA)... 54 3.3. CLEAN ENERGY THROUGH INNOVATIVE MATERIALS... 54 LC-NMBP-26-2018: Strengthening EU materials technologies for non-automotive battery storage (IA)... 55 LC-NMBP-27-2020: Advanced materials for innovative multilayers for durable photovoltaics (IA)... 57 LC-NMBP-28-2019: Materials for non-battery based energy storage (RIA)... 57 LC-NMBP-29-2020: Materials for future highly performant electrified vehicle batteries (RIA)... 58 LC-NMBP-30-2020: Materials for off shore energy (IA)... 58 3.4. ENERGY-EFFICIENT BUILDINGS... 59 LC-EeB-01-2019: Integration of energy smart materials in non-residential buildings (IA)... 59 LC-EeB-02-2018: Building information modelling adapted to efficient renovation (RIA)... 60 LC-EeB-03-2019: New developments in plus energy houses (IA)... 61 LC-EeB-04-2020: Industrialisation of building envelope for the renovation market (IA)... 62 LC-EeB-05-2019/20: Integrated storage systems for residential buildings (IA)... 63 LC-EeB-06-2018/20: ICT for proactive residential buildings and construction, design to end of life (IA)... 64 Page 4 of 65
1 - FOUNDATIONS FOR TOMORROW S INDUSTRY The ambition under this section is to lay the foundations for tomorrow s industry and create jobs through an ecosystem for upscaling advanced materials and nanotechnologies. This should enable a vast array of applications and allow innovators to bring their ideas to the market. Open innovation will be served with hubs, ensuring the widest possible access and user involvement. Openness to the world will be served through a flagship in nanosafety. The open innovation hubs and computational modelling in this section will make an indispensable contribution to the focus area on Digitising and Transforming European Industry and Services, by combining digital and physical advances for innovative new products and services. Page 5 of 65
1.1 OPEN INNOVATION HUBS [to be completed] 1.2. MATERIALS CHARACTERISATION AND COMPUTATIONAL MODELLING [to be completed] 1.3 GOVERNANCE, SCIENCE-BASED RISK ASSESSMENT AND REGULATORY ASPECTS Managing the risks of every emerging technology is of key importance for its societal acceptance and consequent possible success. The overall challenge is to establish a suitable form of nanotechnology innovation governance including risk governance, and to ensure that new technologies are beyond the state of the art and accepted by stakeholders (research, industry, regulators). This requires working on three different layers: (i) a scientific research layer for sound foundations, (ii) a regulatory research layer to validate and translate the scientific findings into appropriate regulatory frameworks and implementation, and (iii) a market layer dealing with the daily management of risks and safety. These three distinct layers must be integrated and this will be addressed by actions aiming at establishing innovation governance. This will include the challenge of ensuring consistency in all EU Member States in terms of risk management. Nanomaterials are core to many nanotechnology applications and products on the market today but also, more importantly, in future technologies which are expected to bring wealth and contribute to solving societal challenges linked to health, energy or the environment, to name a few. Addressing possible risks for human health and the environment is an inherent part of all nanotechnologies programmes worldwide and needs to be incorporated in any innovation governance programs. At the scientific research layer Risk (Hazard and Exposure) Assessment is well advanced whereas Safe-by-Design makes its first steps and must be pursued, notably through nano-informatics approaches, which also offer good chances for innovation. Similarly, the present rapid evolution and convergence of different sciences and novel technologies in the healthcare sector require the constant addition and adaptation of involved stakeholders, including medical regulators. Global-level regulatory science must be advanced, promoting the development and adoption of common reference and technical standards world-wide and at the same time maintain and enhance European access to worldwide markets. Europe is a global leader in medical sciences and this should translate into a leading voice in global debates In terms of resources, the regulatory layer should be jointly supported by H2020, MS governments and industry. At market level H2020 should support only the networking and coordination. Projects in all layers can foresee modalities for integrating additional public or private funding or foresee specific calls for projects funded by these additional sources. Costs Page 6 of 65
for the organisation of the calls and coordination of the work can be foreseen in projects' budgets. To maximise projects overall synergy and joint impact projects should take account of the strategy and roadmaps in place and contribute to the objectives of relevant platforms (such as the EU Nano Safety Cluster www.nanosafetycluster.eu) and foresee the necessary resources to this effect. Projects in this area must apply the Open Access and the Open Data Access policies. Nano-safety issues are global and, therefore, international collaboration is strongly encouraged. In particular, all projects in this area are expected to collaborate with similar projects under the established scheme of Communities of Research with the USA NNI programme (www.us-eu.org) and/or to include direct participation of relevant USA entities. In addition, participation from countries actively involved in the work of OECD -WPMN, the NanoSafety Cluster and the NANoREG project (e.g. South Korea, Brazil, Canada, Australia, China, Japan, South Africa) is strongly encouraged. Additionally, projects should support the activity of EU regulatory bodies and