Tsai, Wei-Bor ( 蔡偉博 ) Professor B.S. in Chemical Engineering National Taiwan University, 1989 M.S. in Biochemical Sciences National Taiwan University, 1991 Ph.D. in Bioengineering University of Washington, 1998 Research and Professional Interests Biomaterials Tissue engineering Drug delivery Projects ( stared from 2011 ) 1. 利用多巴胺聚合以包覆奈米藥物顆粒於釋放藥物醫療植體之應用 NT$ 2,025,000, 國科會,100-2221-E-002-114-MY2, 08/01/2011-07/31/2013 2. 紡織產業卓越創新研究中心業務推展計畫 NT$ 350,000, 紡織研究所,04/01/2011-12/31/201 3. 磷酸鹽陶瓷之骨誘導作用研究 NT$ 1,131,000, 國科會,100-2622-E-002-019-CC2, 06/01/2011-05/31/2012 Journal Papers 1. Hsuan-Liang Liu, Ching-Tao Yang, Jian-Hua Zhao, Chih-Hung Huang, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, Wei-Bor Tsai, Molecular dynamics simulations to investigate the effects of zinc ions on the structural stability of the c-cbl RING domain, Biotechnol Prog., 23(5):1231-1238, 2007. 2. Wei-Bor Tsai, Peng-Yuan Wang, Yung Chang and Min-Cheng Wang, Fibronectin and culture temperature modulate the efficacy of an avidin-biotin binding system for chondrocyte adhesion and growth on biodegradable polymers, Biotechnology and Bioengineering, 98(2): 498-507, 2007. 3. Jian-Hua Zhao, Hsuan-Liang Liu, Hsin-Yi Lin, Chih-Hung Huang, Hsu-Wei Fang, Shiao-Shing Chen, Yih Ho, Wei-Bor Tsai, Wen-Yih Chen, Chemical chaperone and inhibitor discovery: potential treatments for protein conformational diseases, Perspectives in Medicinal Chemistry, 1:39-48, 2007. 4. Hsuan-Liang Liu, Fu-Chiang Yang, Hsin-Yi Lin, Chi-Hung Huang, Hsu-Wei Fang, Wei-Bor Tsai, Yung-Chu Cheng, Artificial neural network to predict the growth of the indigenous Acidthiobacillus thiooxidans, Chemical Engineering Journal, 137(2):231-237, 2008. 5. Hsu-Wei Fang, Hsien-Chieh Wang, Teh-Hua Tsai, Wei-Bor Tsai, Shao-Yi Hou, Hsuan-Liang Liu, Wun-Hsin Lee, Yung-Chang Lu, Chun-Hsiung Huang, An accelerated wear testing with microfabricated surface to evaluate the lubrication ability of biomolecules on polyethylene, Journal of Applied Polymer Science, 108:2428-2437, 2008. 6. Jian-Hua Zhao, Ching-Tao Yang, Josephine W. Wu, Wei-Bor Tsai, Hsin-Yi Lin, - 207 -
Hsu-Wei Fang, Yih Ho, Hsuan-Liang Liu, RING domains functioning as E3 ligases reveal distinct structural features: a molecular dynamics simulation study, Journal of Biomolecular Structure & Dynamics, 26(1), 65-74, 2008. 7. Jian-Hua Zhao, Hsuan-Liang Liu, Yi-Fan Liu, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, Wei-Bor Tsai, Molecular Dynamics Simulations to Investigate the Aggregation Behaviors of the Aβ(17-42) Oligomers, Journal of Biomolecular Structure & Dynamics, 26(4):481-490, 2009. 8. Peng-Yuan Wang, Hsiang-Hong Chow, Hsu-Wei Fang, Wei-Bor Tsai, Modulation of gene expression of rabbit chondrocytes by dynamic compression in polyurethane scaffolds with collagen gel encapsulation, Journal of Biomaterials Applications, 23: 347-366, 2009. 