HyPerforma Single-Use Mixer DS 300

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HyPerforma Single-Use Mixer DS 300 Achieve greater process flexibility

Increased mobility, smaller footprint The Thermo Scientific HyPerforma Single-Use Mixer DS 300 (S.U.M.) is built upon the proven legacy design of our S.U.M. and docking station, but it has been optimized for lower-cost, high-throughput applications. The smaller footprint and lighter weight of the HyPerforma S.U.M. DS 300 provide mobility and flexibility in mixing applications. 2

Technology Modular mixing for enhanced process efficiency The HyPerforma S.U.M. DS 300 is a modular mixing station with features designed for simplicity and performance. The system utilizes a top-mounted mixing motor with an angular drive shaft. This industry-accepted design eliminates vortices, enables effi cient mixing, and provides more power. Mobility the ergonomically designed mixing station provides enhanced ease of use. Modularity choose from multiple drum sizes, mixing shafts, and mixing head heights to confi gure the modular solution for your bioprocessing applications. Applications Preparation has never been simpler The HyPerfoma S.U.M. DS 300 can be used in powder-liquid and liquid-liquid mixing applications. By utilizing our proven technology, you can use the same top-mounted mixing design to assure quality and minimize the need for multiple mixers in your process. It can be used for: Hydration powdered media and buffers Sterile mixing buffer solutions, cell culture media with sera and reagents, or other process fl uids Pooling sterile liquid fractions Interoperability specifi cally designed to combine mixing across multiple scales in one mixing station by attaching to drums of four different sizes (50 L, 100 L, 200 L, and 300 L). 3

Benefi ts Do more with less Investment capital and space are precious resources the HyPerforma S.U.M. DS 300 addresses both. Reduce capital investment across multiple mixing applications by docking and mixing in multiple plastic drums Adapt your process with 50 L, 100 L, 200 L, and 300 L sizes of mixing drums Mix effi ciently at lower volumes with the 5:1 turndown ratio Increase mobility with a smaller footprint and lighter weight Accessories Create the custom solution that meets your needs Plastic drums mix and move Use all or a few of the portable plastic drums in the sizes that you need. These multifunctional drums are easily moved to cold rooms and stored until you need them. BioProcess Containers ship and store Implement industry-proven Thermo Scientifi c BioProcess Containers (BPCs) in the overall process of shipping and storing your liquid-liquid and powder-liquid bioprocess mixing applications. BPC systems come in an open- and closed-top design, and are manufactured using our high-performance single-use fi lm. Direct drive design drastically reduces particulate generation Capable of open- and closed-top mixing Suitable for both powder-liquid and liquid-liquid applications 4

Technical support: knowledgeable and comprehensive Our global field-based technical support team is here to help you every step of the way with local installation and technical support. We can also provide you with additional support documentation upon request. All systems are supplied with: Comprehensive user s guide Equipment turnover package Validation guide Find out more about the HyPerforma S.U.M. DS 300 The complete HyPerforma S.U.M. DS 300 mixing platform consists of a portable mixing station, a drum, and a BPC system. To learn more about the entire platform or to request a demo, go to thermofisher.com/sut 5

Specifications and ordering information HyPerforma S.U.M. DS 300 Specifications Electrical power supply requirement 108 240 VAC; 50 60 Hz; single phase (voltage, frequency, phase) Input amperage 15 amps Footprint (D x H) 86.4 cm (34.0 in.) x 76.2 cm (30.0 in.) Height 122.4 cm (48.19 in.) low; 162.4 cm (63.93 in.) high Weight 180 kg (398 lbs) Control box Built to IP65 standards Lift range 40 cm (15.7 in.) Flow type Radial/axial Mixing rate 30 350 RPM Impeller to BioProcess Container location 5:1 off center Impeller (quantity x blade count) 1 x 3 Counterclockwise mixing-flow direction Down-pumping Mixing Containers Specifications 50 L 100 L 200 L 300 L Turndown ratio 5:1 5:1 5:1 4:1* Footprint (D x H) 59.7 x 58 cm (23.5 x 23 in.) 59.7 x 75.57 cm (23.5 x 29.75 in.) 59.7 x 113.7 cm (23.5 x 44.75 in.) 61 x 122 cm (24 x 48 in.) Hardware material Plastic (LLDPE) Impeller sleeve Specifications Impeller material Impeller sleeve with Quick Connect USP Class VI, HDPE C-Flex tubing * 5:1 turndown ratio with adjustable motor head. HyPerforma S.U.M. DS 300 Cat. No. SUMDS0300.9000 SUMDS0300.9001 SUMDS0300.9002 SUMDS0300.9003 Description DS 300 unit; 108 240 VAC, 50 to 60 Hz DS 300 unit; 108 240 VAC, 50 to 60 Hz with drum positioner DS 300 unit; 108 240 VAC, 50 to 60 Hz with adjustable motor head DS 300 unit; 108 240 VAC, 50 to 60 Hz with drum positioner and adjustable motor head 6