agencies, and of international organisations like ISO, CEN and OECD. NMBP-12-2018: Risk Governance nanotechnology (RIA) Specific challenge: Significant progress has been achieved in relation to research regarding the safety of nanomaterials and considerable efforts have been put in place to transfer this knowledge into regulation. Still, more needs to be done to cover not only the research but also the innovation phase. To fill this gap transdisciplinary innovation governance, including risk governance, is required. It should be based on a clear understanding of risk and of societal risk perception by all stakeholders. It should propose and apply clear criteria for risk evaluation and acceptance and for transfer of acceptable risk. It should develop reinforced decision making tools incorporating those aspects and facilitate risk communication to relevant stakeholders, including industry, regulators, insurance companies and the general public. The implementation of innovation governance should take societal concerns and ethical considerations into account and increase the societal trust in nanotechnology, thereby strengthening the sustainability of the sector. Innovation governance will need to encompass the entire material life-cycle, from scientific research and product development through use until end of life. It shall address the different stages of product innovation. For this to be effective, development of skills through education and training are required. Scope: Update data and information management in regard to the safety of nanomaterials that takes into account the existing EU and MS information platforms and previous EUfunded project results (e.g. NanoSafety Cluster, data management recommendations, Nano-observatory, DaNa, nano-smile) for risk assessment, for both hazard and exposure and for both human health and the environment, and risk mitigation including regulatory aspects of safe-by-design.. Page 7 of 65
. Responsible communication with stakeholders and the civil society based on good quality information. The aim should be to develop reliable decision making, risk monitoring and feed-back procedures based on improved understanding of risk perception and behaviour at stakeholder levels. is of crucial importance. Plans for future scientific and regulatory research paying attention to social, ethical and environmental aspects should be established aiming at completeness, consistency, maximum synergy of actions and international cooperation. These should be based on past experiences, include appropriate pre-market assessment of potential impact in different stages of product innovation, post use monitoring, and organised consultation of stakeholders and public dialogue. Mechanisms to monitor progress in several industrial sectors and revise plans. To assess the potential for governance of nanomaterials, the various instruments used to capture the processes and products of such materials should be considered Activities are expected to focus on Technology Readiness Levels 5 to 6. The Commission considers that proposals requesting a contribution from the EU between EUR X and Y million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts. Expected impact: Establish and launch a transparent, self-sustained and science-based risk governance body. Govern possible nanotechnologies risks through governance frameworks in order to implement their social, environmental and economic benefits. Sustainable solutions at a level that will allow both consistent integration of scientific results and regulatory application of scientifically sound concepts. Ensure consistency of science based risk management approaches in all EU Member States. Ensure synergy with similar actions internationally Type of Action: Research and Innovation Action NMBP-13-2018: Nanoinformatics: from materials models to predictive (eco)toxicology (RIA) Specific challenge: Despite the significant amounts of data on physico-chemical and (eco)toxicological properties of nanomaterials generated over the last decades, detailed knowledge on how (eco)toxicity is linked to specific physico-chemical characteristics is only beginning to emerge. The challenge is to develop and implement modern methods (more cost Page 8 of 65
effective and less reliant on animal testing) for toxicity investigations in each stage of product innovation, through making best use of joining existing and emerging data with the help of progress in informatics. Knowledge from different disciplines such as material science, biology, chemistry, toxicology, medicine or computational science has to be integrated to deliver models linking material design to (eco)toxicological properties. There is a requirement to develop new approaches to best harness the drastically increased detail of both material characterisation and biological endpoints, and the amount of recorded data developed in the last decade, and to combine that with the paradigm shift in (eco)toxicology towards stronger emphasis on the use of computational approaches to deliver predictive models applicable for different stakeholders. Therefore, nanoinformatics, i.e. the storage and analysis of data relevant to nanotechnology including the development and use of specific computational tools or models, will be crucial for reliable safe-by-design development of products ensuring sustainable nanotechnology innovation. Scope: Making the best possible use of currently existing data scattered in diverse project databases to further develop nano-ontologies will require harmonization of existing databases, such that data along with metadata from different data sources can be integrated. This should underpin development of models that support the prediction of specific functionalities, (eco)toxicological behaviour and