9. Hsiu-Wen Chien, Tsung-Yao Chang, Wei-Bor Tsai, Spatial control of cellular adhesion using photo-crosslinked micropatterned polyelectrolyte multilayer films, Biomaterials, 30:2209 2218, 2009. 10. Wei-Bor Tsai Jia-Hua Lin, Modulation of morphology and functions of human hepatoblastoma cells by nano-grooved substrata, Acta Biomaterialia, 5(5): 1442-1454, 2009. 11. Wei-Bor Tsai, Yen-Chung Ting, Jung-Yen Yang, Juin-Yih Lai, Hsuan-Liang Liu, Fibronectin modulates the morphology of osteoblast-like cells (MG-63) on nano-grooved substrates, Journal of Materials Science: Materials in Medicine, 20:1367 1378, 2009. 12. Liang-Kai Chang, Jian-Hua Zhao, Hsuan-Liang Liu, Kung-Tien Liu, Jenn-Tzong Chen, Wei-Bor Tsai, Yih Ho, Molecular Dynamics Simulations to Investigate the Structural Stability and Aggregation Behavior of the GGVVIA Oligomers Derived from Amyloid beta Peptide, Journal of Biomolecular Structure & Dynamics, 26(6):731-740, 2009. 13. Jung-Yen Yang, Yen-Chung Ting, Juin-Yih Lai, Hsuan-Liang Liu, Hsu-Wei Fang, Wei-Bor Tsai, Quantitative analysis of osteoblast-like cells (MG63) morphology on nanogrooved substrata with various groove and ridge dimensions, Journal of Biomedical Materials Research: Part A, 90A: 629 640, 2009. 14. Wei-Bor Tsai, Ying-Hao Chen, Hsiu-Wen Chien, Collaborative cell-resistant properties of polyelectrolyte multilayer films and surface PEGylation on reducing cell adhesion to cytophilic surfaces, Journal of Biomaterials Science: Polymer Edition, 20:1611 1628, 2009. 15. Po-Sheng Fang, Jian-Hua Zhao, Hsuan-Liang Liu, Kung-Tien Liu, Jenn-Tzong Chen, Wei-Bor Tsai, Hsin-Yi Lin, Hsu-Wei Fang, and Yih Ho, Molecular Dynamics Simulations to Investigate the Relationship between the Structural Stability and Amyloidogenesis of the Wild-type and N-terminal Hexapeptide Deletion DN6 b2-microglobulin, Molecular Simulations, 35(9): 755-765, 2009. 16. Chi-An Dai, Chih-Chun Hsiao, An-Cheng Kao, Chien-Pan Liu, Wei-Bor Tsai, Wen-Shiang Chen, Wei-Ming Liu,Wen-Pin Shih and Chien-Ching Ma, A membrane actuator based on an ionic polymer network and carbon nanotubes: the synergy of ionic transport and mechanical properties, Smart Materials and Structures, 18(8): 085016, 2009. ( 工合著 ) - 208 -
17. Hsu-Wei Fang, Yu-Chih Su, Huei-Ting Huang, Wei-Bor Tsai, Hsuan-Liang Liu, Investigation of the friction induced conformational change of protein and wear of UHMWPE by a wear process with microfabricated surfaces, Materials Science and Engineering: C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 29(4): 1118-1123, 2009. 18. Peng-Yuan Wang, Hsiang-Hong Chow, Juin-Yih Lai, Hsuan-Liang Liu, Wei-Bor Tsai, Dynamic compression modulates chondrocyte proliferation and matrix biosynthesis in chitosan/gelatin scaffolds, Journal of Biomedical Materials Research: Part B, 91B(1): 143-152, 2009. 