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Name Date Period Biology S2: Final Exam Review Final Exam Study Guide Unit 1: Molecular Genetics 1. Terms to Know: A. Amino acid: B. Codon: C. Anticodon: D. Cancer: E. Gene Regulation: F. Crossing Over: G. Mitosis: H. Fertilization: I. Meiosis: J. Hox Genes: 2. Use the following terms to fill in the Venn Diagram for DNA and RNA: Ribose Deoxyribose Sugar Phosphate Nucleotides Nucleic Acid Cytosine (C) Guanine (G) Adenine (A) Uracil (U) Single Strand Double Helix Thymine (T) 3. Label the parts of a nucleotide below: Circle the part of the nucleotide that determines the genetic code for an organism.

4. Figure 1 shows base pairing in DNA. A. What kind of bonds are found between nitrogen bases, like adenine and thymine? B. Circle the bonds between each base pair. C. These bonds can break during replication and protein synthesis, so the DNA unzips. Why is it important for these bonds to break? Figure 1 5. Review the steps of replication and proteins synthesis. Part A is a strand of DNA that has already separated from its complementary strand. Follow the appropriate base pairing rules. Use the codon chart for part D. A. ATG CCC GTA GCG TGA B. Write the complementary DNA to the strand above: C. Write the mrna strand that would match strand B: D. Write the amino acids coded by the mrna in part C: E. Can a codon make more than one amino acid? Y / N F. Can an amino acid make more than one codon? Y / N G. There are 20 possible, while there are 64 possible. H. In what process would strand B be made from strand A? 6. Identify the labeled structures in Figure 2. A. B. C. D. E. F. G. Figure 2

7. Identify the labeled structures in Figure 3. A: B: C: D: E: F: -Process X is -Process Y is -Replication would make strand from strand. Figure 3 8. Use Figure 4 to help answer the questions below. A. What is the haploid number for this organism? N= B. What is the diploid number for this organism? 2N= C. Which letter represents meiosis? D. Which letter represents fertilization? E. Color the egg yellow; color the sperm blue; color the cell resulting from fertilization green. Figure 4 9. Complete the chart to compare mitosis and meiosis. Produces genetically cells Does crossing over occur? When? Number of Divisions Number of Daughter Cells Produced Starts with (Haploid or Diploid) Creates (Haploid or Diploid) Mitosis Meiosis

10. Figure 5 shows a cell going through regular mitosis. Draw the correct nucleus (with chromosomes) in each daughter cell. Figure 5 Figure 6 shows a cell going through regular mitosis. The cell in Figure 6 has a mutation caused by exposure to radiation. Draw the resulting nucleus (with chromosomes) in each daughter cell. Figure 6 11. Fill in the blanks using: specialized expressed genes DNA Cells within our body are, meaning they have specific functions. For example, red blood cells carry oxygen throughout our bodies, and muscle cells enable us to move. However, all of the cells in our body contain all of our. Cells are able to specialize because different are (turned on). 12. Hox genes determine the order, or location in which body structures develop. From, head to toe, place the following traits in order for a human: toes, arms, ears, knees, navel Unit 2: Molecular Genetics Terms to Know: A. Genotype B. Phenotype C. Dominant D. Recessive E. Homozygous F. Heterozygous (Hybrid) G. Carrier H. Codominance I. Multiple Alleles J. Sex-Linked Genes K. Polygenic Inheritance L. Gamete

1. A. What is the probability of flipping heads on a coin? % B. What is the probability of flipping heads on a coin twice in a row? % 2. Use Figure 7 to answer the questions about the following scenario: A man heterozygous for ear lobes is married to a woman who is homozygous for ear lobes. Trait DOMINANT recessive Hair Type Curly (wavy) hair Hair Color Dark Light Straight Hair Ear Lobe Free Attached Tongue Movement Ability to taste PTC (phenylthiocarbamide) Ability to roll sides Tasting Inability to Roll Sides Non-Tasting Figure 7 A. What is the genotype for the man? (use F s) B. What is the genotype for the woman (use F s)? C. Complete a punnett square showing the cross between this man and woman. D. What are the chances of them having a child with free ear lobes? % E. What are the chances of them having a child with attached ear lobes? % F. Can they produce a child that is: homozygous dominant? heterozygous? homozygous recessive? 3. A. Give the genotypes of the parents in the dihybrid cross in Figure 8: x B. What are the possible gametes for each parent?,,, Figure 8