hazard, as well as being crucial to establish safe-by-design principles. Such model utilisation demands and may also support the analysis of data quality in available and future datasets, and facilitate the implementation of intelligent testing strategies with feed-forward mechanisms to continuously improve experimental design and data completeness. This will allow for prioritization and hazard ranking of NMs, enable grouping and support regulatory decision-making. Development of a sustainable multi-scale modelling framework, based on the integration/ linking of different types of models is essential in order to advance towards predictively link physico-chemical NM property models to NM functionality and nano(eco)toxicology to explore and establish their interrelationships as part of a decision framework for risk governance of nanomaterials. To ensure uptake and valid use of these tools and models appropriate validation protocols, operational limitations, and approaches to communicate the associated uncertainties have to be established. Finally, user-friendly interfaces to enhance accessibility and usability of the models, and clear explanations of their applicability domains must be provided for different stakeholders (industry, regulators, and researchers). Activities are expected to focus on Technology Readiness Levels 4 to 6. The Commission considers that proposals requesting a contribution from the EU between EUR X and Y million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts. Page 9 of 65
Type of Action: Research and Innovation Action Expected impact: Reliable nanomaterials safety data systems that should provide; long-term sustainable standards and solutions for data and metadata storage, inter-operability between different data platforms, and ability to integrate new and existing data in data analysis and curation. Provide the required best practise science, models and strategies needed to allow material characteristics to be linked to adverse outcomes and identification of key descriptors associated with health and environmental impacts of NMs providing a meaningful basis for grouping, read-across purposes. Translating scientifically validated techniques and ready to use models into systems and recommendations ready for use within or direct incorporation into regulation and management through an accessible framework, designed to predict human and environmental toxicological hazards, which allows integration of platforms across the different modelling scales, end-points and application areas. Increased confidence in nanosafety predictive models through agreed standards, harmonised standard operating procedures; considering OECD validation principles; Relevant indicators and metrics, with baseline values, must be clearly stated in the proposal. NMBP-14-2019: Safe by design, from science to regulation: metrics and main sectors (RIA) Specific challenge: Risk management involves quantifying hazard (toxicity) and exposure and taking the necessary steps to reduce those to acceptable levels, ideally at an early stage of the nanomaterial development process (Safe-by-Design). Various industrial sectors, and in particular structural or functional materials, coatings and cosmetics are currently searching for ways to mitigate possible risks from nanomaterials and nano-containing products. Different methods to measure chemical and biological (re)activity as well as early markers for adverse (eco)toxicological) effects of substances have been developed and others may still come up. The challenge now is to distil these into simple, robust, cost-effective methods for monitoring of physical-chemical properties and biological effect assessment of nanomaterials including in product-relevant matrices. Special attention should be paid to Safe by Design and covering the full product lifecycle including ageing and products of degradation of nanomaterials used in those sectors. Scope: Degradation of nanoenabled product lines will necessitate dealing with mixture toxicity (e.g. nanomaterials interactions with pharmaceuticals, nanomaterials interactions with endocrine disruptors in the environment, etc.), and should be considered. Ageing of nanomaterials, which may modify their surface properties and also lead to the formation of new materials and chemicals forms and consequently of degradation mixtures, focusing on Page 10 of 65
products that are relevant in terms of production volumes and potential release along their life cycle. These new safe by design methods should enable identification of drivers of exposure or hazard to be reduced through design without affecting the material performance and should guide development of safer products by safe innovation at different stage gates. The starting point is the numerous good design, usage and formulation practices to minimize exposure to chemicals that could be used to mitigate human and environmental exposure to nanomaterials. Given the absence of regulatory consensus on the effectiveness of controls related to release and exposure. The challenge is to collate the various sources of information on effectiveness of control measures and mitigation strategies (for chemical substances and/or nanomaterials specific scenarios), to fill data gaps by gathering new data, reach regulatory consensus on the effectiveness of such measures, and develop computational approaches to model them. Ultimately, acceptance for the implementation of control measures and mitigation strategies in the various sectors is the route to allow managed or restricted use of products where the hazard element cannot be reduced. For this topic the parallel calls scheme is envisaged with the USA-NNI. Resulting projects should establish close cooperation mechanisms. Legal, policy making and RRI aspects