19. Chi-An Dai, An-Cheng Kao, Wei-Bor Tsai, Wen-Shiang Chen, Wen-Pin Shih, and Chien-Ching Ma, Polymer Actuator Based on PVA/PAMPS Ionic Membrane: Optimization of Ionic Transport Properties, Sensors and Actuators A-Physical. 155:152 162, 2009. ( 工合著 ) 20. Wei-Bor Tsai, Rita Pei-Yeh Chen, Kuang-Ling Wei, Yi-Ru Chen, Tai-Yan Liao, Hsuan-Liang Liu, Juin-Yih Lai, Polyelectrolyte multilayer films functionalized with peptides for promoting osteoblast functions, Acta Biomaterialia, 5:3467 3477, 2009. 21. Wei-Bor Tsai, Rita Pei-Yeh Chen, Kuang-Ling Wei, Su-Fang Tan, Juin-Yih Lai, Modulation of RGD-functionalized polyelectrolyte multilayer membranes for promoting osteoblast function, Journal of Biomaterials Science: Polymer Edition, 21:377-394, 2010. 22. Veronica Glattauer, Jacinta F. White, Wei-Bor Tsai, Chen-Chi Tsai, Tracy A. Tebb, Stephen J. Danon, Jerome A. Werkmeister and John A.M. Ramshaw, Preparation of resorbable collagen-based beads for direct use in tissue engineering and cell therapy applications, Journal of Biomedical Materials Research: Part A, 92A(4): 1301-1309, 2010. 23. Lin, Y. F., Zhao, J. H., Liu, H. L., Liu, K. T., Chen, J. T., Tsai, W. B., Ho, Y., Structural stability and aggregation behavior of the VEALYL peptide derived from human insulin: A molecular dynamics simulation study, Biopolymers, 94(3):269-78, 2010. 24. Hsiu-Wen Chien, Su-Ping Wu, Wei-Hsuan Kuo, Meng-Jiy Wang, Chiapyng Lee, Wei-Bor Tsai, Modulation of hemocompatibility of polysulfone by polyelectrolyte multilayer films, Colloids and Surfaces B: Biointerfaces, 77(2): 270-278, 2010. 25. Peng-Yuan Wang, Hung-Te Yu, Wei-Bor Tsai, Modulation of alignment and differentiation of skeletal myoblasts by submicron ridges/grooves surface structure, Biotechnology and Bioengineering, 106(2):285-94, 2010. 26. Shiao-Wen Tsai, Yu-Hui Cheng, Yung Chang, Hsuan-Liang Liu, Wei-Bor Tsai, Type I collagen structure modulates the behavior of osteoblast-like cells, Journal of the Taiwan Institute of Chemical Engineers, 41:247 251, 2010. 27. Liang-Kai Chang, Jian-Hua Zhao, Hsuan-Liang Liu, Josephine W. Wu, Chih-Kuang Chuang, Kung-Tien Liu, Jenn-Tzong Chen, Wei-Bor Tsai, and Yih Ho, The importance of steric zipper on the aggregation of the MVGGVV peptide derived from the amyloid b peptide, Journal of Biomolecular Structure & Dynamics, 28(1):35-50, 2010. 28. Ying-Ling Liu, Yen-Hsing Wu, Wei-Bor Tsai, Chih-Chi Tsai, Wen-Shiang Chen, Chuan-Shao Wu, Core-shell silica@chitosan nanoparticles and hollow chitosan nanospheres using silica, Carbohydarte Polymers, 2010, accepted. - 209 -
