Global PNH & ahus Market: Industry Analysis & Outlook ( )

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1 Industry Research by Koncept Analytics Global PNH & ahus Market: Industry Analysis & Outlook October 2017 Global PNH and ahus Market: Industry Analysis & Outlook 1

2 Executive Summary PNH and ahus, both are extremely rare and genetic diseases. Due to PNH, destruction of red blood cells of a person occur quite sooner than it should. It is an acquired hematopoietic stem cell disorder. Hematopoietic stem cells are developed in bone marrow and eventually turn into red blood cells, white blood cells and platelets. A person with PNH has some defected hematopoietic cells which create defective red blood cells. These defective cells are highly susceptible to premature destruction by the complement system. ahus is a disorders in which blood clots are formed in small blood vessels throughout the body. TMA can lead to heart stroke, attack, kidney failure and death. Soliris is the only drug treatment available in the market for treating these diseases. Regionally, Europe held the largest share in the global PNH drug market and the U.S. dominated the global ahus drug market, supported by favorable reimbursement policies In terms of patient population, Asia-pacific region had the highest number of PNH and ahus patients. With the increasing technological advancements in diagnosis techniques of PNH and ahus, the number of diagnosed patients is likely to grow globally. The global PNH and ahus market is expected to grow in future due to prolonged orphan drug market exclusivity, attractive orphan drug policies, increasing pharmaceutical R&D expenditure, rising health care expenditure. Key trends of this market includes progressing drugs under pipeline, increasing prevalence of blood and bone marrow related disorders and favorable reimbursement policies. However, there are some factors which can hinder the market growth including high costs of drugs and associated risks. The report Global PNH and ahus Market: Industry Analysis & Outlook by Koncept Analytics provides an extensive research and detailed analysis of the present market along with future outlook. The report discusses the major growth drivers and challenges of the market, covering the U.S., Europe and Asia- Pacific region along with the global market. The report profiles the key players of the market including Alexion Pharmaceuticals Inc., Alnylam Pharmaceuticals Inc, Omeros Corporation and RA Pharmaceuticals. Global PNH and ahus Market: Industry Analysis & Outlook 2

3 US$ Million Thousand Increasing prevalence of blood and bone marrow related disorders is expected to boost the global PNH patient population Global PNH Patient Population Forecast ( ) Global PNH patient population is expected to reach..thousand in the year 2021, increasing from..thousand in the year 2016 at a CAGR of..% for period spanning In the year 2021, global PNH drug market value is expected to reach US$.. million, increasing from US$.. million in 2016, growing at a CAGR of..% for period spanning In 2016, Europe held the largest share of..% in global PNH drug market, followed by the U.S. with a share of..%. Total Diagnosed Patients Global PNH Drug Market Value Forecast ( ) Global PNH Drug Market Value by Region (2016) Soliris ALXN1210 Europe The U.S. Asia-Pacific ROW Global PNH and ahus Market: Industry Analysis & Outlook 3

4 US$ Million Thousand Global ahus market is likely to grow with increasing technological advancements in diagnosis methods and rising investments in research and development of ahus drugs.. Global ahus Patient Population Forecast ( ) Global ahus patient population is expected to reach thousand in the year 2021, increasing from..thousand in the year 2016 at a CAGR of..% for period In the year 2021, global ahus drug market value is predicted to reach US$.. million, increasing from US$.. million in 2016, recording growth at a CAGR of..% for period The U.S. held the largest share of..% in the global ahus drug market, followed by Europe with a share of..% in Total Newly Diagnosed Patients per Year Global ahus Drug Market Value Forecast ( ) Global ahus Drug Market Value by Region (2016) Soliris ALXN1210 The U.S. Europe Asia-Pacific ROW Global PNH and ahus Market: Industry Analysis & Outlook 4

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