should be integrated in the proposal Activities are expected to focus on Technology Readiness Levels 4 to 6. The Commission considers that proposals requesting a contribution from the EU between EUR X and Y million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts. Type of Action: Research and Innovation Action Expected impact: Safe by design approaches that at an early stage of the nanomaterial development process will mitigate possible risks from nanomaterials and nano-containing products and at the same time ensure maximum technical and economic performance. Establish and validate control measures and exposure mitigation in specific scenarios leading to quality workplaces and at the same time ensure maximum technical and economic performance. Control and mitigate exposure after release of nanomaterials from products during activities, through ageing of nanomaterials/products, or by formation of new (degradation) material and chemical forms Develop and validate, preferably low cost, techniques for delivering an integrated exposure driven risk assessment and the associated design of the required post use monitoring. Relevant indicators and metrics, with baseline values, must be clearly stated in the proposal. Page 11 of 65
NMBP-15-2020: Safe by design, from science to regulation: behaviour of multicomponent nanomaterials (RIA) NMBP-16-2020: Regulatory science for medical technology products (RIA) INCO with US, Japan, but not exclusively Page 12 of 65
2 - TRANSFORMING EUROPEAN INDUSTRY The ambition under this section is to transform European industry through the integration of digitisation and other enabling technologies, and achieve global industrial leadership. Open innovation will be served through the inclusion of more companies that will use these technologies to produce breakthrough innovations in products and processes, and through extensive societal engagement. Openness to the world will be served through two flagships, on global health care, and on biotechnology for the environment. The pillar covers: the manufacturing process itself, ranging from manufacturing excellence and flexibility to increased reliability, accuracy and durability, from improving energy efficiency and reuse of materials or re-manufacturing to skills development and novel ways for humanmachine interaction; the development of emerging and potentially disruptive biotechnologies; and the development of medical technologies for diagnosis and treatment. It will complement the first pillar 'Foundations for Tomorrow's Industry', and will likewise make an indispensable contribution to the focus area on Digitising and Transforming European Industry and Services, by combining digital and physical advances for innovative new products and services. Page 13 of 65
2.1. FACTORIES OF THE FUTURE (FoF) Better jobs in modern factories: The 'fourth industrial revolution' is radically altering job profiles and employment patterns. As a consequence, the workforce that was trained and acquired its skills many years ago must adapt. This is evident due to the recent creation of new type of professionals with a skills set fundamentally different to that which professionals had to acquire many years ago. Competition at global level will not allow continuous planning for the necessary adaptations of industries and workers environments. Therefore, the European Union must act in order to drive the creation of better jobs in modern factories. Accordingly, this narrative concerns the following topics: skills needed for new Manufacturing jobs (FoF-01-2018); and True Human-Robot Collaboration (FoF-02-2018) Manufacturing excellence: Industrial leadership benefits from developments in various fields such as production of micro assemblies and of very large parts, transformation towards smart manufacturing and fabrication of opto-electrical parts. Assemblies at the micro-scale bring about new functionalities and energy savings but considerable improvements are still needed in terms of accuracy, efficiency and reliability. Progress in the automation of large parts production and repair are real but still remain limited because most robots are ill-adapted to the size and weight of the elements to be handled. Smart manufacturing allows for rapid data treatment, which enables reliable, customised and fast production, but reliability, integration and data management strategies remain serious issues hampering the deployment of smart production lines. Finally, opto-electrical parts are essential to many modern objects but require further improvement in terms of durability, size and reliability. The challenge is to increase substantially the durability of various manufacturing technologies to enhance their adoption. Accordingly, this narrative concerns the following topics: innovative manufacturing of opto-electrical parts (FoF-03-2018); reliable and accurate assembly of micro parts (FoF-07-2019); pilot lines for large-part manufacturing (FoF-10-2020); and quality control in smart manufacturing (FoF-11-2020). Flexible and customised manufacturing: to deliver a high degree of customisation and flexibility in manufacturing, while maintaining production robustness. The customisation is driven by customer need for small lot sizes, and new innovative products. A producer must balance the customer requests against technical limitations in the production line. The variations in the lots require technical development of advanced processes targeting complex designs, versatile machines, and intelligent handling of work pieces. Additive manufacturing (AM) technology is a promising approach for fully customisable products, but aspects of its integration into a production line still needs to be addressed, in particular for metal AM. Similarly, a transition into advanced modular concepts may help reducing the production cost when reconfiguring the production line. In addition, the handling systems need to be adaptable to the ever-increasing variety of shapes, materials and sizes, including soft and flexible materials. Accordingly, this narrative concerns the following topics: pilot lines for metal Additive Manufacturing (FoF-04-2018); pilot lines for modular factories (FoF-08-2019); and handling systems for flexible materials (FoF-12-2020). Page 14 of 65