29. Fu-Yin Hsu, Ya-Yun Cheng, Shiao-Wen Tsai, Wei-Bor Tsai, Fabrication and evaluation of a new biodegradable cohesive plug based on reconstituted collagen/γ-polyglutamic acid, J. Biomed. Mater. Res. Part B, 95B(1):29-35, 2010. 30. Jian-Hua Zhao, Hsuan-Liang Liu, Chih-Kuang Chuang, Kung-Tien Liu, Wei-Bor Tsai, and Yih Ho, Molecular dynamics simulations to investigate the stability and aggregation behavior of the amyloid-forming peptide VQIVYK from Tau protein, Molecular Simulation, 36(13): 1013 1024, 2010. 31. Shin-Hua Lu, Josephine W. Wu, Hsuan-Liang Liu, Jian-Hua Zhao, Kung-Tien Liu, Chih-Kuang Chuang, Hsin-Yi Lin, Wei-Bor Tsai, Yih Ho, The discovery of potential acetylcholinesterase inhibitors: A combination of pharmacophore modeling, virtual screening, and molecular docking studies, Journal of Biomedical Science, 18:8, 2011. 32. Ying-Ling Liu, Yen-Hsing Wu, Wei-Bor Tsai, Chih-Chi Tsai, Wen-Shiang Chen, Chuan-Shao Wu, Core-shell silica@chitosan nanoparticles and hollow chitosan nanospheres using silica, Carbohydrate Polymers, 84(2): 770-774, 2011. 33. Zheng-Li Zhou, Jian-Hua Zhao, Hsuan-Liang Liu, Josephine W. Wu, Kung-Tien Liu, Chih-Kuang Chuang, Wei-Bor Tsai, Yih Ho, The Possible Structural Models for Polyglutamine Aggregation: A Molecular Dynamics Simulations Study, Journal of Biomolecular Structure & Dynamics, 28(5): 743-758, 2011. 34. Lauren R. Clements, Peng-Yuan Wang, Frances Harding, Wei-Bor Tsai, Helmut Thissen, Nicolas H. Voelcker, Mesenchymal stem cell attachment to peptide density gradients on porous silicon generated by electrografting, Physica Status Solidi A, 208(6): 1440-1445, 2011. 35. Wei-Bor Tsai, Yi-Ru Chen, Hsuan-Liang Liu, Juin-Yih Lai, Fabrication of UV-crosslinked chitosan scaffolds with conjugation of RGD peptides for bone tissue engineering, Carbohydrate Polymers, 85(1): 129-137 2011. 36. Wei-Bor Tsai, Chih-Yuan Chien, Helmut Thissen, Juin-Yih Lai, Dopamine-assisted immobilization of poly(ethylene imine) based polymers for control of cell-surface interactions, Acta Biomaterialia, 7(6): 2518-2525, 2011. 37. Peng-Yuan Wang, Jiashing Yu, Jia-Hua Lin, Wei-Bor Tsai, Modulation of alignment, elongation and contraction of cardiomyocytes through a combination of nanotopography and rigidity of substrates, Acta Biomaterialia, 7(9):3285-3293, 2011. ( 合著 ) 38. Hsiu-Wen Chien, Shu-Fang Tan, Kuang-Ling Wei, Wei-Bor Tsai, Modulation of the functions of osteoblast-like cells on poly(allylamine hydrochloride) and poly(acrylic acid) multilayer films, Colloids and Surfaces B: Biointerfaces, 88(1): 297-303, 2011. 39. Wei-Bor Tsai, Wen-Tung Chen, Hsiu-Wen Chien, Wei-Hsuan Kuo, Meng-Jiy Wang, Poly(dopamine) coating to scaffolds for articular cartilage tissue engineering, Acta Biomaterialia, 7(12):4187-4194, 2011. 40. Wei-Hsuan Kuo, Meng-Jiy Wang, Hsiu-Wen Chien, Ta-Chin Wei, Chiapyng Lee, Wei-Bor Tsai, Surface Modification With Poly(sulfobetaine methacrylate-co-acrylic acid) to Improve Hemocompatibility of Biomaterials, Biomacromolecules, 12(12): 4348 4356, 2011. 41. Peng-Yuan Wang, Wei-Bor Tsai, Nicolas H. Voelcker, Screening of Rat Mesenchymal Stem Cell Behaviour on Polydimethylsiloxane Stiffness Gradients, Acta Biomaterialia, doi:10.1016/j.actbio.2011.09.030, in press, 2011. - 210 -