4. Review the cats in question 3. Suppose a brown, short tail cat (SSBB) is mated with a white, long tail cat (ssbb). A. What is the genotype of all the offspring from these parents? B. What is the phenotype of all the offspring from these parents? 5. Create a dihybrid cross for a male cat that is heterozygous for both traits, and a female cat that is homozygous recessive for both traits. A. Give the genotypes of the parents: x B. Do FOIL to determine the male s possible gametes:,,, (Parent 1) And the female s possible gametes:,,, (Parent 2) C. Set up the cross using the square below: D. Give the correct number of individuals predicted to have each phenotype: short, brown short, white long, brown long, white 6. Snap dragon flowers show (circle one) incomplete dominance / codominance and can be red (RR), white (WW), or pink (RW). Draw a Punnett Square to cross two pink flowers. A. What is the phenotype ratio? B. What percentage of the offspring flowers will be pink? % C. In this form of inheritance, the heterozygous phenotype is 7. Cattle coat color shows (circle one) incomplete dominance / codominance and can be red (RR), white (WW), or roan (RW). Create a cross that will produce 50% roan calves and 50% white calves. A. What is the parental cross? x B. What is the probability that the first AND second calf will BOTH be roan? % C. In this form of inheritance, the heterozygous phenotype is

8. Fill in the chart below with the genotypes for each blood type, which is controlled by multiple alleles. Blood Type (Phenotype) Genotype(s) A B AB O 9. Make a Punnett Square showing the cross between a man with I B i and a woman with ii. Label each genotype of the offspring with the blood type. A. What are the blood types of the parents? B. What is the probability that their child will have Type O blood? C. Is it possible for these two parents to have a child with Type AB blood? Why or why not? 10. The given Punnett square shows a cross to determine the inheritance of hemophilia. Hemophilia is a recessive disorder that is found on the X chromosome. Answer the following questions: A. What term do we use to describe the mother who is heterozygous? B. Does the father have hemophilia? YES / NO C. What is the probability that their son will have hemophilia? % D. Is it possible for their daughter to have hemophilia? YES / NO Unit 3: Common Ancestry & Diversity Terms to Know: A. Evolution B. Theory C. Hypothesis D. Cladogram 1. Urey and Miller performed an experiment using water, ammonia, methane, and hydrogen. They alternately heated and cooled these chemicals. They used jolts of electricity to imitate lightning. A. What was the purpose of their experiment? B. What can we conclude from their experiment?

2. Figure 9 shows an example of a cladogram. Use it to answer questions A-C. A. Which two organisms are most closely related? & B. Which two are most distantly related? & C. Which two listed traits do salamanders and pigeons have in common? & D. What trait(s) do mice and chimps have that pigeons do not? Figure 9 3. Looking at Figure 10 below, note how the gill slit folds have change from the fish to the reptile, bird, and human. The gill slits shown in the human embryo suggest that humans shared an early common ancestor with which group? (Circle the organism on the diagram). Figure 10 4. Evolution is a theory because there is a vast amount of evidence to support it, and new information is gathered all the time that continues to support it. Check any of the items below that are valid examples of evidence for the theory of evolution. Homologous structures Analogous structures Vestigial structures DNA evidence/amino acid sequences Geological evidence/fossil record Similarities in embryo development Based on this evidence, scientists believe that Earth is billion years old. 5. Based on the information in Figure 11 below, which organism is most closely related to humans? (circle the name) Figure 11