Towards open innovation: European business has been innovating successfully for many centuries, but the pace has intensified globally. North American, as well as Asian, economies are now setting a faster pace. This is a challenge for European business, with regard to the rising R&D costs that become necessary to stay competitive globally, and the new approaches that are needed to achieve market-creating innovation. Accordingly, this narrative concerns the following topic: open innovation for collaborative production (FoF-05-2019). Eco-factories: The continuously increasing demand for more products cannot be maintained unless manufacturing becomes more environmentally sustainable. As a major user of energy and one of the primary sources of hazardous emissions, manufacturing industry has an important role to play in achieving Europe's climate and energy objectives. Development of innovative technologies is necessary to improve the industrial energy efficiency of the factory as a whole and to lower its carbon footprint. Furthermore, the depletion of raw materials is pushing up the environmental impact and economic cost of the final product. New approaches to facilitate re-use of materials and re-manufacturing are critical for a more sustainable and competitive industry. Accordingly, this narrative concerns the following topics: refurbishment and re-manufacturing of large industrial equipment (FoF-06-2019); and holistic energyefficient factory management (FoF-09-2020). DT-FoF-01-2018: Skills needed for new Manufacturing jobs (CSA) Specific challenge: Modern industries need a trained and motivated workforce. The different companies' job profiles need to experience a transition to adapt to the increasingly sophisticated machines and new technologies. Breakthrough education and training paradigms are needed allowing the European industrial workforce to develop new skills and competences in a quick and efficient way. Advanced Manufacturing, one of the six Key Enabling Technologies (KETs), is a highly innovative sector in Europe. In line with the New Skills Agenda for Europe we need to strengthen human capital, employability and competitiveness for this KET. The Blueprint for Sectoral Cooperation on skills is one of the ten actions in this Agenda. This topic will complement the implementation of the Blueprint, by focusing in several areas from the Factories of the Future priorities. Scope: Identify shortages and mismatches in technical and non-technical skills, knowledge and competences for the current and new technologies, including digital capabilities. Map the most relevant existing national inventories to create EU wide industry transformation maps. Lifelong learning activities and granting of qualification for personnel in industrial plants. Real cases scenarios providing efficient methodologies that can be applied in a variety of sectors. Page 15 of 65
Innovative and hands-on approaches, addressing Social Sciences and Humanities (SSH) elements, in re-education of the workforce through training activities and knowledge management with direct involvement of senior employees. On-site, modular and e-learning education must be combined effectively to ensure workforce motivation in their professional development. Exchange of information between industry, trade unions, educational centres, national employment agencies at European scale. The proposals are also encouraged to seek for synergies with National initiatives funded under the European Social Fund and projects from the Skills Alliances. 1 proposal maximum; indicative requested EC funding 2 M Expected impact: Real and measurable steps towards the reduction of skill gaps and skill shortages that hinder the industry s innovation performance. At least 15 new job profiles per sector addressed, leading to longer work- life of the employees in their posts. Close engagement of relevant research, industrial, educational and unions stakeholders in Member States with concrete plans on exchange of information with technical universities and vocational schools. Type of Action: Coordination and Support Action DT-FoF-02-2018: True Human-Robot Collaboration (RIA) Specific challenge: Human-Robot collaboration (HRC) on the factory floor has a high potential economic impact for European industry. Past research to implement HRC in an industrial setting has largely focused on safety of humans, allowing workers and robots to share working space without fences. Most of the developments in HRC started from existing industrial robotic arms, augmenting it with technologies to make it safe for humans to interact with the robot. This has already led to production environments where safe interaction between humans and robots is possible, but true collaboration between humans and robots to improve the quality of the job performed and to increase flexible production, has not yet been demonstrated for manufacturing purposes. In order to move from a structured factory floor where robots work behind closed fences to an open environment with robots and humans closely collaborating, interdisciplinary research in the fields of robotics, cognitive sciences and psychology is required. More attention has to be paid to develop novel inherently-safe robotic concepts where collaboration with humans is taken up already in the design phase. In order for true HRC to be taken up by industry, beyond safety, aspects of ergonomics, adaptability, liability issues, acceptability and feedback from users need to be considered in a holistic way. Page 16 of 65