42. Lauren R. Clements, Peng-Yuan Wang, Wei-Bor Tsai, Helmut Thissen and Nicolas H. Voelcker, Electrochemistry-enabled fabrication of orthogonal nanotopography and surface chemistry gradients for high-throughput screening, Lab on a Chip, accepted, 2011. 43. Peng-Yuan Wang, Helmut Thissen, Wei-Bor Tsai, The roles of RGD and grooved topography in the adhesion, morphology and differentiation of C2C12 Skeletal Myoblasts, Biotechnology and Bioengineering, accepted, 2011. Conference Papers 1. H-W. Chien, T-Y. Chang, J-H. Lin, W-B. Tsai, Controlled cell spatial adhesion on micropatterned layer-by-layer polyelectrolyte multilayer films which are fabricated via photolithography at the 8th Asia Pacific Biochemical Engineering Conference, in Taipei, Taiwan, Nov 4-7, 2007 2. Y.-D. Lai, C.-A. Dai, W.-B. Tsai, W.-S. Chen, W.-P. Shi and C.-C. Ma, Fabrication of Artificial Sphincter Made of Nafion, at the 4th Conference on Aseanian Membrane Society, in Taipei, Taiwan, August 16-18, 2007. 3. Y.-H. Chen and W.-B. Tsai, The Peglyated Layer-by-Layer Polyelectrolyte Multilayer Membranes Inhibit L929 Cell Adhesion, at the 4th Conference on Aseanian Membrane Society, in Taipei, Taiwan, August 16-18, 2007. 4. P-Y. Wang, H-W. Fang, W-B. Tsai, The effect of cyclic mechanical compreession on articular cartilage tissue engineering at the 32th annual meeting of Society for Biomaterials, in Chicago, Illinois, USA, April 18-21, 2007 5. W-B. Tsai, Y-C. Ting, J-Y. Yang, The Effects of Fibronectin on Cell Adhesion to the Substrata with Nanogrooves/ridges structure at the 32th annual meeting of Society for Biomaterials, in Chicago, Illinois, USA, April 18-21, 2007 6. 簡秀紋 蔡偉博 Controlled cell spatial arrangement by micro-patterned layer-by-layer polyelectrolyte multilayer films 2007 年生物醫學工程科技研討會暨 國科會醫學工程學門成果發表會, 台中, 12 月 14-15 日, 2007 7. 簡秀紋 蔡偉博 Controlled cell spatial adhesion on micropatterned polyelectrolyte multilayer films which are modulated via surface chemistry, 台灣化學工程學會第 54 屆年會暨國科會化工學門成果發表會, 桃園, 11/23-24, 2007 8. 陳英豪 蔡偉博, Inhibition of PEGylated layer-by-layer polyelectrolyte multilayer Film on L929 Cell Adhesion, 台灣化學工程學會第 54 屆年會暨國科會化工學門成 果發表會, 桃園, 11/23-24, 2007 9. 賴耀東 戴子安 蔡偉博 施文彬 馬建清 陳文翔, Fabrication of a new type of artificial sphincter, 台灣化學工程學會第 54 屆年會暨國科會化工學門成果發表會, 桃園, 11/23-24, 2007-211 -
10. 王鵬元 施藹芸 蔡偉博, The influence of scaffold properties and cyclic mechanical compression on cartilage tissue engineering, 台灣化學工程學會第 54 屆年會暨國科 會化工學門成果發表會, 桃園, 11/23-24, 2007 11. 余虹德 蔡偉博, The influences of nanoscale topographic surface on the alignment and differentiation of skeletal muscle myoblasts, 台灣化學工程學會第 54 屆年會暨 國科會化工學門成果發表會, 桃園, 11/23-24, 2007 12. Jia-Hua Lin, Wei-Bor Tsai, Modulation of the adhesion and function of hepatocyte-like cells, HepG2/C3A, on nano-grooved silicon surfaces, at the eighth World Biomaterials Congress, Amsterdam, Netherlands, May 28-June 2, 2008. 