Ordering information Drums and drum dollies Cat. No. Description Size SH30959.01 Drum with bottom-drain port 50 L SH30959.02 Drum with bottom-drain port 100 L SH30959.03 Drum with bottom-drain port 200 L SH30959.04 Drum 300 L SV50102.02 Optional support plate for bottom-drain port 50 L 200 L SH30958.01 Plastic dolly (single pack) 50 L 200 L SH30958.02 Plastic dolly (2-pack of SH30958.01) 50 L 200 L SH30958.03 Stainless steel dolly 300 L Tank liners Cat. No. Description Size SH30646.01 Open-top with bottom drain, irradiated, CX 5-14 film 50 L SH30646.02 Open-top with bottom drain, irradiated, CX 5-14 film 100 L SH30646.03 Open-top with bottom drain, irradiated, CX 5-14 film 200 L SH30647.06 Open-top with top drain only, irradiated, CX 5-14 film 300 L SH30988.01 Open-top with bottom drain, irradiated, Aegis 5-14 film 50 L SH30988.02 Open-top with bottom drain, irradiated, Aegis 5-14 film 100 L SH30988.03 Open-top with bottom drain, irradiated, Aegis 5-14 film 200 L SH30399.01 Open-top with bottom drain, non-irradiated, CX 5-14 film 50 L SH30399.02 Open-top with bottom drain, non-irradiated, CX 5-14 film 100 L SH30399.03 Open-top with bottom drain, non-irradiated, CX 5-14 film 200 L BioProcess Containers Cat. No. Description Size SH30946.01 Closed-top with bottom drain, irradiated 50 L SH30946.02 Closed-top with bottom drain, irradiated 100 L SH30946.03 Closed-top with bottom drain, irradiated 200 L Impeller sleeves Cat. No. Description Size (volume, length) SH30749.11 For use with reusable hub and open-top BPC tank liner 50 L, 35.3 cm (13.9 in.) SH30749.12 For use with reusable hub and open-top BPC tank liner 100 L, 53.1 cm (20.9 in.) SH30749.13 For use with reusable hub and open-top BPC tank liner 200 L, 77 cm (30.3 in.) SH30749.08 For use with reusable hub and open-top BPC tank liner 300 L, 94.9 cm (37.8 in.) Reusable hub Cat. No. Description Size SV50177.77 For use with impeller sleeve and open-top BPC tank liner 50 L 300 L 7

Integrated solutions for bioproduction Single-Use Mixers (S.U.M.s) A variety of options up to 5,000 L for both upstream and downstream applications Liquid- and dry-format media We offer both custom manufacturing and a full range of chemically defi ned performance media and supplement products BioProcess Containers (BPCs) A variety of confi gurations up to 2,000 L for liquid harvest, storage, and transportation Sera Our sera are the industry standards for consistent quality and reliability Single-Use Bioreactors (S.U.B.s) 50 2,000 L bioreactors capable of integrating with an existing control system Buffers and process liquids Custom and standard buffers and process liquids, including Gibco Water For Injection (WFI) quality water Integrity testing systems A true point-of-use integrity testing system to confi rm the integrity of BPCs before use Find out more at thermofisher.com/sum For Research Use or Further Manufacturing. Not for diagnostic use or direct administration into humans or animals. 2017 Thermo Fisher Scientifi c Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientifi c and its subsidiaries unless otherwise specifi ed. C-Flex is a trademark of the Saint-Gobain Performance Plastics Corp. COL01680 0717