Scope: The proposal needs to focus on extending the current state of the art of individual user and individual robot collaboration to planning and implementing work environments where robots and workers function as members of the same team throughout the factory. To address this challenge the proposal needs to cover all of the following areas: Integration of novel human-centred designed robot technology for high payloads (e.g. soft robots) in production environments, excluding existing industrial robot arms. Implementation of novel artificial intelligence technologies capable of massive information processing and reacting in real-time to enable new levels of autonomy, navigation, cognitive perception and manipulation for robots to collaborate with humans in the process. Development of methods for robotic hazard assessment and risk management to clarify trade-offs between productivity and safety for mixed human-robot environments. Social Sciences and Humanities (SSH) elements regarding human-related barriers for the uptake of robot technology in industrial environments such as ergonomics, user experience, comfort, trust, feeling of safety and liability in modern production facilities taking into account the age and gender aspects. Proposals should include an outline of the initial exploitation and business scenarios, which will be developed further in the proposed project. TRL 4-6; Budget: EUR 8 and 10 million Expected impact: Demonstrating a business case to bring back production to Europe. 15% increase in OECD Job Quality Index through work environment improvement. 20% reduction in production reconfiguration time and cost. These objectives are to be measured against the levels before technology implementation in the specific demonstrators. All relevant indicators and values must be clearly stated in the proposal. Type of Action: Research and Innovation Action DT-FoF-03-2018: Innovative manufacturing of opto-electrical parts (RIA) Specific challenge: Optoelectronics and opto-electrical components involve in the interactions of photons and electrons. They are used in parts such as lasers, photodiodes, optical amplifiers, modulators, solar cells and light-emitting diodes. Previous research led to rapid developments and new applications in optoelectronics and photonics. However, new processes need to be introduced in their production systems. When Page 17 of 65
going into the scale-up phase, many processes need to be adjusted to fit the production of complex, often free-form components. The adjustments include both component specific changes as well as standard process steps. Due to the need to produce large varieties of parts in small batches, process adjustments have to be both rapid and accurate. The testing and control equipment needs to follow a fast pace of technical advancement, and address a range of multi-functional sensors, such as electrical, optical, magnetic and thermal sensing. Scope: Proposals need to present a variety of new processes applicable to the production of opto-electrical components, for instance material handling, patterning, material deposition, assembly, and bonding. Furthermore, the quality needs to be ensured by reliable multifunctional sensors throughout the production line. The processes need to include a level of sustainability in allowing for the final products to be recycled and reintroduced into the value chain. The proposal will need to cover all of the following areas: New, flexible, and innovative process chains to handle complex designs which include opto-electrical functionalities Improved sensor equipment targeting both quality control in the different processing steps, as well as the final functionality of the component Methodologies for improving quality through high-precision automation using the sensor data, including in-process evaluation of material and component properties Re-use and requalification of key components and precious materials within the process chain from products at their end of life. The proposal is expected to include a variety of use-case demonstrations of typical optoelectrical components, in which the robustness of the processing, work piece handling, sensing and the automation approach can be demonstrated. TRL 4-6; Budget: EUR 8 and 10 million Expected impact: 15% yield improvement because of the introduction of new sensor equipment, related metrology and automatic control. 15% time reduction for reconfiguration of key process tools in a production line due to change of type of component. A tangible part (> 10%) of the production cost of the parts should originate from recycled products and materials. These objectives are to be measured against the levels before technology implementation in the specific demonstrators. All relevant indicators and values must be clearly stated in the proposal. Type of Action: Research and Innovation Action Page 18 of 65