6. Tell whether each statement regarding amino acid sequences is true or false. A. The differences in amino acid sequences show differences in DNA, and provide evidence of common ancestry. B. The differences in amino acid sequences show genes flowing, as one species mates with another. C. Only amino acid sequences can be used to create the most updated cladograms. 7. When the Earth first formed, there was very little oxygen in the atmosphere. Now, there is about 21% oxygen in the atmosphere. A. Which biological process was primarily responsible for the abundance of oxygen in the Earth s atmosphere? B. Where did the oxygen come from? C. What type of organisms were the first ones to make oxygen? Unit 4: Mechanisms of Evolution Terms to Know: A. Natural Selection B. Survival of the Fittest C. Struggle for Existence D. Adaptation E. Adaptive Radiation F. Convergent Evolution G. Coevolution H. Genetic Equilibrium I. Disruptive Selection J. Stabilizing Selection K. Directional Selection L. Temporal Isolation M. Geographic Isolation N. Behavioral Isolation O. Speciation 1. Darwin s theory of natural selection involves the survival of individuals who are best adapted for their environment. These individuals: A. Have adaptations that: increase fitness / decrease fitness B. Have adaptations that: are acquired / are inherited C. Will: compete successfully / not compete successfully within their species. D. Will produce: fewer offspring / more offspring than others in the population. 2. Asian carp are an invasive species in many of our waterways. The Asian carp are able to prey on many other species of fish due to their large size and lack of a natural predator. Which part of Darwin s concept of natural selection might be used to describe this situation? Survival of the Fittest / Variation and Adaptation / Struggle for Existence 3. In a population of squirrels, 250 are born, yet only 125 survive to reproduce. Which part of Darwin s concept of natural selection might be used to describe this situation? Survival of the Fittest / Variation and Adaptation / Struggle for Existence

4. The finches on the Galapagos Islands each developed beaks that best-suited the type of food available on each island. Which part of Darwin s concept of natural selection might be used to describe this situation? Survival of the Fittest / Variation and Adaptation / Struggle for Existence 5. List possible adaptations for each of the organisms below: A. Polar bear: C. Wolf: B. Finch: D. Newt: 6. Darwin s finches may be seen in Figure 12. Figure 12 A. Which finch would be best at eating large seeds? B. Why is there a variation is beak size for insect-eating birds? C. Each group of finches developed differences in their beaks to reduce for food. 7. What are some factors in an environment that may cause a population size to change? 8. A species of butterfly can be white, tan, or speckled (white and tan). A. The speckled butterflies blend in best with their environment (tree bark), and are best adapted to avoid predators. This means they are more likely to survive and pass on their genes. What would you expect to happen to this butterfly population over time? B. Consider the original butterfly population. Pollution from a nearby factory changed the bark of the tree, so now the tan butterflies blend best with the environment. What would you expect to happen to this butterfly population over time? 9. How does Figure 13 show convergent evolution? Why does convergent evolution take place? Figure 13

10. Match each type of reproductive isolation with the correct example listed below: A. Behavioral Isolation B. Geographic Isolation C. Temporal Isolation American toads reproduce between February and March, while Fowler s toads reproduce during May and June. Female fireflies will only respond to the flash pattern of males from their species, but will ignore the flash pattern of males from other closely related species. American finches from California migrated to Hawaii and can no longer breed with individuals from the mainland. Why does the geographic isolation of two populations of a species tend to increase differences between their gene pools? 11. When traits are controlled by more than one gene, the effects of natural selection are more complex. The range of phenotypes often form a bell curve. A. Selection: individuals at one end of the curve have higher fitness than individuals in the middle or at the other end. B. Selection: individuals near the center of the curve have higher fitness than individuals at either end. C. Selection: individuals at the outer ends of the curve have higher fitness than individuals at the middle 12. Match each of the diagrams below to the correct type of selection from number 1. Graph 1: Graph 2: Graph 3: 13. Complete the 5 parts of the Hardy-Weinberg principle below. Populations that follow all 5 parts of this principle are said to be in. Populations that follow all 5 parts of this principle will evolve / stay the same.