13. Kuang-Ling Wei, Shu-Fang Tan, Wei-Bor Tsai, Bio-functionalization of biomaterials by layer-by-layer polyelectrolyte multilayers for modulation of the behavior of osteoblast-like cells, MG-63, at the eighth World Biomaterials Congress, Amsterdam, Netherlands, May 28-June 2, 2008. 14. Peng-Yuan Wang, Ai-Yun Shih, Wei-Bor Tsai, The influence of scaffold properties and dynamic compression on articular cartilage tissue engineering, at the eighth World Biomaterials Congress, Amsterdam, Netherlands, May 28-June 2, 2008. 15. Hsiu-Wen Chien, Tsung-Yao Chang and Wei-Bor Tsai, Controlling cell spatial arrangement by micro-patterned layer-by-layer polyelectrolyte multilayer films, at the eighth World Biomaterials Congress, Amsterdam, Netherlands, May 28-June 2, 2008. 16. Hung-Te Yu, Wei-Bor Tsai, The influences of nano-topographic surfaces on the alignment and differentiation of skeletal myoblasts, at the eighth World Biomaterials Congress, Amsterdam, Netherlands, May 28-June 2, 2008. 17. Hsiu-Wen Chien, Tsung-Yao Chang, Wei-Bor Tsai, Spatial control of cellular adhesion using photo-crosslinked micropatterned polyelectrolyte multilayer films, at the 2009 annual meeting of Society for Biomaterials, San Antonio, Texas, April 22-25, 2009. 18. Peng-Yuan Wang, Hung-Te Yu, Wei-Bor Tsai, The influences of nano-groove/ride surfaces on the alignment and differentiation of skeletal myovlasts, at the 2009 annual meeting of Society for Biomaterials, San Antonio, Texas, April 22-25, 2009. 19. 王鵬元 余虹德 蔡偉博, Alignment and differentiation of skeletal myoblasts on submicron grooved surface, 台灣化學工程學會第 56 屆年會暨國科會化工學門成 果發表會, 台中, 11/27-28, 2009 20. Peng-Yuan Wang, Lauren R. Clements, Wei-Bor Tsai, Helmut Thissen, Nicolas H. Voelcker, "Mesenchymal Stem Cell Differentiation on Laterally Graded Porous Silicon with Submicron Pore Sizes" TERMIS-AP Annual Conference, Sydney, Australia, September 15-17, 2010. 21. Peng-Yuan Wang, Lauren R. Clements, Wei-Bor Tsai, Helmut Thissen, Nicolas H. Voelcker, "Stiffness gradient polydimethylsiloxane (PDMS) for mesenchymal stem cell culture and differentiation" at TERMIS-AP Annual Conference, Sydney, Australia, September 15-17, 2010. - 212 -
22. Peng-Yuan Wang, Jia-Hua Lin, Wei-Bor Tsai, "Interactive effects of surface topography and substrate elasticity on orientation and beating of neonatal rat cardiomycotes" at International Symposium of Materials on Regenerative Medicine, Zhunan, Taiwan, November 3-5, 2010. 23. Peng-Yuan Wang, Wei-Bor Tsai, "Osteogenesis, adipogenesis, and myogenesis of rat mesenchymal stem cells on the nanogrooved surfaces" at The Annual Meeting of the Society For Biomaterials, Orlando, Florida, April 13-16, 2011. 24. 