DT-FoF-04-2018: Pilot lines for metal Additive Manufacturing (IA 50%) Specific challenge: Cost and unpredictable defects in final parts and products are preventing complete deployment and adoption of Additive Manufacturing in the industrial sector. The industrial demonstration in a pilot line will show the full potential of AM in real manufacturing conditions. Quality aspects to be significantly improved include robustness, stability, repeatability, speed and right-first-time manufacturing. Scope: Multi-scale and multi-physics simulations of the process and of the whole system from the early design phase, to avoid costly trial and error runs. The prediction and minimisation of distortion for post processing steps will also avoid propagation of defects to downstream stages. In-line non-destructive testing and in-situ analysis of product, including metrology aspects. Integration and inter-operability of AM processes into multi-stage production systems, with in-process monitoring, feedback and control. Certification, regulatory and standardisation activities related to the proposed solutions. Occupational Exposure in terms of Health, safety and Environment must be carefully observed together with the recycling of unused materials. The projects are expected to cover demonstration activities in industrial settings considering previous project results. Therefore, it is suggested the consortium be composed of less than 10 partners and focused around industrial partners of whom at least one is a final user of the production line. Proposals should include an outline of the initial exploitation and business plans, which will be developed further in the proposed project. TRL: 7; Budget: EUR 15 and 20 million Expected impact: Increased robustness of AM-based processes by 40% and production speeds by 25%. Reduction of time to market by 25% and right first time capability by 40%. Reduction of the uncertainties of selected material quality parameters by 50%, resulting in improved product quality by 40%. New certification schemes for Industrial "3D-Printed" parts and products in collaboration with relevant certification stakeholders. Page 19 of 65
New standardisation of specific categories not included in current ISO/ASTM/CEN CENELC TCs. These objectives are to be measured against the levels before technology implementation in the specific demonstrators. All relevant indicators and values must be clearly stated in the proposal. Type of Action: Innovation Action (50% funding for profit-making entities) DT-FoF-05-2019: Open Innovation for collaborative production (IA) Specific challenge: Do It Yourself (DIY), FabLabs and Makers approaches, based on empowering people with technologies, can enable a pioneering way to inspire engineering solutions throughout the whole value chain. These innovative methods can lead to new processes, machines and products with new functionalities and shorter time to market. Industrial businesses are not used to such innovative approach. As a consequence, more innovative ways for engaging consumers and taking up societal needs are rarely addressed. Such collaborative production liaising industrial companies, especially SMEs, with these new approaches can create Open Innovation networks that can unroll a wide range of entirely new business opportunities. Scope: The proposals should particularly address consumer-goods sectors and couple design and creativity with a customer-driven production. In particular, they should cover the following areas: Novel approaches to capitalize the knowledge and ideas of design and engineering coming from different actors, inside and outside the company and of variety of stakeholders, e.g. engineers, technicians, production workers, external designers, endusers, consumers, fablabs, makers, hackers, including Social Sciences and Humanities (SSH) elements regarding creativity. Design of new strategies based on creative methodologies for analysis, e.g. value proposition canvas, empathy maps, lean canvas, and in the frame of cooperative events, e.g. Hackathons, Workshops, Innovation events. Develop technologies and tools to collect and analyse factual and emotional data and requirements from the users and provide solutions to enable collaborative and emotional engineering in the production network, allowing all partners to understand users' requirements and to propose innovative solutions. Ensure compatibility in open source product data exchange and standard representations of products and processes that ensure the compatibility of modelling and simulation with the different process information systems. TRL: 4 to 6; Budget: EUR 3 and 5 million Impact: Page 20 of 65
Establish Open-Innovation networks for manufacturing that support customer-driven production all around Europe. Creation of specific business models for the engineering of customised solutions, especially focusing on SMES, rapid demand changes and shorter time to market Improvement of the co-design and co-development capabilities towards a reduction of development costs of new products and services. Increase of product variety and personalization for higher customer satisfaction and loyalty. Type of Action: Innovation Action DT-FoF-06-2019: Refurbishment and re-manufacturing of large industrial equipment (IA) Specific challenge: In line with the circular economy, lifetime extension can help to limit high replacement costs of major industrial infrastructures. This can be achieved through refurbishment, re-manufacturing, re-use, in-situ repair, improved maintenance and more conservative utilisation of large industrial equipment of the kind used in manufacturing and power plants. These actions can significantly extend the useful life of heavy machinery, and improve the return on investment from major capital items. This is particularly relevant for large scale electrical and/or mechanical machinery in manufacturing industry. Electronic equipment has already been covered in earlier calls. These life extension approaches would contribute to the circular economy and encourage sustainability by delaying the need to manufacture replacement equipment. Scope: This topic is for a demonstration project to establish the feasibility of lifetime extension of large industrial equipment of the kind used in manufacturing and power plants built in the last fifty years. Proposals should address one or more of the following areas: refurbishment and/or upgrading of large industrial equipment, re-manufacturing and re-use of equipment, inspection and in-situ repair of damage, maintenance and optimised utilisation of large industrial equipment. These measures can improve the return on investment from major capital items. The focus is on large scale electrical and/or mechanical machinery and plant rather than electronic equipment which has already been well covered in projects funded in earlier calls. Demonstration activities need to take place in real industrial settings and include validation of at least two industrial demonstrators in different target sectors, enabling the integration and scale-up of the parameters to other industrial environments. TRL: 5-7; Budget: EUR 15 and 25 million Page 21 of 65
Expected impact: Material and resource efficiency increased by at least 10% Waste flows and material losses reduced by at least 10% These objectives are to be measured against the levels before technology implementation in the specific demonstrators. All relevant indicators and values must be clearly stated in the proposal. Type of Action: Innovation Action DT-FoF-07-2019: Reliable and accurate assembly of micro parts (RIA) Specific challenge: Micro-manufacturing is an essential aspect as miniaturisation leads to new functionalities, weight reduction and energy and material saving. European industry currently benefits from a leadership position in this field but investments in research and development of new manufacturing techniques are necessary to maintain this strategic advantage. Previous works have developed innovative technologies to produce and assemble micro-scale objects i.e. objects with a total volume < 1 mm3 and with the smallest dimension between 10µm and 300µm). However, further efforts are needed to combine accuracy, speed, productivity, efficiency and reliability. New production lines must be able to detect, and adapt with minimum human involvement to, variations in the environment or the components. Moreover, larger scale technologies cannot be directly applied to micro part assembly as physical phenomena that can be ignored at larger scale may affect strongly micro parts. Therefore, there is a need to develop models able to take into account these effects in order to effectively control the micro parts assembly processes. Scope: The proposal should propose new assembly technologies, especially for products containing micro-parts and which are currently assembled mostly manually because of technical limitations. For this purpose, proposals should cover all of the following areas: Methods of design for micro-assembly and disassembly including procedures, standardization aspects, and indices to assess the performance of micro-assembly devices. High throughput (cycle of a few seconds) automatic systems for micro-handling and assembly, including robust, reliable strategies to precisely grasp and release parts. In-line monitoring and quality assessment for the parts as well as for the assemblies. Advanced control methods and/or human in the loop strategies, dynamic task planning. Proposals should include pilots where industrial end-users will validate the demonstrated processes. The proposed solutions should be respectful of the environment and the workers, economically viable and easily transferable to other sectors or product types. Page 22 of 65
Budget 8-10 million; TRL 4-6 Expected impact: Decrease of both production cost and production time by at least 15%. Measurable increase of automation levels, especially the self-adaptation to changes. Higher level. Reduction of at least 20% in the number of parts and assemblies that are rejected or destroyed during the production process. These objectives are to be measured against the levels before technology implementation in the specific demonstrators. All relevant indicators and values must be clearly stated in the proposal. Ideally, processes should be applicable to various sectors with only minor adaptations. Type of Action: Research and Innovation Action DT-FoF-08-2019: Pilot lines for modular factories (IA 50%) Specific challenge: Rapid changes in a production line require a significant flexibility of reconfiguration. Modular production equipment can create highly adaptable production lines to enable efficient production of small series tailored to customer demands. Previous research has shown that the modularity can be at two levels, either as complete machines with their own interface and material handling system or as interchangeable tool heads. In both cases, the advantage of modularity should be demonstrated by the ease of use and plug-and-produce features allowing for rapid modification. The functionality of the modules should enable the production of the widest variety of complex products. The modules need to allow rapid physical rearrangements, either through automated processes or manual intervention, and to have accessible, secure interfaces in order to be connected to a common data system for production control. The interfacing with the existing hardware and legacy software is an aspect that needs to be further addressed as well. Scope: The proposal is expected to start from an existing pilot line that is flexible enough to allow for the introduction of multiple modular process units. Proposals should cover all of the following areas: The development of a range of production modules covering several different disciplines such as mechanical cutting tools, thermal processes, laser treatments and additive manufacturing technologies. The integration of comprehensive production management systems, including realtime process control in a reconfigurable line, which includes considerations for data interoperability between modules and process line (including legacy hardware and software). Page 23 of 65