王鵬元 蔡偉博, Osteogenesis, adipogenesis, and myogenesis of rat mesenchymal stem cells on the nanogrooved surfaces 生醫材料與藥物釋放年度會議, 台北, 4/27-28, 2011 25. Wei-Bor Tsai, "UV-Crosslinked Scaffolds for Tissue Engineering" at International Membrane Conference in Taiwan, Chungli, Taiwan, May 26-28, 2011. (Invited talk) 26. Peng-Yuan Wang, Wei-Bor Tsai, "Osteogenesis, adipogenesis, and myogenesis of rat mesenchymal stem cells on the nanogrooved surfaces" at International Membrane Conference in Taiwan, Chungli, Taiwan, May 26-28, 2011. 27. 王鵬元 蔡偉博, Osteogenesis, adipogenesis, and myogenesis of rat mesenchymal stem cells on the nanogrooved surfaces, 第 16 屆生化工程會議, 台北, 6/24-25, 2011 28. 簡志遠 蔡偉博, 多巴胺輔助固定聚乙烯亞胺接枝聚合物以調控細胞與表面的交 互作用, 第 16 屆中華生化工程研討會, 台北, 6/24-25, 2011 29. 王鵬元 蔡偉博, Osteogenesis, adipogenesis, and myogenesis of rat mesenchymal stem cells on the nano/submicron grooved surfaces, 100 年度生醫工程與技術會議, 台南, 8/19-20, 2011 30. 簡志遠 蔡偉博, 多巴胺輔助固定聚乙烯亞胺接枝聚合物以調控細胞與表面的交 互作用,100 年度生物醫學工程科技研討會, 台南, 8/19-20, 2011 31. 林威翰 劉澤英 蔡偉博, UV-crosslinking electrospun gelatin fibers for tissue engineering, 2011 生物醫學工程科技研討會暨國科會醫學工程學門成果發表會, 臺南, 8/19-20, 2011 32. Wei-Bor Tsai, Modulation of Cell Behaviors via Surface Topography and Chemistry at The 4th Asian Conference on Colloid and Interface Science, Tainan, Taiwan, November 23-26, 2011. (Invited talk) 33. Peng-Yuan Wang, Hung-Te Yu, Tsung-Han Wu, Jia-Hua Lin, Wei-Bor Tsai, Modulation of Cell Behaviors via Surface Topography and Chemistry at The 4th Asian Conference on Colloid and Interface Science, Tainan, Taiwan, November 23-26, 2011. - 213 -
34. Wei-Bor Tsai, Chih-Yuan Chien, Peng-Yuan Wang, Dopamine-assisted immobilization of poly(ethylene imine) based polymers for control of cell surface interactions, at The 4th Asian Conference on Colloid and Interface Science, Tainan, Taiwan, November 23-26 2011. 35. 王鵬元, 蔡偉博 Osteogenesis, adipogenesis, and myogenesis of rat mesenchymal stem cells on the nano/submicron grooved surfaces, 台灣化學工程學會第 58 屆年會 暨國科會化工學門成果發表會, 台南, 11/25-26, 2011 36. 簡志遠 蔡偉博, 多巴胺輔助固定聚乙烯亞胺接枝聚合物以調控細胞與表面的交 互作用, 台灣化學工程學會 58 週年年會暨國科會化學工程學門成果發表會, 台南, 11/25-26, 2011 37. 林威翰 劉澤英 蔡偉博, UV-crosslinking electrospun gelatin fibers for tissue engineering, 臺灣化學工程學會第 58 屆年會暨國科會化工學門成果發表會, 臺南, 11/25-26, 2011 Books 1. Glattauer, V., Tsai, W.-B., White, J.F., Nigro, J., Tebb, T.A., Werkmeister, J.A. and Ramshaw, J.A.M. (2011) Direct use of resorbable collagen-based beads for cell delivery in tissue engineering and cell therapy applications. In; Regenerative medicine and tissue engineering -cells and biomaterials (Eberli, D., Ed.), InTech Publishing, Rijeka Cr, pp. 261-286. 2. Weng-Jiy Wang and W.-B. Tsai*. Biomaterials in Blood-Contacting Devices complications and Solutions. in Biomaterials Properties, production and devices series. Nova Science Publishers, Inc, New York. 2010. ISBN: 978 1 60876 784 7. Patents 1. 使用一裝置在製造一醫藥用品上之用途 製造一供修補一主體中害病的或受損 的組織之裝置的方法以及具類似組織特性之裝置, 中華民國專利, 證書號 :I258372, 2006/07/21-2022/02/03. - 214 -